KEGG   ORTHOLOGY: K08092
Entry
K08092                      KO                                     
Symbol
dlgD
Name
3-dehydro-L-gulonate 2-dehydrogenase [EC:1.1.1.130]
Pathway
map00040  Pentose and glucuronate interconversions
map00053  Ascorbate and aldarate metabolism
map01100  Metabolic pathways
Reaction
R02637  3-dehydro-L-gulonate:NAD+ 2-oxidoreductase
R02639  3-dehydro-L-gulonate:NADP+ 2-oxidoreductase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00040 Pentose and glucuronate interconversions
    K08092  dlgD; 3-dehydro-L-gulonate 2-dehydrogenase
   00053 Ascorbate and aldarate metabolism
    K08092  dlgD; 3-dehydro-L-gulonate 2-dehydrogenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.130  3-dehydro-L-gulonate 2-dehydrogenase
     K08092  dlgD; 3-dehydro-L-gulonate 2-dehydrogenase
Other DBs
COG: COG2055
GO: 0047559
Genes
ECO: b3575(yiaK)
ECJ: JW3547(yiaK)
ECD: ECDH10B_3756(yiaK)
EBW: BWG_3265(yiaK)
ECOK: ECMDS42_3012(yiaK)
ECOC: C3026_19385
EOI: ECO111_4395(yiaK)
EOJ: ECO26_5026(yiaK)
EOH: ECO103_4659(yiaK)
ESL: O3K_00975
ESO: O3O_24700
ESM: O3M_01005
ECK: EC55989_4032(yiaK)
ECG: E2348C_3827(yiaK)
ELH: ETEC_3818
ECW: EcE24377A_4072(dlgD)
EUN: UMNK88_4360
ECP: ECP_3679
ENA: ECNA114_3727(yiaK)
ECOS: EC958_3982(yiaK)
ECV: APECO1_2875(yiaK)
ECOA: APECO78_21690
ECX: EcHS_A3779(dlgD)
ECM: EcSMS35_3898(dlgD)
ECY: ECSE_3851
ECR: ECIAI1_3742(yiaK)
ECQ: ECED1_4263(yiaK)
EUM: ECUMN_4088(yiaK)
ECT: ECIAI39_4087(yiaK)
EOC: CE10_4129(yiaK)
EBR: ECB_03427(yiaK)
ECOB: C3029_21970
EBL: ECD_03427(yiaK)
EBE: B21_03378(yiaK)
EBD: ECBD_0159
ECI: UTI89_C4117(yiaK)
EIH: ECOK1_4022(dlgD)
ECZ: ECS88_3994(yiaK)
ECC: c4396(yiaK)
ELO: EC042_3881(dlgD)
ELN: NRG857_17800
ESE: ECSF_3410
ECL: EcolC_0139
EKO: EKO11_0151
EKF: KO11_04845(yiaK)
EAB: ECABU_c40180(dlgD)
EDH: EcDH1_0135
EDJ: ECDH1ME8569_3456(yiaK)
ELU: UM146_18045
ELW: ECW_m3849(yiaK)
ELL: WFL_18795(yiaK)
ELC: i14_4063(yiaK)
ELD: i02_4063(yiaK)
ELP: P12B_c3704(yiaK)
ELF: LF82_3339(yiaK)
ECOL: LY180_18385
ECOI: ECOPMV1_03913(dlgD)
ECOJ: P423_19890
EFE: EFER_3573(yiaK)
EAL: EAKF1_ch2371c
EMA: C1192_15920
ESZ: FEM44_09065
ERUY: OSH18_12085(yiaK)
STY: STY4130
STT: t3851
SEX: STBHUCCB_40640
SENT: TY21A_19565
STM: STM3668(yiaK)
SEO: STM14_4425(yiaK)
SEV: STMMW_36561
SEY: SL1344_3633(yiaK)
SEM: STMDT12_C37250
SEJ: STMUK_3654(yiaK)
SEB: STM474_3840(yiaK)
SEF: UMN798_3985
SETU: STU288_18530
SETC: CFSAN001921_22105
SENR: STMDT2_35521
SEND: DT104_36511
SENI: CY43_19040
SEEN: SE451236_02580
SPT: SPA3519(yiaK)
SEK: SSPA3286
SPQ: SPAB_04559
SEI: SPC_3748(yiaK)
SEH: SeHA_C3991
SHB: SU5_04145
SENH: CFSAN002069_13700
SEEH: SEEH1578_04425
SEE: SNSL254_A3946
SENN: SN31241_2150
SEW: SeSA_A3866
SEA: SeAg_B3882
SENS: Q786_17920
SED: SeD_A4053
SEG: SG3763(yiaK)
