KEGG ORTHOLOGY: K06779

ORTHOLOGY: K06779

Entry

K06779                      KO

Symbol

MADCAM1

Name

mucosal vascular addressin cell adhesion molecule 1

Pathway

map04514

Cell adhesion molecule (CAM) interaction

map04518

Integrin signaling

map04672

Intestinal immune network for IgA production

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04514 Cell adhesion molecule (CAM) interaction
    K06779  MADCAM1; mucosal vascular addressin cell adhesion molecule 1
   04518 Integrin signaling
    K06779  MADCAM1; mucosal vascular addressin cell adhesion molecule 1
09150 Organismal Systems
  09151 Immune system
   04672 Intestinal immune network for IgA production
    K06779  MADCAM1; mucosal vascular addressin cell adhesion molecule 1
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04515 Cell adhesion molecules
    K06779  MADCAM1; mucosal vascular addressin cell adhesion molecule 1
Cell adhesion molecules [BR:ko04515]
Immunoglobulin superfamily
  Other
   K06779  MADCAM1; mucosal vascular addressin cell adhesion molecule 1

Genes

HSA:	8174(MADCAM1)

PTR:	104003219(MADCAM1)

PPS:	100973901(MADCAM1)

GGO:	129528793(MADCAM1)

PON:	100446547(MADCAM1)

PPYG:

129026090(MADCAM1)

NLE:	100597148 115831193

HMH:	116464372(MADCAM1)

SSYN:

129465507(MADCAM1)

MCC:	721034(MADCAM1)

MCF:	102125701(MADCAM1)

MTHB:

126942998

MNI:

105487314

CSAB:

103233562(MADCAM1)

CATY:

105591671(MADCAM1)

TGE:	112612304(MADCAM1)

MLEU:

105548834(MADCAM1)

RRO:	104681453(MADCAM1)

TFN:	117076430(MADCAM1)

PTEH:

111532451(MADCAM1)

CANG:

105527598(MADCAM1)

CIMI:

108297489(MADCAM1)

ANAN:

105705885(MADCAM1)

CSYR:

103251751(MADCAM1)

MMUR:

105860826(MADCAM1)

LCAT:

123632103(MADCAM1)

ERUF:

138397655(MADCAM1)

PCOQ:

105811243(MADCAM1)

OGA:	100961624(MADCAM1)

MMU:	17123(Madcam1)

MCAL:

110303908(Madcam1)

MPAH:

110326961(Madcam1)

RNO:	54266(Madcam1)

MCOC:

116076384(Madcam1)

ASYL:

127671033(Madcam1)

MUN:	110551321(Madcam1)

CGE:	100750395(Madcam1)

MAUA:

101844424(Madcam1)

PROB:

127216669(Madcam1)

PLEU:

114684113(Madcam1)

MORG:

121459690(Madcam1)

MFOT:

126489232

AAMP:

119804464(Madcam1)

NGI:	103737405(Madcam1)

HGL:	101723568(Madcam1)

CPOC:

100722478(Madcam1)

CCAN:

109686100(Madcam1)

DORD:

105990388(Madcam1)

DSP:	122122819(Madcam1)

DMER:

138817493(Madcam1)

PLOP:

125347921(Madcam1)

NCAR:

124975384

ITI:	101960984(Madcam1)

OCU:

103347357

OPI:	101528181(MADCAM1)

OCZ:	121162970(MADCAM1)

TUP:	102491637(MADCAM1)

GVR:	103600240(MADCAM1)

CFA:	485103(MADCAM1)

CLUD:

112666143(MADCAM1)

VVP:	112935587(MADCAM1)

VLG:	121495718(MADCAM1)

NPO:	129522115(MADCAM1)

AML:	100475332(MADCAM1)

UMR:	103681755(MADCAM1)

UAH:	113242691(MADCAM1)

UAR:	123794068(MADCAM1)

ELK:

111161898

LLV:

125087516

MPUF:

101691774(MADCAM1)

MNP:	132009632(MADCAM1)

MLK:	131823146(MADCAM1)

NVS:	122910833(MADCAM1)

ORO:	101383831(MADCAM1)

EJU:	114226110(MADCAM1)

ZCA:	113917328(MADCAM1)

MLX:	118005075(MADCAM1)

MANO:

123834884(MADCAM1)

NSU:	110593965(MADCAM1)

LWW:	102745863(MADCAM1) 115943452

FCA:	101089986(MADCAM1)

PYU:	121021884(MADCAM1)

PCOO:

112852753(MADCAM1)

