KEGG   ORTHOLOGY: K10701
Entry
K10701                      KO                                     
Symbol
apc
Name
acetophenone carboxylase [EC:6.4.1.8]
Pathway
map00642  Ethylbenzene degradation
map01120  Microbial metabolism in diverse environments
map01220  Degradation of aromatic compounds
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00642 Ethylbenzene degradation
    K10701  apc; acetophenone carboxylase
Enzymes [BR:ko01000]
 6. Ligases
  6.4  Forming carbon-carbon bonds
   6.4.1  Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
    6.4.1.8  acetophenone carboxylase
     K10701  apc; acetophenone carboxylase
Other DBs
RN: R05453
GO: 0018524
Genes
EBA: c1A100(apc4) c1A102(apc3) c1A105(apc1) c1A200(apc2) c1A97(apc5)
ABRE: pbN1_00090(apcE) pbN1_00120(apcB)
RMAR: GBA65_17305 GBA65_17310
HAKZ: J0X25_19550 J0X25_19560 J0X25_19565
Reference
  Authors
Jobst B, Schuhle K, Linne U, Heider J
  Title
ATP-dependent carboxylation of acetophenone by a novel type of carboxylase.
  Journal
J Bacteriol 192:1387-94 (2010)
DOI:10.1128/JB.01423-09
  Sequence
LinkDB

KEGG   REACTION: R05453
Entry
R05453                      Reaction                               
Name
acetophenone:carbon-dioxide ligase (ADP-forming)
Definition
2 ATP + Acetophenone + HCO3- + H2O + H+ <=> 2 ADP + 2 Orthophosphate + 3-Oxo-3-phenylpropanoate
Equation
Reaction class
RC00002  C00002_C00008
RC00040  C07113_C07114
Enzyme
Pathway
rn00642  Ethylbenzene degradation
rn01120  Microbial metabolism in diverse environments
rn01220  Degradation of aromatic compounds
Orthology
K10701  acetophenone carboxylase [EC:6.4.1.8]
Other DBs
RHEA: 28650
LinkDB

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