KEGG   ORTHOLOGY: K07964
Entry
K07964                      KO                                     
Symbol
HPSE
Name
heparanase [EC:3.2.1.166]
Pathway
map00531  Glycosaminoglycan degradation
map01100  Metabolic pathways
map05205  Proteoglycans in cancer
Module
M00078  Heparan sulfate degradation
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00531 Glycosaminoglycan degradation
    K07964  HPSE; heparanase
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    K07964  HPSE; heparanase
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   00536 Glycosaminoglycan binding proteins
    K07964  HPSE; heparanase
Enzymes [BR:ko01000]
 3. Hydrolases
  3.2  Glycosylases
   3.2.1  Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
    3.2.1.166  heparanase
     K07964  HPSE; heparanase
Glycosaminoglycan binding proteins [BR:ko00536]
 Heparan sulfate / Heparin
  Enzymes
   K07964  HPSE; heparanase
Other DBs
RN: R07811
GO: 0030305
CAZy: GH79
Genes
HSA: 10855(HPSE)
PTR: 461206(HPSE)
PPS: 100996218(HPSE)
GGO: 101150800(HPSE)
PON: 100448281(HPSE)
NLE: 100596185(HPSE)
MCC: 707583(HPSE)
MCF: 102123028(HPSE)
CSAB: 103235901(HPSE)
CATY: 105576795(HPSE)
PANU: 101008008(HPSE)
TGE: 112624635(HPSE)
RRO: 104658833(HPSE)
RBB: 108531149(HPSE)
TFN: 117085378(HPSE)
PTEH: 111549300(HPSE)
CJC: 100402671(HPSE)
SBQ: 101043067(HPSE)
CSYR: 103265158(HPSE)
MMUR: 105872605(HPSE)
OGA: 100965397(HPSE)
MMU: 15442(Hpse)
MCAL: 110294241(Hpse)
MPAH: 110330557(Hpse)
RNO: 64537(Hpse)
MCOC: 116067960(Hpse)
MUN: 110553884(Hpse)
CGE: 100755610(Hpse)
PLEU: 114691766(Hpse)
NGI: 103744984(Hpse)
HGL: 101721140(Hpse)
CPOC: 100721886(Hpse)
CCAN: 109683307(Hpse)
DORD: 105988588(Hpse)
DSP: 122097868(Hpse)
OCU: 100101601(HPSE)
OPI: 101525206(HPSE)
TUP: 102501533(HPSE)
CFA: 608707(HPSE)
VVP: 112919568(HPSE)
VLG: 121493930(HPSE)
AML: 100470911(HPSE)
UMR: 103665420(HPSE)
UAH: 113263199(HPSE)
UAR: 123787859(HPSE)
ELK: 111149020
MPUF: 101688281(HPSE)
ORO: 101371822(HPSE)
EJU: 114224914(HPSE)
ZCA: 113925912(HPSE)
MLX: 118010381(HPSE)
FCA: 101090101(HPSE)
PYU: 121033261(HPSE)
PBG: 122478708(HPSE)
PTG: 102965445(HPSE)
PPAD: 109276572(HPSE)
AJU: 106987077(HPSE)
HHV: 120246450(HPSE)
BTA: 281230(HPSE)
BOM: 102265641(HPSE)
BIU: 109560640(HPSE)
BBUB: 102395500(HPSE)
CHX: 102188207(HPSE)
OAS: 101118612(HPSE)
ODA: 120861521(HPSE)
CCAD: 122428283(HPSE)
SSC: 100271932(HPSE)
CFR: 102517816(HPSE)
CBAI: 105065287(HPSE)
CDK: 105092018(HPSE)
BACU: 102999760(HPSE)
LVE: 103084178(HPSE)
OOR: 101283118(HPSE)
DLE: 111187577(HPSE)
PCAD: 102985869(HPSE)
PSIU: 116754204(HPSE)
ECB: 100061267(HPSE)
EPZ: 103549090(HPSE)
EAI: 106846420(HPSE)
MYB: 102245458(HPSE)
MYD: 102774009(HPSE)
MMYO: 118670781(HPSE)
MLF: 102436832(HPSE)
MNA: 107537105(HPSE)
PKL: 118704413(HPSE)
HAI: 109387924(HPSE)
DRO: 112317780(HPSE)
SHON: 118979540(HPSE)
AJM: 119054621(HPSE)
PDIC: 114492003(HPSE)
PHAS: 123806934(HPSE)
MMF: 118640491(HPSE)
RFQ: 117022519(HPSE)
PALE: 102888805(HPSE)
PGIG: 120588285(HPSE)
PVP: 105289595(HPSE)
RAY: 107516475(HPSE)
MJV: 108394108(HPSE)
TOD: 119260898(HPSE)
LAV: 100676520(HPSE)
TMU: 101360212
DNM: 101444076(HPSE)
MDO: 100026183(HPSE)
GAS: 123251465(HPSE)
SHR: 100923804(HPSE)
PCW: 110209762(HPSE)
GGA: 373981(HPSE)
PCOC: 116231114(HPSE)
MGP: 100545679(HPSE)
CJO: 107313425(HPSE)
NMEL: 110399069(HPSE)
APLA: 101797825(HPSE)
ACYG: 106041934(HPSE)
AFUL: 116489002(HPSE)
TGU: 100218163(HPSE)
LSR: 110468522(HPSE)
SCAN: 103826088(HPSE)
PMOA: 120496083(HPSE)
OTC: 121339835(HPSE)
PRUF: 121360463(HPSE)
GFR: 102040930(HPSE)
FAB: 101809526(HPSE)
PHI: 102109966(HPSE)
PMAJ: 107203573(HPSE)
CCAE: 111928869(HPSE)
CCW: 104697252(HPSE)
ETL: 114057759(HPSE)
ZAB: 102062765(HPSE)
FPG: 101912317(HPSE)
FCH: 102057366(HPSE)
CLV: 102085346(HPSE)
EGZ: 104127343(HPSE)
NNI: 104014988(HPSE)
ACUN: 113479584(HPSE)
TALA: 104365048(HPSE)
PADL: 103919913(HPSE)
ACHC: 115338962(HPSE)
AAM: 106494822(HPSE)
AROW: 112970688(HPSE)
