KEGG   ORTHOLOGY: K05830
Entry
K05830                      KO                                     
Symbol
lysJ, argD
Name
[amino-group carrier protein]-gamma-(L-lysyl/L-ornithyl)-L-glutamate aminotransferase [EC:2.6.1.118 2.6.1.124]
Pathway
map00220  Arginine biosynthesis
map00300  Lysine biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
map01210  2-Oxocarboxylic acid metabolism
map01230  Biosynthesis of amino acids
Module
M00031  Lysine biosynthesis, mediated by LysW, 2-aminoadipate => lysine
M00763  Ornithine biosynthesis, mediated by LysW, glutamate => ornithine
Reaction
R09778  LysW-gamma-L-lysine:2-oxoglutarate 6-aminotransferase
R10932  LysW-L-ornithine:2-oxoglutarate 5-aminotransferase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00300 Lysine biosynthesis
    K05830  lysJ, argD; [amino-group carrier protein]-gamma-(L-lysyl/L-ornithyl)-L-glutamate aminotransferase
   00220 Arginine biosynthesis
    K05830  lysJ, argD; [amino-group carrier protein]-gamma-(L-lysyl/L-ornithyl)-L-glutamate aminotransferase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01007 Amino acid related enzymes
    K05830  lysJ, argD; [amino-group carrier protein]-gamma-(L-lysyl/L-ornithyl)-L-glutamate aminotransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.6  Transferring nitrogenous groups
   2.6.1  Transaminases
    2.6.1.118  [amino-group carrier protein]-gamma-(L-lysyl)-L-glutamate aminotransferase
     K05830  lysJ, argD; [amino-group carrier protein]-gamma-(L-lysyl/L-ornithyl)-L-glutamate aminotransferase
    2.6.1.124  [amino-group carrier protein]-gamma-(L-ornithyl)-L-glutamate aminotransferase
     K05830  lysJ, argD; [amino-group carrier protein]-gamma-(L-lysyl/L-ornithyl)-L-glutamate aminotransferase
Amino acid related enzymes [BR:ko01007]
 Aminotransferase (transaminase)
  Class III
   K05830  lysJ, argD; [amino-group carrier protein]-gamma-(L-lysyl/L-ornithyl)-L-glutamate aminotransferase
Other DBs
COG: COG0160 COG4992
Genes
MICZ: GL2_37030(argD_2)
PPAK: JY651_29855
KIB: RBB56_17180
GEK: kuro4_23310(argD)
RRS: RoseRS_2722
RCA: Rcas_3460
CAU: Caur_3656
CHL: Chy400_3943
CAG: Cagg_0221
HAU: Haur_3309
ATM: ANT_12380(argD)
LEK: hrd7_27830(argD)
CAP: CLDAP_41060(argD)
TTR: Tter_0321
TRO: trd_1515
STI: Sthe_0219
DRA: DR_0794
DGE: Dgeo_1416
DDR: Deide_16910(argD)
DFC: DFI_08425
DGA: DEGR_15170(argD_1)
DAH: DAETH_22810(argD_2)
TRA: Trad_1401
TTH: TT_C1393
TTJ: TTHA1755(TTHA1755)
TSC: TSC_c03550(rocD)
TAQ: TO73_0260
TAI: Taci_0450
TLI: Tlie_1472
MRO: MROS_0161
CABY: Cabys_1935 Cabys_3152(argD)
PFU: PF1685
PFI: PFC_10180(argD)
PHO: PH1716(PH1716)
PAB: PAB2440(argD)
PYN: PNA2_0326
PYS: Py04_1633
TKO: TK0275
THS: TES1_0510
HHB: Hhub_3651(argD)
HALH: HTSR_0667(argD)
HHSR: HSR6_0693(argD)
HSU: HLASF_2140(argD)
HSF: HLASA_2174(argD)
HAHS: HSRCO_2862(argD)
SALI: L593_07900
HARA: AArcS_3064(argD)
HMA: rrnAC2675(argD)
HHI: HAH_3080(argD)
NPH: NP_5264A(argD)
NMO: Nmlp_1240(argD)
HUT: Huta_1499
HTI: HTIA_1542
HASV: SVXHr_0127(argD)
HABN: HBNXHr_0124(argD)
HMU: Hmuk_0775
HALL: LC1Hm_3291(argD)
HDS: HSR122_1702(argD)
HWA: HQ_3717A(argD)
HWC: Hqrw_4132(argD)
HVO: HVO_0043(argD)
HLN: SVXHx_0041(argd)
