KEGG   ORTHOLOGY: K12502
Entry
K12502                      KO                                     
Symbol
VTE3, APG1
Name
MPBQ/MSBQ methyltransferase [EC:2.1.1.295]
Pathway
map00130  Ubiquinone and other terpenoid-quinone biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
map01240  Biosynthesis of cofactors
Module
M00112  Tocopherol/tocotorienol biosynthesis, homogentisate + phytyl/geranylgeranyl-PP => tocopherol/tocotorienol
M00933  Plastoquinone biosynthesis, homogentisate + solanesyl-PP => plastoquinol
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00130 Ubiquinone and other terpenoid-quinone biosynthesis
    K12502  VTE3, APG1; MPBQ/MSBQ methyltransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.295  2-methyl-6-phytyl-1,4-hydroquinone methyltransferase
     K12502  VTE3, APG1; MPBQ/MSBQ methyltransferase
Other DBs
RN: R07501 R10709 R10710
GO: 0051741 0051742
Genes
ATH: AT3G63410(APG1)
ALY: 9312789
CRB: 17887229
CSAT: 104699535 104699536 104748980 104788679 104788680
EUS: EUTSA_v10006087mg
BRP: 103830388
BNA: 106353332 106410579
BOE: 106300824
RSZ: 108818362
THJ: 104801966 104823034
CPAP: 110823242
EGR: 104427271
LJA: Lj5g3v1014830.1(Lj5g3v1014830.1) Lj5g3v1208090.1(Lj5g3v1208090.1)
ADU: 107473483
AIP: 107624907
CSV: 101218864
CMO: 103491265
BHJ: 120077947
MCHA: 111015269
SIND: 105163320
OEU: 111375743
EGT: 105952873
BVG: 104894575
NCOL: 116248949
DOSA: Os07t0179300-00(Os07g0179300) Os12t0615400-01(Os12g0615400)
OBR: 102717119
ZMA: 100284931
SITA: 101777009
SVS: 117847771
PHAI: 112884253
PDA: 103716169
EGU: 105055609
MUS: 103975699
DCT: 110110033
PEQ: 110024315
AOF: 109833025
ATR: 18429566
 » show all
Reference
  Authors
Cheng Z, Sattler S, Maeda H, Sakuragi Y, Bryant DA, DellaPenna D
  Title
Highly divergent methyltransferases catalyze a conserved reaction in tocopherol and plastoquinone synthesis in cyanobacteria and photosynthetic eukaryotes.
  Journal
Plant Cell 15:2343-56 (2003)
DOI:10.1105/tpc.013656
  Sequence
[ath:AT3G63410]
LinkDB

KEGG   ORTHOLOGY: K18534
Entry
K18534                      KO                                     
Symbol
K18534
Name
MPBQ/MSBQ methyltransferase [EC:2.1.1.295]
Pathway
map00130  Ubiquinone and other terpenoid-quinone biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
map01240  Biosynthesis of cofactors
Module
M00112  Tocopherol/tocotorienol biosynthesis, homogentisate + phytyl/geranylgeranyl-PP => tocopherol/tocotorienol
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00130 Ubiquinone and other terpenoid-quinone biosynthesis
    K18534  K18534; MPBQ/MSBQ methyltransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.295  2-methyl-6-phytyl-1,4-hydroquinone methyltransferase
     K18534  K18534; MPBQ/MSBQ methyltransferase