SEL: SPUL_3897(yiaK)
SEGA: SPUCDC_3883(yiaK)
SET: SEN3490(yiaK)
SENA: AU38_17830
SENO: AU37_18020
SENV: AU39_18025
SENQ: AU40_20080
SENL: IY59_18465
SENJ: CFSAN001992_15305
SEEC: CFSAN002050_25310
SEEB: SEEB0189_001535
SEEP: I137_18700
SENB: BN855_37560
SENE: IA1_17815
SENC: SEET0819_02100
SALZ: EOS98_00910
SFL: SF3619(yiaK)
SFX: S4150(yiaK)
SFV: SFV_3965(yiaK)
SFE: SFxv_3943(yiaK)
SFN: SFy_5156
SFS: SFyv_5232
SFT: NCTC1_03914(yiaK)
SBO: SBO_3583(yiaK)
SBC: SbBS512_E3947(dlgD)
SHQ: A0259_21705
ENC: ECL_00191
ENL: A3UG_00985
ECLG: EC036_01840
ECLE: ECNIH2_22595
ECLI: ECNIH5_21115
ECLX: LI66_21885
ECLY: LI62_23905
ECLO: ENC_47440
EHM: AB284_02935
EXF: BFV63_21225
ECLA: ECNIH3_21195
ECLC: ECR091_21125
EEC: EcWSU1_00160(dlgD)
ELG: BH714_15955
ECAN: CWI88_00910
ERN: BFV67_00725
ECLS: LI67_001705
ECHG: FY206_00880
ESH: C1N69_00775
EAS: Entas_0167
ENF: AKI40_2078(yiaK)
LNI: CWR52_11755
EBG: FAI37_05810
ENS: HWQ15_07205(yiaK)
ENK: LOC22_09765(yiaK)
EHU: D5067_0022360
EMOR: L6Y89_21365(yiaK)
EQU: OM418_00745(yiaK)
EPU: QVH39_00765(yiaK)
KPE: KPK_0166(dlgD)
KVD: KR75_07255
KOX: KOX_05675
KOE: A225_5605
KOY: J415_04080
KOM: HR38_04170
KOK: KONIH1_28205
KOC: AB185_08195
KQV: B8P98_00955
KLL: BJF97_27840
KLW: DA718_01050
KAR: LGL98_00900(yiaK)
KGR: JJJ10_00975(yiaK)
KPAS: LUW96_05610(yiaK)
KLC: K7H21_00915(yiaK)
KLM: BWI76_27080
REE: electrica_00162(dlgD)
ROR: RORB6_19620
RON: TE10_01345
RAO: DSD31_00925
CKO: CKO_05033
CFD: CFNIH1_05490
CBRA: A6J81_18070
CWE: CO701_22940
CFQ: C2U38_26735
CIF: AL515_00420
CIE: AN232_05315
CPAR: CUC49_18435
CITZ: E4Z61_17830
CARS: E1B03_25335
CIX: M4I31_00840(yiaK)
ESC: Entcl_0163
KLE: AO703_20620
KOR: AWR26_18130(yiaK)
KRD: A3780_06125
KOO: O9K67_17730(yiaK)
KOU: C0557_06555
KAS: KATP_01750(dlgD_1) KATP_21200(dlgD_2)
LAZ: A8A57_00930
LEF: LJPFL01_0151
LEW: DAI21_03610
BFT: MNO13_13410(yiaK)
BSEL: RHD99_07420(yiaK)
KIN: AB182_26300
PDZ: HHA33_03015(yiaK)
METY: MRY16398_01670(dlgD)
IZH: FEM41_13790
PSGC: G163CM_37550(dlgD)
SUPE: P0H77_01115(yiaK) P0H77_19615(yiaK)
EBF: D782_0150
EBC: C2U52_09105
EBB: F652_2161 F652_2795
YIN: CH53_4238(dlgD)
YMA: DA391_10455
SMAC: SMDB11_3331(dlgD)
SPE: Spro_3933
SRR: SerAS9_4139
SRL: SOD_c38930(dlgD)
SRY: M621_20900
SPLY: Q5A_020880(dlgD)
SRS: SerAS12_4140
SRA: SerAS13_4140
SLQ: M495_20535
SFW: WN53_21580
SFG: AV650_17370
SQU: E4343_20725
SNEM: NLX84_20500(yiaK)
SGRI: SGBXF1_04033(dlgD)
SSAR: SSARUM_003932(yiaK)
SFO: Z042_06785
RAH: Rahaq_1074
RACE: JHW33_22085(yiaK)
RAQ: Rahaq2_1145
RAA: Q7S_05145
ROX: BV494_00640 BV494_15210
RBON: QNM34_05475(yiaK)
SERA: Ser39006_020885 Ser39006_022675
SERQ: CWC46_20890 CWC46_22685
PCT: PC1_3692
PWA: Pecwa_3889
PPAR: A8F97_22060
PEC: W5S_4035
PWS: A7983_04500 A7983_12495 A7983_12510
PPUJ: E2566_18665
PARI: I2D83_03340(yiaK)