NPD: 112951906(HPSE)
DNE: 112990443(HPSE)
ASN: 102369021
AMJ: 102571669(HPSE)
CPOO: 109321870(HPSE)
GGN: 109303678(HPSE)
PSS: 102450514(HPSE)
CMY: 102946031(HPSE)
CPIC: 101942907(HPSE)
TST: 117878215(HPSE)
CABI: 116836664(HPSE)
MRV: 120406245(HPSE)
ACS: 100565376(hpse)
PVT: 110083349(HPSE)
SUND: 121932136(HPSE)
PBI: 103050955(HPSE)
PMUR: 107303159(HPSE)
PGUT: 117673663(HPSE)
VKO: 123022631(HPSE)
PMUA: 114604526(HPSE)
ZVI: 118083498(HPSE)
GJA: 107116059(HPSE)
XLA: 108719705(hpse.L)
XTR: 100145320(hpse)
NPR: 108804446(HPSE)
RTEM: 120915912(HPSE)
BBUF: 120989721(HPSE)
BGAR: 122945288(HPSE)
DRE: 563020(hpse)
SRX: 107722827(hpse)
SANH: 107681091(hpse) 107703469
SGH: 107589237(hpse) 107591750
IPU: 108278991(hpse)
PHYP: 113543026(hpse)
SMEO: 124398473(hpse)
AMEX: 103027675(hpse)
EEE: 113570752(hpse)
TRU: 101076415(hpse)
LCO: 104939605(hpse)
NCC: 104957343
CGOB: 115005073(hpse)
ELY: 117270168(hpse)
PLEP: 121959693(hpse)
SLUC: 116041823(hpse)
PFLV: 114571209(hpse)
PPUG: 119227058(hpse)
MSAM: 119914560(hpse)
CUD: 121524728(hpse)
MZE: 101471023(hpse)
ONL: 100704102(hpse)
OAU: 116321504(hpse)
OLA: 101156941(hpse)
OML: 112162914(hpse)
XMA: 102231016(hpse)
XCO: 114150028(hpse)
XHE: 116724936(hpse)
PRET: 103473150(hpse)
PFOR: 103152308(hpse)
PLAI: 106947039(hpse)
PMEI: 106904036(hpse)
GAF: 122819209(hpse)
CVG: 107100851(hpse)
CTUL: 119797736(hpse)
NFU: 107390264(hpse)
KMR: 108242518(hpse)
ALIM: 106524410(hpse)
NWH: 119425089(hpse)
CSEM: 103390393(hpse)
POV: 109648055
SSEN: 122787041(hpse)
HHIP: 117771320(hpse)
LCF: 108892286(hpse)
SDU: 111238027(hpse)
XGL: 120806035(hpse)
HCQ: 109517543(hpse)
BPEC: 110161656(hpse)
SASA: 106563622(hpse) 106568158
OTW: 112219520(hpse)
OMY: 110523793(hpse)
OGO: 124048738(hpse)
SNH: 120026458(hpse) 120044991
ELS: 105014724(hpse)
SFM: 108935179(hpse)
PKI: 111842231(hpse)
AANG: 118212115(hpse)
LOC: 102686050(hpse)
PSPA: 121303644(hpse)
LCM: 102346905(HPSE)
CMK: 103187960(hpse)
RTP: 109935286(hpse)
BFO: 118413989
BBEL: 109471425
AME: 725623
ACER: 107996324
ALAB: 122712848
BIM: 100745198
BBIF: 117209398
BVK: 117240191
BVAN: 117164389
BTER: 105666557
BPYO: 122575821
CCAL: 108630640
OBB: 114877484
MGEN: 117218147
NMEA: 116431518
CGIG: 122405059
SOC: 105193112
MPHA: 105836142
AEC: 105154939
ACEP: 105626290
PBAR: 105430094
VEM: 105559915
HST: 105180876
DQU: 106751247
CFO: 105248467
FEX: 115237339
LHU: 105671110
PGC: 109853681
OBO: 105281678
PCF: 106786988
PFUC: 122515261
VPS: 122636119
NVI: 100113700
CSOL: 105368274
TPRE: 106659608
MDL: 103580115
CGLO: 123271325
FAS: 105263758
DAM: 107038411
CCIN: 107263116
TCA: 659639
SOY: 115874561
ATD: 109608715
CSET: 123310036
AGB: 108905388
LDC: 111502285
NVL: 108564172
OTU: 111415667
BMOR: 100141461(Hepa) 101744388
MSEX: 115451084
BANY: 112042805
PPOT: 106104492
PRAP: 110998158
ZCE: 119835673
HAW: 110374496
TNL: 113506141
OFU: 114359330
AGS: 114122244
DCI: 103510138
CLEC: 106664391
HHAL: 106688101
FOC: 113208080
ZNE: 110830469
CSEC: 111863723
FCD: 110856956
PVM: 113827196
PJA: 122259003
HAME: 121872914
PCLA: 123768156
PTRU: 123515456
HAZT: 108683161
RMP: 119180320
CSCU: 111641472
GAE: 121385459
MYI: 110448663
LAK: 106153669
AQU: 100632989
ATH: AT5G07830(GUS2) AT5G34940(GUS3) AT5G61250(GUS1)
LJA: Lj0g3v0146829.1(Lj0g3v0146829.1) Lj0g3v0146829.2(Lj0g3v0146829.2) Lj2g3v0609680.1(Lj2g3v0609680.1) Lj4g3v1683270.1(Lj4g3v1683270.1) Lj4g3v1683270.2(Lj4g3v1683270.2) Lj4g3v1946680.1(Lj4g3v1946680.1) Lj4g3v1946680.2(Lj4g3v1946680.2) Lj6g3v1093320.1(Lj6g3v1093320.1)
DOSA: Os02t0802200-01(Os02g0802200) Os03t0211700-01(Os03g0211700) Os06t0179000-01(Os06g0179000) Os07t0598400-01(Os07g0598400) Os12t0578400-01(Os12g0578400)
SDE: Sde_3124
NAR: Saro_3674
SUB: SUB1200
STB: SGPB_0956
SIK: K710_0674
SUS: Acid_3120
 » show all
Reference
  Authors
Kussie PH, Hulmes JD, Ludwig DL, Patel S, Navarro EC, Seddon AP, Giorgio NA, Bohlen P
  Title
Cloning and functional expression of a human heparanase gene.
