KEGG   ORTHOLOGY: K08689
Entry
K08689                      KO                                     
Symbol
bphAa, bphA1, bphA
Name
biphenyl 2,3-dioxygenase subunit alpha [EC:1.14.12.18]
Pathway
map00621  Dioxin degradation
map01100  Metabolic pathways
map01120  Microbial metabolism in diverse environments
map01220  Degradation of aromatic compounds
Module
M00543  Biphenyl degradation, biphenyl => 2-oxopent-4-enoate + benzoate
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00621 Dioxin degradation
    K08689  bphAa, bphA1, bphA; biphenyl 2,3-dioxygenase subunit alpha
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.12  With NADH or NADPH as one donor, and incorporation of two atoms of oxygen into the other donor
    1.14.12.18  biphenyl 2,3-dioxygenase
     K08689  bphAa, bphA1, bphA; biphenyl 2,3-dioxygenase subunit alpha
Dioxygenases [br01602.html]
 Dioxygenases in aromatic ring cleavage
  K08689
Other DBs
RN: R05261 R05262 R05263 R05264 R05475
COG: COG4638
GO: 0018687
Genes
PSD: DSC_08755 DSC_09320
PFUW: KF707C_16330(bphA1)
PALL: UYA_07100
BXE: Bxe_C1197(bphA1)
BXB: DR64_8608(bphA)
PNA: Pnap_4152
ACK: C380_15925(bphA1)
CTES: O987_08255
ABRE: pbN1_20470
MAAD: AZF01_18230
CID: P73_0346
PGV: SL003B_4095(bphAa)
RHA: RHA1_ro08060(bphAa)
ROP: ROP_pROB02-01580(bnzA1)
AG: BAM76236(bphAa)
 » show all
Reference
PMID:7592331
  Authors
Haddock JD, Gibson DT
  Title
Purification and characterization of the oxygenase component of biphenyl 2,3-dioxygenase from Pseudomonas sp. strain LB400.
  Journal
J Bacteriol 177:5834-9 (1995)
DOI:10.1128/JB.177.20.5834-5839.1995
  Sequence
[bxe:Bxe_C1197]
Reference
  Authors
Vezina J, Barriault D, Sylvestre M
  Title
Family shuffling of soil DNA to change the regiospecificity of Burkholderia xenovorans LB400 biphenyl dioxygenase.
  Journal
J Bacteriol 189:779-88 (2007)
DOI:10.1128/JB.01267-06
LinkDB

KEGG   ORTHOLOGY: K15750
Entry
K15750                      KO                                     
Symbol
bphAb, bphA2, bphE
Name
biphenyl 2,3-dioxygenase subunit beta [EC:1.14.12.18]
Pathway
map00621  Dioxin degradation
map01100  Metabolic pathways
map01120  Microbial metabolism in diverse environments
map01220  Degradation of aromatic compounds
Module
M00543  Biphenyl degradation, biphenyl => 2-oxopent-4-enoate + benzoate
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00621 Dioxin degradation
    K15750  bphAb, bphA2, bphE; biphenyl 2,3-dioxygenase subunit beta
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.12  With NADH or NADPH as one donor, and incorporation of two atoms of oxygen into the other donor
    1.14.12.18  biphenyl 2,3-dioxygenase
     K15750  bphAb, bphA2, bphE; biphenyl 2,3-dioxygenase subunit beta
Dioxygenases [br01602.html]
 Dioxygenases in aromatic ring cleavage
  K15750
Other DBs
RN: R05261 R05262 R05263 R05264 R05475
GO: 0018687
Genes
PSD: DSC_08750
PFUW: KF707C_16320(bphA2)
BXE: Bxe_C1196(bphA2)
BXB: DR64_8609(bphE)
PNA: Pnap_4151
ACK: C380_15930(bphA2)
CTES: O987_08250
MAAD: AZF01_18225
CID: P73_0347
CON: TQ29_19175
PGV: SL003B_4096(bphAb)
RHA: RHA1_ro08059(bphAb)
ROP: ROP_pROB02-01590(bnzA2)
AG: BAM76237(bphAb)
 » show all
Reference
PMID:7592331
  Authors
Haddock JD, Gibson DT
  Title
Purification and characterization of the oxygenase component of biphenyl 2,3-dioxygenase from Pseudomonas sp. strain LB400.
  Journal
J Bacteriol 177:5834-9 (1995)
DOI:10.1128/JB.177.20.5834-5839.1995
  Sequence
[bxe:Bxe_C1196]
Reference
  Authors
Vezina J, Barriault D, Sylvestre M
  Title
Family shuffling of soil DNA to change the regiospecificity of Burkholderia xenovorans LB400 biphenyl dioxygenase.
  Journal
J Bacteriol 189:779-88 (2007)
DOI:10.1128/JB.01267-06
LinkDB

KEGG   ORTHOLOGY: K18087
Entry
K18087                      KO                                     
Symbol
bphAc, bphA3, bphF
Name
biphenyl 2,3-dioxygenase ferredoxin component
Pathway
map00621  Dioxin degradation
map01100  Metabolic pathways
map01120  Microbial metabolism in diverse environments
map01220  Degradation of aromatic compounds
Module
M00543  Biphenyl degradation, biphenyl => 2-oxopent-4-enoate + benzoate
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00621 Dioxin degradation
    K18087  bphAc, bphA3, bphF; biphenyl 2,3-dioxygenase ferredoxin component
Dioxygenases [br01602.html]
 Dioxygenases in aromatic ring cleavage
  K18087
Other DBs
RN: R05261 R05262 R05263 R05264 R05475
COG: COG2146
Genes
PSD: DSC_09340
PFUW: KF707C_16300(bphA3)
PALL: UYA_07085
BXE: Bxe_C1194(bphA3)
BXB: DR64_8611(bphA3)
PEW: KZJ38_26700
PNA: Pnap_4149
ACK: C380_15935(bphA3)
CTES: O987_08245
ABRE: pbN1_20500
CID: P73_0348
RHA: RHA1_ro08058(bphAc)
ROP: ROP_pROB02-01600(bnzA3)
AG: BAM76238(bphAc)
 » show all
Reference
PMID:1569021
  Authors
Erickson BD, Mondello FJ
  Title
Nucleotide sequencing and transcriptional mapping of the genes encoding biphenyl dioxygenase, a multicomponent polychlorinated-biphenyl-degrading enzyme in Pseudomonas strain LB400.
  Journal
J Bacteriol 174:2903-12 (1992)
DOI:10.1128/jb.174.9.2903-2912.1992
  Sequence
[bxe:Bxe_C1194]
LinkDB

KEGG   ORTHOLOGY: K18088
Entry
K18088                      KO                                     
Symbol
bphAd, bphA4, bphG
Name
biphenyl 2,3-dioxygenase ferredoxin reductase component [EC:1.18.1.3]
Pathway
map00621  Dioxin degradation
map01100  Metabolic pathways
map01120  Microbial metabolism in diverse environments
map01220  Degradation of aromatic compounds
Module
M00543  Biphenyl degradation, biphenyl => 2-oxopent-4-enoate + benzoate
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00621 Dioxin degradation
    K18088  bphAd, bphA4, bphG; biphenyl 2,3-dioxygenase ferredoxin reductase component
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.18  Acting on iron-sulfur proteins as donors
   1.18.1  With NAD+ or NADP+ as acceptor
    1.18.1.3  ferredoxin---NAD+ reductase
     K18088  bphAd, bphA4, bphG; biphenyl 2,3-dioxygenase ferredoxin reductase component
Dioxygenases [br01602.html]
 Dioxygenases in aromatic ring cleavage
  K18088
Other DBs
RN: R05261 R05262 R05263 R05264 R05475
COG: COG1251
GO: 0008860
Genes
PSD: DSC_09345
BANN: JFN94_18375
BXE: Bxe_C1193(bphA4)
BXB: DR64_8612(bedA)
PNA: Pnap_4148
RHA: RHA1_ro08057(bphAd)
ROP: ROP_pROB02-01610(bnzA4)
AG: BAM76239(bphAd)
Reference
PMID:1569021
  Authors
Erickson BD, Mondello FJ
  Title
Nucleotide sequencing and transcriptional mapping of the genes encoding biphenyl dioxygenase, a multicomponent polychlorinated-biphenyl-degrading enzyme in Pseudomonas strain LB400.
  Journal
J Bacteriol 174:2903-12 (1992)
DOI:10.1128/jb.174.9.2903-2912.1992
  Sequence
[bxe:Bxe_C1193]
LinkDB

KEGG   REACTION: R05263
Entry
R05263                      Reaction                               
Name
biphenyl,NADH2:oxygen oxidoreductase (2,3-hydroxylating)
Definition
Biphenyl + Oxygen + NADH + H+ <=> cis-2,3-Dihydro-2,3-dihydroxybiphenyl + NAD+
Equation
Reaction class
RC00001  C00003_C00004
RC00098  C06588_C06589
Enzyme
Pathway
rn00621  Dioxin degradation
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
rn01220  Degradation of aromatic compounds
Module
M00543  Biphenyl degradation, biphenyl => 2-oxopent-4-enoate + benzoate
Orthology
K08689  biphenyl 2,3-dioxygenase subunit alpha [EC:1.14.12.18]
K15750  biphenyl 2,3-dioxygenase subunit beta [EC:1.14.12.18]
K18087  biphenyl 2,3-dioxygenase ferredoxin component
K18088  biphenyl 2,3-dioxygenase ferredoxin reductase component [EC:1.18.1.3]
Other DBs
RHEA: 18168
LinkDB

KEGG   REACTION: R05264
Entry
R05264                      Reaction                               
Name
biphenyl,NADH:oxygen oxidoreductase (2,3-hydroxylating)
Definition
Biphenyl + Oxygen + NADPH + H+ <=> cis-2,3-Dihydro-2,3-dihydroxybiphenyl + NADP+
Equation
Reaction class
RC00001  C00005_C00006
RC00098  C06588_C06589
Enzyme
Pathway
rn00621  Dioxin degradation
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
rn01220  Degradation of aromatic compounds
Module
M00543  Biphenyl degradation, biphenyl => 2-oxopent-4-enoate + benzoate
Orthology
K08689  biphenyl 2,3-dioxygenase subunit alpha [EC:1.14.12.18]
K15750  biphenyl 2,3-dioxygenase subunit beta [EC:1.14.12.18]
K18087  biphenyl 2,3-dioxygenase ferredoxin component
K18088  biphenyl 2,3-dioxygenase ferredoxin reductase component [EC:1.18.1.3]
LinkDB

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