KEGG   ORTHOLOGY: K12451
Entry
K12451                      KO                                     
Symbol
UER1
Name
3,5-epimerase/4-reductase [EC:5.1.3.- 1.1.1.-]
Pathway
map00520  Amino sugar and nucleotide sugar metabolism
map00523  Polyketide sugar unit biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
map01250  Biosynthesis of nucleotide sugars
Reaction
R08704  UDP-4-dehydro-6-deoxy-glucose 3,5-epimerase
R08705  UDP-L-rhamnose:NADP+ 4-oxidoreductase
R08935  dTDP-6-deoxy-L-mannose:NADP+ 4-oxidoreductase (3,5-epimerizing)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00520 Amino sugar and nucleotide sugar metabolism
    K12451  UER1; 3,5-epimerase/4-reductase
  09109 Metabolism of terpenoids and polyketides
   00523 Polyketide sugar unit biosynthesis
    K12451  UER1; 3,5-epimerase/4-reductase
Genes
ATH: AT1G63000(NRS/ER)
ALY: 9322509
CRB: 17895890
CSAT: 104703912 104714644 104752964
EUS: EUTSA_v10023613mg
BRP: 103838351 103871990
BNA: 106366534 106430227 106445572 111216246
BOE: 106292668 106312864
RSZ: 108828721 108840297 130510578
THJ: 104809430 104823569
CPAP: 110817577
CIT: 102628237
CIC: CICLE_v10021340mg
PVY: 116142897
MINC: 123204860 123211219
TCC: 18606429
GRA: 105789163
GHI: 107929277 107963680
GAB: 108483598
HSYR: 120138216 120163579
DZI: 111277638 111290886 111306008
EGR: 104441810
GMX: 100781643 100787499 100801553
GSJ: 114393805 114424309
PVU: PHAVU_002G153500g PHAVU_003G213400g
VRA: 106766835
VAR: 108331872
VUN: 114173149 114179429
VUM: 124828916
CCAJ: 109800975 109807162 109808997
APRC: 113850199
MTR: 25493641
TPRA: 123887275
CAM: 101505867
PSAT: 127074093
VVO: 131637179
LJA: 130712017 130741139
ADU: 107488095 107488447
AIP: 107630850 107642975
AHF: 112722171 112749548 112800841 112803997
LANG: 109331715
PCIN: 129321606
QSA: O6P43_024245 O6P43_034184
FVE: 101295808
RCN: 112177267
PPER: 18777949
PMUM: 103337384
PAVI: 110747696
MDM: 103437075 103444758
MSYL: 126619453 126625114
PXB: 103938392 103938400 103952887 103966453 103966464
ZJU: 107405251
MNT: 21405913
CSAV: 115716236
CSV: 101205821
CMO: 103482697
BHJ: 120068335
MCHA: 111026099
CMAX: 111468931 111491279
CMOS: 111430302 111459670
CPEP: 111795697 111808131
RCU: 8265388
MEAN: 126677960
JCU: 105645896
HBR: 110640010 110654801 110673701
MESC: 110609673 110628184
POP: 7465830 7478085
PEU: 105128983 105132185
PALZ: 118028537 118033799
JRE: 108990692 108990870
CILL: 122280452 122289384 122290512
CAVE: 132174749 132181883
QSU: 111989310 112032145
QLO: 115972044
TWL: 119980371 119986524
VVI: 100254814
VRI: 117932414
SLY: 101249670
SPEN: 107028846
SOT: 102601196
SSTN: 125841920
SDUL: 129889963
CANN: 107866265
LBB: 132634986
NTA: 107759475 107780668 107814451
NSY: 104217794 104226056
NTO: 104112154
NAU: 109226774
INI: 109152989 109183545
ITR: 116027296 116027975
SIND: 105157346
OEU: 111376278
EGT: 105958589
SSPL: 121796354 121801326
SMIL: 131026383
SHIS: 125194141
APAN: 127243608
HAN: 110899608 110922166 110930432
ECAD: 122600769
LSV: 111900426 111901165
CCAV: 112499631 112521211 112527665
DCR: 108205323 108209549
CSIN: 114266584 114298300 114306288
RVL: 131331842
AEW: 130752828 130792837
BVG: 104892361
SOE: 110784345
CQI: 110702522 110719436
ATRI: 130800524 130804386
MOF: 131164094
NNU: 104596207 104608336
MING: 122075407 122082415
TSS: 122664708 122670777
PSOM: 113274818 113304323
OSA: 9267465
OBR: 102712502
OGL: 127763220
