KEGG   ORTHOLOGY: K10217
Entry
K10217                      KO                                     
Symbol
dmpC, xylG, praB
Name
aminomuconate-semialdehyde/2-hydroxymuconate-6-semialdehyde dehydrogenase [EC:1.2.1.32 1.2.1.85]
Pathway
map00362  Benzoate degradation
map00380  Tryptophan metabolism
map00622  Xylene degradation
map01100  Metabolic pathways
map01120  Microbial metabolism in diverse environments
map01220  Degradation of aromatic compounds
Module
M00038  Tryptophan metabolism, tryptophan => kynurenine => 2-aminomuconate
M00569  Catechol meta-cleavage, catechol => acetyl-CoA / 4-methylcatechol => propanoyl-CoA
Reaction
R02762  2-hydroxymuconate semialdehyde:NAD+ 6-oxidoreductase
R03889  2-aminomuconate semialdehyde:NAD+ 6-oxidoreductase
R05353  2-hydroxy-5-methyl-cis,cis-muconic semialdehyde:NAD+ 6-oxidoreductase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00380 Tryptophan metabolism
    K10217  dmpC, xylG, praB; aminomuconate-semialdehyde/2-hydroxymuconate-6-semialdehyde dehydrogenase
  09111 Xenobiotics biodegradation and metabolism
   00362 Benzoate degradation
    K10217  dmpC, xylG, praB; aminomuconate-semialdehyde/2-hydroxymuconate-6-semialdehyde dehydrogenase
   00622 Xylene degradation
    K10217  dmpC, xylG, praB; aminomuconate-semialdehyde/2-hydroxymuconate-6-semialdehyde dehydrogenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.1  With NAD+ or NADP+ as acceptor
    1.2.1.32  aminomuconate-semialdehyde dehydrogenase
     K10217  dmpC, xylG, praB; aminomuconate-semialdehyde/2-hydroxymuconate-6-semialdehyde dehydrogenase
    1.2.1.85  2-hydroxymuconate-6-semialdehyde dehydrogenase
     K10217  dmpC, xylG, praB; aminomuconate-semialdehyde/2-hydroxymuconate-6-semialdehyde dehydrogenase
Other DBs
GO: 0047102
Genes
PGE: LG71_12245
SLQ: M495_05225
PROD: PCO85_03385
PSD: DSC_09155
PMEX: H4W19_03340
PJP: LAG73_06440
LAB: LA76x_2548(aldH8A1)
LAQ: GLA29479_1093
LCP: LC55x_2794(aldH8A1)
LGU: LG3211_2666(aldh8a1)
LEZ: GLE_2672
LEM: LEN_2363
LMB: C9I47_1501
LYT: DWG18_05815
LUE: DCD74_03960
LYJ: FKV23_07545
LSOL: GOY17_11460
LSX: H8B22_00640
LARE: HIV01_004055
LHX: LYSHEL_29980(hpaE)
LCAS: LYSCAS_29950(hpaE)
LCIC: INQ41_07790
LAVI: INQ42_07225
LLZ: LYB30171_01459(amnC)
LAUX: LA521A_22220
LYA: RDV84_19010
LSY: H8L67_00465
LSF: I8J32_011910
LUM: CNR27_08240
LUS: E5843_08240
LUG: FPZ22_13395
LFX: LU699_16000
LUJ: BGP89_12815
THES: FHQ07_01245
THEH: G7079_08025
TCN: H9L16_12765
TBV: H9L17_01795
THEX: ICG51_000383
XBC: ELE36_12500
FSG: LQ771_09720
FED: LQ772_10970
RHD: R2APBS1_1171
RGL: CS053_06000
RTH: LRK53_07370 LRK53_10265
DJI: CH75_03340
DJA: HY57_09330
DYE: EO087_08395
DCS: ISN74_04660
DTL: H8F01_15810
DTA: DYST_01720
DYG: DYGSA30_20930
DKO: I596_481
LRZ: BJI69_00885
LPY: FIV34_14505
LANH: KR767_20485
LFL: IM816_12160
LAEG: L2Y94_07345
LAEO: L2Y97_15665
LAES: L2Y96_15480
XBA: C7S18_00575
RBD: ALSL_0880
TAMN: N4264_19865
PPSE: BN5_3621(xylG)
PFUW: KF707C_15540(bzaD) KF707C_16090(salD)
PCQ: PcP3B5_23470(amnC)
PNT: G5B91_07420
PPW: PputW619_2012
PPI: ND088(nahI)
PPJ: RK21_04239
PVR: PverR02_14685
PKC: PKB_3261(amnc1) PKB_3609(amnc3)
PALK: PSAKL28_05930
PSOS: POS17_2264
PFK: PFAS1_28785
PSET: THL1_493
PALL: UYA_06710 UYA_06990 UYA_20165
PSEP: C4K39_5740
PPII: QL104_12030
PTRT: HU722_0014995
PTAE: NCTC10697_02312(amnC)
PHF: NLY38_02320
PPHN: HU825_04985
PSOA: PSm6_34070
PKJ: Q1W70_06535
PSC: A458_06530
PSTU: UIB01_22730
PBM: CL52_14700
AVN: Avin_08730(xylG) Avin_30620(lapC)
AVL: AvCA_08730(xylG) AvCA_30620(lapC)
AVD: AvCA6_08730(xylG) AvCA6_30620(lapC)
ACX: Achr_32710(xylG)
PAGR: E2H98_06030
HPEG: EAO82_00565 EAO82_09415
HAES: LO767_17660
PPHA: BVH74_06145
MAD: HP15_1111(betB) HP15_4032(betB)
MSR: AU15_09320 AU15_22425
MLQ: ASQ50_09225
MSQ: BKP64_13860
MARJ: MARI_05430(xylG)
MALL: PBN92_01660
MSHE: MAALD49_03400 MAALD49_03840
MANP: EHN06_02435
SWD: Swoo_1410
SEUR: FM038_016485
COZ: A3Q34_02635
COLW: A3Q33_02670
COV: EKO29_05100
CBER: B5D82_03525
THT: E2K93_11185
THAB: LP316_08945
TPSY: RGQ13_14555
TNN: RI845_05110
TFT: RI844_19335
THAT: H3N35_10260
TACT: SG35_010845
TVD: SG34_018580
LAL: AT746_01255
SALH: HMF8227_02739(dmpC)
AFUS: EYZ66_02610 EYZ66_02675
MMAI: sS8_3506
MSZE: MSZNOR_2869(dmpC)
CYQ: Q91_0507(xylG) Q91_1784(lapC)
CZA: CYCME_0670 CYCME_2104
CYY: CPC19_03895 CPC19_10520
BLEP: AL038_01305
THIS: HZT40_10600
WMA: WM2015_1463
WEZ: IC757_01595
TBN: TBH_C0927
HCS: FF32_08345
HBP: HPTD01_725
HAXH: J4377_02185
HALK: CUU95_03835
HVN: EI420_02095
APAC: S7S_06985
MGEO: CFI10_04950
MSEC: LN244_11335
NCU: F0U83_03040
NJP: NEJAP_0670
NIK: F5I99_10115 F5I99_10525
AJP: AMJAP_3000(dmpC)
PLEI: Q9312_09560
ASIM: FE240_03495
ZDF: AN401_14590
KKO: Kkor_0387
KGE: TQ33_1983
KSD: KS2013_2033
KPD: CW740_01675
KAM: SR900_00150
SINI: GT972_13720