Other DBs
RN: R07501 R10709 R10710
GO: 0051741 0051742
Genes
CRE: CHLRE_14g624350v5
VCN: VOLCADRAFT_105494
MNG: MNEG_2018
CSL: COCSUDRAFT_58884
CVR: CHLNCDRAFT_37067
APRO: F751_0698
OLU: OSTLU_10269 OSTLU_3898
OTA: OT_ostta02g04440 OT_ostta07g04670
BPG: Bathy08g00510 Bathy17g02220
MIS: MICPUN_61308 MICPUN_75700
FCY: FRACYDRAFT_277748(VTE3)
LEZ: GLE_2516
LEM: LEN_2498
CPS: CPS_3306
MHUA: MCHK_3250
MEX: Mext_2411
META: Y590_11650
BVR: BVIR_651
AMI: Amir_0228
SYN: sll0418
SYY: SYNGTS_1914(sll0418)
SYT: SYNGTI_1913(sll0418)
SYS: SYNPCCN_1912(sll0418)
SYQ: SYNPCCP_1912(sll0418)
SYJ: D082_05990(erg6)
SYC: syc0927_c
SYG: sync_0378
CYA: CYA_0166
CYB: CYB_0976
SYNR: KR49_10590
SYND: KR52_00850
SYW: SYNW2141
PMA: Pro_1661
PMM: PMM1505
PMT: PMT_1785
PRC: EW14_1844
PRM: EW15_2010
AMR: AM1_4828
TEL: tll1726
THN: NK55_05270(vte3)
LET: O77CONTIG1_03739(rebM_3)
CYT: cce_2731
TER: Tery_2173
ANA: all2121
AVA: Ava_1078
ANB: ANA_C11801(adpE)
CALH: IJ00_04090
DOU: BMF77_03807(eryG_2)
CEO: ETSB_0305
FMR: Fuma_01242(rebM)
SUS: Acid_6131
CBAL: M667_01525
CBAT: M666_01530
NJA: NSJP_3545
THA: TAM4_1741
THS: TES1_1284
TEU: TEU_11385
MBN: Mboo_1437
MPD: MCP_0823
MEZ: Mtc_1963
RCI: LRC129
 » show all
Reference
  Authors
Shintani DK, Cheng Z, DellaPenna D
  Title
The role of 2-methyl-6-phytylbenzoquinone methyltransferase in determining tocopherol composition in Synechocystis sp. PCC6803.
  Journal
FEBS Lett 511:1-5 (2002)
DOI:10.1016/S0014-5793(01)03223-9
  Sequence
[syn:sll0418]
LinkDB

KEGG   ENZYME: 2.1.1.295
Entry
EC 2.1.1.295                Enzyme                                 
Name
2-methyl-6-phytyl-1,4-hydroquinone methyltransferase;
VTE3 (gene name);
2-methyl-6-solanyl-1,4-hydroquinone methyltransferase;
MPBQ/MSBQ methyltransferase;
MPBQ/MSBQ MT
Class
Transferases;
Transferring one-carbon groups;
Methyltransferases
Sysname
S-adenosyl-L-methionine:2-methyl-6-phytyl-1,4-benzoquinol C-3-methyltransferase
Reaction(IUBMB)
(1) S-adenosyl-L-methionine + 2-methyl-6-phytylbenzene-1,4-diol = S-adenosyl-L-homocysteine + 2,3-dimethyl-6-phytylbenzene-1,4-diol [RN:R07501];
(2) S-adenosyl-L-methionine + 2-methyl-6-all-trans-nonaprenylbenzene-1,4-diol = S-adenosyl-L-homocysteine + plastoquinol [RN:R10709];
(3) S-adenosyl-L-methionine + 6-geranylgeranyl-2-methylbenzene-1,4-diol = S-adenosyl-L-homocysteine + 6-geranylgeranyl-2,3-dimethylbenzene-1,4-diol [RN:R10710]
Reaction(KEGG)
Substrate
S-adenosyl-L-methionine [CPD:C00019];
2-methyl-6-phytylbenzene-1,4-diol [CPD:C15882];
2-methyl-6-all-trans-nonaprenylbenzene-1,4-diol [CPD:C17570];
6-geranylgeranyl-2-methylbenzene-1,4-diol [CPD:C20737]
Product
plastoquinol [CPD:C16695]
Comment
Involved in the biosynthesis of plastoquinol, as well as vitamin E (tocopherols and tocotrienols).
