KEGG   ORTHOLOGY: K08261
Entry
K08261                      KO                                     
Symbol
E1.1.99.21
Name
D-sorbitol dehydrogenase (acceptor) [EC:1.1.99.21]
Pathway
map00051  Fructose and mannose metabolism
map01100  Metabolic pathways
Reaction
R02925  D-sorbitol:(acceptor) 1-oxidoreductase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00051 Fructose and mannose metabolism
    K08261  E1.1.99.21; D-sorbitol dehydrogenase (acceptor)
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.99  With unknown physiological acceptors
    1.1.99.21  D-sorbitol dehydrogenase (acceptor)
     K08261  E1.1.99.21; D-sorbitol dehydrogenase (acceptor)
Other DBs
GO: 0047833
Genes
LCIC: INQ41_12750
GKD: K6Q96_22670
PLAS: NF212_20020
HAHH: O5O45_19925
CCAG: SR908_10730
HEL: HELO_2488
HBH: E4T21_18355
HADN: NKF27_17620
HCK: MRB56_20225
HSX: HNO51_06360
HTX: EKK97_07475
HSV: HNO53_07010
COBE: CLAM6_11490
COBB: H2O77_05980
SAJS: QO259_13090
CRZ: D1345_14600
CHAE: CH06BL_30710
AQS: DKK66_17340
RSO: RSc2147(sorD)
RSE: F504_2103
RPU: CDC45_10950
RNC: GO999_06140
BMA: BMA0330
BMV: BMASAVP1_A0628
BML: BMA10229_A2462
BMN: BMA10247_0076
BMAZ: BM44_2898(polS)
BMAL: DM55_1725(polS)
BMAE: DM78_269(polS)
BMAQ: DM76_1701(polS)
BMAI: DM57_2356
BMAF: DM51_125
BMAB: BM45_648
BPS: BPSL0826
BPM: BURPS1710b_1031(sdh)
BPL: BURPS1106A_0872
BPD: BURPS668_0868
BPR: GBP346_A0797
BPSE: BDL_1201(polS)
BPSM: BBQ_2622(polS)
BPSU: BBN_2745(polS)
BPSD: BBX_3148(polS)
BPZ: BP1026B_I2725
BPQ: BPC006_I0862
BPK: BBK_680(polS)
BPSH: DR55_294(polS)
BPSA: BBU_1354(polS)
BPSO: X996_3376(polS)
BUT: X994_1910
BTE: BTH_I0692
BTQ: BTQ_710(polS)
BTJ: BTJ_1734(polS)
BTZ: BTL_3012(polS)
BTD: BTI_2995(polS)
BTV: BTHA_3229(polS)
BTHE: BTN_1700(polS)
BTHM: BTRA_3324(polS)
BTHA: DR62_1887
BTHL: BG87_3204
BOK: DM82_218(polS)
BOC: BG90_806
BUU: WS70_04135
BSAV: WS86_14845
BHG: I6G56_05195
BUD: AQ610_14985
BVI: Bcep1808_2712
BVE: AK36_1310
BUR: Bcep18194_A5929
BCM: Bcenmc03_2622
BCH: Bcen2424_2598
BCJ: BCAL2811
BCEN: DM39_2682(polS)
BCEW: DM40_229(polS)
BCEO: I35_2668
BAM: Bamb_2646
BAC: BamMC406_2514
BMJ: BMULJ_02561(gutB)
BMU: Bmul_0699
BMK: DM80_2367(polS)
BMUL: NP80_2739
BCT: GEM_0835
BCED: DM42_2471(polS)
BDL: AK34_491
BPYR: ABD05_03035
BCON: NL30_26060
BUB: BW23_2296
BSEM: WJ12_13020
BSTG: WT74_13805
BANN: JFN94_13330
BARI: NLX30_15180
BAEN: L3V59_14940
BSER: R0290_13315
BGL: bglu_1g29520
BGU: KS03_403
BUG: BC1001_2896
BGF: BC1003_2832
BGD: bgla_1g32960
BGO: BM43_795(polS)
BUK: MYA_2359
BUL: BW21_3137
BGP: BGL_1c30960
BPLA: bpln_1g29980
BURK: DM992_06980
BURT: BTHE68_05030
BURM: GJG85_13795
BURF: Bsp3421_005297
BUV: FPJ27_33520
BXE: Bxe_A0719
BPH: Bphy_0489
BGE: BC1002_2507
BPY: Bphyt_3247
PMEG: FNZ07_29835
PTRO: G5S35_11685
PGIS: I6I06_15175
PACP: FAZ97_11465
PACS: FAZ98_11115
PEW: KZJ38_20075
PDIO: PDMSB3_3649(polS)
PBRY: NDK50_17325
PSAA: QEN71_02585
PKF: RW095_31880
PPAI: E1956_06045
PHUN: U0042_21860
PLAD: PPGU16_05250
PAZZ: PBP221_05090
CABA: SBC2_06780(polS_1)
CABK: NK8_05700
TVL: FAZ95_03805