GBI: PG2T_02235
NZO: SAMEA4504057_0449(aldA_1)
NCI: NCTC10296_00912(aldA_2)
NWD: H3L96_04750
NDU: LVJ88_00605
VFF: VITFI_CDS1391
VMS: LVJ82_11865
PTES: JQU52_04875
USU: LVJ78_03675
CHRO: CXB49_03835
CRZ: D1345_11535
CHAE: CH06BL_23640
AQS: DKK66_07230
AQL: BXU06_16865
RSO: RSp0890(dmpC)
RSE: F504_4327
RPU: CDC45_22065
RNC: GO999_18480
RSM: CMR15_mp10874
RPI: Rpic_4622
RPF: Rpic12D_3546
RPJ: N234_08145(gabD) N234_12220
RIN: ACS15_4686
REH: H16_B0547(h16_B0547)
CNC: CNE_2c04930(dmpC) CNE_BB1p12000(dmpC1) CNE_BB1p13290(dmpC2)
REU: Reut_B5498 Reut_B5689
RME: Rmet_1322(dmpC) Rmet_5206(amnC)
CBW: RR42_m1056 RR42_s2485
CCUP: BKK81_23305 BKK81_27085
CUP: BKK80_29235 BKK80_33010
CUU: BKK79_23895 BKK79_35185
COX: E0W60_03770 E0W60_07770
CCAX: KZ686_09990
CUK: KB879_20185
CNAN: A2G96_09310 A2G96_22765
BVI: Bcep1808_7602
BUR: Bcep18194_B2962 Bcep18194_C7647
BCJ: BCAM2132(nbaE)
BCEN: DM39_4835
BCEO: I35_6014(nbaE)
BMUL: NP80_3862
BCT: GEM_5404
BCED: DM42_4994
BCON: NL30_24605
BDF: WI26_15980
BTEI: WS51_00555
BPSL: WS57_12170
BSTL: BBJ41_10505 BBJ41_33975
BANN: JFN94_19120
BARI: NLX30_35130
BAEN: L3V59_30390
BUG: BC1001_3834
BUQ: AC233_11200
BXE: Bxe_A1147(amnC)
BXB: DR64_3306
BPX: BUPH_00408
BPY: Bphyt_1465
BFN: OI25_258
PARB: CJU94_37865 CJU94_38110
PTER: C2L65_38870
PBRY: NDK50_06165
PPAI: E1956_27295
PHUN: U0042_01165 U0042_26765
BRH: RBRH_03003
PPK: U875_01905 U875_06935 U875_20575
PPNO: DA70_13265 DA70_24010
PPNM: LV28_06695 LV28_17435
PRB: X636_02635 X636_07565 X636_13600
PPUL: RO07_00735 RO07_11540
PSPU: NA29_07455 NA29_10890
PAPI: SG18_00950 SG18_11865
PVE: UC34_03315 UC34_17030
POX: MB84_07750 MB84_21810
PFG: AB870_04075 AB870_14465
PNR: AT302_11495 AT302_15075
PAND: DRB87_15740
PFIB: PI93_002965 PI93_010955
PCOM: NTU39_03670 NTU39_18740
PANN: PanNE5_28130
PANX: OYT13_16975
LIMN: HKT17_03810
BAV: BAV0552(amnC)
BHZ: ACR54_00824(amnC_1)
BOJ: CBF45_01495 CBF45_04520 CBF45_17005
AXY: AXYL_02527 AXYL_05539
AXO: NH44784_030391
AXN: AX27061_5279
AXX: ERS451415_05308(amnC)
ADT: APT56_24280
AIS: BUW96_02880 BUW96_16325
ASW: CVS48_11355
ACHR: C2U31_27050
ACHB: DVB37_23455
ADY: HLG70_11220 HLG70_26345
APES: FOC84_00330 FOC84_18205 FOC84_33095
AAEG: RA224_05025 RA224_20180
ASEL: RAS12_26790
PUT: PT7_3613
PUD: G9Q38_13475
CDN: BN940_01146 BN940_04321
PIG: EGT29_02070 EGT29_19220 EGT29_19355
KGY: EHF36_01680 EHF36_16945
PARK: LSG25_19445
RLH: MIZ03_0645 MIZ03_1020
POL: Bpro_5132
AJS: Ajs_0220
ACID: CBP33_01090
ACIP: CBP36_01190
ACIN: CBP34_01100
ACIS: CBP35_17760
ACIV: EXV95_22330
AAA: Acav_3012
VEI: Veis_2787
VPD: VAPA_1c22810
VBO: CKY39_28515
VAV: IG196_08120
CTT: CtCNB1_3151
COF: FOZ74_08295
ADN: Alide_0335
ADK: Alide2_0280
OTD: J1M35_00060
HYL: LPB072_18170
HPSE: HPF_01880(xylG1)
HYN: F9K07_02745
HTN: KI616_01975
DIH: G7047_01680 G7047_06960
DRG: H9K76_11635 H9K76_22935
SIMP: C6571_13610
MELA: C6568_07865
MJE: LVC68_00995
STHM: IS481_10520
SAQA: OMP39_09100
MPT: Mpe_A2275 Mpe_A3326
METP: C1M51_06465 C1M51_15410
SNN: EWH46_19330
SMIO: CATMQ487_04120 CATMQ487_17550
IDC: LRM40_19560
LCH: Lcho_3354
JAG: GJA_237
HEE: hmeg3_19545
TMJ: P0M04_30680
RBU: PG1C_09710
DAR: Daro_2775 Daro_3787 Daro_3806
DEY: HYN24_14135 HYN24_14225
DDEN: KI615_16895
FLE: KI610_08570 KI610_13415 KI610_15475
AZO: azo1852(lapC) azo2435(nahI)
AOA: dqs_2005 dqs_2579
AZD: CDA09_10315 CDA09_10435
AZR: CJ010_12245 CJ010_15225
TMZ: Tmz1t_3092
THU: AC731_001805
THAU: C4PIVTH_2806(dmpC)
THK: CCZ27_10700 CCZ27_10775 CCZ27_16270
THAG: CKCBHOJB_03303(xylG)
AZQ: G3580_00530 G3580_08260
NRH: T8J41_00460
PLA: Plav_1786
ARA: Arad_7263(betB)
BSEP: HAP48_0048685
BOI: BLM15_28155
XDI: EZH22_00770
MSL: Msil_1476
MTUN: MTUNDRAET4_3895(dmpC)
CHEL: AL346_10040
MAAD: AZF01_08290
MLUT: JET14_11050
PSTG: E8M01_24785
BBUL: U0030_00105
JAN: Jann_3775
OCT: FTO60_10575
CEH: CEW89_11430
OCD: FHY55_16240
PALS: PAF20_14415
TEC: AKL02_008250
CACT: HZ995_11525
THAS: C6Y53_10940
GAK: X907_0751
NAR: Saro_3855
NPP: PP1Y_AT15685 PP1Y_AT31595
NPN: JI59_24625
NOT: C7W88_16330
NOG: GKE62_05100
NHUM: PQ457_19230
SMAG: AN936_00735
SMAZ: LH19_00745
STER: AOA14_03900
SGI: SGRAN_3552(amnC)
SPHO: C3E99_12575
SPEG: SPYCW_2519(xylGI)
SWI: Swit_3519
SPHD: HY78_06685
SPKC: KC8_11570
SJP: SJA_C1-11860(hpaE_xylG)
SINB: SIDU_08335
SYB: TZ53_09005 TZ53_23450
SHYD: CJD35_06485
SUFL: FIL70_19010
SBAR: H5V43_20660 H5V43_22325
SPPH: KFK14_16495
SPAG: sphantq_04468(xylG)
SPHY: CHN51_06960
SLAA: EUU25_08790
SPHJ: BSL82_10460
CNA: AB433_18135
ERY: CP97_14215
KSC: CD178_01493(amnC)
NCB: C0V82_23395
HTQ: FRZ44_17510(hpcC)
HADH: FRZ61_29630
MAGQ: MGMAQ_0648
TMO: TMO_b0431(dmpC)
PAQI: KW060_12525
GSO: PH603_02970 PH603_12410
HTL: HPTL_0058
ACIB: ACBT_0262(dmpC)
AFC: AFAEC_1847(dmpC)
AAQI: AAQM_0979(dmpC)
ACLO: ACLO_a0142(dmpC)
ADZ: ADFLV_2554(dmpC)
ARC: ABLL_2445
