KEGG ORTHOLOGY: K07512

ORTHOLOGY: K07512

Entry

K07512                      KO

Symbol

MECR, NRBF1

Name

mitochondrial enoyl-[acyl-carrier protein] reductase / trans-2-enoyl-CoA reductase [EC:1.3.1.- 1.3.1.38]

Pathway

map00061

Fatty acid biosynthesis

map00062

Fatty acid elongation

map01100

Metabolic pathways

map01212

Fatty acid metabolism

Module

M00085

Fatty acid elongation in mitochondria

M00873

Fatty acid biosynthesis in mitochondria, animals

M00874

Fatty acid biosynthesis in mitochondria, fungi

Reaction

R01278

hexadecanoyl-CoA:NADP+ trans-2-oxidoreductase

R01404

acyl-[acyl-carrier protein]:NADP+ oxidoreductase

R03776

trans-Oct-2-enoyl-CoA reductase

R03856

trans-dodec-2-enoyl-CoA reductase

R03989

trans-tetradec-2-enoyl-CoA reductase

R04430

butyryl-[acp]:NADP+ trans-2-oxidoreductase

R04725

dodecanoyl-[acp]:NADP+ trans-2-oxidoreductase

R04753

trans-Dec-2-enoyl-CoA reductase

R04956

hexanoyl-[acp]:NADP+ trans-2-oxidoreductase

R04959

octanoyl-[acp]:NADP+ trans-2-oxidoreductase

R04962

decanoyl-[acp]:NADP+ trans-2-oxidoreductase

R04967

tetradecanoyl-[acp]:NADP+ trans-2-oxidoreductase

R04970

hexadecanoyl-[acp]:NADP+ trans-2-oxidoreductase

R06985

trans-Hex-2-enoyl-CoA reductase

R07162

acyl-CoA:NADP+ trans-2-oxidoreductase

Disease

H00831

Primary dystonia

H01020

Optic atrophy

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09103 Lipid metabolism
   00061 Fatty acid biosynthesis
    K07512  MECR, NRBF1; mitochondrial enoyl-[acyl-carrier protein] reductase / trans-2-enoyl-CoA reductase
   00062 Fatty acid elongation
    K07512  MECR, NRBF1; mitochondrial enoyl-[acyl-carrier protein] reductase / trans-2-enoyl-CoA reductase
Enzymes [BR:ko01000]
1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.38  trans-2-enoyl-CoA reductase (NADPH)
     K07512  MECR, NRBF1; mitochondrial enoyl-[acyl-carrier protein] reductase / trans-2-enoyl-CoA reductase

Other DBs

GO:

0019166

Genes

HSA:	51102(MECR)

PTR:	456690(MECR)

PPS:	100993891(MECR)

GGO:	101131268(MECR)

PON:	100457156(MECR)

PPYG:

129042045(MECR)

NLE:	100598490(MECR)

HMH:	116813191(MECR)

SSYN:

129472019(MECR)

MCC:	717425(MECR)

MCF:	102121965(MECR)

MTHB:

126957718

MNI:	105494580(MECR)

CSAB:

103225243(MECR)

CATY:

105594863(MECR)

PANU:

101017534(MECR)

TGE:	112604899(MECR)

MLEU:

105540957(MECR)

RRO:	104675685(MECR)

RBB:	108530045(MECR)

TFN:	117092992(MECR)

PTEH:

111547589(MECR)

CANG:

105521316(MECR)

CJC:	100393592 100403337(MECR)

SBQ:	101029298(MECR)

CIMI:

108308792(MECR)

ANAN:

105708481(MECR)

CSYR:

103255734(MECR)

MMUR:

105863490(MECR)

LCAT:

123634288(MECR)

PCOQ:

105811704(MECR)

OGA:	100945529(MECR)

MMU:	26922(Mecr)

MCAL:

110292800(Mecr)

MPAH:

110323410(Mecr)

RNO:	29470(Mecr)

MCOC:

116096739(Mecr)

ANU:	117708166(Mecr)

MUN:	110561781(Mecr)

CGE:	100767445(Mecr)

MAUA:

101842891(Mecr)

PROB:

127225449(Mecr)

PLEU:

114705648(Mecr)

MORG:

121448730(Mecr)

MFOT:

126507211

AAMP:

119817839(Mecr)

NGI:	103745905(Mecr)

HGL:	101724669(Mecr)

CPOC:

100715702(Mecr)

CCAN:

109682919(Mecr)

DORD:

105998351(Mecr)

DSP:	122115208(Mecr)

PLOP:

125354822(Mecr)

NCAR:

124967197

MMMA:

107142042(Mecr)

OCU:

100349933

OPI:	101524422(MECR)

TUP:	102467735(MECR)

GVR:	103587221(MECR)

CFA:	478159(MECR)

CLUD:

112659885(MECR)

VVP:	112931654(MECR)

VLG:	121496584(MECR)

NPO:	129513673(MECR)

AML:	100475522(MECR)

UMR:	103666470(MECR)

UAH:	113268395(MECR)

UAR:	123782207(MECR)

ELK:

111143426

LLV:

125099290

MPUF:

101671673(MECR)

MNP:	132001944(MECR)

MLK:	131810401(MECR)

NVS:	122899666(MECR)

ORO:	101379858(MECR)

EJU:	114217199(MECR)

ZCA:	113909554(MECR)

MLX:	118019781(MECR)

NSU:	110574830(MECR)

LWW:

102728384

FCA:	101092129(MECR)

PYU:	121024837(MECR)

PCOO:

112872192(MECR)

PBG:	122480197(MECR)

PVIV:

125173478(MECR)

LRUF:

124516156

PTG:	102969551(MECR)

PPAD:

109256753(MECR)

PUC:

125912865

AJU:

106970375

HHV:	120233014(MECR)

BTA:	353301(MECR)

BOM:	102270769(MECR)

BIU:	109572703(MECR)

BBUB:

102400498(MECR)

BBIS:

104981208(MECR)

CHX:	102174887(MECR)

OAS:	101121831(MECR)

BTAX:

128069946(MECR)

ODA:	120855138(MECR)

CCAD:

122426078(MECR)

MBEZ:

129537963(MECR)

SSC:	100515782(MECR)

CFR:	102521194(MECR)

CBAI:

105063405(MECR)

CDK:	105090392(MECR)

VPC:	102530923(MECR)

BACU:

103008492(MECR)

BMUS:

118885172(MECR)

LVE:	103086569(MECR)

OOR:	101281145(MECR)

DLE:	111163362(MECR)

PCAD:

102982102(MECR)

PSIU:

116740232(MECR)

NASI:

112414317(MECR)

ECB:	100070598(MECR)

EPZ:	103550935(MECR)

EAI:	106839135(MECR)

MYB:	102243661(MECR)

MYD:	102773407(MECR)

MMYO:

118675051(MECR)

MLF:	102420159(MECR)

MDT:	132231412(MECR)

PKL:	118724588(MECR)

EFUS:

103291863(MECR)

MNA:	107540367(MECR)

DRO:	112299288(MECR)

SHON:

118994563(MECR)

AJM:	119052221(MECR)

PDIC:

114497311(MECR)

PHAS:

123831821(MECR)

MMF:	118626512(MECR)

PPAM:

129069245(MECR)

HAI:	109392095(MECR)

RFQ:	117027429(MECR)

PALE:

102898478(MECR)

PGIG:

120599618(MECR)

PVP:	105290547(MECR)

RAY:	107503530(MECR)

MJV:	108402910(MECR)

TOD:	119237222(MECR)

SARA:

101538782(MECR)

SETR:

126011156(MECR)

LAV:	100654333(MECR)

TMU:

101352887

ETF:	101647424(MECR)

DNM:	101442435(MECR)

MDO:	100021687(MECR)

GAS:	123240411(MECR)

SHR:	100917241(MECR)

AFZ:

127555587

PCW:	110206189(MECR)

TVP:	118837683(MECR)

OAA:	100087829(MECR)

GGA:	419601(MECR)

PCOC:

116230054(MECR)

MGP:	100550872(MECR)

CJO:	107324010(MECR)

TPAI:

128088251(MECR)

LMUT:

125703779(MECR)

NMEL:

110387480(MECR)

APLA:

101794596(MECR)

ACYG:

106045154(MECR)

CATA:

118257281(MECR)

AFUL:

116498049(MECR)

TGU:	100230450(MECR)

LSR:	110469531(MECR)

SCAN:

103822553(MECR)

PMOA:

120511742(MECR)

OTC:	121333599(MECR)

PRUF:

121359999(MECR)

GFR:	102036101(MECR)

FAB:	101807719(MECR)

OMA:	130262098(MECR)

PHI:	102104482(MECR)

PMAJ:

107214176(MECR)

CCAE:

111939046(MECR)

CCW:	104697704(MECR)

CBRC:

103619531(MECR)

ETL:	114069774(MECR)

ZAB:	102062380(MECR)

ZLE:	135457264(MECR)

ACHL:

103797397(MECR)

SVG:	106859998(MECR)

MMEA:

130581218(MECR)

HRT:	120763228(MECR)

SATI:

136371179(MECR)

FPG:	101914759(MECR)

FCH:	102059889(MECR)

CCRI:

104161509(MECR)

NNT:	104411267(MECR)

SHAB:

115615904(MECR)

ACUN:

113488360(MECR)

TALA:

104360966(MECR)

ACHC:

115352077(MECR)

HALD:

104319599(MECR)

HLE:	104837224(MECR)

AGEN:

126046844

GCL:

127025072

CSTI:

104556014(MECR)

LDI:	104347176(MECR)

MNB:	103771676(MECR)

DPUB:

104309302(MECR)

AVIT:

104279573(MECR)

BRHI:

104490730(MECR)

EGZ:	104132529(MECR)

NNI:	104017818(MECR)

PCRI:

104030326(MECR)

PCAO:

104046341(MECR)

PADL:

103915440(MECR)

AFOR:

103906404(MECR)

FGA:	104083553(MECR)

GSTE:

104260138(MECR)

CLV:	102096502(MECR)

MUI:	104533650(MECR)

PGUU:

104457724(MECR)

PLET:

104615200(MECR)

EHS:	104511893(MECR)

CMAC:

104473218(MECR)

CUCA:

104059518(MECR)

TEO:	104374308(MECR)

BREG:

104634361(MECR)

OHA:	104334247(MECR)

ACAR:

104528728(MECR)

CPEA:

104398216(MECR)

CVF:	104289399(MECR)

RTD:	128918982(MECR)

AAM:	106494805(MECR)

AROW:

112971198(MECR)

NPD:	112950943(MECR)

TGT:	104572223(MECR)

DNE:	112981218(MECR)

SCAM:

104139567(MECR)

ASN:	102369038(MECR)

AMJ:	102561710(MECR)

CPOO:

109318418(MECR)

GGN:	109293986(MECR)

PSS:	102462953(MECR)

CMY:	102931172(MECR)

CCAY:

125624600(MECR)

DCC:	119845459(MECR)

CPIC:

101948358(MECR)

TST:	117868282(MECR)

CABI:

116837927(MECR)

MRV:	120389309(MECR)

ACS:	100559419(mecr)

ASAO:

132780839(MECR)

PVT:	110082281(MECR)

SUND:

121915482(MECR)

PBI:	103065964(MECR)

PMUR:

107286036(MECR)

CTIG:

120304143(MECR)

TSR:	106553700(MECR)

PGUT:

117663467(MECR)

APRI:

131204656(MECR)

PTEX:

113437471(MECR)

VKO:	123026038(MECR)

PMUA:

114603627(MECR)

PRAF:

128418637(MECR)

ZVI:	118087529(MECR)

HCG:	128332593(MECR)

GJA:	107121096(MECR)

STOW:

125435677(MECR)

EMC:	129343518(MECR)

XLA:	100380999(mecr.S) 108708222(mecr.L) 108716757(XB5816429.L)

XTR:	100170432 549125(mecr)

NPR:	108786893 108792955(MECR)

RTEM:

120926943(MECR) 120937308

BBUF:

120995265(MECR) 120997068

BGAR:

122933094(MECR) 122934432

MUO:	115464301 115464858 115480632 115481016

GSH:	117357258 117365317(MECR)

DRE:	101884755 550550(mecr)

SRX:	107711618 107732725 107744600

SANH:

107653147 107689006 107703920(mecr)

SGH:	107560497 107598945

CCAR:

109058225 109106675

CAUA:

113059816(mecr) 113063450

CGIB:

127938215 128031228

PTET:

122324472 122360572(mecr)

LROH:

127178456(mecr) 127182907

OMC:	131522487(mecr)

PPRM:

120468704(mecr) 120486940

RKG:	130090195 130096584(mecr)

MAMB:

125243629(mecr) 125278842

CIDE:

127497222 127502986

CERY:

137019468 137029937(mecr)

MASI:

127409923 127415854 127452634 127454407

TROS:

130558659(mecr) 130566256

TDW:	130433399(mecr) 130434642

MANU:

129448018(mecr)

IPU:

108271049

IFU:	128612044(mecr)

PHYP:

113534213(mecr)

SMEO:

124383770(mecr)

TFD:	113644854(mecr)

TVC:	132845764(mecr)

TRN:	134310556(mecr) 134319829

AMEX:

103027603(mecr) 103046320

CMAO:

118816221 118818985(mecr)

EEE:	113567799 113578062

CHAR:

105901194 105910050(mecr)

TRU:	101075341(mecr)

TFS:	130532484(mecr)

