KEGG ORTHOLOGY: K10738

ORTHOLOGY: K10738

Entry

K10738                      KO

Symbol

MCM9

Name

DNA helicase MCM9 [EC:5.6.2.4]

Disease

H00599

Ovarian dysgenesis

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins
    K10738  MCM9; DNA helicase MCM9
Enzymes [BR:ko01000]
5. Isomerases
  5.6  Isomerases altering macromolecular conformation
   5.6.2  Enzymes altering nucleic acid conformation
    5.6.2.4  DNA 3'-5' helicase
     K10738  MCM9; DNA helicase MCM9
DNA replication proteins [BR:ko03032]
Eukaryotic type
  DNA Replication Initiation Factors
   Other initiation factors
    K10738  MCM9; DNA helicase MCM9

Other DBs

GO:

0097362

Genes

HSA:	254394(MCM9)

PTR:	462969(MCM9)

PPS:	100975400(MCM9)

GGO:	101142876(MCM9)

PON:	100461848(MCM9)

NLE:	100605484(MCM9)

HMH:	116471461(MCM9)

MCC:	714711(MCM9)

MCF:	102133269(MCM9)

MTHB:

126953291

MNI:	105465507(MCM9)

CSAB:

103240484(MCM9)

CATY:

105581445(MCM9)

PANU:

101009408(MCM9)

TGE:	112623059(MCM9)

MLEU:

105540158(MCM9)

RRO:	104654177(MCM9)

RBB:	108544711(MCM9)

TFN:	117096996(MCM9)

PTEH:

111547286(MCM9)

CANG:

105508443(MCM9)

CJC:	100414376(MCM9)

SBQ:	101052943(MCM9)

CIMI:

108312894(MCM9)

CSYR:

103268221

MMUR:

105857021(MCM9)

LCAT:

123633211(MCM9)

PCOQ:

105815394(MCM9)

OGA:	100966826(MCM9)

MMU:	71567(Mcm9)

MCAL:

110303282(Mcm9)

MPAH:

110326485(Mcm9)

MCOC:

116075499(Mcm9)

ANU:	117724331(Mcm9)

MUN:	110557534(Mcm9)

CGE:	100762661(Mcm9)

MAUA:

101822842(Mcm9)

PROB:

127215120(Mcm9)

PLEU:

114692558(Mcm9)

MORG:

121449297(Mcm9)

MFOT:

126499003

AAMP:

119820596(Mcm9)

NGI:	103736293(Mcm9)

HGL:	101698921(Mcm9)

CPOC:

100733089(Mcm9)

CCAN:

109694790(Mcm9)

DORD:

105998176(Mcm9)

DSP:	122127099(Mcm9)

PLOP:

125357233(Mcm9)

NCAR:

124989726

MMMA:

107154976(Mcm9)

OCU:

100340330

OPI:	101531623(MCM9)

TUP:	102500225(MCM9)

GVR:	103599137(MCM9)

CFA:	484104(MCM9)

CLUD:

112644484(MCM9)

VVP:	112922758(MCM9)

VLG:	121484086(MCM9)

NPO:	129499940(MCM9)

AML:	100466906(MCM9)

UMR:	103663455(MCM9)

UAH:	113259395(MCM9)

UAR:	123792998(MCM9)

ELK:

111147567

LLV:

125102151

MPUF:

101684169(MCM9)

MNP:	132018124(MCM9)

MLK:	131833858(MCM9)

NVS:	122907146(MCM9)

ORO:	101379121(MCM9)

EJU:	114219462(MCM9)

ZCA:	113926942(MCM9)

MLX:	118000621(MCM9)

NSU:	110583381(MCM9)

LWW:	102749966(MCM9)

FCA:	101098953(MCM9)

PYU:	121029980(MCM9)

PCOO:

112862165(MCM9)

PBG:	122489926(MCM9)

PVIV:

125165464(MCM9)

LRUF:

124528244

PTG:	102969444(MCM9)

PPAD:

109248473(MCM9)

PUC:

125938851

AJU:

106968322

HHV:	120241102(MCM9)

BTA:	100139498(MCM9)

BOM:	102270787(MCM9)

BIU:	109563779(MCM9)

BBUB:

102416164(MCM9)

BBIS:

105004250(MCM9)

CHX:	102169871(MCM9)

OAS:	101123472(MCM9)

BTAX:

128053052(MCM9)

ODA:	120862440(MCM9)

CCAD:

122422925(MCM9)

MBEZ:

129560681(MCM9)

SSC:	100519693(MCM9)

