Entry
Symbol
ptlA
Name
Pathway
map00909 Sesquiterpenoid and triterpenoid biosynthesis
map00998 Biosynthesis of various antibiotics
map01110 Biosynthesis of secondary metabolites
Module
M00819 Pentalenolactone biosynthesis, farnesyl-PP => pentalenolactone
Reaction
R02305 2-trans,6-trans-farnesyldiphosphate diphosphate-lyase (cyclizing, pentalenene-forming)
Brite
KEGG Orthology (KO) [BR:ko00001 ]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
00909 Sesquiterpenoid and triterpenoid biosynthesis
K12250 ptlA; pentalenene synthase
09110 Biosynthesis of other secondary metabolites
00998 Biosynthesis of various antibiotics
K12250 ptlA; pentalenene synthase
Enzymes [BR:ko01000 ]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.3 Acting on phosphates
4.2.3.7 pentalenene synthase
K12250 ptlA; pentalenene synthase
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Genes
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Taxonomy UniProt
Reference
Authors
Cane DE, Sohng JK, Lamberson CR, Rudnicki SM, Wu Z, Lloyd MD, Oliver JS, Hubbard BR
Title
Pentalenene synthase. Purification, molecular cloning, sequencing, and high-level expression in Escherichia coli of a terpenoid cyclase from Streptomyces UC5319.
Journal
Sequence
Reference
Authors
Tetzlaff CN, You Z, Cane DE, Takamatsu S, Omura S, Ikeda H
Title
A gene cluster for biosynthesis of the sesquiterpenoid antibiotic pentalenolactone in Streptomyces avermitilis.
Journal
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