History
EC 2.1.1.295 created 2014
Pathway
ec00130  Ubiquinone and other terpenoid-quinone biosynthesis
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Orthology
K12502  MPBQ/MSBQ methyltransferase
K18534  MPBQ/MSBQ methyltransferase
Genes
ATHAT3G63410(APG1)
ALY9312789
CRB17887229
CSAT104699535 104699536 104748980 104788679 104788680
EUSEUTSA_v10006087mg
BRP103830388
BNA106353332 106410579
BOE106300824
RSZ108818362
THJ104801966 104823034
CPAP110823242
CIT102614553 102630396
CICCICLE_v10005361mg CICLE_v10021032mg
PVY116131110 116145854 116146149
MINC123211534 123212063
TCC18603086 18613261
GRA105777662 105790679 105796688 105803144
GHI107897057 107902204 107914985 107915302 107924420 107924562 107927797 107941613
GAB108470117 108474174 108475431 108484494
DZI111305232 111307356 111314269
EGR104427271
GMX100783986 100788766 100806615
GSJ114371939 114377441 114389734
PVUPHAVU_007G175500g PHAVU_007G279000g
VRA106772053 106772119
VAR108324031 108326079
VUN114190003 114192009
CCAJ109798185 109813953
APRC113871244 113873393 113873781
MTRMTR_1g071110 MTR_1g076570
CAM101490902 101491654
LJALj5g3v1014830.1(Lj5g3v1014830.1) Lj5g3v1208090.1(Lj5g3v1208090.1)
ADU107473483
AIP107624907
AHF112726944 112737364
LANG109336117 109346662
FVE101303502 101310277
RCN112168757 112196927 112200119
PPER18767488 18790101
PMUM103323966 103334183
PAVI110760969 110763422
PDUL117638272 117638826
MDM103413350 103419087 103424079 103425704
PXB103929764 103960081 103964755
ZJU107413125 107425921
MNT21395748 21396522
CSV101218864
CMO103491265
BHJ120077947
MCHA111015269
CMAX111466918 111491019
CMOS111437409 111463939
CPEP111795869 111811588
RCU8276696 8280209
JCU105632060 105649922
HBR110631738 110636214 110645645
MESC110602226 110611451 110615165
POP7473437 7476869 7480667
PEU105126799 105127667 105131376
PALZ118049320 118056626 118061641
JRE108997758 109005098 109018791
QSU111999076 112034239
QLO115971346 115994415
TWL119991203 120007114
VVI100240861 100266496
VRI117914735 117918894
SLY101255662 101267644
SPEN107014330 107031218
SOT102592709 102604412
CANN107863813 107868474
NTA107760985 107773365 107793127 107814278
NSY104210164 104242982
NTO104092670 104096486
NAU109209900 109219112
INI109173882 109176188
ITR116002492 116003478
SIND105163320
OEU111375743
EGT105952873
SSPL121792938 121802014
HAN110865372 110937001
ECAD122581366 122590943
LSV111882798 111882799 111890210 111897498
CCAV112506818 112512534
DCR108206732 108223925 108223932
CSIN114266558 114273086 114292680 114304669 114317890
BVG104894575
SOE110777066 110781171 110783632
CQI110728964 110734434
NNU104612757 104613253
MING122059318 122069172 122071571 122073267 122083763 122092451
TSS122644257 122671792 122671811 122671822 122671833
PSOM113318712 113342468 113347188 113350010
NCOL116248949