CFR:	102524110(MCM9)

CBAI:

105077174(MCM9)

CDK:	105088349(MCM9)

VPC:	102526545(MCM9)

BACU:

103004756(MCM9)

BMUS:

118905095(MCM9)

LVE:	103080942(MCM9)

OOR:	101271898(MCM9)

DLE:	111165050(MCM9)

PCAD:

102983266(MCM9)

PSIU:

116763248(MCM9)

NASI:

112409175(MCM9)

ECB:	100072839(MCM9)

EPZ:	103559605(MCM9)

EAI:	106847011(MCM9)

MYB:	102245766(MCM9)

MYD:	102766721(MCM9)

MMYO:

118660526(MCM9)

MLF:	102425750(MCM9)

PKL:	118706159(MCM9)

EFUS:

103283570(MCM9)

MNA:	107526299(MCM9)

DRO:	112297039(MCM9)

SHON:

118986748(MCM9)

AJM:	119036856(MCM9)

PDIC:

114493801(MCM9)

PHAS:

123821353(MCM9)

MMF:	118620890(MCM9)

PPAM:

129067735(MCM9)

HAI:	109374591 109374596(MCM9)

RFQ:	117016898(MCM9)

PALE:

102886804(MCM9)

PGIG:

120609100(MCM9)

PVP:	105291169(MCM9)

RAY:	107515136(MCM9)

MJV:	108409433(MCM9)

TOD:	119252832(MCM9)

LAV:	100665082(MCM9)

TMU:

101346675

ETF:	101648246(MCM9)

DNM:	101444947(MCM9)

MDO:	100030189(MCM9)

GAS:	123247810(MCM9)

SHR:	100913268(MCM9)

AFZ:

127562154

PCW:

110197581

OAA:	100079522(MCM9)

GGA:	100857742(MCM9)

PCOC:

116240793(MCM9)

MGP:	100550074 104909820(MCM9)

CJO:	107311833(MCM9)

TPAI:

128079267(MCM9)

LMUT:

125689194(MCM9)

NMEL:

110395990(MCM9)

APLA:

101795650(MCM9)

ACYG:

106032404(MCM9)

CATA:

118244118(MCM9)

AFUL:

116488175(MCM9)

TGU:	100217657(MCM9)

LSR:	110476144(MCM9)

SCAN:

103822036(MCM9)

PMOA:

120512819(MCM9)

OTC:	121346199(MCM9)

GFR:	102038545(MCM9)

FAB:	101812818(MCM9)

OMA:	130251095(MCM9)

PHI:	102109040(MCM9)

PMAJ:

107202074(MCM9)

CCAE:

111927190(MCM9)

CCW:	104691069(MCM9)

CBRC:

103619289(MCM9)

ETL:	114066158(MCM9)

ZAB:	102064379(MCM9)

ACHL:

103802008

SVG:	106853464(MCM9)

MMEA:

130575223(MCM9)

HRT:	120749990(MCM9)

FPG:	101911688(MCM9)

FCH:	102047311(MCM9)

CLV:	102093939(MCM9)

EGZ:	104131966(MCM9)

NNI:	104008918(MCM9)

PCRI:

PLET:

EHS:

PCAO:

ACUN:

113478443(MCM9)

TALA:

104369010(MCM9)

PADL:

103918381(MCM9)

AFOR:

103907078(MCM9)

ACHC:

115351020(MCM9)

HALD:

104314045

HLE:	104843112(MCM9)

AGEN:

GCL:

CCRI:

CMAC:

BREG:

FGA:

GSTE:

LDI:

MNB:

OHA:	104338792(MCM9)

NNT:

104408738

SHAB:

115609609(MCM9)

DPUB:

104305230(MCM9)

PGUU:

104462348

ACAR:

104521927

CPEA:

104390107(MCM9)

AVIT:

104278874

CVF:	104284819(MCM9)

RTD:	128907133(MCM9)

CUCA:

104060464(MCM9)

TEO:

104380236

BRHI:

104494236

AAM:	106497961(MCM9)

AROW:

112972584(MCM9)

NPD:	112949438(MCM9)

TGT:

104568683

DNE:	112997474(MCM9)

SCAM:

104148472(MCM9)

ASN:	102377681(MCM9)

AMJ:	102575469(MCM9)

CPOO:

109311971(MCM9)

GGN:	109299556(MCM9)

PSS:	102448967(MCM9)

CMY:	102943379(MCM9)

CCAY:

125634224(MCM9)

DCC:	119852747(MCM9)

CPIC:

101948604(MCM9)

TST:	117874988(MCM9)

CABI:

116824908(MCM9)

MRV:	120401379(MCM9)

ACS:	100553098(mcm9)

ASAO:

132760920(MCM9)

PVT:	110083609(MCM9)

SUND:

121919278(MCM9)

PBI:	103054389 103057984(MCM9)

PMUR:

107299757(MCM9)

CTIG:

120309821(MCM9)

TSR:	106544537(MCM9)

PGUT:

117666219(MCM9)

APRI:

131193125(MCM9)

PTEX:

113439551(MCM9)

VKO:	123021195(MCM9)

PMUA:

114594088(MCM9)

PRAF:

128410481(MCM9)

ZVI:	118082164(MCM9)

HCG:	128339304(MCM9)

GJA:	107108607(MCM9)

STOW:

125430262(MCM9)

EMC:	129327661(MCM9)

XLA:	431809(mcm9.L)

XTR:	100490403(mcm9)

NPR:	108792658(MCM9)

RTEM:

120937257(MCM9)

BBUF:

120998298(MCM9)

BGAR:

122934393(MCM9)

MUO:	115466956(MCM9)

GSH:	117357054(MCM9)

DRE:	555610(mcm9)

SRX:	107727573 107743310

SANH:

107678857 107697136

SGH:	107549683 107603056

CCAR:

109100500

CAUA:

113044660 113113313 113120491

CGIB:

127983465

PTET:

122324340(mcm9)

LROH:

127182532(mcm9)

OMC:	131527607(mcm9)

PPRM:

120493310(mcm9)

RKG:	130102967(mcm9)

MAMB:

125278408(mcm9)

CIDE:

127502810

MASI:

127416040

TROS:

130566449(mcm9)

TDW:	130433857(mcm9)

MANU:

129429866(mcm9)

IPU:

108257878

IFU:	128601009(mcm9)

PHYP:

113531743(mcm9)

SMEO:

124377414(mcm9)

TFD:	113648335(mcm9)

TVC:	132843099(mcm9)

AMEX:

103041384(mcm9)

CMAO:

118816186(mcm9)

EEE:	113572252(mcm9)

CHAR:

105901303(mcm9)

TRU:	101068427(mcm9)

TFS:	130516636(mcm9)

TNG:	GSTEN00013950G001

LCO:	104939751(mcm9)

NCC:	104959201(mcm9)

TBEN:

117498452(mcm9)

CGOB:

115003790(mcm9) 115003967

PGEO:

117440329(mcm9)

GACU:

117532381(mcm9)

EMAC:

134876512(mcm9)

ELY:	117270667(mcm9)

EFO:	125897353(mcm9)

PLEP:

121955492(mcm9)

SLUC:

116053489(mcm9)

ECRA:

117961675(mcm9)

ESP:	116705876(mcm9)

PFLV:

114573513

GAT:	120808224(mcm9)

PPUG:

119194520(mcm9)

AFB:	129106752(mcm9)

CLUM:

117727288(mcm9)

PSWI:

130200316(mcm9)

MSAM:

119908651(mcm9)

SCHU:

122863219(mcm9)

CUD:	121521896(mcm9)

ALAT:

119012670(mcm9)

MZE:	101471131(mcm9)

ONL:	100700864(mcm9)

OAU:	116321759(mcm9)

OLA:	101172783(mcm9)

OML:	112158225(mcm9)

CSAI:

133464927(mcm9)

XMA:	102221584(mcm9)

XCO:	114158919(mcm9)

XHE:	116733844 116734254(mcm9)

PRET:

103458001(mcm9)

PFOR:

103150867(mcm9)

PLAI:

106944837(mcm9)

PMEI:

106921492(mcm9)

GAF:	122824843(mcm9)

PPRL:

129369238(mcm9)

CVG:	107094793(mcm9)

CTUL:

119773539(mcm9)

GMU:	124881488(mcm9)

NFU:	107395990(mcm9)

KMR:	108245668(mcm9)

ALIM:

106529778(mcm9)

NWH:	119418764(mcm9)

AOCE:

111586609

MCEP:

124998595(mcm9)

CSEM:

103380606(mcm9)

POV:	109632550(mcm9)

SSEN:

122784257(mcm9)

HHIP:

117758623(mcm9)

HSP:	118099537(mcm9)

SMAU:

118289875(mcm9)

LCF:

108899342

SDU:	111240208(mcm9)

SLAL:

111652535(mcm9)

XGL:	120789186(mcm9)

HCQ:	109531740(mcm9)

