Entry
Symbol
GCK
Name
Pathway
map00520 Amino sugar and nucleotide sugar metabolism
map00524 Neomycin, kanamycin and gentamicin biosynthesis
map01110 Biosynthesis of secondary metabolites
map01120 Microbial metabolism in diverse environments
map01250 Biosynthesis of nucleotide sugars
map04950 Maturity onset diabetes of the young
map05230 Central carbon metabolism in cancer
Module
M00001 Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
M00549 UDP-Glc biosynthesis, Glc => UDP-Glc
Reaction
R00299 ATP:D-glucose 6-phosphotransferase
R01600 ATP:beta-D-glucose 6-phosphotransferase
R01786 ATP:alpha-D-glucose 6-phosphotransferase
Disease
H00409 Type 2 diabetes mellitus
H00410 Maturity onset diabetes of the young (MODY)
H00512 Permanent neonatal diabetes mellitus
H01267 Familial hyperinsulinemic hypoglycemia
Brite
KEGG Orthology (KO) [BR:ko00001 ]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
K12407 GCK; glucokinase
00052 Galactose metabolism
K12407 GCK; glucokinase
00500 Starch and sucrose metabolism
K12407 GCK; glucokinase
09107 Glycan biosynthesis and metabolism
00520 Amino sugar and nucleotide sugar metabolism
K12407 GCK; glucokinase
09110 Biosynthesis of other secondary metabolites
00521 Streptomycin biosynthesis
K12407 GCK; glucokinase
00524 Neomycin, kanamycin and gentamicin biosynthesis
K12407 GCK; glucokinase
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
K12407 GCK; glucokinase
04910 Insulin signaling pathway
K12407 GCK; glucokinase
04922 Glucagon signaling pathway
K12407 GCK; glucokinase
04917 Prolactin signaling pathway
K12407 GCK; glucokinase
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
K12407 GCK; glucokinase
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
K12407 GCK; glucokinase
04950 Maturity onset diabetes of the young
K12407 GCK; glucokinase
Enzymes [BR:ko01000 ]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.2 glucokinase
K12407 GCK; glucokinase
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Reference
Authors
Iynedjian PB
Title
Molecular physiology of mammalian glucokinase.
Journal
LinkDB
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