TCAR: U0034_13500
RHOF: AB3G31_03190
ASAH: AVXHC19_09510
AAA: Acav_0908
VAP: Vapar_1113
VPE: Varpa_1196
VAZ: H7F35_18055
VAV: IG196_03955
VAE: RZE79_05125
VAX: H7F36_09785
VAW: SFB74_06430
RUG: QC826_00045
GLC: JQN73_19105
ETB: N7L95_14670
RLE: RL0650
RLT: Rleg2_0269
RLG: Rleg_0298
RLS: HB780_11275
RAW: NE851_13235
RLW: RlegWSM1455_01400
ARA: Arad_8191(smoS)
RBW: RLCC275e_01360
RIF: U5G49_000283
RHIZ: QMO80_001953
RBIN: PO860_01355
XDI: EZH22_02050
PLCG: RVY76_16180
AMAQ: GO499_03780
LCK: HN018_04230
MTAR: DF168_00276(polS_1)
SING: V5E97_25930
MCOS: GM418_25875
BHUI: LOK74_11095
BRUM: NDK47_23200
PBK: Back11_55830(fabG_8)
FFE: LSG31_22890
MSEO: MSEO_20530
SLON: LGI35_01325
KPUR: ACFCLZ_01435
MSUF: KV394_06850
PSOI: PCC79_06830
ARHD: VSH64_28420
LMAJ: GKN94_03605
HALR: EFA46_011410
HSAL: JMJ58_23290
 » show all
LinkDB

KEGG   ENZYME: 1.1.99.21
Entry
EC 1.1.99.21                Enzyme                                 
Name
D-sorbitol dehydrogenase (acceptor);
D-sorbitol:(acceptor) 1-oxidoreductase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With unknown physiological acceptors
Sysname
D-sorbitol:acceptor 1-oxidoreductase
Reaction(IUBMB)
D-sorbitol + acceptor = L-sorbose + reduced acceptor [RN:R01697]
Reaction(KEGG)
R01697 > R02925
Substrate
D-sorbitol [CPD:C00794];
acceptor [CPD:C00028]
Product
L-sorbose [CPD:C00247];
reduced acceptor [CPD:C00030]
Comment
A flavoprotein (FAD).
History
EC 1.1.99.21 created 1989
Pathway
ec00051  Fructose and mannose metabolism
ec01100  Metabolic pathways
Orthology
K08261  D-sorbitol dehydrogenase (acceptor)
Genes
LCIC: INQ41_12750
GKD: K6Q96_22670
PLAS: NF212_20020
HAHH: O5O45_19925
CCAG: SR908_10730
HEL: HELO_2488
HBH: E4T21_18355
HADN: NKF27_17620
HCK: MRB56_20225
HSX: HNO51_06360
HTX: EKK97_07475
HSV: HNO53_07010
COBE: CLAM6_11490
COBB: H2O77_05980
SAJS: QO259_13090
CRZ: D1345_14600
CHAE: CH06BL_30710
AQS: DKK66_17340
RSO: RSc2147(sorD)
RSE: F504_2103
RPU: CDC45_10950
RNC: GO999_06140
BMA: BMA0330
BMV: BMASAVP1_A0628
BML: BMA10229_A2462
BMN: BMA10247_0076
BMAZ: BM44_2898(polS)
BMAL: DM55_1725(polS)
BMAE: DM78_269(polS)
BMAQ: DM76_1701(polS)
BMAI: DM57_2356
BMAF: DM51_125
BMAB: BM45_648
BPS: BPSL0826
BPM: BURPS1710b_1031(sdh)
BPL: BURPS1106A_0872
BPD: BURPS668_0868
BPR: GBP346_A0797
BPSE: BDL_1201(polS)
BPSM: BBQ_2622(polS)
BPSU: BBN_2745(polS)
BPSD: BBX_3148(polS)
BPZ: BP1026B_I2725
BPQ: BPC006_I0862
BPK: BBK_680(polS)
BPSH: DR55_294(polS)
BPSA: BBU_1354(polS)
BPSO: X996_3376(polS)
BUT: X994_1910
BTE: BTH_I0692
BTQ: BTQ_710(polS)
BTJ: BTJ_1734(polS)
BTZ: BTL_3012(polS)
BTD: BTI_2995(polS)
BTV: BTHA_3229(polS)
BTHE: BTN_1700(polS)
BTHM: BTRA_3324(polS)
BTHA: DR62_1887
BTHL: BG87_3204
BOK: DM82_218(polS)
BOC: BG90_806
BUU: WS70_04135
BSAV: WS86_14845
BHG: I6G56_05195
BUD: AQ610_14985
BVI: Bcep1808_2712
BVE: AK36_1310
BUR: Bcep18194_A5929
BCM: Bcenmc03_2622
BCH: Bcen2424_2598
BCJ: BCAL2811
BCEN: DM39_2682(polS)
BCEW: DM40_229(polS)
BCEO: I35_2668
BAM: Bamb_2646
BAC: BamMC406_2514
BMJ: BMULJ_02561(gutB)