PAQU: DMB82_0017635(yiaK)
PQU: IG609_017415(yiaK)
PPOO: LW347_18720(yiaK)
PACB: M9782_06655(yiaK)
PARL: PEC302110_08100(yiaK)
BGJ: AWC36_17715
PROD: PCO85_02485(yiaK) PCO85_04565(yiaK)
SOD: Sant_1948
EPE: CI789_16640
ETP: LU633_19545(yiaK)
ERP: LJN55_21155(yiaK)
PAM: PANA_0364(dlgD)
PLF: PANA5342_4050(dlgD)
PAJ: PAJ_3520(dlgD)
PAQ: PAGR_g3913
PAO: Pat9b_1877
PSTW: DSJ_03410
PPHO: CTZ24_09875
TCI: A7K98_02595
EHO: A9798_02100
HAV: AT03_19190
HPAR: AL518_07400 AL518_10545
OPO: DSM2777_06205
HIN: HI_1031
HIQ: CGSHiGG_08775
HPAK: JT17_07790
HSO: HS_0759(mdh)
HSM: HSM_1226
PMU: PM1256
PMV: PMCN06_1920(dlgD)
PUL: NT08PM_2210
PMP: Pmu_19160(dlgD)
PMUL: DR93_499(dlgD)
PDAG: 4362423_01625(dlgD)
PSKY: A6B44_10495
PATL: KGI96_10570(yiaK)
PCAI: K7G93_001845(yiaK)
MSU: MS0054
BSUN: A4G13_09070
MHT: D648_390
MHQ: D650_370
MHAT: B824_1140
MHX: MHH_c05720(dlgD)
MHAE: F382_07945
MHAM: J450_07145
MHAO: J451_08025
MHAL: N220_00120
MHAQ: WC39_00180
MHAY: VK67_00185
MVR: X781_670
MVI: X808_820
MVG: X874_790
MVE: X875_20260
MGRA: A4G16_09800
MBOS: ICJ55_02005(yiaK)
MPEG: HV560_02710(yiaK)
MANN: GM695_02540
APL: APL_1573
APJ: APJL_1604 APJL_1605
APA: APP7_1635
ASU: Asuc_0268
ASI: ASU2_10040
ASS: ASU1_10085
AEU: ACEE_10335
APOR: DDU33_01580
ALIG: NCTC10568_01932(dlgD)
AGP: NYR63_08455(yiaK)
AGK: NYR60_07035(yiaK)
GSS: NYR30_10705(yiaK)
BTO: WQG_22320
BTRE: F542_290
BTRH: F543_300
BTRA: F544_22850
RPNE: NCTC8284_03314(dlgD_2)
RHEY: FEE42_11320
RHAE: IHV77_10320(yiaK)
OOI: A6A10_00695 A6A10_00745
FCL: A4G17_03000
BHUD: A6A11_09075
PAET: NCTC13378_00072(dlgD)
VSP: VS_II0146
VGA: BSQ33_11610
VSH: BSZ05_18275
VSR: Vspart_00567(dlgD)
VLE: ISX51_21815(yiaK)
VRU: RND59_03335(yiaK)
MKE: OOT55_06440(yiaK)
HHU: AR456_18335
HPRO: LMS44_04965(yiaK)
HBH: E4T21_20090(yiaK)
HALF: QEN58_04320(yiaK)
HAAH: HALA3H3_50019(dlgD)
HOL: HORIV_15110(dlgD)
HNP: SR894_04265(yiaK)
HTT: HZS52_23275(yiaK)
HAA: A5892_03140
KUS: B9G99_15925
KMA: B9H00_15710
MARS: A8C75_18935
BCT: GEM_3243
BPYR: ABD05_23400
BANN: JFN94_16455(yiaK)
BURK: DM992_23800
PTS: CUJ90_31490
MARU: FIU81_09120(dlgD)
PZH: CX676_12965
PARO: CUV01_08870
OCN: CUC15_16400
NCM: QNK12_13515(yiaK)
PHEX: L0M14_06415(yiaK)
SPAE: E2C16_10285
CBEI: LF65_03926
CPAS: Clopa_1614
CPAT: CLPA_c27020(dlgD)
CPAE: CPAST_c27020(dlgD)
CEU: A7L45_01920
FTK: PXT33_010115(yiaK)
ALKA: J0B03_03745(yiaK) J0B03_03860(yiaK)
BLIQ: INP51_13510(yiaK)
CPY: Cphy_1597
LACY: A4V08_05145 A4V08_19720 A4V08_26375
LXA: OW255_01530(yiaK)
RGN: RGna_04580
CBOL: CGC65_17835 CGC65_28090
CASP: NQ535_05220(yiaK) NQ535_09435(yiaK) NQ535_23280(yiaK)
DFM: NQ560_12490(yiaK)
QDO: H9Q78_10435(yiaK)
MFOR: NQ534_12200(yiaK)
CBAR: PATL70BA_2571(yiaK)
GFE: Gferi_07860
HALS: D7D81_01315
IFN: GM661_17375
APR: Apre_0576
