KEGG   ORTHOLOGY: K11868
Entry
K11868                      KO                                     
Symbol
CYP71A13
Name
indoleacetaldoxime dehydratase [EC:4.8.1.3]
Pathway
map00380  Tryptophan metabolism
map01100  Metabolic pathways
Reaction
R04093  3-indoleacetaldoxime hydro-lyase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00380 Tryptophan metabolism
    K11868  CYP71A13; indoleacetaldoxime dehydratase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450
    K11868  CYP71A13; indoleacetaldoxime dehydratase
Enzymes [BR:ko01000]
 4. Lyases
  4.8  Nitrogen-oxygen lyases
   4.8.1  Hydro-lyases
    4.8.1.3  indoleacetaldoxime dehydratase
     K11868  CYP71A13; indoleacetaldoxime dehydratase
Cytochrome P450 [BR:ko00199]
 Cytochrome P450, plant type
  CYP71 family
   K11868  CYP71A13; indoleacetaldoxime dehydratase
Other DBs
GO: 0047720
Genes
ATH: AT1G11610(CYP71A18) AT2G30750(CYP71A12) AT2G30770(CYP71A13)
ALY: 9315346 9317198
CRB: 17887687 17887753 17889762 17890046
CSAT: 104700401 104700403 104704341 104704342 104749803 104749804 104749806 104786560 104786562 104786563
BRP: 103857338
BNA: 106403189 106437575
BOE: 106328873
RSZ: 108847161
Reference
PMID:17573535 (CYP71A13)
  Authors
Nafisi M, Goregaoker S, Botanga CJ, Glawischnig E, Olsen CE, Halkier BA, Glazebrook J
  Title
Arabidopsis cytochrome P450 monooxygenase 71A13 catalyzes the conversion of indole-3-acetaldoxime in camalexin synthesis.
  Journal
Plant Cell 19:2039-52 (2007)
DOI:10.1105/tpc.107.051383
  Sequence
[ath:AT2G30770]
LinkDB

KEGG   ENZYME: 4.8.1.3
Entry
EC 4.8.1.3                  Enzyme                                 
Name
indoleacetaldoxime dehydratase;
indoleacetaldoxime hydro-lyase;
3-indoleacetaldoxime hydro-lyase;
indole-3-acetaldoxime hydro-lyase;
indole-3-acetaldehyde-oxime hydro-lyase;
(indol-3-yl)acetaldehyde-oxime hydro-lyase
Class
Lyases;
Nitrogen-oxygen lyases;
Hydro-lyases
Sysname
(indol-3-yl)acetaldehyde-oxime hydro-lyase [(indol-3-yl)acetonitrile-forming]
Reaction(IUBMB)
(indol-3-yl)acetaldehyde oxime = (indol-3-yl)acetonitrile + H2O [RN:R04093]
Reaction(KEGG)
R04093
Substrate
(indol-3-yl)acetaldehyde oxime [CPD:C02937]
Product
(indol-3-yl)acetonitrile [CPD:C02938];
H2O [CPD:C00001]
History
EC 4.8.1.3 created 1965 as EC 4.2.1.29, transferred 2004 to EC 4.99.1.6, transferred 2021 to EC 4.8.1.3
Pathway
ec00380  Tryptophan metabolism
ec01100  Metabolic pathways
Orthology
K11868  indoleacetaldoxime dehydratase
Genes
ATH: AT1G11610(CYP71A18) AT2G30750(CYP71A12) AT2G30770(CYP71A13)
ALY: 9315346 9317198
CRB: 17887687 17887753 17889762 17890046
CSAT: 104700401 104700403 104704341 104704342 104749803 104749804 104749806 104786560 104786562 104786563
BRP: 103857338
BNA: 106403189 106437575
BOE: 106328873
RSZ: 108847161
Reference
1  [PMID:14099566]
  Authors
KUMAR SA, MAHADEVAN S.
  Title
3-INDOLEACETALDOXIME HYDRO-LYASE: A PYRIDOXAL-5'-PHOSPHATE ACTIVATED ENZYME.
  Journal
Arch Biochem Biophys 103:516-8 (1963)
DOI:10.1016/0003-9861(63)90446-6
Reference
2
  Authors
Mahadevan S.
  Title
Conversion of 3-indoleacetoxime to 3-indoleacetonitrile by plants.
  Journal
Arch Biochem Biophys 100:557-558 (1963)
Other DBs
ExplorEnz - The Enzyme Database: 4.8.1.3
IUBMB Enzyme Nomenclature: 4.8.1.3
ExPASy - ENZYME nomenclature database: 4.8.1.3
BRENDA, the Enzyme Database: 4.8.1.3
CAS: 9024-27-5
LinkDB

KEGG   REACTION: R04093
Entry
R04093                      Reaction                               
Name
3-indoleacetaldoxime hydro-lyase
Definition
Indole-3-acetaldehyde oxime <=> 3-Indoleacetonitrile + H2O
Equation
C02937 <=> C02938 + C00001
Reaction class
RC01076  C02937_C02938
Enzyme
4.8.1.3
Pathway
rn00380  Tryptophan metabolism
rn01100  Metabolic pathways
Brite
Enzymatic reactions [BR:br08201]
 4. Lyase reactions
  4.8  Nitrogen-oxygen lyases
   4.8.1  Hydro-lyases
    4.8.1.3
     R04093  Indole-3-acetaldehyde oxime <=> 3-Indoleacetonitrile + H2O
Orthology
K11868  indoleacetaldoxime dehydratase [EC:4.8.1.3]
Other DBs
RHEA: 23159
LinkDB

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