  Journal
Biochem Biophys Res Commun 261:183-7 (1999)
DOI:10.1006/bbrc.1999.0962
  Sequence
[hsa:10855]
LinkDB

KEGG   ORTHOLOGY: K07965
Entry
K07965                      KO                                     
Symbol
HPSE2
Name
heparanase 2 [EC:3.2.1.-]
Pathway
map00531  Glycosaminoglycan degradation
map01100  Metabolic pathways
map05205  Proteoglycans in cancer
Module
M00078  Heparan sulfate degradation
Disease
H00753  Urofacial syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00531 Glycosaminoglycan degradation
    K07965  HPSE2; heparanase 2
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    K07965  HPSE2; heparanase 2
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   00536 Glycosaminoglycan binding proteins
    K07965  HPSE2; heparanase 2
Enzymes [BR:ko01000]
 3. Hydrolases
  3.2  Glycosylases
   3.2.1  Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
    3.2.1.-
     K07965  HPSE2; heparanase 2
Glycosaminoglycan binding proteins [BR:ko00536]
 Heparan sulfate / Heparin
  Enzymes
   K07965  HPSE2; heparanase 2
Other DBs
RN: R07811
GO: 0030305
Genes
HSA: 60495(HPSE2)
PTR: 466176(HPSE2)
PPS: 100989887(HPSE2)
GGO: 101129718(HPSE2)
PON: 100437923(HPSE2)
NLE: 100595775(HPSE2)
MCC: 708795(HPSE2)
MCF: 102138349(HPSE2)
CSAB: 103216367(HPSE2)
CATY: 105581816(HPSE2)
PANU: 101022707(HPSE2)
TGE: 112631535(HPSE2)
RRO: 104682796(HPSE2)
RBB: 108534921(HPSE2)
TFN: 117068728(HPSE2)
PTEH: 111538687(HPSE2)
CJC: 100407598(HPSE2)
SBQ: 101048909(HPSE2)
CSYR: 103276543(HPSE2)
MMUR: 105873280(HPSE2)
OGA: 100953978(HPSE2)
MMU: 545291(Hpse2)
MCAL: 110285549(Hpse2)
MPAH: 110318165(Hpse2)
RNO: 368128(Hpse2)
MCOC: 116103865(Hpse2)
MUN: 110550503(Hpse2)
CGE: 100762007(Hpse2)
PLEU: 114706425(Hpse2)
NGI: 103733180(Hpse2)
HGL: 101712098(Hpse2)
CPOC: 100717156(Hpse2)
CCAN: 109699884(Hpse2)
DORD: 105986655(Hpse2)
DSP: 122115928(Hpse2)
OCU: 100359235(HPSE2)
OPI: 101534357(HPSE2)
TUP: 102495912(HPSE2)
CFA: 486831(HPSE2)
VVP: 112914666(HPSE2)
VLG: 121485537(HPSE2)
AML: 105236608(HPSE2)
UMR: 103675767(HPSE2)
UAH: 113251812(HPSE2)
ELK: 111145067
MPUF: 101685588(HPSE2)
EJU: 114205353(HPSE2)
ZCA: 113919661(HPSE2)
MLX: 118024741(HPSE2)
FCA: 101083879(HPSE2)
PYU: 121037086(HPSE2)
PBG: 122493114(HPSE2)
PTG: 102953291(HPSE2)
PPAD: 109272743(HPSE2)
AJU: 106966932(HPSE2)
HHV: 120223178
BTA: 537343(HPSE2)
BOM: 102270609(HPSE2)
BIU: 109553225(HPSE2)
BBUB: 102407242(HPSE2)
CHX: 102177683(HPSE2)
ODA: 120873515(HPSE2)
CCAD: 122446345(HPSE2)
SSC: 100157983(HPSE2)
CFR: 102517296(HPSE2)
CBAI: 105081762(HPSE2)
CDK: 105084300(HPSE2)
BACU: 102998284(HPSE2)
LVE: 103073307(HPSE2)
OOR: 101276584(HPSE2)
DLE: 111172629(HPSE2)
PCAD: 102996398(HPSE2)
PSIU: 116741589(HPSE2)
ECB: 100070602(HPSE2)
EPZ: 103562175(HPSE2)
EAI: 106847003(HPSE2)
MYB: 102240000(HPSE2)
MYD: 102764410
MMYO: 118669874(HPSE2)
MLF: 102423584(HPSE2)
MNA: 107542562(HPSE2)
PKL: 118719383(HPSE2)
HAI: 109379685(HPSE2)
SHON: 118990312(HPSE2)
AJM: 119044547(HPSE2)
PDIC: 114497813(HPSE2)
PHAS: 123828929(HPSE2)
MMF: 118632232(HPSE2)
RFQ: 117036098(HPSE2)
PALE: 102881775(HPSE2)
PGIG: 120609224(HPSE2)
PVP: 105304661
RAY: 107520389(HPSE2)
MJV: 108385480(HPSE2)
TOD: 119234200
SARA: 101547352(HPSE2)
LAV: 100666920(HPSE2)
TMU: 101359421
DNM: 101430482(HPSE2)
MDO: 100020982(HPSE2)
GAS: 123238252(HPSE2)
SHR: 100926861(HPSE2)
PCW: 110215367(HPSE2)
OAA: 100076734(HPSE2)
GGA: 423834(HPSE2)
PCOC: 116231693(HPSE2)
MGP: 104912019(HPSE2)
CJO: 107316031(HPSE2)
NMEL: 110399795(HPSE2)
APLA: 101794162(HPSE2)
ACYG: 106037073(HPSE2)
AFUL: 116491331(HPSE2)
TGU: 100228540(HPSE2)
LSR: 110473683(HPSE2)
SCAN: 103814162(HPSE2)
PMOA: 120502021(HPSE2)
OTC: 121341806(HPSE2)
PRUF: 121350354(HPSE2)
FAB: 101819889(HPSE2)
PHI: 102111700(HPSE2)
PMAJ: 107206892(HPSE2)
CCAE: 111931223(HPSE2)
CCW: 109145966(HPSE2)
ETL: 114070959(HPSE2)
ZAB: 102064163(HPSE2)
FPG: 101917114(HPSE2)
FCH: 102058821(HPSE2)
