Contains a tightly-bound FAD cofactor. Unlike other acyl-CoA dehydrogenases, this enzyme exhibits high substrate- and enantiomer specificity; it is highly specific for (R)-benzylsuccinyl-CoA and is inhibited by (S)-benzylsuccinyl-CoA. Forms the third step in the anaerobic toluene metabolic pathway in Thauera aromatica. Ferricenium ion is an effective artificial electron acceptor.
EC 184.108.40.206 created 2003 as EC 220.127.116.11, transferred 2012 to EC 18.104.22.168
Enzymatic reactions [BR:br08201]
1. Oxidoreductase reactions
1.3 Acting on the CH-CH group of donors
1.3.8 With a flavin as acceptor
R05584 Benzylsuccinyl-CoA + 2 Electron-transferring flavoprotein <=> E-Phenylitaconyl-CoA + 2 Reduced electron-transferring flavoprotein