PBG:	122486603(MADCAM1)

PVIV:

125159760(MADCAM1)

LRUF:

124527645

LGF:	123604943(MADCAM1)

AJU:

106978110

PTG:	102954047(MADCAM1)

PPAD:

109257665(MADCAM1)

PUC:

125928766

PLEZ:

122213254(MADCAM1)

HHV:	120242334(MADCAM1)

CCRU:

144228691(MADCAM1)

BTA:	527275(MADCAM1)

BOM:	102276732(MADCAM1)

BIU:	109561258(MADCAM1)

BJV:	133251162(MADCAM1)

BBUB:

102404914(MADCAM1)

BKE:	129642200(MADCAM1)

BBIS:

104991918(MADCAM1)

CHX:	102170227(MADCAM1)

OAS:	654333(MADCAM1)

OCAN:

138440339(MADCAM1)

BTAX:

128051652(MADCAM1)

CSUM:

138086563(MADCAM1)

ODA:	120863742(MADCAM1)

MREE:

136156041(MADCAM1)

OVR:	110142294(MADCAM1)

MBEZ:

129558927(MADCAM1)

SSC:	492312(MADCAM1)

CFR:	102514595(MADCAM1)

CBAI:

105078099(MADCAM1)

CDK:	105093405(MADCAM1)

VPC:	102526373(MADCAM1)

BACU:

103019742(MADCAM1)

BMUS:

118892848(MADCAM1)

LVE:	103088298(MADCAM1)

OOR:	101280382(MADCAM1)

LALB:

132518771(MADCAM1)

GMF:	115846694(MADCAM1)

DDP:	132421698(MADCAM1)

DLE:	111170504(MADCAM1)

PCAD:

102980844(MADCAM1)

PSIU:

116751602(MADCAM1)

PPHC:

136120477(MADCAM1)

ECB:	102149135(MADCAM1)

EPZ:	103543215(MADCAM1)

EAI:	106834260(MADCAM1)

MYB:	102252395(MADCAM1)

MYD:	102752952(MADCAM1)

MMYO:

118657595(MADCAM1)

MLF:	102432785(MADCAM1)

MDT:	132235313(MADCAM1)

MYUM:

139010735(MADCAM1)

PKL:	118711799(MADCAM1)

EFUS:

103294443(MADCAM1)

MNA:	107538561(MADCAM1)

DRO:	112312295(MADCAM1)

SHON:

118984371(MADCAM1)

AJM:	119044618(MADCAM1)

PDIC:

114503600(MADCAM1)

PHAS:

123814073(MADCAM1)

MMF:	118643506(MADCAM1)

PPAM:

129072429(MADCAM1)

HAI:	109390664(MADCAM1)

RFQ:	117038210(MADCAM1)

PALE:

102886454(MADCAM1)

PGIG:

120587406

PVP:	105302277(MADCAM1)

RAY:	107500899(MADCAM1)

MJV:	108391743(MADCAM1)

TOD:	119240356(MADCAM1)

SARA:

101550785(MADCAM1)

SFUM:

130022225(MADCAM1)

SETR:

126030025(MADCAM1)

TMU:

101359467

ETF:	101658314(MADCAM1)

DNM:	101447757(MADCAM1)

MDO:	100024786(MADCAM1)

GAS:	123244188(MADCAM1)

PCW:	110223337(MADCAM1)

TVP:	118843842(MADCAM1)

PBRV:

138142586(MADCAM1)

OAA:	114806501(MADCAM1)

TACU:

119919586(MADCAM1)

GGA:	100858236(MADCAM1)

PCOC:

116235829(MADCAM1)

MGP:	104914694(MADCAM1)

CJO:	107325549(MADCAM1)

TPAI:

128090375(MADCAM1)

LMUT:

125685010(MADCAM1)

NMEL:

110388894(MADCAM1)

APLA:

110354692(MADCAM1)

AACU:

137844756(MADCAM1)

ACYG:

106049093(MADCAM1)

CATA:

118260059(MADCAM1)

AFUL:

116499221(MADCAM1)

TGU:	105758938(MADCAM1)

LSR:	110475779(MADCAM1)

SCAN:

103821942(MADCAM1)

PMOA:

120513593(MADCAM1)

OTC:	121342219(MADCAM1)

PRUF:

121360977(MADCAM1)

ATRC:

139602111(MADCAM1)

GFR:	102034808(TPGS1)

FAB:	101821691(MADCAM1)

OMA:	130264472(MADCAM1)

PHI:	102099722(MADCAM1)