CLV: 102088744
EGZ: 104129081(HPSE2)
NNI: 104013727(HPSE2)
ACUN: 113481582(HPSE2)
TALA: 104368314(HPSE2)
PADL: 103916340(HPSE2)
ACHC: 115347997(HPSE2)
AAM: 106494693(HPSE2)
AROW: 112967968(HPSE2)
NPD: 112957066(HPSE2)
DNE: 112984803(HPSE2)
ASN: 102380123(HPSE2)
AMJ: 102560537(HPSE2)
CPOO: 109323842(HPSE2)
GGN: 109287163(HPSE2)
CMY: 102946175(HPSE2)
CPIC: 101951758(HPSE2)
TST: 117880327(HPSE2)
CABI: 116829608(HPSE2)
MRV: 120368970(HPSE2)
ACS: 100564973(hpse2)
PVT: 110084049(HPSE2)
SUND: 121927247(HPSE2)
PBI: 103059374(HPSE2)
PMUR: 107287746(HPSE2)
TSR: 106548177(HPSE2)
PGUT: 117678583(HPSE2)
VKO: 123033500(HPSE2)
PMUA: 114597604(HPSE2)
ZVI: 118093811(HPSE2)
GJA: 107114417(HPSE2) 107121129
XLA: 108696172(hpse2.L)
XTR: 100485493(hpse2)
NPR: 108787514(HPSE2)
RTEM: 120946669(HPSE2)
BBUF: 121004786(HPSE2)
BGAR: 122941489(HPSE2) 122942206
DRE: 562573(hpse2)
SGH: 107586094 107601035(hpse2)
IPU: 108262814(hpse2)
PHYP: 113545209(hpse2)
SMEO: 124402333(hpse2)
AMEX: 103034333(hpse2)
EEE: 113585908(hpse2)
TRU: 101080039(hpse2)
LCO: 104930784(hpse2)
NCC: 104955141(hpse2)
CGOB: 115020089(hpse2)
ELY: 117247933(hpse2)
PLEP: 121954652(hpse2)
SLUC: 116053892(hpse2)
ECRA: 117960137(hpse2)
PFLV: 114572272(hpse2)
GAT: 120820707
PPUG: 119213759(hpse2)
MSAM: 119917592(hpse2)
CUD: 121511091(hpse2)
MZE: 101464618(hpse2)
ONL: 100704811(hpse2)
OAU: 116335135(hpse2)
OLA: 101164248(hpse2)
OML: 112161442(hpse2)
XMA: 102220259(hpse2)
XCO: 114138527(hpse2)
XHE: 116713750(hpse2)
PRET: 103476909(hpse2)
PFOR: 103152246(hpse2)
PLAI: 106947272(hpse2)
PMEI: 106916427(hpse2)
GAF: 122842393(hpse2)
CVG: 107088632(hpse2)
CTUL: 119790715(hpse2)
NFU: 107375674(hpse2)
KMR: 108233958(hpse2)
ALIM: 106528207(hpse2)
NWH: 119418323(hpse2)
AOCE: 111578274(hpse2)
CSEM: 103387298(hpse2)
POV: 109631478(hpse2)
SSEN: 122781662(hpse2)
HHIP: 117775351(hpse2)
LCF: 108884124(hpse2)
SDU: 111235152(hpse2)
SLAL: 111654696(hpse2)
XGL: 120796138(hpse2)
HCQ: 109512722(hpse2)
BPEC: 110156904(hpse2)
MALB: 109961145(hpse2)
SASA: 106612917(hpse2)
OMY: 110499532 118943876(hpse2)
ONE: 115113852
SALP: 112080523
SNH: 120045956(hpse2)
ELS: 105021381(hpse2)
SFM: 108942734(hpse2)
PKI: 111849601(hpse2)
AANG: 118218311(hpse2)
LOC: 102695586(hpse2)
ARUT: 117415764(hpse2) 117417872
LCM: 102359157(HPSE2)
CMK: 103188922
RTP: 109913676
HRJ: 124279719
 » show all
Reference
PMID:1027606
  Authors
Mehta PV
  Title
Value of cyclic hormonal assessment by vaginal cytology in infertile women.
  Journal
J Obstet Gynaecol India 26:111-6 (1976)
  Sequence
[hsa:60495]
LinkDB

KEGG   ENZYME: 3.2.1.166
Entry
EC 3.2.1.166                Enzyme                                 
Name
heparanase;
Hpa1 heparanase;
Hpa1;
heparanase 1;
heparanase-1;
C1A heparanase;
HPSE
Class
Hydrolases;
Glycosylases;
Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
Sysname
heparan sulfate N-sulfo-D-glucosamine endoglucanase
Reaction(IUBMB)
endohydrolysis of (1->4)-beta-D-glycosidic bonds of heparan sulfate chains in heparan sulfate proteoglycan
Reaction(KEGG)
(other) R07811(G)
Comment
Heparanase cleaves the linkage between a glucuronic acid unit and an N-sulfo glucosamine unit carrying either a 3-O-sulfo or a 6-O-sulfo group [2]. Heparanase-1 cuts macromolecular heparin into fragments of 5000--20000 Da [5]. The enzyme cleaves the heparan sulfate glycosaminoglycans from proteoglycan core proteins and degrades them to small oligosaccharides. Inside cells, the enzyme is important for the normal catabolism of heparan sulfate proteoglycans, generating glycosaminoglycan fragments that are then transported to lysosomes and completely degraded. When secreted, heparanase degrades basement membrane heparan sulfate glycosaminoglycans at sites of injury or inflammation, allowing extravasion of immune cells into nonvascular spaces and releasing factors that regulate cell proliferation and angiogenesis [1].