SSCV:

125990173

SBIA:

133496618(mcm9)

PEE:	133416865(mcm9)

PTAO:

133468300(mcm9)

BPEC:

110156606(mcm9)

MALB:

109966563(mcm9)

BSPL:

114849250(mcm9)

SJO:	128376894(mcm9)

SASA:

106571380

STRU:

115174840

OTW:

112250146

OMY:	110529584(mcm9)

OGO:

123990729

ONE:	115107729(mcm9)

OKI:

109900722

OKE:	118386603(mcm9) 118398684

SALP:

111954563

SNH:	120024416(mcm9)

CCLU:

121552685

ELS:	105017951(mcm9)

SFM:	108928473(mcm9)

PKI:	111836147(mcm9)

AANG:

118229150(mcm9)

LOC:	102698672(mcm9)

PSPA:

121317304(mcm9)

ARUT:

117410918

PSEX:

120525399(mcm9)

LCM:	102365066(MCM9)

CMK:	103182591(mcm9)

CPLA:

122545330(mcm9)

HOC:	132832703(mcm9)

LERI:

129697308(mcm9)

PMRN:

116953381(MCM9)

LRJ:	133351298(MCM9)

BFO:

BBEL:

CIN:

SCLV:

SPU:

LPIC:

APLC:

AJC:

CLON:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AFUN:

AAG:

AALB:

CQU:	CpipJ_CPIJ008363

CPII:

CNS:

BCOO:

ACER:

ALAB:

ADR:

AFLR:

BBIF:

BVK:

BVAN:

BAFF:

BPYO:

BPAS:

FVI:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

DQU:

CFO:

FEX:

LHU:

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

TPRE:

LHT:

LBD:

MDL:

CGLO:

FAS:

DAM:

AGIF:

CINS:

VCAN:

CCIN:

DSM:

NPT:

NFB:

NLO:

NVG:

AROA:

TCA:

DPA:

SOY:

ATD:

CSET:

AGB:

LDC:

NVL:

APLN:

PPYR:

OTU:

BMOR:

BMAN:

DPL:	KGM_202602

BANY:

MJU:

NIQ:

VCD:

PMAC:

PPOT:

PXU:

PRAP:

PBX:

PNAP:

ZCE:

CCRC:

LSIN:

HAW:

HZE:

TNL:

SLIU:

OFU:

PXY:	105390665 105395371

PGW:

CCRN:

API:

DNX:

AGS:

RMD:

ACOO:

DVT:

BTAB:

CLEC:

HHAL:

NLU:

HVI:

MQU:	129002231 129002307

PHU:	Phum_PHUM307490

FOC:

TPAL:

ZNE:

CSEC:

SGRE:

BROR:

IEL:

FCD:

DPX:	DAPPUDRAFT_322108

DMK:

DPZ:

PVM:

PJA:

PCHN:

PMOO:

PCLA:

CQD:	128684224 128684226

PTRU:

ESN:

HAZT:

EAF:

LSM:

TCF:

PPOI:

DSV:

RMP:

CSCU:

PTEP:

UDV:

SDM:

TSP:

HRO:	HELRODRAFT_74084

LGI:	LOTGIDRAFT_121966

PCAN:

112559487

BGT:

106073959

GAE:	121366157 121382318

HRF:

HRJ:

CRG:

CANU:

OED:

MYI:

PMAX:

MCAF:

RPHI:

OSN:

LAK:

SMM:	Smp_151560

SHX:	MS3_00005896(MCM9)

OVI:	T265_12914

EGL:

NVE:

EPA:

ATEN:

ADF:

AMIL:

PDAM:

SPIS:

DGT:

XEN:

HMG:

HSY:

TAD:	TRIADDRAFT_31981

ATH:	AT2G14050(MCM9)

ALY:

9319886

CRB:

17891745

CSAT:

104747295 104766662 104793587

EUS:	EUTSA_v10022581mg

BRP:

103860392

BNA:	106394868 106439747

BOE:

RSZ:

THJ:

CPAP:

CIT:

CIC:	CICLE_v10029860mg

PVY:

MINC:

TCC:

GRA:

GHI:	107929048 121210809

GAB:

HSYR:

DZI:

EGR:

GMX:

GSJ:

PVU:	PHAVU_006G204900g

VRA:

VAR:

VUN:

CCAJ:

APRC:

MTR:

TPRA:

CAM:

PSAT:

VVO:

LJA:	Lj6g3v2204750.1(Lj6g3v2204750.1) Lj6g3v2204750.2(Lj6g3v2204750.2)