AROS: NJU99_01635
ALK: ALEK_0380(dmpC)
AANA: AANAER_1257(dmpC)
MXA: MXAN_0921
MSD: MYSTI_00939
MYM: A176_006058
MFB: MFUL124B02_05280
MYX: QEG98_05305
MLAN: JY572_21850
CCX: COCOR_00871(amnC)
MFU: LILAB_04105
MMAS: MYMAC_000943
PPAK: JY651_34550
SUR: STAUR_2723
AGE: AA314_01332
AVM: JQX13_18945
MBD: MEBOL_007655
PCAY: FRD00_12790
BBAE: FRD01_09595
BBAT: Bdt_0556
BBAC: EP01_17230
BDQ: CIK05_11245
BDC: DOE51_02900
BDZ: DOM22_02555
BLI: BL03906
BLD: BLi03994(dmpC)
BLH: BaLi_c40080
BSON: S101395_00391(dmpC)
BCA: BCE_2154
BCX: BCA_2152
BCF: bcf_10200
BCER: BCK_24235
BCEF: BcrFT9_01687
BTL: BALH_1841
BMYC: DJ92_4635
BTRO: FJR70_09235
BNT: GSN03_10135
BSM: BSM4216_0945
BGY: BGLY_4398
BFD: NCTC4823_00790(aldA)
BACI: B1NLA3E_08450 B1NLA3E_09290
GST: HW35_13035
BACO: OXB_2507
BACQ: DOE78_09215
BAQU: K6959_02320
BHK: B4U37_13950
BMQ: BMQ_3590
BMD: BMD_3575
BMEG: BG04_464
BPF: BpOF4_12595
OCN: CUC15_03665
OCB: CV093_03765
GTN: GTNG_3154(nbaE)
GYC: GYMC61_2295
GYA: GYMC52_1423
GCT: GC56T3_2058
GMC: GY4MC1_1599
GGH: GHH_c14810(dmpC)
GJF: M493_17930
GZA: IC807_03350
GTH: Geoth_1682
PTL: AOT13_14425
PCAL: BV455_00224(xylG)
PARG: PspKH34_14890 PspKH34_15510
ASED: IRT44_17635
LGY: T479_19630
LYB: C3943_22660
LYZ: DCE79_01740
LPAK: GDS87_20215
LYC: FH508_0003685
VIG: BKP57_09395
VNT: OLD84_14535 OLD84_14660
VIK: KFZ58_14515
LAO: AOX59_17235
FPN: ABE65_004725
FAR: ABE41_004870
APAK: AP3564_06575
ACOP: RI196_01670
BSJ: UP17_10510
PASA: BAOM_0496(dmpC)
PFRI: L8956_11375
RUE: DT065_12705 DT065_13775 DT065_15100 DT065_15220
SALE: EPH95_15025
NTM: BTDUT50_14565
NDT: L1999_11890 L1999_17425 L1999_17850
NCM: QNK12_05485
NNV: QNH39_24875
AIA: AWH56_018035
ROSS: V2W31_07730
BOU: I5818_04785
GAJ: MY490_08555
MSUT: LC048_10430
HYI: K2M58_09720
BBE: BBR47_29750(dhaS)
BFM: BP422_09705
BPAB: PSE45_08135
BHUI: LOK74_00595
BAYD: BSPP4475_07450(hpaE)
BBOR: RFB14_22170
BREH: HP435_08270
PNP: IJ22_00660
ANX: ACH33_11720
ASOC: CB4_02007(amnC_1) CB4_02455(xylG)
ATHE: K3F53_07220
AUD: PO771_09020
ANEU: PP175_12675
COH: EAV92_02590
AAC: Aaci_1622
AAD: TC41_1518(hpaE)
AACO: K1I37_06145
ADAU: NZD86_06120
AFAS: NZD89_10095
ALIC: GI364_17555
BTS: Btus_0966
KYR: CVV65_10360 CVV65_11305
EFF: skT53_33740
FFE: LSG31_21100
SOB: CSE16_14645
PLIQ: QWY22_04090
PSHE: QWY16_07640
SPAE: E2C16_04445 E2C16_12265
SPOO: J3U78_11190
SURL: BI350_00140
TMR: Tmar_1783
SAY: TPY_0646(hpaE)
SAP: Sulac_2993
LPIL: LIP_2170
MIT: OCO_14810
MIA: OCU_15250
MMAN: MMAN_42260
MJL: Mjls_4206
MHEV: MHEL_01580
MMON: EWR22_21580
MGO: AFA91_00050
MAUS: JN090_26265
CEE: CENDO_03495(amnC)
NFA: NFA_30520
NFR: ERS450000_01013(xylG)
NNO: NONO_c62070
NTP: CRH09_30210
RHA: RHA1_ro03868
RER: RER_04700 RER_59330 RER_59420
REY: O5Y_02260
REB: XU06_02460
RQI: C1M55_02645
ROP: ROP_37370 ROP_54040
RPY: Y013_12510
RBY: CEJ39_23380
RAV: AAT18_08160
RRZ: CS378_23180
RHQ: IM25_04135
RHOD: AOT96_13010
RRT: 4535765_01258(amnC_1) 4535765_01264(amnC_2)
RKO: JWS14_41345
RGO: KYT97_21975
ROZ: CBI38_22810
RPSK: JWS13_12615 JWS13_19015
RHOO: RA302_02490
RHOU: KZJ41_08725
RHOW: A4U64_16420
RHOJ: JVH1_17180
REQ: REQ_05040(amnC)
GBR: Gbro_0237
GTA: BCM27_21885
GOC: CXX93_11290
GOS: QAD21_20925
GOJ: GR168_19985
GOI: LK459_10080
GHN: MVF96_20940
GSI: P5P27_10840
DIZ: CT688_01910
TOY: FO059_00300
SANL: KZO11_33910
SGRF: SGFS_101490
SCB: SCAB_15221(amnC) SCAB_9701(hpaE)
SSX: SACTE_4117
SRC: M271_42595
SBH: SBI_01538
STRT: A8713_24460
SCLF: BB341_04925
SGS: AVL59_13460
STSI: A4E84_37260
SLS: SLINC_8207
SVU: B1H20_29100
SGE: DWG14_00345(xylG_1) DWG14_08254(amnC)
SLK: SLUN_38545
SCYA: EJ357_37720
SNK: CP967_06825
SAQU: EJC51_43200
SSUB: CP968_28075
SCHA: CP983_05180
SFEU: IM697_27560
SCAL: I6J39_28950
SROI: IAG44_01300 IAG44_38980
STRY: EQG64_09015
SGOB: test1122_23010
SINE: KI385_15820
SLF: JEQ17_41615
SDEC: L3078_40750
SDUR: M4V62_28355
SAKB: K1J60_02955
SCAE: IHE65_03930
SLON: LGI35_40735
SDRZ: NEH16_30295
STUD: STRTU_001644
SANT: QR300_10280
SKG: KJK29_00600
SCOA: QU709_02950
STRZ: OYE22_00310
SPRF: K4G22_29885
SLUO: PS467_00415
SCAJ: O1G22_42220
KIT: CFP65_1239
YIA: LO772_34525
MAUG: KV397_17155
MSUF: KV394_04945
RPLA: A4Z71_05995
MVD: AWU67_16670
AGY: ATC03_02600
AMAU: DSM26151_04210(amnC_1)
ASOI: MTP13_01900
AMIN: AUMI_10070
AUM: AURMO_01499
AUW: AURUGA1_01411(betB_2)
AUT: AINA4_13530
MDB: OVN18_08705
SALA: ESZ53_13890
LTR: EVS81_03275
GLN: F1C58_04490
ACIT: HPK19_02415
ARZ: AUT26_08855
DNI: HX89_01500
DAY: FV141_00665
DERM: H7F30_02220
XYL: ET495_01770
ICA: Intca_1091
JTE: ASJ30_00120
JLI: EXU32_15345
JME: EEW87_015430
JAY: H7A72_00120
JCR: O9K63_12605
PHW: G7075_13150
PEI: H9L10_13730
ORD: L0A91_02215
OCP: NF557_14850 NF557_15610
AUS: IPK37_11700
RAIN: Rai3103_12630
NARO: CFH99_04920
KFL: Kfla_5493
KQI: F1D05_11675
KSL: OG809_02130
KRI: OX958_09375
TCU: Tcur_0539