History
EC 3.2.1.166 created 2010
Pathway
ec00531  Glycosaminoglycan degradation
ec01100  Metabolic pathways
Orthology
K07964  heparanase
Genes
HSA10855(HPSE)
PTR461206(HPSE)
PPS100996218(HPSE)
GGO101150800(HPSE)
PON100448281(HPSE)
NLE100596185(HPSE)
MCC707583(HPSE)
MCF102123028(HPSE)
CSAB103235901(HPSE)
CATY105576795(HPSE)
PANU101008008(HPSE)
TGE112624635(HPSE)
RRO104658833(HPSE)
RBB108531149(HPSE)
TFN117085378(HPSE)
PTEH111549300(HPSE)
CJC100402671(HPSE)
SBQ101043067(HPSE)
CSYR103265158(HPSE)
MMUR105872605(HPSE)
OGA100965397(HPSE)
MMU15442(Hpse)
MCAL110294241(Hpse)
MPAH110330557(Hpse)
RNO64537(Hpse)
MCOC116067960(Hpse)
MUN110553884(Hpse)
CGE100755610(Hpse)
PLEU114691766(Hpse)
NGI103744984(Hpse)
HGL101721140(Hpse)
CPOC100721886(Hpse)
CCAN109683307(Hpse)
DORD105988588(Hpse)
DSP122097868(Hpse)
OCU100101601(HPSE)
OPI101525206(HPSE)
TUP102501533(HPSE)
CFA608707(HPSE)
VVP112919568(HPSE)
VLG121493930(HPSE)
AML100470911(HPSE)
UMR103665420(HPSE)
UAH113263199(HPSE)
UAR123787859(HPSE)
ELK111149020
MPUF101688281(HPSE)
ORO101371822(HPSE)
EJU114224914(HPSE)
ZCA113925912(HPSE)
MLX118010381(HPSE)
FCA101090101(HPSE)
PYU121033261(HPSE)
PBG122478708(HPSE)
PTG102965445(HPSE)
PPAD109276572(HPSE)
AJU106987077(HPSE)
HHV120246450(HPSE)
BTA281230(HPSE)
BOM102265641(HPSE)
BIU109560640(HPSE)
BBUB102395500(HPSE)
CHX102188207(HPSE)
OAS101118612(HPSE)
ODA120861521(HPSE)
CCAD122428283(HPSE)
SSC100271932(HPSE)
CFR102517816(HPSE)
CBAI105065287(HPSE)
CDK105092018(HPSE)
BACU102999760(HPSE)
LVE103084178(HPSE)
OOR101283118(HPSE)
DLE111187577(HPSE)
PCAD102985869(HPSE)
PSIU116754204(HPSE)
ECB100061267(HPSE)
EPZ103549090(HPSE)
EAI106846420(HPSE)
MYB102245458(HPSE)
MYD102774009(HPSE)
MMYO118670781(HPSE)
MLF102436832(HPSE)
MNA107537105(HPSE)
PKL118704413(HPSE)
HAI109387924(HPSE)
DRO112317780(HPSE)
SHON118979540(HPSE)
AJM119054621(HPSE)
PDIC114492003(HPSE)
PHAS123806934(HPSE)
MMF118640491(HPSE)
RFQ117022519(HPSE)
PALE102888805(HPSE)
PGIG120588285(HPSE)
PVP105289595(HPSE)
RAY107516475(HPSE)
MJV108394108(HPSE)
TOD119260898(HPSE)
LAV100676520(HPSE)
TMU101360212
DNM101444076(HPSE)
MDO100026183(HPSE)
GAS123251465(HPSE)
SHR100923804(HPSE)
PCW110209762(HPSE)
GGA373981(HPSE)
PCOC116231114(HPSE)
MGP100545679(HPSE)
CJO107313425(HPSE)
NMEL110399069(HPSE)
APLA101797825(HPSE)
ACYG106041934(HPSE)
AFUL116489002(HPSE)
TGU100218163(HPSE)
LSR110468522(HPSE)
SCAN103826088(HPSE)
PMOA120496083(HPSE)
OTC121339835(HPSE)
PRUF121360463(HPSE)
GFR102040930(HPSE)
FAB101809526(HPSE)
PHI102109966(HPSE)
PMAJ107203573(HPSE)
CCAE111928869(HPSE)
CCW104697252(HPSE)
ETL114057759(HPSE)
ZAB102062765(HPSE)
FPG101912317(HPSE)
FCH102057366(HPSE)
CLV102085346(HPSE)
EGZ104127343(HPSE)
NNI104014988(HPSE)
ACUN113479584(HPSE)
TALA104365048(HPSE)
PADL103919913(HPSE)
ACHC115338962(HPSE)
AAM106494822(HPSE)
AROW112970688(HPSE)
NPD112951906(HPSE)
DNE112990443(HPSE)
ASN102369021
AMJ102571669(HPSE)
CPOO109321870(HPSE)
GGN109303678(HPSE)
PSS102450514(HPSE)
CMY102946031(HPSE)
CPIC101942907(HPSE)
TST117878215(HPSE)
CABI116836664(HPSE)
MRV120406245(HPSE)
ACS100565376(hpse)
PVT110083349(HPSE)
SUND121932136(HPSE)
PBI103050955(HPSE)
PMUR107303159(HPSE)
PGUT117673663(HPSE)
VKO123022631(HPSE)
PMUA114604526(HPSE)
ZVI118083498(HPSE)
GJA107116059(HPSE)
XLA108719705(hpse.L)
XTR100145320(hpse)
NPR108804446(HPSE)
RTEM120915912(HPSE)
BBUF120989721(HPSE)
BGAR122945288(HPSE)
DRE563020(hpse)
SRX107722827(hpse)
SANH107681091(hpse) 107703469
SGH107589237(hpse) 107591750
CCAR109045517 109046365 109083888
CAUA113038734 113064200
IPU108278991(hpse)
PHYP113543026(hpse)
SMEO124398473(hpse)
AMEX103027675(hpse)
EEE113570752(hpse)
TRU101076415(hpse)
TNGGSTEN00001168G001 GSTEN00010356G001
LCO104939605(hpse)
NCC104957343
CGOB115005073(hpse)
ELY117270168(hpse)
PLEP121959693(hpse)
SLUC116041823(hpse)
PFLV114571209(hpse)
PPUG119227058(hpse)
MSAM119914560(hpse)
CUD121524728(hpse)
MZE101471023(hpse)
ONL100704102(hpse)
OAU116321504(hpse)
OLA101156941(hpse)
OML112162914(hpse)
XMA102231016(hpse)
XCO114150028(hpse)
XHE116724936(hpse)
PRET103473150(hpse)
PFOR103152308(hpse)
PLAI106947039(hpse)
PMEI106904036(hpse)
GAF122819209(hpse)
CVG107100851(hpse)
CTUL119797736(hpse)
NFU107390264(hpse)
KMR108242518(hpse)
ALIM106524410(hpse)
NWH119425089(hpse)
CSEM103390393(hpse)
POV109648055
SSEN122787041(hpse)
HHIP117771320(hpse)
LCF108892286(hpse)
SDU111238027(hpse)
SLAL111651357 111652372
XGL120806035(hpse)
HCQ109517543(hpse)
BPEC110161656(hpse)
SASA106563622(hpse) 106568158
OTW112219520(hpse)
OMY110523793(hpse)
OGO124048738(hpse)
ONE115105879 115125824
SALP111961401 111981971
SNH120026458(hpse) 120044991
ELS105014724(hpse)
SFM108935179(hpse)
PKI111842231(hpse)
AANG118212115(hpse)
LOC102686050(hpse)
PSPA121303644(hpse)
ARUT117408892 117420934
LCM102346905(HPSE)
CMK103187960(hpse)
RTP109935286(hpse)
BFO118413989
BBEL109471425
CIN100178996 100185909
SCLV120344732 120345034