MHAP: JFY71_00655(yiaK)
PUF: UFO1_3871
ERB: A4V01_00980
APAL: BN85403770
GEZ: FE251_05235
SLOM: PXH66_21015(yiaK)
TPAV: HRQ91_07735(yiaK)
SBU: SpiBuddy_2240
SGP: SpiGrapes_1800 SpiGrapes_2576
SASS: MUG09_12345(yiaK) MUG09_13745(yiaK)
ACA: ACP_1954
ACM: AciX9_1752
GMA: AciX8_0342
GRB: GOB94_08635
TSA: AciPR4_0567
TALB: FTW19_15705
EDA: GWR55_06525(yiaK)
EDG: H7846_13235(yiaK)
ORP: MOP44_12565(yiaK)
TEMP: RBB75_16235(yiaK)
PFER: IRI77_25355(yiaK)
GBA: J421_0713
DRC: G0Q07_19910(yiaK)
MCOS: GM418_15300
ANF: AQPE_3768
CHF: KTO58_24915(yiaK)
CSAC: SIO70_18050(yiaK)
CHIM: CK934_03855
NKO: Niako_3650
FGG: FSB75_04805
HHY: Halhy_6468
PHE: Phep_3438
PGS: CPT03_01000
PEJ: FYC62_04300
PSN: Pedsa_2698
MUP: A0256_23975
MUC: MuYL_3799
MGOT: MgSA37_04096(dlgD)
MUH: HYN43_028665
MGIN: FRZ54_22780
MGK: FSB76_05645
MRUB: DEO27_030395
MGOS: DIU38_032655
MMAB: HQ865_17775(yiaK)
MDJ: LLH06_05880(yiaK)
MJJ: PQO05_04185(yiaK)
MSAB: SNE25_06615(yiaK)
CMR: Cycma_3367
CAMU: CA2015_3203
EVI: Echvi_3091
EST: DN752_22295
ECHI: FKX85_14620
EMAI: KZP23_19675(yiaK)
RHOZ: GXP67_33145(yiaK)
PSEZ: HME7025_02598(dpkA)
EOL: Emtol_1032
RSI: Runsl_5467
RUP: DTQ70_01990
FIB: A6C57_03190
HYZ: AXW84_03380
HYJ: FHG12_13530
PKO: PKOR_07140
PACT: CA264_18075
PONT: C1N53_18440
RUF: TH63_05215
CLIT: OQ292_23085(yiaK)
IRO: RT717_14585(yiaK)
FBT: D770_00610
CHK: D4L85_18090
MARM: YQ22_10005
MART: BTR34_10075
MARE: EJ994_10305
SEON: BWZ22_15620
AALG: AREALGSMS7_03762(dlgD)
MARF: CJ739_2488
EMAR: D1013_18825
ASAG: FGM00_11440
RBAR: AWN76_004040
MRO: MROS_2339
 » show all
Reference
PMID:11741871
  Authors
Yew WS, Gerlt JA.
  Title
Utilization of L-ascorbate by Escherichia coli K-12: assignments of functions to products of the yjf-sga and yia-sgb operons.
  Journal
J Bacteriol 184:302-6 (2002)
DOI:10.1128/JB.184.1.302-306.2002
LinkDB

KEGG   ENZYME: 1.1.1.130
Entry
EC 1.1.1.130                Enzyme                                 
Name
3-dehydro-L-gulonate 2-dehydrogenase;
3-keto-L-gulonate dehydrogenase;
3-ketogulonate dehydrogenase;
3-keto-L-gulonate dehydrogenase;
3-ketogulonate dehydrogenase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
3-dehydro-L-gulonate:NAD(P)+ 2-oxidoreductase
Reaction(IUBMB)
3-dehydro-L-gulonate + NAD(P)+ = (4R,5S)-4,5,6-trihydroxy-2,3-dioxohexanoate + NAD(P)H + H+ [RN:R02637 R02639]
Reaction(KEGG)
R02637 R02639
Substrate
3-dehydro-L-gulonate [CPD:C00618];
NAD+ [CPD:C00003];
NADP+ [CPD:C00006]
Product
(4R,5S)-4,5,6-trihydroxy-2,3-dioxohexanoate [CPD:C04575];
NADH [CPD:C00004];
NADPH [CPD:C00005];
H+ [CPD:C00080]
History
EC 1.1.1.130 created 1972
Pathway
ec00040  Pentose and glucuronate interconversions
ec00053  Ascorbate and aldarate metabolism
ec01100  Metabolic pathways
Orthology
K08092  3-dehydro-L-gulonate 2-dehydrogenase
