KEGG   ORTHOLOGY: K11817
Entry
K11817                      KO                                     
Symbol
AAO1_2
Name
indole-3-acetaldehyde oxidase [EC:1.2.3.7]
Pathway
map00380  Tryptophan metabolism
map01100  Metabolic pathways
Reaction
R02681  indole-3-acetaldehyde:oxygen oxidoreductase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00380 Tryptophan metabolism
    K11817  AAO1_2; indole-3-acetaldehyde oxidase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.3  With oxygen as acceptor
    1.2.3.7  indole-3-acetaldehyde oxidase
     K11817  AAO1_2; indole-3-acetaldehyde oxidase
Other DBs
GO: 0050302
Genes
ATH: AT3G43600(AAO2) AT5G20960(AO1)
ALY: 9310093
CRB: 17884094
CSAT: 104706450 104736175 104770481 104780236 104790642
EUS: EUTSA_v10012448mg
BRP: 103845621 103848036 103851392 103873635
BNA: 106347703 106371701 106376414 106406426 106410244 106425715
BOE: 106317854 106326884 106326885 106335357
RSZ: 108812376 108832706 108842248 108861735
THJ: 104799592 104799593
OSA: 4334382(AO-2) 4348072(AO-1)
DOSA: Os03g0790900 Os10g0138100
OBR: 102704964
OGL: 127765440 127785645
BDI: 100822277 100822898 100836900
ATS: 109747740 109747741 109747742 109752661 109765340
TDC: 119303471 119303472 119303473 119303474 119303476 119303477 119312128 119312132 119345299
TAES: 123105337 123105340 123105341 123105342 123105343 123105344 123113606 123113607 123113609 123123127 123123129 123123132 123123133
TUA: 125510893 125510896 125510934 125546255
HVG: 123452610 123452611 123452612
LPER: 127292476 127293769 127293770 127314462
LRD: 124685088 124690068 124703720 124704526
SBI: 8061191 8084125 8084128
ZMA: 103644157 542228 542229
MFLO: 136474344 136474439 136477452 136477528 136516582 136516590 136516599
SITA: 101754702 101755113 101756196 101764191
SVS: 117838076 117838077 117839666
PVIR: 120649504 120649505 120691959 120693301
PHAI: 112878335
PAUA: 133913491 133913493 133915283 133915284
TANG: 140758637 140758729
ZOF: 122001229 122005521 122008453 122014832 122014905 122014911 122046391 122046414
ACAK: 137947966 137948210
 » show all
Reference
PMID:12226218
  Authors
Koshiba T, Saito E, Ono N, Yamamoto N, Sato M
  Title
Purification and Properties of Flavin- and Molybdenum-Containing Aldehyde Oxidase from Coleoptiles of Maize.
  Journal
Plant Physiol 110:781-789 (1996)
DOI:10.1104/pp.110.3.781
  Sequence
[zma:542228]
Reference
PMID:9615466
  Authors
Sekimoto H, Seo M, Kawakami N, Komano T, Desloire S, Liotenberg S, Marion-Poll A, Caboche M, Kamiya Y, Koshiba T
  Title
Molecular cloning and characterization of aldehyde oxidases in Arabidopsis thaliana.
  Journal
Plant Cell Physiol 39:433-42 (1998)
DOI:10.1093/oxfordjournals.pcp.a029387
  Sequence
[ath:AT5G20960 AT3G43600]
Reference
PMID:10423535
  Authors
Akaba S, Seo M, Dohmae N, Takio K, Sekimoto H, Kamiya Y, Furuya N, Komano T, Koshiba T
  Title
Production of homo- and hetero-dimeric isozymes from two aldehyde oxidase genes of Arabidopsis thaliana.