SPU586860 763558
APLC110974251 110984533
SKO100376015 102801119 102804856
AME725623
ACER107996324
ALAB122712848
BIM100745198
BBIF117209398
BVK117240191
BVAN117164389
BTER105666557
BPYO122575821
CCAL108630640
OBB114877484
MGEN117218147
NMEA116431518
CGIG122405059
SOC105193112
MPHA105836142
AEC105154939
ACEP105626290
PBAR105430094
VEM105559915
HST105180876
DQU106751247
CFO105248467
FEX115237339
LHU105671110
PGC109853681
OBO105281678
PCF106786988
PFUC122515261
VPS122636119
NVI100113700
CSOL105368274
TPRE106659608
MDL103580115
CGLO123271325
FAS105263758
DAM107038411
AGIF122852847 122852848
CCIN107263116
TCA659639
DPA109535884 109541637 109545353 109545371
SOY115874561
ATD109608715
CSET123310036
AGB108905388
LDC111502285
NVL108564172
PPYR116168839 116169481 116169945
OTU111415667
BMOR100141461(Hepa) 101744388
BMAN114241567 114250016
MSEX115451084
DPLKGM_207163
BANY112042805
PMAC106716208 106717291
PPOT106104492
PXU106116071 106126423
PRAP110998158
ZCE119835673
HAW110374496
TNL113506141
OFU114359330
PXY105379996 105384116
AGS114122244
DCI103510138
CLEC106664391
HHAL106688101
PHUPhum_PHUM168420
FOC113208080
ZNE110830469
CSEC111863723
FCD110856956
PVM113827196
PJA122259003
HAME121872914
PCLA123768156
PTRU123515456
HAZT108683161
ISCIscW_ISCW005785
DSV119444644 119452400
RSAN119391492 119391525
RMP119180320
CSCU111641472
HROHELRODRAFT_161090
LGILOTGIDRAFT_159759 LOTGIDRAFT_159761 LOTGIDRAFT_231761
PCAN112556154 112556225 112556228 112557171 112557172 112558223
BGT106057424 106058459 106059621 106074413
GAE121385459
HRF124110777 124110789 124110790 124116504 124116509 124116511 124116512 124116513 124116514 124116515 124116521 124116522 124116523 124116534 124116535 124116536 124116537 124121772 124121777 124121783 124121785 124121789 124125343 124125344 124125346 124125348 124125350 124125351 124128144 124129035 124129036 124129046 124129047 124129102 124129103 124139296
HRJ124263021 124263022 124263026 124263028 124263029 124263038 124273906 124273970 124273972 124275049 124278350 124278401 124279718 124279724 124291163 124291166 124291175
CRG105320771 105335864
MYI110448663
PMAX117320605 117339362
OBI106874146 106878007
OSN115219045 115223331
LAK106153669
NVE5503802 5514619
EPA110238002 110246297 110251524
ATEN116296587 116297207
ADF107330651 107338790 107354788
AMIL114958108 114973352
PDAM113670022 113683983
SPIS111329059 111340113
DGT114530656 114531089
XEN124452785 124452977
HMG100197518 100208368 100209357 100212115 100213628
AQU100632989
ATHAT5G07830(GUS2) AT5G34940(GUS3) AT5G61250(GUS1)
ALY9300803 9304475 9309395
CRB17876259 17879794 17882401
CSAT104708318 104723958 104726711 104732492 104734801 104738603 104762235 104768989 109124769
EUSEUTSA_v10003449mg EUTSA_v10003960mg EUTSA_v10013186mg
BRP103833744 103847113 103860580
BNA106390991 106411460 106418750 106419402 106439933 106442442 106446111 106449539
BOE106306275 106311798 106318846
RSZ108805374 108805377 108818286 108822215 108822216
THJ104808955 104818330 104823068
CPAP110807038 110813997 110814890 110814892 110826122
CIT102608348 102610770 102611386 102614850
CICCICLE_v10007919mg CICLE_v10010401mg CICLE_v10019304mg CICLE_v10033641mg
PVY116107765 116110729 116127842 116138112
MINC123194235 123194317 123200101 123204673 123211671 123215087
TCC18587757 18588859 18604781 18610294
GRA105764689 105772991 105774985 105775732 105775737 105776412 105784755 105784760 105784888 105791045 105793016 105800791
GHI107889831 107889837 107889841 107889855 107889857 107889859 107889860 107889861 107892792 107892793 107892794 107898765 107901340 107912568 107921522 107931497 107931769 107931771 107935298 107936659 107940072 107940344 107940350 107944290 107944415 107944416 107944490 107948692 107951250 107962572 121206435 121211039 121222585
GAB108454253 108455030 108455146 108455340 108455346 108455680 108458812 108462212 108462276 108462532 108465217 108468340 108476607 108487736
DZI111284000 111284616 111285922 111289766 111299019 111300444 111309868
EGR104420262 104425993 104435597 104437643 104437644 104437646 104438623 104455742
GMX100778008 100782283 100791916 100792087 100792792 100802477 100803057 100804120 100806170 100807012 100813746 102662422 106797823
GSJ114367922 114370927 114373529 114387148 114387173 114388511 114391814 114394259 114409685 114411824 114416590
PVUPHAVU_002G081000g PHAVU_002G087100g PHAVU_003G171800g PHAVU_003G186600g PHAVU_009G212400g
VRA106755278 106757654 106759630 106765702 106766847 106779320
VAR108324912 108332102 108334817 108341585 108345696
VUN114164379 114174552 114174993 114176086 114195991
CCAJ109790939 109791987 109800324 109808388 109808708 109809088 109816308 109817145
APRC113846764 113847019 113847674 113874397
MTRMTR_2g451510 MTR_3g023690 MTR_3g023700 MTR_3g023710 MTR_4g109300 MTR_4g116040 MTR_4g116070 MTR_5g043710 MTR_8g091920