Genes
ECO: b3575(yiaK)
ECJ: JW3547(yiaK)
ECD: ECDH10B_3756(yiaK)
EBW: BWG_3265(yiaK)
ECOK: ECMDS42_3012(yiaK)
ECOC: C3026_19385
EOI: ECO111_4395(yiaK)
EOJ: ECO26_5026(yiaK)
EOH: ECO103_4659(yiaK)
ESL: O3K_00975
ESO: O3O_24700
ESM: O3M_01005
ECK: EC55989_4032(yiaK)
ECG: E2348C_3827(yiaK)
ELH: ETEC_3818
ECW: EcE24377A_4072(dlgD)
EUN: UMNK88_4360
ECP: ECP_3679
ENA: ECNA114_3727(yiaK)
ECOS: EC958_3982(yiaK)
ECV: APECO1_2875(yiaK)
ECOA: APECO78_21690
ECX: EcHS_A3779(dlgD)
ECM: EcSMS35_3898(dlgD)
ECY: ECSE_3851
ECR: ECIAI1_3742(yiaK)
ECQ: ECED1_4263(yiaK)
EUM: ECUMN_4088(yiaK)
ECT: ECIAI39_4087(yiaK)
EOC: CE10_4129(yiaK)
EBR: ECB_03427(yiaK)
ECOB: C3029_21970
EBL: ECD_03427(yiaK)
EBE: B21_03378(yiaK)
EBD: ECBD_0159
ECI: UTI89_C4117(yiaK)
EIH: ECOK1_4022(dlgD)
ECZ: ECS88_3994(yiaK)
ECC: c4396(yiaK)
ELO: EC042_3881(dlgD)
ELN: NRG857_17800
ESE: ECSF_3410
ECL: EcolC_0139
EKO: EKO11_0151
EKF: KO11_04845(yiaK)
EAB: ECABU_c40180(dlgD)
EDH: EcDH1_0135
EDJ: ECDH1ME8569_3456(yiaK)
ELU: UM146_18045
ELW: ECW_m3849(yiaK)
ELL: WFL_18795(yiaK)
ELC: i14_4063(yiaK)
ELD: i02_4063(yiaK)
ELP: P12B_c3704(yiaK)
ELF: LF82_3339(yiaK)
ECOL: LY180_18385
ECOI: ECOPMV1_03913(dlgD)
ECOJ: P423_19890
EFE: EFER_3573(yiaK)
EAL: EAKF1_ch2371c
EMA: C1192_15920
ESZ: FEM44_09065
ERUY: OSH18_12085(yiaK)
STY: STY4130
STT: t3851
SEX: STBHUCCB_40640
SENT: TY21A_19565
STM: STM3668(yiaK)
SEO: STM14_4425(yiaK)
SEV: STMMW_36561
SEY: SL1344_3633(yiaK)
SEM: STMDT12_C37250
SEJ: STMUK_3654(yiaK)
SEB: STM474_3840(yiaK)
SEF: UMN798_3985
SETU: STU288_18530
SETC: CFSAN001921_22105
SENR: STMDT2_35521
SEND: DT104_36511
SENI: CY43_19040
SEEN: SE451236_02580
SPT: SPA3519(yiaK)
SEK: SSPA3286
SPQ: SPAB_04559
SEI: SPC_3748(yiaK)
SEH: SeHA_C3991
SHB: SU5_04145
SENH: CFSAN002069_13700
SEEH: SEEH1578_04425
SEE: SNSL254_A3946
SENN: SN31241_2150
SEW: SeSA_A3866
SEA: SeAg_B3882
SENS: Q786_17920
SED: SeD_A4053
SEG: SG3763(yiaK)
SEL: SPUL_3897(yiaK)
SEGA: SPUCDC_3883(yiaK)
SET: SEN3490(yiaK)
SENA: AU38_17830
SENO: AU37_18020
SENV: AU39_18025
SENQ: AU40_20080
SENL: IY59_18465
SENJ: CFSAN001992_15305
SEEC: CFSAN002050_25310
SEEB: SEEB0189_001535
SEEP: I137_18700
SENB: BN855_37560
SENE: IA1_17815
SENC: SEET0819_02100
SALZ: EOS98_00910
SFL: SF3619(yiaK)
SFX: S4150(yiaK)
SFV: SFV_3965(yiaK)
SFE: SFxv_3943(yiaK)
SFN: SFy_5156
SFS: SFyv_5232
SFT: NCTC1_03914(yiaK)
SBO: SBO_3583(yiaK)
SBC: SbBS512_E3947(dlgD)
SHQ: A0259_21705
ENC: ECL_00191
ENL: A3UG_00985
ECLG: EC036_01840
ECLE: ECNIH2_22595
ECLI: ECNIH5_21115
ECLX: LI66_21885
ECLY: LI62_23905
ECLO: ENC_47440
EHM: AB284_02935
EXF: BFV63_21225
ECLA: ECNIH3_21195
ECLC: ECR091_21125
EEC: EcWSU1_00160(dlgD)
ELG: BH714_15955
ECAN: CWI88_00910
ERN: BFV67_00725
ECLS: LI67_001705
ECHG: FY206_00880
ESH: C1N69_00775
EAS: Entas_0167
