KEGG   ORTHOLOGY: K09753
Entry
K09753                      KO                                     
Symbol
CCR
Name
cinnamoyl-CoA reductase [EC:1.2.1.44]
Pathway
map00940  Phenylpropanoid biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00039  Monolignol biosynthesis, phenylalanine/tyrosine => monolignol
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00940 Phenylpropanoid biosynthesis
    K09753  CCR; cinnamoyl-CoA reductase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.1  With NAD+ or NADP+ as acceptor
    1.2.1.44  cinnamoyl-CoA reductase
     K09753  CCR; cinnamoyl-CoA reductase
Other DBs
RN: R01615 R01941 R02193 R02220 R02506 R06569
GO: 0016621
Genes
ATH: AT1G15950(CCR1) AT1G80820(CCR2)
ALY: 110224260 9326201
CRB: 17894897 17897690
CSAT: 104703349 104714287 104740281 104752432 104755910 104774803
EUS: EUTSA_v10008111mg EUTSA_v10018849mg
BRP: 103832452 103842872 103853214 103872395
BNA: 106346798 106354822 106367088 106381558 106396237 106414831 106429710 106430708
BOE: 106295555 106296937 106311455 106327709
RSZ: 108810958 108811215 108816249 108825600
THJ: 104812427 104813587 104826414
CPAP: 110824762
TCC: 18595421
GRA: 105768894
GAB: 108453575
EGR: 104423225
LJA: Lj3g3v0013390.1(Lj3g3v0013390.1) Lj3g3v2128240.1(Lj3g3v2128240.1) Lj3g3v2148260.1(Lj3g3v2148260.1)
FVE: 101302179
RCU: 8259741
JCU: 105630319
QSU: 112009904
QLO: 115991836
TWL: 120008035
VVI: 100251623
VRI: 117922518
SLY: 100125904(CCR1) 778359(CCR2)
EGT: 105972356
ECAD: 122588639
LSV: 111892196
CCAV: 112509602
BVG: 104904880
SOE: 110805090
DOSA: Os01t0283600-00(Os01g0283600) Os01t0283700-01(Os01g0283700) Os02t0180700-01(Os02g0180700) Os02t0808800-01(Os02g0808800) Os02t0811400-00(Os02g0811400) Os02t0811600-00(Os02g0811600) Os02t0811800-01(Os02g0811800) Os02t0812000-01(Os02g0812000) Os08t0277200-01(Os08g0277200) Os08t0441500-01(Os08g0441500) Os09t0127300-01(Os09g0127300) Os09t0262000-00(Os09g0262000) Os09t0419200-01(Os09g0419200)
DCT: 110093087
ATR: 18447024
 » show all
Reference
  Authors
Lauvergeat V, Lacomme C, Lacombe E, Lasserre E, Roby D, Grima-Pettenati J
  Title
Two cinnamoyl-CoA reductase (CCR) genes from Arabidopsis thaliana are differentially expressed during development and in response to infection with pathogenic bacteria.
  Journal
Phytochemistry 57:1187-95 (2001)
DOI:10.1016/s0031-9422(01)00053-x
  Sequence
LinkDB

KEGG   ENZYME: 1.2.1.44
Entry
EC 1.2.1.44                 Enzyme                                 
Name
cinnamoyl-CoA reductase;
feruloyl-CoA reductase;
cinnamoyl-coenzyme A reductase;
ferulyl-CoA reductase;
feruloyl coenzyme A reductase;
p-hydroxycinnamoyl coenzyme A reductase;
cinnamoyl-CoA:NADPH reductase
Class
Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With NAD+ or NADP+ as acceptor
Sysname
cinnamaldehyde:NADP+ oxidoreductase (CoA-cinnamoylating)
Reaction(IUBMB)
cinnamaldehyde + CoA + NADP+ = cinnamoyl-CoA + NADPH + H+ [RN:R02506]
Reaction(KEGG)
Substrate
cinnamaldehyde [CPD:C00903];
CoA [CPD:C00010];
NADP+ [CPD:C00006]
Product
cinnamoyl-CoA [CPD:C00540];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Comment
Acts also on a number of substituted cinnamoyl esters of coenzyme A.
History
EC 1.2.1.44 created 1978
Pathway
ec00940  Phenylpropanoid biosynthesis
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Orthology
K09753  cinnamoyl-CoA reductase
Genes
ATHAT1G15950(CCR1) AT1G80820(CCR2)
ALY110224260 9326201
CRB17894897 17897690
CSAT104703349 104714287 104740281 104752432 104755910 104774803
EUSEUTSA_v10008111mg EUTSA_v10018849mg
BRP103832452 103842872 103853214 103872395
BNA106346798 106354822 106367088 106381558 106396237 106414831 106429710 106430708
BOE106295555 106296937 106311455 106327709
RSZ108810958 108811215 108816249 108825600
THJ104812427 104813587 104826414
CPAP110824762
CIT102615114 102615391
CICCICLE_v10026007mg CICLE_v10026012mg
PVY116132019 116132020 116132533 116132534 116143362
MINC123206446 123206471 123209988 123210607 123210934 123218467 123218562
TCC18595421
GRA105768894
GHI107906426 107958455
GAB108453575
DZI111274390 111278784 111280911 111281115
EGR104423225
GMX100789070 100796771(CCR) 100799994 100811528
GSJ114376899 114386897 114418058 114422490
PVUPHAVU_005G182100g PHAVU_010G160700g
VRA106762574 106773575
VAR108320633 108334476
VUN114166279 114185415
CCAJ109812665 109812977
APRC113853999 113857169
MTRMTR_2g104960 MTR_4g006940
CAM101489660 101497779
LJALj3g3v0013390.1(Lj3g3v0013390.1) Lj3g3v2128240.1(Lj3g3v2128240.1) Lj3g3v2148260.1(Lj3g3v2148260.1)
ADU107459741 107463776
AIP107617648 107618046
AHF112703807 112709743 112773195 112776189
LANG109340430 109356075 109358362
FVE101302179
RCN112182362 112188461
PPER18782836 18783603 18784457
PMUM103328170 103328171 103328172 103328195
PAVI110763383 110763385
PDUL117620745 117621321 117621323 117622111 117622175
MDM103424888 103438772
PXB103945355 103945358 108867111
ZJU107408516 107408651 107408760 107409091 107425908
MNT21396681 21396683
CSV101213412 101218838 101219069 116401652 116401668
CMO103499837 103500289 103500290 103502823 103502824
BHJ120086819 120089690 120089691 120091358 120091417
MCHA111020774 111020985 111020994
CMAX111481542 111481543 111481544 111488801 111492576 111492719
CMOS111441436 111441477 111442011 111452574 111452626 111456058
CPEP111784197 111787891 111787892 111790043 111790089 111791124 111807103
RCU8259741
JCU105630319
HBR110640790 110641227 110641228
MESC110613289 110626824
POP18094264 18094265 18094536 18094540 7487057 7487058 7493223
PEU105119801 105122930 105132634 105132742
PALZ118034044 118034046 118034052 118034053 118034054 118034058 118034059 118034060 118053528 118053529 118053532 118054652
JRE109010062 109010995
QSU112009904
QLO115991836
TWL120008035
VVI100251623
VRI117922518
SLY100125904(CCR1) 778359(CCR2)
SPEN107012453 107023856
SOT102577453 102580211
SSTN125850024 125860017
CANN107861980 107861981 107876017 107878814
NTA107767921 107768715 107815050 107816628
NSY104211097 104214415
NTO104090926 104121164
NAU109218000 109223865
INI109162983 109164697 109164749 109191772
ITR115997617 116010329 116032631 116033296
SIND105158313 105165128
OEU111365297 111375374 111401874
EGT105972356
SSPL121746677 121750226
HAN110868781 110917450 110918543
ECAD122588639
LSV111892196
CCAV112509602
DCR108196096 108211420 108211933 108212209 108227809 108228129
CSIN114269014 114284668
BVG104904880
SOE110805090
CQI110684970 110739964
NNU104603320 104610717
MING122063370 122082290 122085760 122087711 122091216 122092737 122092787
TSS122646644 122649066 122652554 122653150
PSOM113310297 113315025 113321830 113329997 113330151
NCOL116250086 116253047
OSA4327908 4327909 4328509 4331085 4331101 4331102 4331103 4345156 4345689 4346438 4346551 4347074
DOSAOs01t0283600-00(Os01g0283600) Os01t0283700-01(Os01g0283700) Os02t0180700-01(Os02g0180700) Os02t0808800-01(Os02g0808800) Os02t0811400-00(Os02g0811400) Os02t0811600-00(Os02g0811600) Os02t0811800-01(Os02g0811800) Os02t0812000-01(Os02g0812000) Os08t0277200-01(Os08g0277200) Os08t0441500-01(Os08g0441500) Os09t0127300-01(Os09g0127300) Os09t0262000-00(Os09g0262000) Os09t0419200-01(Os09g0419200)
OBR102711504 102711778 102712056 102714947 102715891 102716196 102716621 102721008 102722421
BDI100822439 100822750 100823534 100823680 100831132 100831271 100832790 100840321
ATS109745831 109754250 109760091 109760092 109760607 109761766 109761768 109761769 109768977 109774003 109780729 109780731 109781309
TDC119297004 119297005 119297008 119298044 119301104 119301706 119305228 119305229 119305230 119308628 119309679 119311997 119311999 119314618 119314622 119314623 119314776 119316258 119318460 119322159 119324748 119325657 119325906 119326027 119326265 119327687 119339896 119339897
TAES100127082 123101614 123102338 123103319 123106597 123112098 123113481 123115732 123115733 123117055 123119527 123119528 123120738 123128924 123129792 123131297 123131300 123131303 123132474 123134969 123134972 123134973 123134975 123134986 123134987 123136544 123142124 123142127 123142130 123142143 123142749 123144051 123150180 123158330 123158355 123167495 123167496 542866 543055
TUA125508909 125509449 125512957 125512959 125512962 125512964 125512967 125521916 125529241 125531004
SBI110434137 8056422 8056423 8063428 8063719 8076207 8077848 8078129 8079406
ZMA100285564 100382657 103634692 103634693 103654125 109946031 542463 542735
SITA101755442 101756000 101756805 101757221 101761894 101763396 101779528 101784783 101785020
SVS117841515 117842918 117852760 117854857 117858418 117860566 117861494 117866344
PVIR120641267 120645913 120654849 120654851 120657571 120657572 120673417 120673500 120673639 120677484 120678047 120702575 120702837 120712484
PHAI112872776 112874714 112879317 112890951 112896402 112896712 112897181 112897193 112900472
PDA103702969 103710428 103714248 120107841
EGU105036005 105050729 105060184
MUS103970696 103970996 103983923
DCT110093087
PEQ110024447 110039326
AOF109841235 109843987 109844852
ATR18447024
SMOSELMODRAFT_123171 SELMODRAFT_134883 SELMODRAFT_134989 SELMODRAFT_227659 SELMODRAFT_227661 SELMODRAFT_228517 SELMODRAFT_228519 SELMODRAFT_234633 SELMODRAFT_450549(CCR1-1) SELMODRAFT_450552(CCR1-2) SELMODRAFT_85242
PPP112284247 112284670 112288176 112293893
NGRNAEGRDRAFT_45618
 » show all
Reference
1  [PMID:236926]
  Authors
Gross GG, Kreiten W.
  Title
Reduction of coenzyme A thioesters of cinnamic acids with an enzyme preparation from lignifying tissue of Forsythia.
  Journal
FEBS Lett 54:259-62 (1975)
DOI:10.1016/0014-5793(75)80087-1
Reference
2  [PMID:6365550]
  Authors
Sarni F, Grand C, Boudet AM.
  Title
Purification and properties of cinnamoyl-CoA reductase and cinnamyl alcohol dehydrogenase from poplar stems (Populus X euramericana).
  Journal
Eur J Biochem 139:259-65 (1984)
DOI:10.1111/j.1432-1033.1984.tb08002.x
Reference
3  [PMID:7454]
  Authors
Wengenmayer H, Ebel J, Grisebach H.
  Title
Enzymic synthesis of lignin precursors. Purification and properties of a cinnamoyl-CoA: NADPH reductase from cell suspension cultures of soybean (Glycinemax).
  Journal
Eur J Biochem 65:529-36 (1976)
DOI:10.1111/j.1432-1033.1976.tb10370.x
Other DBs
ExplorEnz - The Enzyme Database: 1.2.1.44
IUBMB Enzyme Nomenclature: 1.2.1.44
ExPASy - ENZYME nomenclature database: 1.2.1.44
BRENDA, the Enzyme Database: 1.2.1.44
CAS: 59929-39-4
LinkDB

KEGG   REACTION: R02220
Entry
R02220                      Reaction                               
Name
sinapoyl aldehyde:NADP+ oxidoreductase (CoA-sinapoylating)
Definition
Sinapoyl aldehyde + CoA + NADP+ <=> Sinapoyl-CoA + NADPH + H+
Equation
Reaction class
RC00001  C00005_C00006
RC00004  C00010_C00411
RC00566  C00411_C05610
Enzyme
Pathway
rn00940  Phenylpropanoid biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Orthology
K09753  cinnamoyl-CoA reductase [EC:1.2.1.44]
Other DBs
RHEA: 64659
LinkDB

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