ACTW: F7P10_40020
AGRA: AGRA3207_000781 AGRA3207_001815
AMAZ: LUW76_05285 LUW76_20655 LUW76_22715 LUW76_47875
ACIR: OG979_20835 OG979_41965
SPIQ: OHA34_00535
SRO: Sros_7502 Sros_9116
NOA: BKM31_47335
NOW: GBF35_49965
NCX: Nocox_25070(amnC1) Nocox_40770(amnC2)
NGN: LCN96_27995 LCN96_28035 LCN96_54785
NFS: OIE67_45805
MHAI: OHB01_10110 OHB01_32110
FRI: FraEuI1c_1246
ACE: Acel_1100
AMYC: CU254_17660
AACD: LWP59_38190
AROO: NQK81_00845
ARHD: VSH64_19070 VSH64_30325 VSH64_35360
ACOR: LCL61_24540
PDX: Psed_2510
PBRO: HOP40_31850
PPEL: H6H00_29930
KAL: KALB_2083
KUT: JJ691_12070 JJ691_23980 JJ691_37130 JJ691_54090
KPHY: AOZ06_35745
ALO: CRK56596
CROS: N8J89_10330
STP: Strop_3528
SAQ: Sare_3903
MAU: Micau_4941
MIL: ML5_3354
MICB: MicB006_3973
MTUA: CSH63_33385
MTEM: GCE86_19400
MCAB: HXZ27_25050
MSAG: GCM10017556_52240
VMA: VAB18032_17800 VAB18032_28761
MCRA: ID554_21660 ID554_30910
VER: HUT12_13575 HUT12_26070
MENO: Jiend_41000
MCHL: PVK74_15050
MFEU: H1D33_00400
MPRN: Q3V37_13140
MHAW: RMN56_17985
MICF: QQG74_13345 QQG74_25605
ASIC: Q0Z83_068140
PLK: CIK06_22420
PFLA: Pflav_027560
PSUU: Psuf_068120 Psuf_082380 Psuf_082390
PRY: Prubr_10630 Prubr_59220
CATI: CS0771_01300
DFU: Dfulv_27735
DROS: Drose_21610
DACT: KZZ52_26430 KZZ52_45205
NHY: JQS43_06600
JCY: M6B22_15190
RMAR: GBA65_17330
LEPT: JVX88_10705
RRS: RoseRS_2577
RCA: Rcas_2406
CAU: Caur_1356
CHL: Chy400_1478
CAG: Cagg_2038
TTJ: TTHB240(TTHB240)
TTL: TtJL18_2422
TSC: TSC_c11600
THC: TCCBUS3UF1_13030
TOS: Theos_2470
TBC: A0O31_00089
TANT: KNN15_10830
VAB: WPS_24990
MFF: MFFC18_36440(amnC_2)
GES: VT84_03880(amnC)
GMS: SOIL9_79350
UAM: UABAM_05929
ABA: Acid345_0685
CTM: Cabther_A0029
CVL: J8C06_00145
CHLO: J8C02_00140
SCOR: J3U87_19665
PGO: FSB84_28995
AUP: AsAng_0030260
FLI: Fleli_4022
HSW: Hsw_0099
HYM: N008_07450
HYD: PK28_02600
HYE: AM218_13535
HYG: AUC43_04980
HYH: D3Y59_14235
HYJ: FHG12_07405
HRS: HER32_09595
HBN: GUY19_14855
HTS: HMJ29_08265
HMT: MTP16_05670
HTB: MTX78_21565
HYK: O9Z63_18075
HSK: H4317_18575
HCW: O3303_15975
HSB: MWH26_18750
HCU: MUN79_06070
HCF: MUN80_05830
PKO: PKOR_07060
PACT: CA264_17995
RUF: TH63_16330
RTI: DC20_06920
RUD: TH61_07810
NIB: GU926_13605
MTT: Ftrac_2830
MHAA: Q3Y49_07345
MARP: QYS47_34765
MSAA: QYS49_33940
CLIT: OQ292_12325
IRO: RT717_22255
CHRW: KA713_12395
CHK: D4L85_06690
FUV: JR347_00135
FMM: LVD15_09895
FUA: LVD17_06190
FLW: LVD16_06300
RCG: N7E81_01035
RSR: T7867_03130
CAT: CA2559_07430
KDI: Krodi_1916
DOK: MED134_12911
DDO: I597_1376(amnC)
DOD: DCS32_02250
LAN: Lacal_1456
LVN: BWR22_13175
LACI: CW733_09595
LNU: N7U66_09490
LACW: FG167_02330
ASL: Aeqsu_0473
AEV: EI546_00335
AIC: JK629_01360
AEQU: QCQ61_07850
PSYD: IMZ30_02230
NDO: DDD_2048
NOM: AAT17_09460
NSD: BST91_09375
NOB: CW736_01885
NUL: R1T42_09560
POM: MED152_12769
POB: LPB03_06875
PRN: BW723_00735
POLA: BXQ17_06205
POA: CW731_07310
PHAL: H9I45_07180
PLIT: K8354_01550
PPEC: H9W90_08155
PBAT: JL193_14270
PCEA: J3359_06220
PHG: KCTC32516_00165(amnC)
WIN: WPG_2044
WIJ: BWZ20_05975
TEN: LPB136_00565
TJE: TJEJU_1410(dmpC)
TMAR: MARIT_1046(dmpC)
TMP: F9Y86_12505
TOV: PG911_13795
TRT: PG912_04815
TPAC: PG913_03415
TTG: P8625_16015
TSIG: D6T69_12450
FOR: FORMB_05920
FOH: FORMA_06690
OLL: CW732_07060
OAQ: DZC78_13415
FEK: C1H87_06615
FAY: Q4Q34_02565
TAJ: C1A40_02560
AUE: C5O00_08945
KOS: KORDIASMS9_02221(amnC)
KAN: IMCC3317_39800(amnC)
MARF: CJ739_785
PSYN: E9099_03025
PPON: MUN68_001700
OCI: FEZ18_11750
MESQ: C7H62_1604
ALTI: ALE3EI_0273
MARX: INR76_01215
SABU: MBM09_05730
BIA: GMA17_09785
FBE: FF125_14715
ALUT: O5O44_13190
AEST: RBH94_09730
MANG: RBH95_14600
MCAA: R3L15_01910
HWS: RNZ46_10190
MGEL: G5B37_13135
FBQ: D1817_12575
FTE: Fluta_1400
FLU: CHH17_18090
CRM: K6119_14505
OHO: Oweho_2603
CHYD: H4K34_09055
PTAN: CRYO30217_00030(amnC)
BBAU: AEM51_05930
RLO: GQ464_001790
AG: AAA26053(xylG) BAH79100(praB)
 » show all
Reference
PMID:7868591 (EC:1.2.1.85)
  Authors
Inoue J, Shaw JP, Rekik M, Harayama S
  Title
Overlapping substrate specificities of benzaldehyde dehydrogenase (the xylC gene product) and 2-hydroxymuconic semialdehyde dehydrogenase (the xylG gene product) encoded by TOL plasmid pWW0 of Pseudomonas putida.
  Journal
J Bacteriol 177:1196-201 (1995)
DOI:10.1128/JB.177.5.1196-1201.1995
  Sequence
[ag:AAA26053]
Reference
PMID:19717587 (EC:1.2.1.85)
  Authors
Kasai D, Fujinami T, Abe T, Mase K, Katayama Y, Fukuda M, Masai E
  Title
Uncovering the protocatechuate 2,3-cleavage pathway genes.
  Journal
J Bacteriol 191:6758-68 (2009)
DOI:10.1128/JB.00840-09
  Sequence
[ag:BAH79100]
Reference
PMID:11081795 (EC:1.2.1.32)
  Authors
Takenaka S, Murakami S, Kim YJ, Aoki K
  Title
Complete nucleotide sequence and functional analysis of the genes for 2-aminophenol metabolism from Pseudomonas sp. AP-3.