ENF: AKI40_2078(yiaK)
LNI: CWR52_11755
EBG: FAI37_05810
ENS: HWQ15_07205(yiaK)
ENK: LOC22_09765(yiaK)
EHU: D5067_0022360
EMOR: L6Y89_21365(yiaK)
EQU: OM418_00745(yiaK)
EPU: QVH39_00765(yiaK)
KPE: KPK_0166(dlgD)
KVD: KR75_07255
KOX: KOX_05675
KOE: A225_5605
KOY: J415_04080
KOM: HR38_04170
KOK: KONIH1_28205
KOC: AB185_08195
KQV: B8P98_00955
KLL: BJF97_27840
KLW: DA718_01050
KAR: LGL98_00900(yiaK)
KGR: JJJ10_00975(yiaK)
KPAS: LUW96_05610(yiaK)
KLC: K7H21_00915(yiaK)
KLM: BWI76_27080
REE: electrica_00162(dlgD)
ROR: RORB6_19620
RON: TE10_01345
RAO: DSD31_00925
CKO: CKO_05033
CFD: CFNIH1_05490
CBRA: A6J81_18070
CWE: CO701_22940
CFQ: C2U38_26735
CIF: AL515_00420
CIE: AN232_05315
CPAR: CUC49_18435
CITZ: E4Z61_17830
CARS: E1B03_25335
CIX: M4I31_00840(yiaK)
ESC: Entcl_0163
KLE: AO703_20620
KOR: AWR26_18130(yiaK)
KRD: A3780_06125
KOO: O9K67_17730(yiaK)
KOU: C0557_06555
KAS: KATP_01750(dlgD_1) KATP_21200(dlgD_2)
LAZ: A8A57_00930
LEF: LJPFL01_0151
LEW: DAI21_03610
BFT: MNO13_13410(yiaK)
BSEL: RHD99_07420(yiaK)
KIN: AB182_26300
PDZ: HHA33_03015(yiaK)
METY: MRY16398_01670(dlgD)
IZH: FEM41_13790
PSGC: G163CM_37550(dlgD)
SUPE: P0H77_01115(yiaK) P0H77_19615(yiaK)
EBF: D782_0150
EBC: C2U52_09105
EBB: F652_2161 F652_2795
YIN: CH53_4238(dlgD)
YMA: DA391_10455
SMAC: SMDB11_3331(dlgD)
SPE: Spro_3933
SRR: SerAS9_4139
SRL: SOD_c38930(dlgD)
SRY: M621_20900
SPLY: Q5A_020880(dlgD)
SRS: SerAS12_4140
SRA: SerAS13_4140
SLQ: M495_20535
SFW: WN53_21580
SFG: AV650_17370
SQU: E4343_20725
SNEM: NLX84_20500(yiaK)
SGRI: SGBXF1_04033(dlgD)
SSAR: SSARUM_003932(yiaK)
SFO: Z042_06785
RAH: Rahaq_1074
RACE: JHW33_22085(yiaK)
RAQ: Rahaq2_1145
RAA: Q7S_05145
ROX: BV494_00640 BV494_15210
RBON: QNM34_05475(yiaK)
SERA: Ser39006_020885 Ser39006_022675
SERQ: CWC46_20890 CWC46_22685
PCT: PC1_3692
PWA: Pecwa_3889
PPAR: A8F97_22060
PEC: W5S_4035
PWS: A7983_04500 A7983_12495 A7983_12510
PPUJ: E2566_18665
PARI: I2D83_03340(yiaK)
PAQU: DMB82_0017635(yiaK)
PQU: IG609_017415(yiaK)
PPOO: LW347_18720(yiaK)
PACB: M9782_06655(yiaK)
PARL: PEC302110_08100(yiaK)
BGJ: AWC36_17715
PROD: PCO85_02485(yiaK) PCO85_04565(yiaK)
SOD: Sant_1948
EPE: CI789_16640
ETP: LU633_19545(yiaK)
ERP: LJN55_21155(yiaK)
PAM: PANA_0364(dlgD)
PLF: PANA5342_4050(dlgD)
PAJ: PAJ_3520(dlgD)
PAQ: PAGR_g3913
PAO: Pat9b_1877
PSTW: DSJ_03410
PPHO: CTZ24_09875
TCI: A7K98_02595
EHO: A9798_02100
HAV: AT03_19190
HPAR: AL518_07400 AL518_10545
OPO: DSM2777_06205
HIN: HI_1031
HIQ: CGSHiGG_08775
HPAK: JT17_07790
HSO: HS_0759(mdh)
HSM: HSM_1226
PMU: PM1256
PMV: PMCN06_1920(dlgD)
PUL: NT08PM_2210
PMP: Pmu_19160(dlgD)
PMUL: DR93_499(dlgD)
PDAG: 4362423_01625(dlgD)
PSKY: A6B44_10495
PATL: KGI96_10570(yiaK)
PCAI: K7G93_001845(yiaK)
MSU: MS0054
BSUN: A4G13_09070
MHT: D648_390
MHQ: D650_370
MHAT: B824_1140