PMAJ:

107215431(MADCAM1)

CCAE:

111942106(MADCAM1)

CCW:	104697043(MADCAM1)

CBRC:

103622128(MADCAM1)

ACOE:

138099781(MADCAM1)

ETL:	114066356(MADCAM1)

ZAB:	102069433(MADCAM1)

ZLE:	135458874(MADCAM1)

SVG:	106857071(MADCAM1)

MMEA:

130580208(MADCAM1)

HRT:	120763464(MADCAM1)

SATI:

136371867(MADCAM1)

CCIC:

134054375(MADCAM1)

FPG:	101919262(MADCAM1)

FCH:	102050067(MADCAM1)

CCRI:

104159639(MADCAM1)

SHAB:

115618312(MADCAM1)

TALA:

116961632(MADCAM1)

ACHC:

115349116(MADCAM1)

HLE:	104829151(MADCAM1)

AGEN:

126041752

HHAR:

128148045(MADCAM1)

BBUT:

142035366(MADCAM1)

GCL:

127025573

CSTI:

104557595(MADCAM1)

DPUB:

104300726(MADCAM1)

PPUS:

135192138(MADCAM1)

EGZ:	104124437(MADCAM1)

NNI:	104016264(MADCAM1)

PCRI:

104027120(MADCAM1)

PARX:

142049527(MADCAM1)

PADL:

103923483

AFOR:

103899432 103899433(MADCAM1)

CBOR:

142093691(MADCAM1)

GSTE:

104264135(MADCAM1)

CBOY:

140643701(MADCAM1)

MAME:

142420517(MADCAM1)

CLV:	102089262(MADCAM1)

CNIC:

135999272(MADCAM1)

PLET:

104623840(MADCAM1)

CUCA:

104067732(MADCAM1)

CVF:	104294390(MADCAM1)

RTD:	128900706(MADCAM1)

CRID:

134526367(MADCAM1)

LMIC:

141734363(MADCAM1)

AAM:	106486385(MADCAM1)

AROW:

112973870(MADCAM1)

ASN:	102369527(MADCAM1)

AMJ:	102568700(MADCAM1)

CPOO:

109312279(MADCAM1)

GGN:	109294915(MADCAM1)

CIZ:	142002341(MADCAM1)

CMY:	114022440(MADCAM1)

CCAY:

125627068(MADCAM1)

LKP:	140903419(MADCAM1)

NDS:	141977750(MADCAM1)

DCC:	119848182(MADCAM1)

CPIC:

101948815(MADCAM1)

TST:	117868867(MADCAM1)

CABI:

116825864(MADCAM1)

MRV:	120391585(MADCAM1)

EMQ:	137160313(MADCAM1)

ASAO:

132781480(MADCAM1)

PVT:	110079306(MADCAM1)

SUND:

121936769(MADCAM1)

PBI:	112541162(MADCAM1)

PMUR:

107299571(MADCAM1)

PCAE:

139308357(MADCAM1)

PTEX:

113435343(MADCAM1)

NSS:	113425095(MADCAM1)

PMUA:

114588693(MADCAM1)

PRAF:

128405861(MADCAM1)

ZVI:	118087154(MADCAM1)

HCG:	128348089(MADCAM1)

STOW:

125433262(MADCAM1)

EMC:	129331182(MADCAM1)

XLA:

108695244

XTR:	100487740(madcam1)

RTEM:

120910130(MADCAM1)

BBUF:

120991602(MADCAM1)

BGAR:

122930845(MADCAM1)

DTC:	141098468(ICAM4)

MUO:	115480062(MADCAM1)

SASA:

OTW:

OMY:

OGO:

SALP:

SNH:

Reference

PMID:8609404

Authors

Shyjan AM, Bertagnolli M, Kenney CJ, Briskin MJ

Title

Human mucosal addressin cell adhesion molecule-1 (MAdCAM-1) demonstrates structural and functional similarities to the alpha 4 beta 7-integrin binding domains of murine MAdCAM-1, but extreme divergence of mucin-like sequences.

Journal

J Immunol 156:2851-7 (1996)

Sequence

[hsa:8174]

Reference

PMID:15483224

Authors

Ogawa H, Binion DG, Heidemann J, Theriot M, Fisher PJ, Johnson NA, Otterson MF, Rafiee P

Title

Mechanisms of MAdCAM-1 gene expression in human intestinal microvascular endothelial cells.

Journal

Am J Physiol Cell Physiol 288:C272-81 (2005)
DOI:10.1152/ajpcell.00406.2003

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