ADU:

107468766

AIP:

107624538

AHF:	112714831 112782781

LANG:

109334605

PCIN:

129305894

QSA:	O6P43_012385

FVE:

RCN:

PPER:

PMUM:

PAVI:

PDUL:

MDM:

MSYL:

PXB:

ZJU:

MNT:

CSAV:

CSV:

CMO:

BHJ:

MCHA:

CMAX:

CMOS:

CPEP:

RCU:

JCU:

HBR:

MESC:

POP:

PEU:

PALZ:

JRE:

CILL:

CAVE:

QSU:

QLO:

TWL:

VVI:

VRI:

SLY:

SPEN:

SOT:

SSTN:

SDUL:

CANN:

LBB:

NTA:	107782873 107819758

NSY:

NTO:

NAU:

INI:

ITR:

SIND:

OEU:

EGT:

SSPL:

SMIL:

SHIS:

APAN:

HAN:

ECAD:

LSV:

CCAV:

DCR:

CSIN:

RVL:

AEW:	130755939 130774378

BVG:

104904228

SOE:	110802504 130472303

CQI:

MOF:

NNU:

MING:

TSS:

PSOM:

113285351 113285353 113311854

OSA:

4340503

DOSA:

Os06t0218500-01(Os06g0218500)

OBR:

OGL:

BDI:

ATS:

TDC:	119330993 119342065

TAES:

123150790 123161027 123166143

TUA:	125523460 125523511

LPER:

127317687

LRD:	124672097 124708823

SBI:

ZMA:

SITA:

SVS:

PVIR:

120669525 120693857 120703564

PHAI:

PDA:

EGU:

MUS:

ZOF:	122019616 122051171

DCT:

PEQ:

AOF:

MSIN:

NCOL:

ATR:

SMO:	SELMODRAFT_1994 SELMODRAFT_427521

PPP:

112285803

CSL:	COCSUDRAFT_46180

CVR:	CHLNCDRAFT_34046

OLU:	OSTLU_1571

OTA:	OT_ostta05g01680

BPG:	Bathy06g02810

MIS:	MICPUN_113396(MCM9)

MPP:	MICPUCDRAFT_36911(JGI:MicpuC2_36911) MICPUCDRAFT_55301(MCM9)

CME:	CYME_CMO137C

GSL:	Gasu_05680

CCP:	CHC_T00008889001

EIN:	Eint_070430

EHE:	EHEL_070460

ERO:	EROM_070440

NCE:	NCER_101540

MBR:	MONBRDRAFT_32709

SRE:	PTSG_08033

DDI:	DDB_G0286035(mcm9)

DPP:	DICPUDRAFT_34376

DFA:	DFA_04835(mcm9)

EHI:	EHI_076880(40.t00023)

EDI:	EDI_292100

EIV:	EIN_097740

TAN:

TA08800

TPV:

TP04_0510

TOT:	TOT_040000407

BEQ:	BEWA_008210

BMIC:

BMR1_02g03705

BBIG:

BBBOND_0200460

TET:	TTHERM_00703910

PTM:	GSPATT00009368001

PTI:	PHATRDRAFT_981

FCY:	FRACYDRAFT_156569

TPS:	THAPSDRAFT_37362

AAF:	AURANDRAFT_35962

PIF:	PITG_04940

PSOJ:

PHYSODRAFT_295880

SPAR:

SPRG_13186

EHX:	EMIHUDRAFT_456757 EMIHUDRAFT_464628

GTT:	GUITHDRAFT_86289(MCM9)

NGR:	NAEGRDRAFT_727

» show all

Reference

PMID:22771115

Authors

Nishimura K, Ishiai M, Horikawa K, Fukagawa T, Takata M, Takisawa H, Kanemaki MT

Title

Mcm8 and Mcm9 form a complex that functions in homologous recombination repair induced by DNA interstrand crosslinks.

Journal

Mol Cell 47:511-22 (2012)
DOI:10.1016/j.molcel.2012.05.047

Sequence

[hsa:254394]

Reference

PMID:23401855

Authors

Park J, Long DT, Lee KY, Abbas T, Shibata E, Negishi M, Luo Y, Schimenti JC, Gambus A, Walter JC, Dutta A

Title

The MCM8-MCM9 complex promotes RAD51 recruitment at DNA damage sites to facilitate homologous recombination.

Journal

Mol Cell Biol 33:1632-44 (2013)
DOI:10.1128/MCB.01503-12

LinkDB

DBGET integrated database retrieval system