HME: HFX_0043(argD)
HLA: Hlac_2613
HDF: AArcSl_0040(argD)
HAAA: AArcCO_0042(argD)
HTU: Htur_0325
NMG: Nmag_1758(argD)
NAT: NJ7G_0260
PTO: PTO1470
FAI: FAD_0507(lysJ)
CDIV: CPM_0546
APE: APE_1464(lysJ)
ACJ: ACAM_0924(lysJ)
IHO: Igni_0944
IIS: EYM_01870
IPC: IPA_05460
IAG: Igag_1751
PABI: PABY_17840
PARE: PYJP_07940
STO: STK_01910(argD_lysJ)
SSO: SSO0160(argD)
SOL: Ssol_1138
SSOA: SULA_1174
SSOL: SULB_1175
SSOF: SULC_1173
SCAS: SACC_00730
SAI: Saci_0755(argD)
SID: M164_1985
SII: LD85_2240
SIH: SiH_1923
SIR: SiRe_1850
SIC: SiL_1832
MSE: Msed_0169
MEMJ: MJ1HA_0248
MCN: Mcup_1904
AHO: Ahos_0888
ACIH: HS5_22630
CSTY: KN1_18120
STEP: IC006_1907
PAI: PAE2515
PIS: Pisl_1923
PCL: Pcal_0283
PAS: Pars_1404
PYR: P186_1106
POG: Pogu_0801
TNE: Tneu_1167
CMA: Cmaq_0767
TTN: TTX_0623(lysJ_argD)
TUZ: TUZN_0263
VDI: Vdis_0197
KCR: Kcr_0813
NMR: Nmar_1291
NID: NPIRD3C_0833(argD)
NIN: NADRNF5_0665(argD)
NCT: NMSP_0397(hemL_1)
NGA: Ngar_c29940(argD2)
NVN: NVIE_016480(argD1)
NEV: NTE_00736
TAA: NMY3_02224(argD)
NFN: NFRAN_2986(argD)
NCV: NCAV_1249(argD)
NBV: T478_1046(argD)
NDV: NDEV_1626(argD)
CCAI: NAS2_0269
BARB: AOA66_0022(hemL_1)
 » show all
Reference
  Authors
Miyazaki J, Kobashi N, Nishiyama M, Yamane H
  Title
Functional and evolutionary relationship between arginine biosynthesis and prokaryotic lysine biosynthesis through alpha-aminoadipate.
  Journal
J Bacteriol 183:5067-73 (2001)
DOI:10.1128/JB.183.17.5067-5073.2001
  Sequence
[tth:TT_C1393]
Reference
  Authors
Horie A, Tomita T, Saiki A, Kono H, Taka H, Mineki R, Fujimura T, Nishiyama C, Kuzuyama T, Nishiyama M
  Title
Discovery of proteinaceous N-modification in lysine biosynthesis of Thermus thermophilus.
  Journal
Nat Chem Biol 5:673-9 (2009)
DOI:10.1038/nchembio.198
Reference
  Authors
Ouchi T, Tomita T, Horie A, Yoshida A, Takahashi K, Nishida H, Lassak K, Taka H, Mineki R, Fujimura T, Kosono S, Nishiyama C, Masui R, Kuramitsu S, Albers SV, Kuzuyama T, Nishiyama M
  Title
Lysine and arginine biosyntheses mediated by a common carrier protein in Sulfolobus.
  Journal
Nat Chem Biol 9:277-83 (2013)
DOI:10.1038/nchembio.1200
  Sequence
[sai:Saci_0755]
LinkDB

KEGG   REACTION: R10932
Entry
R10932                      Reaction                               
Name
LysW-L-ornithine:2-oxoglutarate 5-aminotransferase
Definition
LysW-L-glutamate 5-semialdehyde + L-Glutamate <=> LysW-L-ornithine + 2-Oxoglutarate
Equation
Reaction class
RC00006  C00025_C00026
RC00062  C20950_C20951
Enzyme
2.6.1.-
Pathway
rn00220  Arginine biosynthesis
rn01100  Metabolic pathways
rn01210  2-Oxocarboxylic acid metabolism
rn01230  Biosynthesis of amino acids
Module
M00763  Ornithine biosynthesis, mediated by LysW, glutamate => ornithine
Brite
Enzymatic reactions [BR:br08201]
 2. Transferase reactions
  2.6  Transferring nitrogenous groups
   2.6.1  Transaminases
    2.6.1.-
     R10932  LysW-L-glutamate 5-semialdehyde + L-Glutamate <=> LysW-L-ornithine + 2-Oxoglutarate
Orthology
K05830  [amino-group carrier protein]-gamma-(L-lysyl/L-ornithyl)-L-glutamate aminotransferase [EC:2.6.1.118 2.6.1.124]
Other DBs
RHEA: 52675
LinkDB

DBGET integrated database retrieval system