MHX: MHH_c05720(dlgD)
MHAE: F382_07945
MHAM: J450_07145
MHAO: J451_08025
MHAL: N220_00120
MHAQ: WC39_00180
MHAY: VK67_00185
MVR: X781_670
MVI: X808_820
MVG: X874_790
MVE: X875_20260
MGRA: A4G16_09800
MBOS: ICJ55_02005(yiaK)
MPEG: HV560_02710(yiaK)
MANN: GM695_02540
APL: APL_1573
APJ: APJL_1604 APJL_1605
APA: APP7_1635
ASU: Asuc_0268
ASI: ASU2_10040
ASS: ASU1_10085
AEU: ACEE_10335
APOR: DDU33_01580
ALIG: NCTC10568_01932(dlgD)
AGP: NYR63_08455(yiaK)
AGK: NYR60_07035(yiaK)
GSS: NYR30_10705(yiaK)
BTO: WQG_22320
BTRE: F542_290
BTRH: F543_300
BTRA: F544_22850
RPNE: NCTC8284_03314(dlgD_2)
RHEY: FEE42_11320
RHAE: IHV77_10320(yiaK)
OOI: A6A10_00695 A6A10_00745
FCL: A4G17_03000
BHUD: A6A11_09075
PAET: NCTC13378_00072(dlgD)
VSP: VS_II0146
VGA: BSQ33_11610
VSH: BSZ05_18275
VSR: Vspart_00567(dlgD)
VLE: ISX51_21815(yiaK)
VRU: RND59_03335(yiaK)
MKE: OOT55_06440(yiaK)
HHU: AR456_18335
HPRO: LMS44_04965(yiaK)
HBH: E4T21_20090(yiaK)
HALF: QEN58_04320(yiaK)
HAAH: HALA3H3_50019(dlgD)
HOL: HORIV_15110(dlgD)
HNP: SR894_04265(yiaK)
HTT: HZS52_23275(yiaK)
HAA: A5892_03140
KUS: B9G99_15925
KMA: B9H00_15710
MARS: A8C75_18935
BCT: GEM_3243
BPYR: ABD05_23400
BANN: JFN94_16455(yiaK)
BURK: DM992_23800
PTS: CUJ90_31490
MARU: FIU81_09120(dlgD)
PZH: CX676_12965
PARO: CUV01_08870
OCN: CUC15_16400
NCM: QNK12_13515(yiaK)
PHEX: L0M14_06415(yiaK)
SPAE: E2C16_10285
CBEI: LF65_03926
CPAS: Clopa_1614
CPAT: CLPA_c27020(dlgD)
CPAE: CPAST_c27020(dlgD)
CEU: A7L45_01920
FTK: PXT33_010115(yiaK)
ALKA: J0B03_03745(yiaK) J0B03_03860(yiaK)
BLIQ: INP51_13510(yiaK)
CPY: Cphy_1597
LACY: A4V08_05145 A4V08_19720 A4V08_26375
LXA: OW255_01530(yiaK)
RGN: RGna_04580
CBOL: CGC65_17835 CGC65_28090
CASP: NQ535_05220(yiaK) NQ535_09435(yiaK) NQ535_23280(yiaK)
DFM: NQ560_12490(yiaK)
QDO: H9Q78_10435(yiaK)
MFOR: NQ534_12200(yiaK)
CBAR: PATL70BA_2571(yiaK)
GFE: Gferi_07860
HALS: D7D81_01315
IFN: GM661_17375
APR: Apre_0576
MHAP: JFY71_00655(yiaK)
PUF: UFO1_3871
ERB: A4V01_00980
APAL: BN85403770
GEZ: FE251_05235
SLOM: PXH66_21015(yiaK)
TPAV: HRQ91_07735(yiaK)
SBU: SpiBuddy_2240
SGP: SpiGrapes_1800 SpiGrapes_2576
SASS: MUG09_12345(yiaK) MUG09_13745(yiaK)
ACA: ACP_1954
ACM: AciX9_1752
GMA: AciX8_0342
GRB: GOB94_08635
TSA: AciPR4_0567
TALB: FTW19_15705
EDA: GWR55_06525(yiaK)
EDG: H7846_13235(yiaK)
ORP: MOP44_12565(yiaK)
TEMP: RBB75_16235(yiaK)
PFER: IRI77_25355(yiaK)
GBA: J421_0713
DRC: G0Q07_19910(yiaK)
MCOS: GM418_15300
ANF: AQPE_3768
CHF: KTO58_24915(yiaK)
CSAC: SIO70_18050(yiaK)
CHIM: CK934_03855
NKO: Niako_3650
FGG: FSB75_04805
HHY: Halhy_6468
PHE: Phep_3438
PGS: CPT03_01000
PEJ: FYC62_04300
PSN: Pedsa_2698
MUP: A0256_23975
MUC: MuYL_3799
MGOT: MgSA37_04096(dlgD)
MUH: HYN43_028665
MGIN: FRZ54_22780
MGK: FSB76_05645
MRUB: DEO27_030395
MGOS: DIU38_032655