  Journal
Arch Microbiol 174:265-72 (2000)
DOI:10.1007/s002030000203
LinkDB

KEGG   ENZYME: 1.2.1.85
Entry
EC 1.2.1.85                 Enzyme                                 
Name
2-hydroxymuconate-6-semialdehyde dehydrogenase;
xylG (gene name);
praB (gene name)
Class
Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With NAD+ or NADP+ as acceptor
Sysname
2-hydroxymuconate-6-semialdehyde:NAD+ oxidoreductase
Reaction(IUBMB)
2-hydroxymuconate-6-semialdehyde + NAD+ + H2O = (2Z,4E)-2-hydroxyhexa-2,4-dienedioate + NADH + 2 H+ [RN:R02762]
Reaction(KEGG)
R02762;
(other) R05353
Substrate
2-hydroxymuconate-6-semialdehyde [CPD:C00682];
NAD+ [CPD:C00003];
H2O [CPD:C00001]
Product
(2Z,4E)-2-hydroxyhexa-2,4-dienedioate;
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
This substrate for this enzyme is formed by meta ring cleavage of catechol (EC 1.13.11.2, catechol 2,3-dioxygenase), and is an intermediate in the bacterial degradation of several aromatic compounds. Has lower activity with benzaldehyde [1]. Activity with NAD+ is more than 10-fold higher than with NADP+ [3]. cf. EC 1.2.1.32, aminomuconate-semialdehyde dehydrogenase.
History
EC 1.2.1.85 created 2012
Pathway
ec00362  Benzoate degradation
ec00622  Xylene degradation
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K10217  aminomuconate-semialdehyde/2-hydroxymuconate-6-semialdehyde dehydrogenase
Genes
PGE: LG71_12245
SLQ: M495_05225
PROD: PCO85_03385
PSD: DSC_09155
PMEX: H4W19_03340
PJP: LAG73_06440
LAB: LA76x_2548(aldH8A1)
LAQ: GLA29479_1093
LCP: LC55x_2794(aldH8A1)
LGU: LG3211_2666(aldh8a1)
LEZ: GLE_2672
LEM: LEN_2363
LMB: C9I47_1501
LYT: DWG18_05815
LUE: DCD74_03960
LYJ: FKV23_07545
LSOL: GOY17_11460
LSX: H8B22_00640
LARE: HIV01_004055
LHX: LYSHEL_29980(hpaE)
LCAS: LYSCAS_29950(hpaE)
LCIC: INQ41_07790
LAVI: INQ42_07225
LLZ: LYB30171_01459(amnC)
LAUX: LA521A_22220
LYA: RDV84_19010
LSY: H8L67_00465
LSF: I8J32_011910
LUM: CNR27_08240
LUS: E5843_08240
LUG: FPZ22_13395
LFX: LU699_16000
LUJ: BGP89_12815
THES: FHQ07_01245
THEH: G7079_08025
TCN: H9L16_12765
TBV: H9L17_01795
THEX: ICG51_000383
XBC: ELE36_12500
FSG: LQ771_09720
FED: LQ772_10970
RHD: R2APBS1_1171
RGL: CS053_06000
RTH: LRK53_07370 LRK53_10265
DJI: CH75_03340
DJA: HY57_09330
DYE: EO087_08395
DCS: ISN74_04660
DTL: H8F01_15810
DTA: DYST_01720
DYG: DYGSA30_20930
DKO: I596_481
LRZ: BJI69_00885
LPY: FIV34_14505
LANH: KR767_20485
LFL: IM816_12160
LAEG: L2Y94_07345
LAEO: L2Y97_15665
LAES: L2Y96_15480
XBA: C7S18_00575
RBD: ALSL_0880
TAMN: N4264_19865
PPSE: BN5_3621(xylG)
PFUW: KF707C_15540(bzaD) KF707C_16090(salD)
PCQ: PcP3B5_23470(amnC)
PNT: G5B91_07420
PPW: PputW619_2012
PPI: ND088(nahI)
PPJ: RK21_04239
PVR: PverR02_14685
PKC: PKB_3261(amnc1) PKB_3609(amnc3)
PALK: PSAKL28_05930
PSOS: POS17_2264
PFK: PFAS1_28785
PSET: THL1_493
PALL: UYA_06710 UYA_06990 UYA_20165
PSEP: C4K39_5740
PPII: QL104_12030
PTRT: HU722_0014995
PTAE: NCTC10697_02312(amnC)
PHF: NLY38_02320
PPHN: HU825_04985
PSOA: PSm6_34070
PKJ: Q1W70_06535
PSC: A458_06530
PSTU: UIB01_22730
PBM: CL52_14700
AVN: Avin_08730(xylG) Avin_30620(lapC)
AVL: AvCA_08730(xylG) AvCA_30620(lapC)
AVD: AvCA6_08730(xylG) AvCA6_30620(lapC)
ACX: Achr_32710(xylG)
PAGR: E2H98_06030
HPEG: EAO82_00565 EAO82_09415
HAES: LO767_17660
PPHA: BVH74_06145
MAD: HP15_1111(betB) HP15_4032(betB)
MSR: AU15_09320 AU15_22425
MLQ: ASQ50_09225
MSQ: BKP64_13860
MARJ: MARI_05430(xylG)
MALL: PBN92_01660
MSHE: MAALD49_03400 MAALD49_03840
MANP: EHN06_02435
SWD: Swoo_1410
SEUR: FM038_016485
COZ: A3Q34_02635
COLW: A3Q33_02670
COV: EKO29_05100
CBER: B5D82_03525
THT: E2K93_11185
THAB: LP316_08945
TPSY: RGQ13_14555
TNN: RI845_05110
TFT: RI844_19335
THAT: H3N35_10260
TACT: SG35_010845
TVD: SG34_018580
LAL: AT746_01255
SALH: HMF8227_02739(dmpC)
AFUS: EYZ66_02610 EYZ66_02675
MMAI: sS8_3506
MSZE: MSZNOR_2869(dmpC)
CYQ: Q91_0507(xylG) Q91_1784(lapC)
CZA: CYCME_0670 CYCME_2104
CYY: CPC19_03895 CPC19_10520
BLEP: AL038_01305
THIS: HZT40_10600
WMA: WM2015_1463
WEZ: IC757_01595
TBN: TBH_C0927
HCS: FF32_08345
HBP: HPTD01_725
HAXH: J4377_02185
HALK: CUU95_03835
HVN: EI420_02095
APAC: S7S_06985
MGEO: CFI10_04950
MSEC: LN244_11335
NCU: F0U83_03040
NJP: NEJAP_0670
NIK: F5I99_10115 F5I99_10525
AJP: AMJAP_3000(dmpC)
PLEI: Q9312_09560
ASIM: FE240_03495
ZDF: AN401_14590
KKO: Kkor_0387
KGE: TQ33_1983
KSD: KS2013_2033
KPD: CW740_01675
KAM: SR900_00150
SINI: GT972_13720
GBI: PG2T_02235
NZO: SAMEA4504057_0449(aldA_1)
NCI: NCTC10296_00912(aldA_2)
NWD: H3L96_04750
NDU: LVJ88_00605
VFF: VITFI_CDS1391
VMS: LVJ82_11865
PTES: JQU52_04875
USU: LVJ78_03675
CHRO: CXB49_03835
CRZ: D1345_11535
CHAE: CH06BL_23640
AQS: DKK66_07230
AQL: BXU06_16865
RSO: RSp0890(dmpC)
RSE: F504_4327
RPU: CDC45_22065
RNC: GO999_18480
RSM: CMR15_mp10874
RPI: Rpic_4622
RPF: Rpic12D_3546
RPJ: N234_08145(gabD) N234_12220
RIN: ACS15_4686
REH: H16_B0547(h16_B0547)
CNC: CNE_2c04930(dmpC) CNE_BB1p12000(dmpC1) CNE_BB1p13290(dmpC2)
REU: Reut_B5498 Reut_B5689
RME: Rmet_1322(dmpC) Rmet_5206(amnC)
CBW: RR42_m1056 RR42_s2485
