Entry |
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Symbol |
HSD17B3
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Name |
testosterone 17beta-dehydrogenase (NADP+) [EC: 1.1.1.64]
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Pathway |
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Module |
M00976 | C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone |
M00977 | C19-Steroid hormone biosynthesis (androgen backdoor pathway), pregnenolone => androsterone => dihydrotestosterone |
|
Reaction |
R01838 | testosterone:NADP+ 17-oxidoreductase |
R13219 | androstan-3alpha,17beta-diol:NADP+ 17-oxidoreductase |
R13220 | dihydrotestosterone:NADP+ 17-oxidoreductase |
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Disease |
H00608 | 46,XY disorder of sex development due to testosterone secretion defect |
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Brite |
KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
K10207 HSD17B3; testosterone 17beta-dehydrogenase (NADP+)
Enzymes [BR:ko01000]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.64 testosterone 17beta-dehydrogenase (NADP+)
K10207 HSD17B3; testosterone 17beta-dehydrogenase (NADP+)
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Other DBs |
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Genes |
» show all
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Reference |
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Authors |
Andersson S, Moghrabi N |
Title |
Physiology and molecular genetics of 17 beta-hydroxysteroid dehydrogenases. |
Journal |
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Reference |
|
Authors |
Lukacik P, Kavanagh KL, Oppermann U |
Title |
Structure and function of human 17beta-hydroxysteroid dehydrogenases. |
Journal |
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LinkDB |
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