KEGG   ORTHOLOGY: K08100
Entry
K08100                      KO                                     
Symbol
E1.3.3.5
Name
bilirubin oxidase [EC:1.3.3.5]
Pathway
map00860  Porphyrin metabolism
map01110  Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00860 Porphyrin metabolism
    K08100  E1.3.3.5; bilirubin oxidase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.3  With oxygen as acceptor
    1.3.3.5  bilirubin oxidase
     K08100  E1.3.3.5; bilirubin oxidase
Other DBs
RN: R02394
COG: COG2132
GO: 0047705
Genes
QSU: 111984172
NCR: NCU05042
NTE: NEUTE1DRAFT149066(NEUTE1DRAFT_149066)
SMP: SMAC_07604
PAN: PODANS72p329 PODANSg1176
MGR: MGG_07500 MGG_08046 MGG_13764
NHE: NECHADRAFT_53105
VAL: VDBG_05807
VDA: VDAG_07741
CFJ: CFIO01_04795 CFIO01_05641 CFIO01_06031
 » show all
Reference
PMID:8360171
  Authors
Koikeda S, Ando K, Kaji H, Inoue T, Murao S, Takeuchi K, Samejima T
  Title
Molecular cloning of the gene for bilirubin oxidase from Myrothecium verrucaria and its expression in yeast.
  Journal
J Biol Chem 268:18801-9 (1993)
  Sequence
LinkDB

KEGG   ENZYME: 1.3.3.5
Entry
EC 1.3.3.5                  Enzyme                                 
Name
bilirubin oxidase;
bilirubin oxidase M-1
Class
Oxidoreductases;
Acting on the CH-CH group of donors;
With oxygen as acceptor
Sysname
bilirubin:oxygen oxidoreductase
Reaction(IUBMB)
2 bilirubin + O2 = 2 biliverdin + 2 H2O [RN:R02394]
Reaction(KEGG)
R02394
Substrate
bilirubin [CPD:C00486];
O2 [CPD:C00007]
Product
biliverdin [CPD:C00500];
H2O [CPD:C00001]
History
EC 1.3.3.5 created 1984
Pathway
ec00860  Porphyrin metabolism
ec01110  Biosynthesis of secondary metabolites
Orthology
K08100  bilirubin oxidase
Genes
QSU111984172
NCRNCU05042
NTENEUTE1DRAFT149066(NEUTE1DRAFT_149066)
SMPSMAC_07604
PANPODANS72p329 PODANSg1176
MGRMGG_07500 MGG_08046 MGG_13764
NHENECHADRAFT_53105
VALVDBG_05807
VDAVDAG_07741
CFJCFIO01_04795 CFIO01_05641 CFIO01_06031
SAPOSAPIO_CDS4629
ELAUCREL1_5115
PFYPFICI_11472 PFICI_12852
PSCOLY89DRAFT_736333
GLZGLAREA_04938 GLAREA_05194
PNOSNOG_04650 SNOG_08624
PTEPTT_02572 PTT_08864
BZECOCCADRAFT_103567 COCCADRAFT_96914
BSCCOCSADRAFT_128720 COCSADRAFT_354546
BORCOCMIDRAFT_31664 COCMIDRAFT_88872
AALTCC77DRAFT_1097200 CC77DRAFT_933762
PFJMYCFIDRAFT_48579
BCOMBAUCODRAFT_35664
NPAUCRNP2_915
TMLGSTUM_00005793001
ADLAURDEDRAFT_129192 AURDEDRAFT_175769
 » show all
Reference
1
  Authors
Murao, S. and Tanaka, N.
  Title
A new enzyme bilirubin oxidase produced by Myrothecium verrucaria MT-1.
  Journal
Agric Biol Chem 45:2383-2384 (1981)
Reference
2
  Authors
Tanaka, N. and Murao, S.
  Title
Reaction of bilirubin oxidase produced by Myrothecium verrucaria MT-1. Agr.
  Journal
Biol Chem 49:843-844 (1985)
Other DBs
ExplorEnz - The Enzyme Database: 1.3.3.5
IUBMB Enzyme Nomenclature: 1.3.3.5
ExPASy - ENZYME nomenclature database: 1.3.3.5
BRENDA, the Enzyme Database: 1.3.3.5
CAS: 80619-01-8
LinkDB

KEGG   REACTION: R02394
Entry
R02394                      Reaction                               
Name
Bilirubin:oxygen oxidoreductase
Definition
2 Bilirubin + Oxygen <=> 2 Biliverdin + 2 H2O
Equation
2 C00486 + C00007 <=> 2 C00500 + 2 C00001
Reaction class
RC01983  C00486_C00500
Enzyme
Pathway
rn00860  Porphyrin metabolism
rn01110  Biosynthesis of secondary metabolites
Orthology
K08100  bilirubin oxidase [EC:1.3.3.5]
Other DBs
RHEA: 20983
LinkDB

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