CAM101492700 101493679 101494689 101512767
LJALj0g3v0146829.1(Lj0g3v0146829.1) Lj0g3v0146829.2(Lj0g3v0146829.2) Lj2g3v0609680.1(Lj2g3v0609680.1) Lj4g3v1683270.1(Lj4g3v1683270.1) Lj4g3v1683270.2(Lj4g3v1683270.2) Lj4g3v1946680.1(Lj4g3v1946680.1) Lj4g3v1946680.2(Lj4g3v1946680.2) Lj6g3v1093320.1(Lj6g3v1093320.1)
ADU107461469 107463529 107467607 107467610 107468441 107479641 107483006 110273829
AIP107616242 107616246 107622715 107630530 107632651 107634143 107635977 107640604 110269501
AHF112701435 112701647 112708197 112709578 112709839 112713110 112722554 112723342 112732305 112732934 112741400 112742190 112779114 112779116 112782406 112790775 112794576
LANG109328476 109328497 109344408 109346015 109346028 109354727 109359565 109361472 109362217
FVE101292576 101293484 101295230 101309586
RCN112174790 112179656 112186967 112195831
PPER18771157 18777307 18777487 18789359 18790621
PMUM103319726 103321505 103338454 103341177
PAVI110751373 110752594 110762334 110763760
PDUL117614286 117622566 117627179 117628841 117633846
MDM103400053 103403264 103437866 103447604 103455399 103456224
PXB103930738 103930972 103931364 103946731 103949167 103953861
ZJU107415693 107419148 107421162 107421895 107428862 107428871 107428875 107428876 107428889
MNT21387755 21391881 21398356 21406434
CSV101205085 101212628 101213640 101213905 101214214 101215378 101220813
CMO103483878 103489169 103489677 103494021 103496979 103504453
BHJ120069563 120071404 120074064 120080459 120082143 120083544
MCHA111006827 111008890 111009126 111009315 111013018 111019094 111023940 111024442
CMAX111465495 111466170 111466171 111466172 111470271 111471079 111479365 111482540 111492865 111493713
CMOS111432361 111440858 111444334 111446673 111450316 111450381 111452576 111457886 111458782
CPEP111777618 111781603 111787560 111791689 111793488 111798526 111800534 111800538 111805339
RCU8259416 8277627 8284471 8289141
JCU105630519 105630955 105637606 105640593 105641248
HBR110636252 110639175 110642663 110643395 110646174 110646178 110646179 110646183 110649820 110654012 110656929 110672735
MESC110599811 110610876 110616739 110617506 110619421 110631248
POP18099898 18111056 7453857 7465402 7492893
PEU105116645 105117201 105121093 105122679 105134054
PALZ118032623 118037326 118042979 118051264
JRE108990997 108992197 109002527 109002802 109005442
QSU111985586 111989393 112029649 112029650 112040761
QLO115963513 115963514 115964675 115964693 115974913 115977140
TWL119980344 119987101 119987102 119996257 119997687 120002555 120016673
VVI100254131 100255842 100257028 100259360 100264535
VRI117904698 117912445 117913450 117914322 117925155
SLY101256537 101257181 101258638 101258669 101264423
SPEN107015467 107019237 107023336 107025866 107032105
SOT102579755 102580456 102580531 102602354 102606348
CANN107843440 107846992 107852403 107855392 107862297
NTA107789624 107798119 107799043 107813165 107813759 107827511 107828335 107829601(GUS2) 107830348 107832071
NSY104210356 104213374 104231812 104239748 104247501
NTO104091671 104106070 104114370 104116644 104121626
NAU109211330 109220091 109220417 109227490 109233303
INI109162793 109164147 109166262 109178730 109193594
ITR115996754 116011009 116014068 116026340 116031656
SIND105156507 105157963 105160089 105162244 105164556
OEU111366012 111368355 111372375 111398847 111400505
EGT105951046 105956966 105956987 105960660 105967433 105974584 105977117
SSPL121748249 121752016 121752909 121752994 121762008 121765232 121769498 121770056 121785257 121798055
HAN110865632 110877363 110886626 110893915 110898566 110912161 110917272 110944865
ECAD122584969 122588862 122593794 122596194 122602000 122606856
LSV111881906 111882268 111889027 111895156 111908364 111910485
CCAV112507267 112509880 112511274 112516687 112519873 112520204 112521617
DCR108192341 108193209 108194272 108198601 108198690 108208766 108211803 108215837 108220198 108224512
CSIN114278227 114284424 114285617 114305380 114309939 114309940 114310467
BVG104882804 104893978 104901937 104902375
SOE110789406 110799945 110801137
CQI110685651 110700661 110705461 110708041 110722142 110725531 110726389 110733623
NNU104592548 104598002 104598612
MING122079887 122083645 122090927 122090928
TSS122650329 122654626 122654870 122671697
PSOM113272674 113279136 113300231 113319478 113343128 113349882
NCOL116252237 116255575 116256388 116256495 116257956
OSA4331042 4332033 4340299 4343804 4352626
DOSAOs02t0802200-01(Os02g0802200) Os03t0211700-01(Os03g0211700) Os06t0179000-01(Os06g0179000) Os07t0598400-01(Os07g0598400) Os12t0578400-01(Os12g0578400)
OBR102704215 102707920 102718196 102718721 102720994
BDI100827936 100834568 100837386 100838514
ATS109736222 109750281 109770916 109777268 109780669
TDC119284894 119291241 119299596 119307664 119318364 119324056 119329056 119336914 119357750 119360787