OSA107277102 4352791
DOSAOs07t0179300-00(Os07g0179300) Os12t0615400-01(Os12g0615400)
OBR102717119
BDI100831760 100837610
ATS109753840 109759333 109759692
TDC119287160 119294532 119298951 119307247 119321410
TAES100415847 123087377 123090555 123095599 123102141 123119319 123127840 123137605 123144936
SBI8071468 8071470
ZMA100284931
SITA101777009
SVS117847771
PVIR120666941 120684537 120684538 120685323 120686264 120700139
PHAI112884253
PDA103716169
EGU105055609
MUS103975699
DCT110110033
PEQ110024315
AOF109833025
ATR18429566
SMOSELMODRAFT_130062 SELMODRAFT_230434
PPP112280584 112281506
CRECHLRE_14g624350v5 CHLRE_14g625450v5
VCNVOLCADRAFT_105494 VOLCADRAFT_81811
MNGMNEG_2018
CSLCOCSUDRAFT_12124 COCSUDRAFT_58884
CVRCHLNCDRAFT_140353 CHLNCDRAFT_37067
APROF751_0698
OLUOSTLU_10269 OSTLU_3898
OTAOT_ostta02g04440 OT_ostta07g04670
BPGBathy08g00510 Bathy17g02220
MISMICPUN_61308 MICPUN_75700
MPPMICPUCDRAFT_34256 MICPUCDRAFT_49396
CMECYME_CMD011C
GSLGasu_48400
CCPCHC_T00009101001
PTIPHATR_33530
FCYFRACYDRAFT_277748(VTE3)
TPSTHAPSDRAFT_37444
AAFAURANDRAFT_12910
EHXEMIHUDRAFT_221641 EMIHUDRAFT_98396
GTTGUITHDRAFT_65997 GUITHDRAFT_91786
LEZGLE_2516
LEMLEN_2498
PBMCL52_05635
CPSCPS_3306
CELLCBR65_12380
TTITHITH_12505
PTXABW99_05420
VAPVapar_5778
DSADesal_0296
DMLDmul_17470
MLNA9174_18090
MHUAMCHK_3250
MJREB229_18355
BRQCIT40_06200
MEAMex_1p2414
MEXMext_2411
MZAB2G69_19680
METAY590_11650
DEQXM25_18770
YTIFNA67_00420
BVRBVIR_651
LABPFJ695_03590
ROMEI983_14700
SCARDWB96_02690
RALRumal_0207
NTPCRH09_08470
STSIA4E84_00975
SCOECP976_04955
NGVCDO52_13170
APRECNX65_01070
AMIAmir_0228
SESPBN6_02660 BN6_22810
EUZDVS28_a1298
SYNsll0418
SYZMYO_119320
SYYSYNGTS_1914(sll0418)
SYTSYNGTI_1913(sll0418)
SYSSYNPCCN_1912(sll0418)
SYQSYNPCCP_1912(sll0418)
SYJD082_05990(erg6)
SYOC7I86_09985
SYCsyc0927_c
SYUM744_13870
SYFSynpcc7942_0596
SYDSyncc9605_0317
SYESyncc9902_2025
SYGsync_0378
SYRSynRCC307_2173
SYXSynWH7803_0376
SYPSYNPCC7002_A2739
CYACYA_0166
CYBCYB_0976
SYNKKR100_02995
SYNRKR49_10590
SYNDKR52_00850
SYHSyncc8109_0322
SYNWSynWH8103_02461
SYVAWQ23_13640 AWQ23_15555
SYLAWQ21_13595
SYNCCB0101_10165
DSLDacsa_3100
SYWSYNW2141
CGCCyagr_1868
CYICBM981_1908
PMAPro_1661
PMMPMM1505
PMTPMT_1785
PMNPMN2A_1071
PMIPMT9312_1597
PMBA9601_17081
PMCP9515_16851
PMFP9303_23681
PMGP9301_16961
PMHP9215_17731
PMJP9211_16281
PMENATL1_19461
PRCEW14_1844
PRMEW15_2010
CMPCha6605_4756
AMRAM1_4828
TVNNIES2134_116440
SLWBRW62_05420
TELtll1726
THNNK55_05270(vte3)
THECFFX45_07145
LEPLepto7376_1190
LENLEP3755_04620
LETO77CONTIG1_03739(rebM_3)
LBOLBWT_48160
LSKJ5X98_11220 J5X98_25630
HHGXM38_051350
PSEUPse7367_2884
THEUHPC62_08375
GLPGlo7428_4337
GENGM3709_2257 GM3709_617
GEEGM3708_3417 GM3708_802
CHONNIES4102_10550
MARMAE_31670 MAE_59960
MPKVL20_1779 VL20_6363
MIQB5D77_02930