  Journal
J Biochem 126:395-401 (1999)
DOI:10.1093/oxfordjournals.jbchem.a022463
LinkDB

KEGG   ORTHOLOGY: K22417
Entry
K22417                      KO                                     
Symbol
AAO4
Name
benzaldehyde dehydrogenase (NAD+) / indole-3-acetaldehyde oxidase [EC:1.2.1.28 1.2.3.7]
Pathway
map00380  Tryptophan metabolism
map01100  Metabolic pathways
Reaction
R02681  indole-3-acetaldehyde:oxygen oxidoreductase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00380 Tryptophan metabolism
    K22417  AAO4; benzaldehyde dehydrogenase (NAD+) / indole-3-acetaldehyde oxidase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.1  With NAD+ or NADP+ as acceptor
    1.2.1.28  benzaldehyde dehydrogenase (NAD+)
     K22417  AAO4; benzaldehyde dehydrogenase (NAD+) / indole-3-acetaldehyde oxidase
   1.2.3  With oxygen as acceptor
    1.2.3.7  indole-3-acetaldehyde oxidase
     K22417  AAO4; benzaldehyde dehydrogenase (NAD+) / indole-3-acetaldehyde oxidase
Other DBs
GO: 0018479 0050302
Genes
ATH: AT1G04580(AO4)
ALY: 9328289
CRB: 17900582
CSAT: 104738981 104762389
EUS: EUTSA_v10006570mg
BRP: 103844240
BNA: 106371001 106402186
BOE: 106295510
RSZ: 108815136 108837371
Reference
PMID:19297586
  Authors
Ibdah M, Chen YT, Wilkerson CG, Pichersky E
  Title
An aldehyde oxidase in developing seeds of Arabidopsis converts benzaldehyde to benzoic Acid.
  Journal
Plant Physiol 150:416-23 (2009)
DOI:10.1104/pp.109.135848
  Sequence
[ath:AT1G04580]
LinkDB

KEGG   ENZYME: 1.2.3.7
Entry
EC 1.2.3.7                  Enzyme                                 
Name
indole-3-acetaldehyde oxidase;
indoleacetaldehyde oxidase;
IAAld oxidase;
AO1;
indole-3-acetaldehyde:oxygen oxidoreductase
Class
Oxidoreductases;
Acting on the aldehyde or oxo group of donors;
With oxygen as acceptor
Sysname
(indol-3-yl)acetaldehyde:oxygen oxidoreductase
Reaction(IUBMB)
(indol-3-yl)acetaldehyde + H2O + O2 = (indol-3-yl)acetate + H2O2 [RN:R02681]
Reaction(KEGG)
R02681
Substrate
(indol-3-yl)acetaldehyde;
H2O [CPD:C00001];
O2 [CPD:C00007]
Product
(indol-3-yl)acetate [CPD:C00954];
H2O2 [CPD:C00027]
Comment
A hemoprotein. This enzyme is an isoform of aldehyde oxidase (EC 1.2.3.1). It has a preference for aldehydes having an indole-ring structure as substrate [6,7]. It may play a role in plant hormone biosynthesis as its activity is higher in the auxin-overproducing mutant, super-root1, than in wild-type Arabidopsis thaliana [7]. While (indol-3-yl)acetaldehyde is the preferred substrate, it also oxidizes indole-3-carbaldehyde and acetaldehyde, but more slowly. The enzyme from maize contains FAD, iron and molybdenum [4].
History
EC 1.2.3.7 created 1984, modified 2004, modified 2006
Pathway
ec00380  Tryptophan metabolism
ec01100  Metabolic pathways
Orthology
K11817  indole-3-acetaldehyde oxidase
K22417  benzaldehyde dehydrogenase (NAD+) / indole-3-acetaldehyde oxidase
Genes
ATH: AT1G04580(AO4) AT3G43600(AAO2) AT5G20960(AO1)
ALY: 9310093 9328289
CRB: 17884094 17900582
CSAT: 104706450 104736175 104738981 104762389 104770481 104780236 104790642
EUS: EUTSA_v10006570mg EUTSA_v10012448mg
BRP: 103844240 103845621 103848036 103851392 103873635
BNA: 106347703 106371001 106371701 106376414 106402186 106406426 106410244 106425715
BOE: 106295510 106317854 106326884 106326885 106335357
RSZ: 108812376 108815136 108832706 108837371 108842248 108861735
THJ: 104799592 104799593
OSA: 4334382(AO-2) 4348072(AO-1)
DOSA: Os03g0790900 Os10g0138100
OBR: 102704964
OGL: 127765440 127785645
BDI: 100822277 100822898 100836900
ATS: 109747740 109747741 109747742 109752661 109765340
TDC: 119303471 119303472 119303473 119303474 119303476 119303477 119312128 119312132 119345299
TAES: 123105337 123105340 123105341 123105342 123105343 123105344 123113606 123113607 123113609 123123127 123123129 123123132 123123133
TUA: 125510893 125510896 125510934 125546255
HVG: 123452610 123452611 123452612
LPER: 127292476 127293769 127293770 127314462
LRD: 124685088 124690068 124703720 124704526
SBI: 8061191 8084125 8084128
ZMA: 103644157 542228 542229
MFLO: 136474344 136474439 136477452 136477528 136516582 136516590 136516599
SITA: 101754702 101755113 101756196 101764191
SVS: 117838076 117838077 117839666
PVIR: 120649504 120649505 120691959 120693301
PHAI: 112878335
PAUA: 133913491 133913493 133915283 133915284
TANG: 140758637 140758729
ZOF: 122001229 122005521 122008453 122014832 122014905 122014911 122046391 122046414
ACAK: 137947966 137948210
 » show all
Reference
1  [PMID:16660220]
  Authors
Bower PJ, Brown HM, Purves WK.