CCUP: BKK81_23305 BKK81_27085
CUP: BKK80_29235 BKK80_33010
CUU: BKK79_23895 BKK79_35185
COX: E0W60_03770 E0W60_07770
CCAX: KZ686_09990
CUK: KB879_20185
CNAN: A2G96_09310 A2G96_22765
BVI: Bcep1808_7602
BUR: Bcep18194_B2962 Bcep18194_C7647
BCJ: BCAM2132(nbaE)
BCEN: DM39_4835
BCEO: I35_6014(nbaE)
BMUL: NP80_3862
BCT: GEM_5404
BCED: DM42_4994
BCON: NL30_24605
BDF: WI26_15980
BTEI: WS51_00555
BPSL: WS57_12170
BSTL: BBJ41_10505 BBJ41_33975
BANN: JFN94_19120
BARI: NLX30_35130
BAEN: L3V59_30390
BUG: BC1001_3834
BUQ: AC233_11200
BXE: Bxe_A1147(amnC)
BXB: DR64_3306
BPX: BUPH_00408
BPY: Bphyt_1465
BFN: OI25_258
PARB: CJU94_37865 CJU94_38110
PTER: C2L65_38870
PBRY: NDK50_06165
PPAI: E1956_27295
PHUN: U0042_01165 U0042_26765
BRH: RBRH_03003
PPK: U875_01905 U875_06935 U875_20575
PPNO: DA70_13265 DA70_24010
PPNM: LV28_06695 LV28_17435
PRB: X636_02635 X636_07565 X636_13600
PPUL: RO07_00735 RO07_11540
PSPU: NA29_07455 NA29_10890
PAPI: SG18_00950 SG18_11865
PVE: UC34_03315 UC34_17030
POX: MB84_07750 MB84_21810
PFG: AB870_04075 AB870_14465
PNR: AT302_11495 AT302_15075
PAND: DRB87_15740
PFIB: PI93_002965 PI93_010955
PCOM: NTU39_03670 NTU39_18740
PANN: PanNE5_28130
PANX: OYT13_16975
LIMN: HKT17_03810
BAV: BAV0552(amnC)
BHZ: ACR54_00824(amnC_1)
BOJ: CBF45_01495 CBF45_04520 CBF45_17005
AXY: AXYL_02527 AXYL_05539
AXO: NH44784_030391
AXN: AX27061_5279
AXX: ERS451415_05308(amnC)
ADT: APT56_24280
AIS: BUW96_02880 BUW96_16325
ASW: CVS48_11355
ACHR: C2U31_27050
ACHB: DVB37_23455
ADY: HLG70_11220 HLG70_26345
APES: FOC84_00330 FOC84_18205 FOC84_33095
AAEG: RA224_05025 RA224_20180
ASEL: RAS12_26790
PUT: PT7_3613
PUD: G9Q38_13475
CDN: BN940_01146 BN940_04321
PIG: EGT29_02070 EGT29_19220 EGT29_19355
KGY: EHF36_01680 EHF36_16945
PARK: LSG25_19445
RLH: MIZ03_0645 MIZ03_1020
POL: Bpro_5132
AJS: Ajs_0220
ACID: CBP33_01090
ACIP: CBP36_01190
ACIN: CBP34_01100
ACIS: CBP35_17760
ACIV: EXV95_22330
AAA: Acav_3012
VEI: Veis_2787
VPD: VAPA_1c22810
VBO: CKY39_28515
VAV: IG196_08120
CTT: CtCNB1_3151
COF: FOZ74_08295
ADN: Alide_0335
ADK: Alide2_0280
OTD: J1M35_00060
HYL: LPB072_18170
HPSE: HPF_01880(xylG1)
HYN: F9K07_02745
HTN: KI616_01975
DIH: G7047_01680 G7047_06960
DRG: H9K76_11635 H9K76_22935
SIMP: C6571_13610
MELA: C6568_07865
MJE: LVC68_00995
STHM: IS481_10520
SAQA: OMP39_09100
MPT: Mpe_A2275 Mpe_A3326
METP: C1M51_06465 C1M51_15410
SNN: EWH46_19330
SMIO: CATMQ487_04120 CATMQ487_17550
IDC: LRM40_19560
LCH: Lcho_3354
JAG: GJA_237
HEE: hmeg3_19545
TMJ: P0M04_30680
RBU: PG1C_09710
DAR: Daro_2775 Daro_3787 Daro_3806
DEY: HYN24_14135 HYN24_14225
DDEN: KI615_16895
FLE: KI610_08570 KI610_13415 KI610_15475
AZO: azo1852(lapC) azo2435(nahI)
AOA: dqs_2005 dqs_2579
AZD: CDA09_10315 CDA09_10435
AZR: CJ010_12245 CJ010_15225
TMZ: Tmz1t_3092
THU: AC731_001805
THAU: C4PIVTH_2806(dmpC)
THK: CCZ27_10700 CCZ27_10775 CCZ27_16270
THAG: CKCBHOJB_03303(xylG)
AZQ: G3580_00530 G3580_08260
NRH: T8J41_00460
PLA: Plav_1786
ARA: Arad_7263(betB)
BSEP: HAP48_0048685
BOI: BLM15_28155
XDI: EZH22_00770
MSL: Msil_1476
MTUN: MTUNDRAET4_3895(dmpC)
CHEL: AL346_10040
MAAD: AZF01_08290
MLUT: JET14_11050
PSTG: E8M01_24785
BBUL: U0030_00105
JAN: Jann_3775
OCT: FTO60_10575
CEH: CEW89_11430
OCD: FHY55_16240
PALS: PAF20_14415
TEC: AKL02_008250
CACT: HZ995_11525
THAS: C6Y53_10940
GAK: X907_0751
NAR: Saro_3855
NPP: PP1Y_AT15685 PP1Y_AT31595
NPN: JI59_24625
NOT: C7W88_16330
NOG: GKE62_05100
NHUM: PQ457_19230
SMAG: AN936_00735
SMAZ: LH19_00745
STER: AOA14_03900
SGI: SGRAN_3552(amnC)
SPHO: C3E99_12575
SPEG: SPYCW_2519(xylGI)
SWI: Swit_3519
SPHD: HY78_06685
SPKC: KC8_11570
SJP: SJA_C1-11860(hpaE_xylG)
SINB: SIDU_08335
SYB: TZ53_09005 TZ53_23450
SHYD: CJD35_06485
SUFL: FIL70_19010
SBAR: H5V43_20660 H5V43_22325
SPPH: KFK14_16495
SPAG: sphantq_04468(xylG)
SPHY: CHN51_06960
SLAA: EUU25_08790
SPHJ: BSL82_10460
CNA: AB433_18135
ERY: CP97_14215
KSC: CD178_01493(amnC)
NCB: C0V82_23395
HTQ: FRZ44_17510(hpcC)
HADH: FRZ61_29630
MAGQ: MGMAQ_0648
TMO: TMO_b0431(dmpC)
PAQI: KW060_12525
GSO: PH603_02970 PH603_12410
HTL: HPTL_0058
ACIB: ACBT_0262(dmpC)
AFC: AFAEC_1847(dmpC)
AAQI: AAQM_0979(dmpC)
ACLO: ACLO_a0142(dmpC)
ADZ: ADFLV_2554(dmpC)
ARC: ABLL_2445
AROS: NJU99_01635
ALK: ALEK_0380(dmpC)
AANA: AANAER_1257(dmpC)
MXA: MXAN_0921
MSD: MYSTI_00939
MYM: A176_006058
MFB: MFUL124B02_05280
MYX: QEG98_05305
MLAN: JY572_21850
CCX: COCOR_00871(amnC)
MFU: LILAB_04105
MMAS: MYMAC_000943
PPAK: JY651_34550
SUR: STAUR_2723
AGE: AA314_01332
AVM: JQX13_18945
MBD: MEBOL_007655
PCAY: FRD00_12790
BBAE: FRD01_09595
BBAT: Bdt_0556
BBAC: EP01_17230
BDQ: CIK05_11245
BDC: DOE51_02900
BDZ: DOM22_02555
BLI: BL03906
BLD: BLi03994(dmpC)
BLH: BaLi_c40080
BSON: S101395_00391(dmpC)
BCA: BCE_2154
BCX: BCA_2152
BCF: bcf_10200
BCER: BCK_24235
BCEF: BcrFT9_01687
BTL: BALH_1841
BMYC: DJ92_4635
BTRO: FJR70_09235
BNT: GSN03_10135
BSM: BSM4216_0945
BGY: BGLY_4398
BFD: NCTC4823_00790(aldA)
BACI: B1NLA3E_08450 B1NLA3E_09290
GST: HW35_13035
BACO: OXB_2507
BACQ: DOE78_09215
BAQU: K6959_02320
BHK: B4U37_13950