TAES123041047 123049055 123085047 123093006 123098288 123102439 123110614 123119642 123128828 123139260 123145970 123147564 123160521 123161544 123167860 123168459 123185037
SBI8065389 8067461 8068132 8084653
ZMA100192026 100193781 100279495 100285720 100501670 103640342
SITA101758357 101761220 101762752 101785921
SVS117839915 117841426 117848276 117852916
PVIR120645233 120646895 120657509 120666582 120670089 120691015 120699897 120702797
PHAI112874533 112879016 112884792 112891166
PDA103704453 103709282 103710119 103715887 103718168
EGU105032253 105033054 105046630 105049420 105055993 105056031
MUS103979337 103980064 103980543 103982167 103983605 103992113
DCT110095528 110097241 110098134 110099407 110109652 110114766 110116311
PEQ110020130 110024422 110026960 110029134 110030614 110031280 110032014 110035536
AOF109822035 109834102 109835733 109849518 109851214
ATR18427936 18427937 18442559
SMOSELMODRAFT_105931 SELMODRAFT_133100 SELMODRAFT_133227 SELMODRAFT_32458 SELMODRAFT_52894
PPP112274848 112286717 112287451 112289377
MBRMONBRDRAFT_22110 MONBRDRAFT_24839 MONBRDRAFT_26729 MONBRDRAFT_29948 MONBRDRAFT_30511 MONBRDRAFT_34413
SREPTSG_00821
TPSTHAPSDRAFT_bd1944
AAFAURANDRAFT_3240 AURANDRAFT_64495
EHXEMIHUDRAFT_194815 EMIHUDRAFT_52085
GTTGUITHDRAFT_142083
PLULFOB45_02175
CATEC2869_18390
SDESde_3124
TTUTERTU_3487
SPOIIMCC21906_01609
MMWMmwyl1_1639
MMEMarme_2892
MPCMar181_2151
MPRIMP3633_2421
MARDIBG28_13470
MFOIJSY38_02980
GSNYC6258_03119
BRKCWS35_16545
NTDEGO55_04735
NARSaro_3674
NOVTQ38_017855
SYAA6768_14080
SANDH3309_16090
OCNCUC15_05820
OCBCV093_06150
SUBSUB1200
STBSGPB_0956
SIKK710_0674
SIQDQ08_03240
SIODW64_03230
SMENSAMEA4412692_0439
RHORHOM_14650
SCDSpica_0071
SSMSpirs_0259
TSAAciPR4_4030
TALBFTW19_21690
SUSAcid_3120
PFERIRI77_15190
ABACLuPra_05369
MCOSGM418_21645
SPIRCWM47_02705
RUNDR864_23200
RUPDTQ70_06315
EMARD1013_08510
 » show all
Reference
1  [PMID:11445547]
  Authors
Bame KJ
  Title
Heparanases: endoglycosidases that degrade heparan sulfate proteoglycans.
  Journal
Glycobiology 11:91R-98R (2001)
DOI:10.1093/glycob/11.6.91R
Reference
2  [PMID:20181948]
  Authors
Peterson SB, Liu J
  Title
Unraveling the specificity of heparanase utilizing synthetic substrates.
  Journal
J Biol Chem 285:14504-13 (2010)
DOI:10.1074/jbc.M110.104166
  Sequence
[hsa:10855]
Reference
3  [PMID:9668050]
  Authors
Pikas DS, Li JP, Vlodavsky I, Lindahl U
  Title
Substrate specificity of heparanases from human hepatoma and platelets.
  Journal
J Biol Chem 273:18770-7 (1998)
DOI:10.1074/jbc.273.30.18770
Reference
4  [PMID:12213822]
  Authors
Okada Y, Yamada S, Toyoshima M, Dong J, Nakajima M, Sugahara K
  Title
Structural recognition by recombinant human heparanase that plays critical roles  in tumor metastasis. Hierarchical sulfate groups with different effects and the essential target disulfated trisaccharide sequence.
  Journal
J Biol Chem 277:42488-95 (2002)
DOI:10.1074/jbc.M206510200
  Sequence
[hsa:10855]
Reference
5  [PMID:17635638]
  Authors
Vreys V, David G
  Title
Mammalian heparanase: what is the message?
  Journal
J Cell Mol Med 11:427-52 (2007)
DOI:10.1111/j.1582-4934.2007.00039.x
Reference
6  [PMID:12837765]
  Authors
Gong F, Jemth P, Escobar Galvis ML, Vlodavsky I, Horner A, Lindahl U, Li JP
  Title
Processing of macromolecular heparin by heparanase.
  Journal
J Biol Chem 278:35152-8 (2003)
DOI:10.1074/jbc.M300925200
  Sequence
[mmu:15442]
Reference
7  [PMID:10446189]
  Authors
Toyoshima M, Nakajima M
  Title
Human heparanase. Purification, characterization, cloning, and expression.
  Journal
J Biol Chem 274:24153-60 (1999)
DOI:10.1074/jbc.274.34.24153
  Sequence
[hsa:10855]
Reference
8  [PMID:12460766]
  Authors
Miao HQ, Navarro E, Patel S, Sargent D, Koo H, Wan H, Plata A, Zhou Q, Ludwig D, Bohlen P, Kussie P
  Title
Cloning, expression, and purification of mouse heparanase.
  Journal
Protein Expr Purif 26:425-31 (2002)
DOI:10.1016/S1046-5928(02)00558-2
  Sequence
[mmu:15442]
Reference
9  [PMID:19748475]
  Authors
Hammond E, Li CP, Ferro V
  Title
Development of a colorimetric assay for heparanase activity suitable for kinetic  analysis and inhibitor screening.
  Journal
Anal Biochem 396:112-6 (2010)
DOI:10.1016/j.ab.2009.09.007
Other DBs
ExplorEnz - The Enzyme Database: 3.2.1.166
IUBMB Enzyme Nomenclature: 3.2.1.166
ExPASy - ENZYME nomenclature database: 3.2.1.166
BRENDA, the Enzyme Database: 3.2.1.166
LinkDB

KEGG   REACTION: R07811
Entry
R07811                      Reaction                               
Definition
Heparan sulfate + H2O <=> Heparan sulfate + G13034
Equation
Enzyme
3.2.1.166       3.2.1.-
Pathway
rn00531  Glycosaminoglycan degradation
rn01100  Metabolic pathways
Module
M00078  Heparan sulfate degradation
Orthology
K07964  heparanase [EC:3.2.1.166]
K07965  heparanase 2 [EC:3.2.1.-]
LinkDB

DBGET integrated database retrieval system