BMU: Bmul_0699
BMK: DM80_2367(polS)
BMUL: NP80_2739
BCT: GEM_0835
BCED: DM42_2471(polS)
BDL: AK34_491
BPYR: ABD05_03035
BCON: NL30_26060
BUB: BW23_2296
BSEM: WJ12_13020
BSTG: WT74_13805
BANN: JFN94_13330
BARI: NLX30_15180
BAEN: L3V59_14940
BSER: R0290_13315
BGL: bglu_1g29520
BGU: KS03_403
BUG: BC1001_2896
BGF: BC1003_2832
BGD: bgla_1g32960
BGO: BM43_795(polS)
BUK: MYA_2359
BUL: BW21_3137
BGP: BGL_1c30960
BPLA: bpln_1g29980
BURK: DM992_06980
BURT: BTHE68_05030
BURM: GJG85_13795
BURF: Bsp3421_005297
BUV: FPJ27_33520
BXE: Bxe_A0719
BPH: Bphy_0489
BGE: BC1002_2507
BPY: Bphyt_3247
PMEG: FNZ07_29835
PTRO: G5S35_11685
PGIS: I6I06_15175
PACP: FAZ97_11465
PACS: FAZ98_11115
PEW: KZJ38_20075
PDIO: PDMSB3_3649(polS)
PBRY: NDK50_17325
PSAA: QEN71_02585
PKF: RW095_31880
PPAI: E1956_06045
PHUN: U0042_21860
PLAD: PPGU16_05250
PAZZ: PBP221_05090
CABA: SBC2_06780(polS_1)
CABK: NK8_05700
TVL: FAZ95_03805
TCAR: U0034_13500
RHOF: AB3G31_03190
ASAH: AVXHC19_09510
AAA: Acav_0908
VAP: Vapar_1113
VPE: Varpa_1196
VAZ: H7F35_18055
VAV: IG196_03955
VAE: RZE79_05125
VAX: H7F36_09785
VAW: SFB74_06430
RUG: QC826_00045
GLC: JQN73_19105
ETB: N7L95_14670
RLE: RL0650
RLT: Rleg2_0269
RLG: Rleg_0298
RLS: HB780_11275
RAW: NE851_13235
RLW: RlegWSM1455_01400
ARA: Arad_8191(smoS)
RBW: RLCC275e_01360
RIF: U5G49_000283
RHIZ: QMO80_001953
RBIN: PO860_01355
XDI: EZH22_02050
PLCG: RVY76_16180
AMAQ: GO499_03780
LCK: HN018_04230
MTAR: DF168_00276(polS_1)
SING: V5E97_25930
MCOS: GM418_25875
BHUI: LOK74_11095
BRUM: NDK47_23200
PBK: Back11_55830(fabG_8)
FFE: LSG31_22890
MSEO: MSEO_20530
SLON: LGI35_01325
KPUR: ACFCLZ_01435
MSUF: KV394_06850
PSOI: PCC79_06830
ARHD: VSH64_28420
LMAJ: GKN94_03605
HALR: EFA46_011410
HSAL: JMJ58_23290
 » show all
Reference
1
  Authors
Shinagawa E, Ameyama M.
  Title
Purification and characterization of D-sorbitol dehydrogenase from membrane of Gluconobacter suboxydans var-alpha.
  Journal
Agric Biol Chem 46:135-141 (1982)
Other DBs
ExplorEnz - The Enzyme Database: 1.1.99.21
IUBMB Enzyme Nomenclature: 1.1.99.21
ExPASy - ENZYME nomenclature database: 1.1.99.21
BRENDA, the Enzyme Database: 1.1.99.21
CAS: 86178-94-1
LinkDB

KEGG   REACTION: R02925
Entry
R02925                      Reaction                               
Name
D-sorbitol:(acceptor) 1-oxidoreductase
Definition
D-Sorbitol + FAD <=> FADH2 + L-Sorbose
Equation
C00794 + C00016 <=> C01352 + C00247
Reaction class
RC00102  C00247_C00794
RC00126  C00016_C01352
Enzyme
1.1.99.21
Pathway
rn00051  Fructose and mannose metabolism
rn01100  Metabolic pathways
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.1  Acting on the CH-OH group of donors
   1.1.99  With unknown physiological acceptors
    1.1.99.21
     R02925  D-Sorbitol + FAD <=> FADH2 + L-Sorbose
IUBMB reaction hierarchy [BR:br08202]
 1. Oxidoreductase reactions
  1.1.99.21
   R01697  Acceptor <=> Reduced acceptor
    R02925  FAD <=> FADH2
Orthology
K08261  D-sorbitol dehydrogenase (acceptor) [EC:1.1.99.21]
LinkDB

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