BMQ: BMQ_3590
BMD: BMD_3575
BMEG: BG04_464
BPF: BpOF4_12595
OCN: CUC15_03665
OCB: CV093_03765
GTN: GTNG_3154(nbaE)
GYC: GYMC61_2295
GYA: GYMC52_1423
GCT: GC56T3_2058
GMC: GY4MC1_1599
GGH: GHH_c14810(dmpC)
GJF: M493_17930
GZA: IC807_03350
GTH: Geoth_1682
PTL: AOT13_14425
PCAL: BV455_00224(xylG)
PARG: PspKH34_14890 PspKH34_15510
ASED: IRT44_17635
LGY: T479_19630
LYB: C3943_22660
LYZ: DCE79_01740
LPAK: GDS87_20215
LYC: FH508_0003685
VIG: BKP57_09395
VNT: OLD84_14535 OLD84_14660
VIK: KFZ58_14515
LAO: AOX59_17235
FPN: ABE65_004725
FAR: ABE41_004870
APAK: AP3564_06575
ACOP: RI196_01670
BSJ: UP17_10510
PASA: BAOM_0496(dmpC)
PFRI: L8956_11375
RUE: DT065_12705 DT065_13775 DT065_15100 DT065_15220
SALE: EPH95_15025
NTM: BTDUT50_14565
NDT: L1999_11890 L1999_17425 L1999_17850
NCM: QNK12_05485
NNV: QNH39_24875
AIA: AWH56_018035
ROSS: V2W31_07730
BOU: I5818_04785
GAJ: MY490_08555
MSUT: LC048_10430
HYI: K2M58_09720
BBE: BBR47_29750(dhaS)
BFM: BP422_09705
BPAB: PSE45_08135
BHUI: LOK74_00595
BAYD: BSPP4475_07450(hpaE)
BBOR: RFB14_22170
BREH: HP435_08270
PNP: IJ22_00660
ANX: ACH33_11720
ASOC: CB4_02007(amnC_1) CB4_02455(xylG)
ATHE: K3F53_07220
AUD: PO771_09020
ANEU: PP175_12675
COH: EAV92_02590
AAC: Aaci_1622
AAD: TC41_1518(hpaE)
AACO: K1I37_06145
ADAU: NZD86_06120
AFAS: NZD89_10095
ALIC: GI364_17555
BTS: Btus_0966
KYR: CVV65_10360 CVV65_11305
EFF: skT53_33740
FFE: LSG31_21100
SOB: CSE16_14645
PLIQ: QWY22_04090
PSHE: QWY16_07640
SPAE: E2C16_04445 E2C16_12265
SPOO: J3U78_11190
SURL: BI350_00140
TMR: Tmar_1783
SAY: TPY_0646(hpaE)
SAP: Sulac_2993
LPIL: LIP_2170
MIT: OCO_14810
MIA: OCU_15250
MMAN: MMAN_42260
MJL: Mjls_4206
MHEV: MHEL_01580
MMON: EWR22_21580
MGO: AFA91_00050
MAUS: JN090_26265
CEE: CENDO_03495(amnC)
NFA: NFA_30520
NFR: ERS450000_01013(xylG)
NNO: NONO_c62070
NTP: CRH09_30210
RHA: RHA1_ro03868
RER: RER_04700 RER_59330 RER_59420
REY: O5Y_02260
REB: XU06_02460
RQI: C1M55_02645
ROP: ROP_37370 ROP_54040
RPY: Y013_12510
RBY: CEJ39_23380
RAV: AAT18_08160
RRZ: CS378_23180
RHQ: IM25_04135
RHOD: AOT96_13010
RRT: 4535765_01258(amnC_1) 4535765_01264(amnC_2)
RKO: JWS14_41345
RGO: KYT97_21975
ROZ: CBI38_22810
RPSK: JWS13_12615 JWS13_19015
RHOO: RA302_02490
RHOU: KZJ41_08725
RHOW: A4U64_16420
RHOJ: JVH1_17180
REQ: REQ_05040(amnC)
GBR: Gbro_0237
GTA: BCM27_21885
GOC: CXX93_11290
GOS: QAD21_20925
GOJ: GR168_19985
GOI: LK459_10080
GHN: MVF96_20940
GSI: P5P27_10840
DIZ: CT688_01910
TOY: FO059_00300
SANL: KZO11_33910
SGRF: SGFS_101490
SCB: SCAB_15221(amnC) SCAB_9701(hpaE)
SSX: SACTE_4117
SRC: M271_42595
SBH: SBI_01538
STRT: A8713_24460
SCLF: BB341_04925
SGS: AVL59_13460
STSI: A4E84_37260
SLS: SLINC_8207
SVU: B1H20_29100
SGE: DWG14_00345(xylG_1) DWG14_08254(amnC)
SLK: SLUN_38545
SCYA: EJ357_37720
SNK: CP967_06825
SAQU: EJC51_43200
SSUB: CP968_28075
SCHA: CP983_05180
SFEU: IM697_27560
SCAL: I6J39_28950
SROI: IAG44_01300 IAG44_38980
STRY: EQG64_09015
SGOB: test1122_23010
SINE: KI385_15820
SLF: JEQ17_41615
SDEC: L3078_40750
SDUR: M4V62_28355
SAKB: K1J60_02955
SCAE: IHE65_03930
SLON: LGI35_40735
SDRZ: NEH16_30295
STUD: STRTU_001644
SANT: QR300_10280
SKG: KJK29_00600
SCOA: QU709_02950
STRZ: OYE22_00310
SPRF: K4G22_29885
SLUO: PS467_00415
SCAJ: O1G22_42220
KIT: CFP65_1239
YIA: LO772_34525
MAUG: KV397_17155
MSUF: KV394_04945
RPLA: A4Z71_05995
MVD: AWU67_16670
AGY: ATC03_02600
AMAU: DSM26151_04210(amnC_1)
ASOI: MTP13_01900
AMIN: AUMI_10070
AUM: AURMO_01499
AUW: AURUGA1_01411(betB_2)
AUT: AINA4_13530
MDB: OVN18_08705
SALA: ESZ53_13890
LTR: EVS81_03275
GLN: F1C58_04490
ACIT: HPK19_02415
ARZ: AUT26_08855
DNI: HX89_01500
DAY: FV141_00665
DERM: H7F30_02220
XYL: ET495_01770
ICA: Intca_1091
JTE: ASJ30_00120
JLI: EXU32_15345
JME: EEW87_015430
JAY: H7A72_00120
JCR: O9K63_12605
PHW: G7075_13150
PEI: H9L10_13730
ORD: L0A91_02215
OCP: NF557_14850 NF557_15610
AUS: IPK37_11700
RAIN: Rai3103_12630
NARO: CFH99_04920
KFL: Kfla_5493
KQI: F1D05_11675
KSL: OG809_02130
KRI: OX958_09375
TCU: Tcur_0539
ACTW: F7P10_40020
AGRA: AGRA3207_000781 AGRA3207_001815
AMAZ: LUW76_05285 LUW76_20655 LUW76_22715 LUW76_47875
ACIR: OG979_20835 OG979_41965
SPIQ: OHA34_00535
SRO: Sros_7502 Sros_9116
NOA: BKM31_47335
NOW: GBF35_49965
NCX: Nocox_25070(amnC1) Nocox_40770(amnC2)
NGN: LCN96_27995 LCN96_28035 LCN96_54785
NFS: OIE67_45805
MHAI: OHB01_10110 OHB01_32110
FRI: FraEuI1c_1246
ACE: Acel_1100
AMYC: CU254_17660
AACD: LWP59_38190
AROO: NQK81_00845
ARHD: VSH64_19070 VSH64_30325 VSH64_35360
ACOR: LCL61_24540
PDX: Psed_2510
PBRO: HOP40_31850
PPEL: H6H00_29930
KAL: KALB_2083
KUT: JJ691_12070 JJ691_23980 JJ691_37130 JJ691_54090
KPHY: AOZ06_35745
ALO: CRK56596
CROS: N8J89_10330
STP: Strop_3528
SAQ: Sare_3903
MAU: Micau_4941
MIL: ML5_3354
MICB: MicB006_3973
MTUA: CSH63_33385
MTEM: GCE86_19400
MCAB: HXZ27_25050
MSAG: GCM10017556_52240
VMA: VAB18032_17800 VAB18032_28761
MCRA: ID554_21660 ID554_30910
VER: HUT12_13575 HUT12_26070
MENO: Jiend_41000
MCHL: PVK74_15050
MFEU: H1D33_00400
MPRN: Q3V37_13140
MHAW: RMN56_17985
MICF: QQG74_13345 QQG74_25605
ASIC: Q0Z83_068140