  Title
Cucumber Seedling Indoleacetaldehyde Oxidase.
  Journal
Plant Physiol 61:107-110 (1978)
DOI:10.1104/pp.61.1.107
Reference
2
  Authors
Miyata S, Suzuki Y, Kamisaka S, Masuda Y.
  Title
Indole-3-acetaldehyde oxidase of pea-seedlings.
  Journal
Physiol Plant 51:402-406 (1981)
Reference
3
  Authors
Rajagopal R.
  Title
Metabolism of indole-3-acetaldehyde. III. Some characteristics of the aldehyde oxidase of Avena coleoptiles.
  Journal
Physiol Plant 24:272-281 (1971)
Reference
4  [PMID:12226218]
  Authors
Koshiba T, Saito E, Ono N, Yamamoto N, Sato M
  Title
Purification and Properties of Flavin- and Molybdenum-Containing Aldehyde Oxidase from Coleoptiles of Maize.
  Journal
Plant Physiol 110:781-789 (1996)
DOI:10.1104/pp.110.3.781
  Sequence
[zma:542228]
Reference
5  [PMID:12231908]
  Authors
Koshiba T, Matsuyama H.
  Title
An in Vitro System of Indole-3-Acetic Acid Formation from Tryptophan in Maize (Zea mays) Coleoptile Extracts.
  Journal
Plant Physiol 102:1319-1324 (1993)
DOI:10.1104/pp.102.4.1319
Reference
6  [PMID:9615466]
  Authors
Sekimoto H, Seo M, Kawakami N, Komano T, Desloire S, Liotenberg S, Marion-Poll A, Caboche M, Kamiya Y, Koshiba T
  Title
Molecular cloning and characterization of aldehyde oxidases in Arabidopsis thaliana.
  Journal
Plant Cell Physiol 39:433-42 (1998)
DOI:10.1093/oxfordjournals.pcp.a029387
  Sequence
[ath:AT5G20960 AT3G43600]
Reference
7  [PMID:9489015]
  Authors
Seo M, Akaba S, Oritani T, Delarue M, Bellini C, Caboche M, Koshiba T.
  Title
Higher activity of an aldehyde oxidase in the auxin-overproducing superroot1 mutant of Arabidopsis thaliana.
  Journal
Plant Physiol 116:687-93 (1998)
DOI:10.1104/pp.116.2.687
  Sequence
[ath:AT5G20960]
Other DBs
ExplorEnz - The Enzyme Database: 1.2.3.7
IUBMB Enzyme Nomenclature: 1.2.3.7
ExPASy - ENZYME nomenclature database: 1.2.3.7
BRENDA, the Enzyme Database: 1.2.3.7
CAS: 66082-22-2
LinkDB

KEGG   REACTION: R02681
Entry
R02681                      Reaction                               
Name
indole-3-acetaldehyde:oxygen oxidoreductase
Definition
Indole-3-acetaldehyde + Oxygen + H2O <=> Indole-3-acetate + Hydrogen peroxide
Equation
C00637 + C00007 + C00001 <=> C00954 + C00027
Reaction class
RC00080  C00637_C00954
RC02755  C00007_C00027
Enzyme
1.2.3.7
Pathway
rn00380  Tryptophan metabolism
rn01100  Metabolic pathways
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.3  With oxygen as acceptor
    1.2.3.7
     R02681  Indole-3-acetaldehyde + Oxygen + H2O <=> Indole-3-acetate + Hydrogen peroxide
Orthology
K11817  indole-3-acetaldehyde oxidase [EC:1.2.3.7]
K22417  benzaldehyde dehydrogenase (NAD+) / indole-3-acetaldehyde oxidase [EC:1.2.1.28 1.2.3.7]
Other DBs
RHEA: 16280
LinkDB

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