MVZmyaer102_07060 myaer102_32120
CANCyan10605_1399
CSNCyast_0466
CYLAA637_00340 AA637_13830
HAOPCC7418_0287
ENNFRE64_14920
CYUUCYN_02180
CYTcce_2731
CWACwatDRAFT_4775
CYCPCC7424_3824
TERTery_2173
ARPNIES39_A07610
OXYHCG48_08780
LFSHFV01_00315
MICMic7113_5784
OACOscil6304_5103
ONIOsc7112_6030
MPROBJP34_30195
PHORJWS08_11250
ANAall2121
NONNOS3756_36660
NFLCOO91_01274 COO91_04730
NOECLI64_15980
NEDHUN01_01475 HUN01_02990 HUN01_03115
AVAAva_1078
ANBANA_C11801(adpE)
ANNEH233_21115
CALOCal7507_0565 Cal7507_4157
CALTCal6303_4397
CALHIJ00_04090
RIVRiv7116_2940
FISFIS3754_43390
NSPBMF81_01182
DOUBMF77_03807(eryG_2)
DFSHGD76_24065
TOQHCG51_02875
NCNBZZ01_23585
PLPPle7327_1307
SCSSta7437_4216
STANSTA3757_03790
CEOETSB_0305
CERRGRSB_0258
FMRFuma_01242(rebM)
SUSAcid_6131
ASXCDL62_02910
PCMAY601_1224
CBALM667_01525
CBATM666_01530
LACICW733_04680
SPONHME9304_00844
WIJBWZ20_11920
SYISB49_00195
OLLCW732_07315
FEKC1H87_16935
AQAD1815_12110
MGELG5B37_12465
FLGLV716_11585
NIONITINOP_0343
NJANSJP_3545
NKFNkreftii_001819
TBATERMP_01250
THATAM4_1741
THSTES1_1284
TEUTEU_11385
TTDA3L14_08820
PPACPAP_07330 PAP_07335
MBGBN140_2314
MBNMboo_1437
MFOMetfor_1715
MPDMCP_0823
MEZMtc_1963
RCILRC129
HJEHacjB3_15446 HacjB3_19178
HSNDV733_09600
HLMDV707_17885
HRUHalru_0646
TARTALC_00982
 » show all
Reference
1  [PMID:11821038]
  Authors
Shintani DK, Cheng Z, DellaPenna D
  Title
The role of 2-methyl-6-phytylbenzoquinone methyltransferase in determining tocopherol composition in Synechocystis sp. PCC6803.
  Journal
FEBS Lett 511:1-5 (2002)
DOI:10.1016/S0014-5793(01)03223-9
  Sequence
[syn:sll0418]
Reference
2  [PMID:14508009]
  Authors
Cheng Z, Sattler S, Maeda H, Sakuragi Y, Bryant DA, DellaPenna D
  Title
Highly divergent methyltransferases catalyze a conserved reaction in tocopherol and plastoquinone synthesis in cyanobacteria and photosynthetic eukaryotes.
  Journal
Plant Cell 15:2343-56 (2003)
DOI:10.1105/tpc.013656
  Sequence
Reference
3  [PMID:14630966]
  Authors
Van Eenennaam AL, Lincoln K, Durrett TP, Valentin HE, Shewmaker CK, Thorne GM, Jiang J, Baszis SR, Levering CK, Aasen ED, Hao M, Stein JC, Norris SR, Last RL
  Title
Engineering vitamin E content: from Arabidopsis mutant to soy oil.
  Journal
Plant Cell 15:3007-19 (2003)
DOI:10.1105/tpc.015875
  Sequence
[ath:AT3G63410] [ana:all2121]
Other DBs
ExplorEnz - The Enzyme Database: 2.1.1.295
IUBMB Enzyme Nomenclature: 2.1.1.295
ExPASy - ENZYME nomenclature database: 2.1.1.295
BRENDA, the Enzyme Database: 2.1.1.295
LinkDB

KEGG   REACTION: R10709
Entry
R10709                      Reaction                               
Name
S-adenosyl-L-methionine:2-methyl-6-solanyl-1,4-benzoquinol C3-methyltransferase
Definition
S-Adenosyl-L-methionine + 2-Methyl-6-solanyl-1,4-benzoquinol <=> S-Adenosyl-L-homocysteine + