KEGG ORTHOLOGY: K10618

ORTHOLOGY: K10618

Entry

K10618                      KO

Symbol

cymC

Name

p-cumic aldehyde dehydrogenase

Pathway

map00622

Xylene degradation

map01100

Metabolic pathways

map01120

Microbial metabolism in diverse environments

map01220

Degradation of aromatic compounds

Module

M00419

Cymene degradation, p-cymene => p-cumate

Reaction

R05235

p-cumic aldehyde:NAD+ oxidoreductase

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00622 Xylene degradation
    K10618  cymC; p-cumic aldehyde dehydrogenase

Genes

PPF:

PPX:

PMON:

PMOT:

PASI:

SNAN:

STAW:

BAEN:

BXE:

BXB:

THAU:

C4PIVTH_4359(dhaS)

NHUM:

PQ457_17045

SBIN:

SBA_ch1_21370(dhaS)

SPPH:

KFK14_17045

SPAG:

sphantq_03250(styD_1)

MMAN:

MMAN_13070

MSER:

MTY59_10310 MTY59_41760

MSIM:

MSIM_50150

MLW:	MJO58_14590

MBRD:

MBRA_56050

MPAA:

MKK62_10275

MKY:	IWGMT90018_17030

MWU:	PT015_07275

RKO:	JWS14_44130

RHOP:

D8W71_26670

RHOU:

KZJ41_26265

RHOW:

A4U64_26370

GJI:	H1R19_19285

SPIN:

KV203_07940

BLAP:

MVA48_23245

» show all

Reference

PMID:9150211

Authors

Eaton RW.

Title

p-Cymene catabolic pathway in Pseudomonas putida F1: cloning and characterization of DNA encoding conversion of p-cymene to p-cumate.

Journal

J Bacteriol 179:3171-80 (1997)
DOI:10.1128/JB.179.10.3171-3180.1997

Sequence

[ppf:Pput_2904]

LinkDB

REACTION: R05235

Entry

R05235                      Reaction

Name

p-cumic aldehyde:NAD+ oxidoreductase

Definition

4-Isopropylbenzaldehyde + NAD+ + H2O <=> p-Cumate + NADH + H+

Equation

C06577 + C00003 + C00001 <=> C06578 + C00004 + C00080

Reaction class

RC00001

C00003_C00004

RC00075

C06577_C06578

Enzyme

1.2.1.29

Pathway

rn00622

Xylene degradation

rn01100

Metabolic pathways

rn01120

Microbial metabolism in diverse environments

rn01220

Degradation of aromatic compounds

Module

M00419

Cymene degradation, p-cymene => p-cumate

Brite

Enzymatic reactions [BR:br08201]
1. Oxidoreductase reactions
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.1  With NAD+ or NADP+ as acceptor
    1.2.1.29
     R05235  4-Isopropylbenzaldehyde + NAD+ + H2O <=> p-Cumate + NADH + H+
IUBMB reaction hierarchy [BR:br08202]
1. Oxidoreductase reactions
  1.2.1.29
   R01486  Aromatic aldehyde <=> Aromatic acid
    R05235  4-Isopropylbenzaldehyde <=> p-Cumate

Orthology

K10618

p-cumic aldehyde dehydrogenase

LinkDB

DBGET integrated database retrieval system