BDI: 100845999
ATS: 109767781
TDC: 119317431 119322532
TAES: 123128001 123137628 123145096
TUA: 125514107 125514115
LPER: 127306677
LRD: 124687382 124692894
SBI: 8073218
ZMA: 100286359
MFLO: 136463974 136473746 136474561
SITA: 101755451
SVS: 117866881
PVIR: 120656800 120712557
PHAI: 112893336
PDA: 103696614 103696615
EGU: 105054160 105054161
MUS: 103976110 103984640
ZOF: 121991171 122020080 122024069 122041392 122045886
DCT: 110114251
PEQ: 110039075
AOF: 109837996
MSIN: 131248461
NCOL: 116261389
ATR: 18447813
SMO: SELMODRAFT_184467 SELMODRAFT_439393
PPP: 112283741 112283743
CRE: CHLRE_09g387171v5
VCN: VOLCADRAFT_76853
MNG: MNEG_5872
CSL: COCSUDRAFT_28172
CVR: CHLNCDRAFT_132889
APRO: F751_6460
CME: CYME_CMJ314C CYME_CML005C CYME_CMN004C CYME_CMQ005C
GSL: Gasu_16320
NCR: NCU10683
NTE: NEUTE1DRAFT85761(NEUTE1DRAFT_85761)
SMP: 10802451(SMAC4_07414)
PAN: PODANSg2376
PBEL: QC761_504950
PPSD: QC762_504950
PPSP: QC763_504950
PPSA: QC764_504950
TTT: THITE_2049831
MTM: MYCTH_83475
CTHR: CTHT_0047820
MGR: MGG_09238
PPEI: PpBr36_07571
PGRI: PgNI_06190
TMN: UCRPA7_2121
SSCK: SPSK_09656
FGR: FGSG_13414
FPU: FPSE_09569
FPOA: FPOAC1_004302
FVR: FVEG_13508
FOX: FOXG_14692
FFC: NCS54_00969100
FKR: NCS57_00491800
FMU: J7337_011163
TRE: TRIREDRAFT_64836
TRR: M419DRAFT_83036
TATV: 25786453(TrAtP1_006648)
TASP: 36613565(TrAFT101_005885)
PLJ: 28886078(PLICBS_007579) 28892136(PLICBS_004198)
PTKZ: JDV02_009033
VAL: VDBG_07303
VDA: VDAG_06010
CFJ: CFIO01_04617
CLUP: CLUP02_14277
CHIG: CH63R_06220
SAPO: SAPIO_CDS7601
ELA: UCREL1_2336
PFY: PFICI_06797
SSL: SS1G_02529
BFU: BCIN_06g02380
MBE: MBM_09222
PSCO: LY89DRAFT_582723
GLZ: GLAREA_11900
ALUC: AKAW2_40026A
BOR: COCMIDRAFT_31392
ZTR: MYCGRDRAFT_42346
PFJ: MYCFIDRAFT_34055
CBET: CB0940_05034
BCOM: BAUCODRAFT_72815
TML: GSTUM_00002612001
DFA: DFA_11698
ACAN: ACA1_275440
FCY: FRACYDRAFT_191008(RMLC1)
SPAR: SPRG_09826 SPRG_17627
GTT: GUITHDRAFT_89166
TVA: TVAG_2v0535400 TVAG_2v1013510
 » show all
Reference
PMID:17190829
  Authors
Oka T, Nemoto T, Jigami Y
  Title
Functional analysis of Arabidopsis thaliana RHM2/MUM4, a multidomain protein involved in UDP-D-glucose to UDP-L-rhamnose conversion.
  Journal
J Biol Chem 282:5389-403 (2007)
DOI:10.1074/jbc.M610196200
  Sequence
[ath:AT1G63000]
Reference
PMID:20525998
  Authors
Pang CY, Wang H, Pang Y, Xu C, Jiao Y, Qin YM, Western TL, Yu SX, Zhu YX
  Title
Comparative proteomics indicates that biosynthesis of pectic precursors is important for cotton fiber and Arabidopsis root hair elongation.
  Journal
Mol Cell Proteomics 9:2019-33 (2010)
DOI:10.1074/mcp.M110.000349
LinkDB

KEGG   REACTION: R08935
Entry
R08935                      Reaction                               
Name
dTDP-6-deoxy-L-mannose:NADP+ 4-oxidoreductase (3,5-epimerizing)
Definition
dTDP-L-rhamnose + NADP+ <=> dTDP-4-oxo-6-deoxy-D-glucose + NADPH + H+
Equation
C03319 + C00006 <=> C11907 + C00005 + C00080
Comment
two-step reaction (see R06514+R02777)
Reaction class
RC00001  C00005_C00006
RC01014  C03319_C11907
Enzyme
1.1.1.-
Pathway
rn00523  Polyketide sugar unit biosynthesis
rn01110  Biosynthesis of secondary metabolites
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.-
     R08935  dTDP-L-rhamnose + NADP+ <=> dTDP-4-oxo-6-deoxy-D-glucose + NADPH + H+
Orthology
K12451  3,5-epimerase/4-reductase [EC:5.1.3.- 1.1.1.-]
LinkDB

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