MMAB: HQ865_17775(yiaK)
MDJ: LLH06_05880(yiaK)
MJJ: PQO05_04185(yiaK)
MSAB: SNE25_06615(yiaK)
CMR: Cycma_3367
CAMU: CA2015_3203
EVI: Echvi_3091
EST: DN752_22295
ECHI: FKX85_14620
EMAI: KZP23_19675(yiaK)
RHOZ: GXP67_33145(yiaK)
PSEZ: HME7025_02598(dpkA)
EOL: Emtol_1032
RSI: Runsl_5467
RUP: DTQ70_01990
FIB: A6C57_03190
HYZ: AXW84_03380
HYJ: FHG12_13530
PKO: PKOR_07140
PACT: CA264_18075
PONT: C1N53_18440
RUF: TH63_05215
CLIT: OQ292_23085(yiaK)
IRO: RT717_14585(yiaK)
FBT: D770_00610
CHK: D4L85_18090
MARM: YQ22_10005
MART: BTR34_10075
MARE: EJ994_10305
SEON: BWZ22_15620
AALG: AREALGSMS7_03762(dlgD)
MARF: CJ739_2488
EMAR: D1013_18825
ASAG: FGM00_11440
RBAR: AWN76_004040
MRO: MROS_2339
 » show all
Reference
1  [PMID:13926592]
  Authors
VOLK WA, LARSEN JL.
  Title
beta-Keto-L-gulonic acid as an intermediate in the bacterial metabolism of ascorbic acid.
  Journal
J Biol Chem 237:2454-7 (1962)
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.130
IUBMB Enzyme Nomenclature: 1.1.1.130
ExPASy - ENZYME nomenclature database: 1.1.1.130
BRENDA, the Enzyme Database: 1.1.1.130
CAS: 37250-61-6
LinkDB

KEGG   REACTION: R02637
Entry
R02637                      Reaction                               
Name
3-dehydro-L-gulonate:NAD+ 2-oxidoreductase
Definition
3-Dehydro-L-gulonate + NAD+ <=> (4R,5S)-4,5,6-Trihydroxy-2,3-dioxohexanoate + NADH + H+
Equation
C00618 + C00003 <=> C04575 + C00004 + C00080
Comment
NADP+ (see R02639)
Reaction class
RC00001  C00003_C00004
RC00238  C00618_C04575
Enzyme
1.1.1.130
Pathway
rn00040  Pentose and glucuronate interconversions
rn00053  Ascorbate and aldarate metabolism
rn01100  Metabolic pathways
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.130
     R02637  3-Dehydro-L-gulonate + NAD+ <=> (4R,5S)-4,5,6-Trihydroxy-2,3-dioxohexanoate + NADH + H+
Orthology
K08092  3-dehydro-L-gulonate 2-dehydrogenase [EC:1.1.1.130]
Other DBs
RHEA: 21927
LinkDB

KEGG   REACTION: R02639
Entry
R02639                      Reaction                               
Name
3-dehydro-L-gulonate:NADP+ 2-oxidoreductase
Definition
3-Dehydro-L-gulonate + NADP+ <=> (4R,5S)-4,5,6-Trihydroxy-2,3-dioxohexanoate + NADPH + H+
Equation
C00618 + C00006 <=> C04575 + C00005 + C00080
Comment
NAD+ (see R02637)
Reaction class
RC00001  C00005_C00006
RC00238  C00618_C04575
Enzyme
1.1.1.130
Pathway
rn00040  Pentose and glucuronate interconversions
rn00053  Ascorbate and aldarate metabolism
rn01100  Metabolic pathways
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.130
     R02639  3-Dehydro-L-gulonate + NADP+ <=> (4R,5S)-4,5,6-Trihydroxy-2,3-dioxohexanoate + NADPH + H+
Orthology
K08092  3-dehydro-L-gulonate 2-dehydrogenase [EC:1.1.1.130]
Other DBs
RHEA: 21931
LinkDB

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