TNG:	GSTEN00009565G001

LCO:	104919565(mecr)

NCC:	104965874(mecr)

TBEN:

117468474 117468475(mecr)

CGOB:

115020838(mecr)

PGEO:

117461197(mecr)

GACU:

117557469(mecr)

EMAC:

134861443(mecr)

ELY:	117265810(mecr)

EFO:	125893589(mecr)

PLEP:

121945164(mecr)

SLUC:

116042962(mecr)

ECRA:

117946820(mecr)

ESP:	116691727(mecr)

PFLV:

114556877(mecr)

GAT:	120810148(mecr)

PPUG:

119197899(mecr)

AFB:	129109080(mecr)

CLUM:

117745704(mecr)

PSWI:

130212883(mecr)

MSAM:

119897302(mecr)

SCHU:

122881044(mecr)

CUD:	121514009(mecr)

ALAT:

119005430(mecr)

MZE:	101474487(mecr)

ONL:	100692276(mecr)

OAU:	116320946(mecr)

OLA:	101166333(mecr)

OML:	112144120(mecr)

CSAI:

133441081(mecr)

XMA:	102230177(mecr)

XCO:	114139554(mecr)

XHE:	116717333(mecr)

PRET:

103477824(mecr)

PFOR:

103141562(mecr)

PLAI:

106948824(mecr)

PMEI:

106907299(mecr)

GAF:	122831659(mecr)

PPRL:

129370898(mecr)

CVG:	107084704(mecr)

CTUL:

119797867(mecr)

GMU:	124865310(mecr)

NFU:	107379372(mecr)

KMR:	108235538(mecr)

ALIM:

106526606(mecr)

NWH:	119409939(mecr)

AOCE:

111563376(mecr)

MCEP:

125016150(mecR)

CSEM:

103387891(mecr)

POV:	109633133(mecr)

SSEN:

122774710(mecr)

HHIP:

117776536(mecr)

HSP:	118114100(mecr)

PPLT:

128449185(mecr)

SMAU:

118299996(mecr)

LCF:

108898671

SDU:	111235799(mecr)

SLAL:

111651139(mecr)

XGL:	120783876(mecr)

HCQ:	109513103(mecr)

SSCV:

125974673

SBIA:

133501279(mecr)

PEE:	133401314(mecr)

PTAO:

133479556(mecr)

BPEC:

110174366(mecr)

MALB:

109954672(mecr)

BSPL:

114843262(mecr)

SJO:	128367135(mecr)

SASA:

106581738 106605110(mecr) 106607757

STRU:

115176641(mecr) 115193781

OTW:	112217559 112223100

OMY:	110489198 110522173

OGO:	123995038 123997577

ONE:	115139472 115141233(mecr)

OKI:	109866724 109902166(mecr)

OKE:	118364260 118367335(mecr) 118386838

SALP:

111965212(mecr) 111973052

SNH:	120019692 120048315

CCLU:

121549160 121561840 121562368

ELS:	105017915 105027165(mecr)

SFM:	108927588(mecr)

PKI:	111836167 111848856(mecr)

AANG:

118225610(mecr) 118230390

LOC:	102686596 102687891(mecr)

PSPA:

121308206(mecr)

ARUT:

117412763(mecr)

PSEX:

120525300

LCM:	102354084 102367609(MECR)

CMK:	103179492(mecr)

RTP:	109937993(mecr)

CPLA:

122563514(mecr)

HOC:

132829885

LERI:

129709888(mecr)

PMRN:

116938974(MECR) 116953000

LRJ:	133347599 133348641(MECR)

BFO:

118411089

BBEL:

109468479

SPU:	105440644 574708

LPIC:

APLC:

ARUN:

AJC:

SKO:	100371192 102803511

DME:	Dmel_CG16935(CG16935)

DER:

6549270

DSE:

6609062

DSI:	Dsimw501_GD25735(Dsim_GD25735)

DYA:	Dyak_GE13334

DAN:

DSR:

DPO:

DPE:

DMN:	108159140 117193641

DWI:	6640604 6641085

DGR:

6560484

DMO:	Dmoj_GI20971

DNV:

DHE:

DVI:

CCAT:

BOD:	106620210 106622860

BDR:	105232829 109579388

RZE:	108371554 108372447 108373403 108375273

AOQ:	129242363 129246436

TDA:

119677430

MDE:

101901436

SCAC:

106081242

LCQ:	111680302 111680313

LSQ:	119613121 119613131

GFS:	119635774 119644491 119644499

ECOE:

CLON:

HIS:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AFUN:

AMOU:

AALI:

AAG:

AALB:

109402270 115257450 115257894

ASUA:

134221935

CQU:	CpipJ_CPIJ006453 CpipJ_CPIJ014619

CPII:

CNS:

BCOO:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

DQU:

CFO:

FEX:

LHU:

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

TPRE:

LHT:

LBD:

MDL:

CGLO:

FAS:	105263151 105273006

DAM:

AGIF:

CINS:

VCAN:

CCIN:

DSM:

NPT:

NFB:

NLO:

NVG:

AROA:

TCA:

DPA:

SOY:

AGRG:

ATD:

CSET:

AGB:	108905168 108905214

LDC:	111511798 111513097 111513098

DVV:	114326242 114327373 114334614

NVL:

108558105

APLN:

108735774 108735778 112906697

PPYR:

OTU:

BMOR:

BMAN:

MSEX:

DPL:	KGM_216075

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

PRAP:

PBX:

PNAP:

ZCE:

CCRC:

LSIN:

HAW:

HZE:	124638778 124639023

TNL:

SLIU:

OFU:

ATRA:

GMW:

PXY:

PGW:

LGLY:

CFEL:

CCRN:

API:

DNX:

AGS:

RMD:

ACOO:

DVT:

BTAB:

DCI:

CLEC:

HHAL:

NLU:

HVI:

MQU:	128990210 128990268 129005947

PHU:	Phum_PHUM127430

FOC:

TPAL:

ZNE:

CSEC:

SGRE:

BROR:

IEL:

FCD:

DPX:	DAPPUDRAFT_306158

DMK:

DPZ:

PVM:

PJA:

PCHN:

HAME:

PCLA:

CQD:

PTRU:

ESN:

HAZT:

EAF:

LSM:

TCF:

PPOI:

DSV:

RSAN:

RMP:

VDE:

VJA:

TUT:	107361729 107361992

DPTE:

DFR:

CSCU:

CVS:

PTEP:

ABRU:

UDV:

SDM:

LPOL:

PMEO:

CEL:	CELE_W09H1.5(mecr-1) CELE_Y48A6B.9(Y48A6B.9)

CBR:	CBG_02813 CBG_02814(Cbr-mecr-1) CBG_18225

CRQ:	GCK72_005275 GCK72_005301 GCK72_010324 GCK72_012266

NAI:	NECAME_02958

BMY:	BM_BM13654(Bm13654)

LOA:	LOAG_09612

TSP:	Tsp_03549 Tsp_07030

HRO:	HELRODRAFT_170854

LGI:	LOTGIDRAFT_119678

PVUL:

PCAN:

BGT:

GAE:

HRF:

HRJ:

CRG:

CANU:

CVN:

OED:

MYI:

PMAX:

MCAF:

MMER:

RPHI:

DPOL:

MAEA:

OBI:

OSN:	115223323 115227881 115230691 115230697

LJP:

135461351

LAK:	106153891 106177876

SMM:	Smp_026310

SHX:	MS3_00005326

OVI:	T265_13032

EGL:

LLON:

NVE:

EPA:

ATEN:

ADF:

AMIL:

PDAM:

SPIS:

DGT:

XEN:	124435138 124435159 124451971

AQU:

ATH:

ALY:

CRB:

CSAT:

104711035 104783816 104790814 109124554

EUS:	EUTSA_v10002573mg EUTSA_v10025585mg

BRP:

103873568

BNA:	106376429 106402450

BOE:

RSZ:

THJ:

CPAP:

CIT:

CIC:	CICLE_v10028610mg

PVY:	116109496 116121715

MINC:

123225720

TCC:

18590821

GRA:

105788920

GHI:	107950314 121224237

GAB:

108461808

HSYR:

120160066

DZI:

111285194

EGR:	104432824 104445446 120286245

GMX:

100810089

GSJ:

114372882

PVU:	PHAVU_005G138600g

VRA:

VAR:

VUN:

VUM:

CCAJ:

APRC:

MTR:

TPRA:

CAM:

PSAT:

VVO:	131621443 131621444 131653863 131653864 131653865

LJA:

130743257

ADU:

107461660

AIP:

107614128

AHF:	112706748 112771420

LANG:

109351050

PCIN:

129314944

QSA:	O6P43_028314

FVE:

RCN:

PPER:

PMUM:

PAVI:

PDUL:

MDM:

MSYL:

PXB:	103942650 103948912

ZJU:

MNT:

CSAV:

CSV:

CMO:

BHJ:

MCHA:

CMAX:

CMOS:

CPEP:

RCU:

MEAN:

JCU:

HBR:

MESC:

POP:

PEU:

PALZ:

JRE:

CILL:

CAVE:

QSU:

QLO:

TWL:

VVI:

VRI:

SLY:	101247598 101253659 101253969

SPEN:

107002927 107004307 107005794

SOT:	102596064 102599768 102601699 102605504

SSTN:

125844435 125845084 125849945 125849947 125850848

SDUL:

129902118 129903917 129904362

CANN:

107846861 107848020 107848301 107848302

LBB:	132599529 132599572 132600822 132600823

NTA:	107764114 107769029 107769030 107796853 107828176

NSY:	104212083 104212084 104219373 104222093

NTO:	104110007 104112573 104112574

NAU:	109235173 109235174 109235821

INI:

ITR:

SIND:

OEU:

EGT:

SSPL:

SHIS:

APAN:

HAN:	110865218 110939958 118479250

ECAD:

122592726

LSV:

111886574

CCAV:

112506962

DCR:	108208087 108208867

CSIN:

RVL:

AEW:

BVG:

SOE:

CQI:	110684193 110684675

ATRI:

MOF:

NNU:

MING:

TSS:

PSOM:

113307683 113321973 113361017

OSA:	4351241 9272332

OBR:

102703069

OGL:	127754412 127757241

BDI:	100829535 100843602

ATS:

109763440

TDC:	119301042 119308559

TAES:

123103253 123111443 123124628

TUA:	125508786 125508791

LPER:

127298412 127300214

LRD:	124653129 124653287 124656488 124657595

SBI:

8086052

ZMA:

100501714

MFLO:

136471846 136476337 136501743

SITA:

101781160 101781841

SVS:	117863613 117867017

PVIR:

PHAI:

PDA:

EGU:

MUS:

ZOF:	121976478 122015615 122035482

DCT:

PEQ:

AOF:

MSIN:

NCOL:

ATR:	18423619 18423626 18423627

SMO:	SELMODRAFT_233661 SELMODRAFT_438497 SELMODRAFT_74091 SELMODRAFT_92070

PPP:	112274334 112287087

CRE:	CHLRE_01g035350v5

MNG:	MNEG_13625

CSL:	COCSUDRAFT_30456

CVR:	CHLNCDRAFT_27061

APRO:

F751_3032 F751_6882

OLU:	OSTLU_45262 OSTLU_4811

OTA:	OT_ostta03g01370 OT_ostta17g00300

BPG:	Bathy06g01630

MIS:	MICPUN_102855 MICPUN_57731

MPP:	MICPUCDRAFT_4292 MICPUCDRAFT_4722

CME:	CYME_CMO278C

GSL:	Gasu_34350

CCP:	CHC_T00008594001

SCE:	YBR026C(ETR1)

SEUB:

DI49_0205

SPAO:

SPAR_B01300

AGO:	AGOS_AEL081W

ERC:

Ecym_3544

KLA:	KLLA0_F24552g

KMX:	KLMA_60271(ETR1)

LTH:	KLTH0C09020g

VPO:	Kpol_1036p36

ZRO:	ZYRO0A03916g

CGR:	2886666(GVI51_B04257)

NCS:	NCAS_0A10280(NCAS0A10280)

NDI:	NDAI_0A07200(NDAI0A07200)

TPF:	TPHA_0M00590(TPHA0M00590)

TBL:	TBLA_0G02880(TBLA0G02880)

TGB:	HG536_0G03280

TDL:	TDEL_0D03960(TDEL0D03960)

KAF:	KAFR_0F02350(KAFR0F02350)

KNG:	KNAG_0K01630(KNAG0K01630)

ZMK:	HG535_0C02100

SLUD:

SCDLUD_002402

DHA:	DEHA2C05808g DEHA2F10362g

PIC:	PICST_34892(ETR2) PICST_53084(ETR1)

PGU:	PGUG_01862 PGUG_05322

SPAA:

SPAPADRAFT_61753 SPAPADRAFT_61769

LEL:	PVL30_000344(ETR1_1) PVL30_002296(ETR1_2)

LBG:	92205934(LODBEIA_P07380) 92207343(LODBEIA_P21470)

CAL:	CAALFM_C111700CA(MRF1) CAALFM_C300200CA(ETR1)

CTP:	CTRG_03474 CTRG_06166

COT:	CORT_0A04550 CORT_0D07560

CDU:	CD36_11010 CD36_80180

CTEN:

18250796(ETR1)

CLU:	CLUG_00888

CLUS:

A9F13_10g01672

CAUR:

CJI96_0003817

PPA:	PAS_chr4_0311

PKZ:	C5L36_0B10340

BNN:	FOA43_003927

BBRX:

BRETT_000650

OPA:	HPODL_02149

YLI:	2909944(YALI2_B00429g)

SLB:	AWJ20_1693(ETR1)

NCR:

NCU00655

SMP:	10810132(SMAC4_01336)

PAN:	PODANSg4501 PODANSg8628

PBEL:

QC761_120040(ETR1)

PPSD:

QC762_120040(ETR1)

PPSP:

QC763_120040(ETR1)

PPSA:

QC764_120040(ETR1)

TTT:	THITE_2111907

MTM:	MYCTH_39983

CTHR:

MGR:

PPEI:

PGRI:

TMN:	UCRPA7_4880

SSCK:

SPSK_06296

FGR:	FGSG_08521

FPU:	FPSE_10171

FPOA:

FPOAC1_004630

FVN:	FVRRES_05129

FVR:	FVEG_02193 FVEG_09866

FOX:	FOXG_03323 FOXG_10934

NHE:	NECHADRAFT_99584

FFC:	NCS54_00399800

FMU:	J7337_008537

TRE:	TRIREDRAFT_66960

TRR:	M419DRAFT_86973

TATV:

25786226(TrAtP1_012567)

TASP:

36608429(TrAFT101_010169)

MAW:	19245134(ETR1)

MAJ:

MAA_07416

MBRN:

26245273(ETR1)

PCHM:

VFPPC_13681

CMT:

CCM_03363

AMUS:

LMH87_002240

PLJ:	28882411(PLICBS_001554)

PTKZ:

JDV02_009895(ETR1)

VDA:	VDAG_01873

CFJ:	CFIO01_07523

CLUP:

CLUP02_08537

CHIG:

CH63R_07598

SAPO:

SAPIO_CDS9890

ELA:	UCREL1_7638

PFY:	PFICI_03016

SSL:	SS1G_11336

BFU:	BCIN_08g04480(Bcetr1)

MBE:

MBM_07542

PSCO:

LY89DRAFT_657507

GLZ:	GLAREA_10755

ANI:	ANIA_09401

AFM:	AFUA_3G04150

ACT:	ACLA_060640

NFI:	NFIA_006420

AOR:	AO090124000077

ANG:	An01g00120

AFV:	AFLA_009134

ALUC:

AKAW2_20209A(ETR1)

ACHE:

ACHE_40279A(ETR1)

APUU:

APUU_50283S(ETR1)

PCS:	N7525_000065

PDP:	PDIP_67860

POU:	POX_g09195

TMF:	EYB26_009154

TRG:	TRUGW13939_07295

CIM:	CIMG_08466

CPW:	CPC735_061360

URE:	UREG_02545

ABE:

ARB_06054

TVE:

TRV_08128

PBL:	PAAG_01536 PAAG_07697

PBN:	PADG_00244 PADG_02837

AJE:	HCAG_01842 HCAG_07622

BGH:	BDBG_00201 BDBG_09200

PNO:	SNOG_02540

PTE:

PTT_19942

PTRR:

6346770(PtrM4_147380)

BZE:	COCCADRAFT_2010

BSC:	COCSADRAFT_236653

BOR:	COCMIDRAFT_82460

AALT:

CC77DRAFT_982294

ARAB:

EKO05_0004650

ZTR:	MYCGRDRAFT_84372

PFJ:	MYCFIDRAFT_211068 MYCFIDRAFT_46226

FFU:	CLAFUR5_10233

CBET:

CB0940_06410

BCOM:

BAUCODRAFT_151162

NPA:	UCRNP2_5177

TML:	GSTUM_00004457001

SPO:	2542100(etr1)

SOM:	SOMG_03972(etr1)

TVS:	TRAVEDRAFT_124364

DSQ:	DICSQDRAFT_53580

PCO:	PHACADRAFT_263603

SHS:	STEHIDRAFT_57652

HIR:	HETIRDRAFT_323520

PSQ:	PUNSTDRAFT_106208

FME:	FOMMEDRAFT_144375

GTR:	GLOTRDRAFT_139929

RSX:	RhiXN_05034

LBC:	LACBIDRAFT_229832

CCI:	CC1G_14862

MRR:	Moror_10464

E1B28_005987 E1B28_005989

SCM:	SCHCO_02626208(SCHCODRAFT_02626208)

SLA:	SERLADRAFT_472718

WSE:	WALSEDRAFT_52591

WIC:	J056_001020

PGR:	PGTG_02130

PTRC:

PtA15_2A735

PSTR:

Pst134EA_005255

MLR:	MELLADRAFT_89254

RIE:	OCT59_016605

MBR:	MONBRDRAFT_1704

SRE:	PTSG_01560

DDI:	DDB_G0278095(mecr)

DPP:	DICPUDRAFT_50320

DFA:	DFA_03242(mecr)

ACAN:

ACA1_070350

TET:	TTHERM_00298379

PTI:	PHATR_10497

AAF:	AURANDRAFT_65428

PIF:	PITG_15045

PSOJ:

PHYSODRAFT_545994

SPAR:

SPRG_15716

GTT:	GUITHDRAFT_160291

NGR:	NAEGRDRAFT_58740

ZAL:	AZF00_03215

MICC:

AUP74_02356(qorA_2)

MII:	BTJ40_13635

MICT:

FIU95_11750(mas)

AMU:

Amuc_1190

AGL:

PYTT_1108

ROO:	G5S37_20485

LUO:	HHL09_11985

» show all

Reference

PMID:12654921

Authors

Miinalainen IJ, Chen ZJ, Torkko JM, Pirila PL, Sormunen RT, Bergmann U, Qin YM, Hiltunen JK

Title

Characterization of 2-enoyl thioester reductase from mammals. An ortholog of YBR026p/MRF1'p of the yeast mitochondrial fatty acid synthesis type II.

Journal

J Biol Chem 278:20154-61 (2003)
DOI:10.1074/jbc.M302851200

Reference

PMID:11509667

Authors

Torkko JM, Koivuranta KT, Miinalainen IJ, Yagi AI, Schmitz W, Kastaniotis AJ, Airenne TT, Gurvitz A, Hiltunen KJ

Title

Candida tropicalis Etr1p and Saccharomyces cerevisiae Ybr026p (Mrf1'p), 2-enoyl thioester reductases essential for mitochondrial respiratory competence.

Journal

Mol Cell Biol 21:6243-53 (2001)
DOI:10.1128/MCB.21.18.6243-6253.2001

Sequence

[sce:YBR026C]

LinkDB

REACTION: R01404

Entry

R01404                      Reaction

Name

acyl-[acyl-carrier protein]:NADP+ oxidoreductase

Definition

Acyl-[acyl-carrier protein] + NADP+ <=> trans-2,3-Dehydroacyl-[acyl-carrier protein] + NADPH + H+

Equation

C00173 + C00006 <=> C00693 + C00005 + C00080

Reaction class

RC00001

C00005_C00006

RC00120

C00173_C00693

Enzyme

1.3.1.10 1.3.1.39 1.3.1.104 1.3.1.-

Pathway

rn00061

Fatty acid biosynthesis

rn01100

Metabolic pathways

Brite

Enzymatic reactions [BR:br08201]
1. Oxidoreductase reactions
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.10
     R01404  Acyl-[acyl-carrier protein] + NADP+ <=> trans-2,3-Dehydroacyl-[acyl-carrier protein] + NADPH + H+
    1.3.1.39
     R01404  Acyl-[acyl-carrier protein] + NADP+ <=> trans-2,3-Dehydroacyl-[acyl-carrier protein] + NADPH + H+
    1.3.1.104
     R01404  Acyl-[acyl-carrier protein] + NADP+ <=> trans-2,3-Dehydroacyl-[acyl-carrier protein] + NADPH + H+
    1.3.1.-
     R01404  Acyl-[acyl-carrier protein] + NADP+ <=> trans-2,3-Dehydroacyl-[acyl-carrier protein] + NADPH + H+
IUBMB reaction hierarchy [BR:br08202]
1. Oxidoreductase reactions
  1.3.1.10
   R01404  Acyl-[acyl-carrier protein] <=> trans-2,3-Dehydroacyl-[acyl-carrier protein]
  1.3.1.39
   R01404  Acyl-[acyl-carrier protein] <=> trans-2,3-Dehydroacyl-[acyl-carrier protein]
  1.3.1.104
   R01404  Acyl-[acyl-carrier protein] <=> trans-2,3-Dehydroacyl-[acyl-carrier protein]

Orthology

K00208

enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10]

K00665

fatty acid synthase, animal type [EC:2.3.1.85]

K00668

fatty acid synthase subunit beta, fungi type [EC:2.3.1.86]

K07512

mitochondrial enoyl-[acyl-carrier protein] reductase / trans-2-enoyl-CoA reductase [EC:1.3.1.- 1.3.1.38]

K10780

enoyl-[acyl-carrier protein] reductase III [EC:1.3.1.104]

Other DBs

RHEA:

22567

LinkDB

DBGET integrated database retrieval system