PLK: CIK06_22420
PFLA: Pflav_027560
PSUU: Psuf_068120 Psuf_082380 Psuf_082390
PRY: Prubr_10630 Prubr_59220
CATI: CS0771_01300
DFU: Dfulv_27735
DROS: Drose_21610
DACT: KZZ52_26430 KZZ52_45205
NHY: JQS43_06600
JCY: M6B22_15190
RMAR: GBA65_17330
LEPT: JVX88_10705
RRS: RoseRS_2577
RCA: Rcas_2406
CAU: Caur_1356
CHL: Chy400_1478
CAG: Cagg_2038
TTJ: TTHB240(TTHB240)
TTL: TtJL18_2422
TSC: TSC_c11600
THC: TCCBUS3UF1_13030
TOS: Theos_2470
TBC: A0O31_00089
TANT: KNN15_10830
VAB: WPS_24990
MFF: MFFC18_36440(amnC_2)
GES: VT84_03880(amnC)
GMS: SOIL9_79350
UAM: UABAM_05929
ABA: Acid345_0685
CTM: Cabther_A0029
CVL: J8C06_00145
CHLO: J8C02_00140
SCOR: J3U87_19665
PGO: FSB84_28995
AUP: AsAng_0030260
FLI: Fleli_4022
HSW: Hsw_0099
HYM: N008_07450
HYD: PK28_02600
HYE: AM218_13535
HYG: AUC43_04980
HYH: D3Y59_14235
HYJ: FHG12_07405
HRS: HER32_09595
HBN: GUY19_14855
HTS: HMJ29_08265
HMT: MTP16_05670
HTB: MTX78_21565
HYK: O9Z63_18075
HSK: H4317_18575
HCW: O3303_15975
HSB: MWH26_18750
HCU: MUN79_06070
HCF: MUN80_05830
PKO: PKOR_07060
PACT: CA264_17995
RUF: TH63_16330
RTI: DC20_06920
RUD: TH61_07810
NIB: GU926_13605
MTT: Ftrac_2830
MHAA: Q3Y49_07345
MARP: QYS47_34765
MSAA: QYS49_33940
CLIT: OQ292_12325
IRO: RT717_22255
CHRW: KA713_12395
CHK: D4L85_06690
FUV: JR347_00135
FMM: LVD15_09895
FUA: LVD17_06190
FLW: LVD16_06300
RCG: N7E81_01035
RSR: T7867_03130
CAT: CA2559_07430
KDI: Krodi_1916
DOK: MED134_12911
DDO: I597_1376(amnC)
DOD: DCS32_02250
LAN: Lacal_1456
LVN: BWR22_13175
LACI: CW733_09595
LNU: N7U66_09490
LACW: FG167_02330
ASL: Aeqsu_0473
AEV: EI546_00335
AIC: JK629_01360
AEQU: QCQ61_07850
PSYD: IMZ30_02230
NDO: DDD_2048
NOM: AAT17_09460
NSD: BST91_09375
NOB: CW736_01885
NUL: R1T42_09560
POM: MED152_12769
POB: LPB03_06875
PRN: BW723_00735
POLA: BXQ17_06205
POA: CW731_07310
PHAL: H9I45_07180
PLIT: K8354_01550
PPEC: H9W90_08155
PBAT: JL193_14270
PCEA: J3359_06220
PHG: KCTC32516_00165(amnC)
WIN: WPG_2044
WIJ: BWZ20_05975
TEN: LPB136_00565
TJE: TJEJU_1410(dmpC)
TMAR: MARIT_1046(dmpC)
TMP: F9Y86_12505
TOV: PG911_13795
TRT: PG912_04815
TPAC: PG913_03415
TTG: P8625_16015
TSIG: D6T69_12450
FOR: FORMB_05920
FOH: FORMA_06690
OLL: CW732_07060
OAQ: DZC78_13415
FEK: C1H87_06615
FAY: Q4Q34_02565
TAJ: C1A40_02560
AUE: C5O00_08945
KOS: KORDIASMS9_02221(amnC)
KAN: IMCC3317_39800(amnC)
MARF: CJ739_785
PSYN: E9099_03025
PPON: MUN68_001700
OCI: FEZ18_11750
MESQ: C7H62_1604
ALTI: ALE3EI_0273
MARX: INR76_01215
SABU: MBM09_05730
BIA: GMA17_09785
FBE: FF125_14715
ALUT: O5O44_13190
AEST: RBH94_09730
MANG: RBH95_14600
MCAA: R3L15_01910
HWS: RNZ46_10190
MGEL: G5B37_13135
FBQ: D1817_12575
FTE: Fluta_1400
FLU: CHH17_18090
CRM: K6119_14505
OHO: Oweho_2603
CHYD: H4K34_09055
PTAN: CRYO30217_00030(amnC)
BBAU: AEM51_05930
RLO: GQ464_001790
 » show all
Reference
1  [PMID:7868591]
  Authors
Inoue J, Shaw JP, Rekik M, Harayama S
  Title
Overlapping substrate specificities of benzaldehyde dehydrogenase (the xylC gene product) and 2-hydroxymuconic semialdehyde dehydrogenase (the xylG gene product) encoded by TOL plasmid pWW0 of Pseudomonas putida.
  Journal
J Bacteriol 177:1196-201 (1995)
DOI:10.1128/JB.177.5.1196-1201.1995
  Sequence
[ag:AAA26053]
Reference
2  [PMID:17090920]
  Authors
Orii C, Takenaka S, Murakami S, Aoki K
  Title
Metabolism of 4-amino-3-hydroxybenzoic acid by Bordetella sp. strain 10d: A different modified meta-cleavage pathway for 2-aminophenols.
  Journal
Biosci Biotechnol Biochem 70:2653-61 (2006)
DOI:10.1271/bbb.60264
Reference
3  [PMID:19717587]
  Authors
Kasai D, Fujinami T, Abe T, Mase K, Katayama Y, Fukuda M, Masai E
  Title
Uncovering the protocatechuate 2,3-cleavage pathway genes.
  Journal
J Bacteriol 191:6758-68 (2009)
DOI:10.1128/JB.00840-09
  Sequence
[ag:BAH79100]
Other DBs
ExplorEnz - The Enzyme Database: 1.2.1.85
IUBMB Enzyme Nomenclature: 1.2.1.85
ExPASy - ENZYME nomenclature database: 1.2.1.85
BRENDA, the Enzyme Database: 1.2.1.85
LinkDB

KEGG   REACTION: R05353
Entry
R05353                      Reaction                               
Name
2-hydroxy-5-methyl-cis,cis-muconic semialdehyde:NAD+ 6-oxidoreductase
Definition
2-Hydroxy-5-methyl-cis,cis-muconic semialdehyde + NAD+ + H2O <=> 2-Hydroxy-5-methyl-cis,cis-muconate + NADH + H+
Equation
C06760 + C00003 + C00001 <=> C07478 + C00004 + C00080
Reaction class
RC00001  C00003_C00004
RC00254  C06760_C07478
Enzyme
1.2.1.85
Pathway
rn00622  Xylene degradation
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
rn01220  Degradation of aromatic compounds
Module
M00569  Catechol meta-cleavage, catechol => acetyl-CoA / 4-methylcatechol => propanoyl-CoA
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.1  With NAD+ or NADP+ as acceptor
    1.2.1.85
     R05353  2-Hydroxy-5-methyl-cis,cis-muconic semialdehyde + NAD+ + H2O <=> 2-Hydroxy-5-methyl-cis,cis-muconate + NADH + H+
Orthology
K10217  aminomuconate-semialdehyde/2-hydroxymuconate-6-semialdehyde dehydrogenase [EC:1.2.1.32 1.2.1.85]
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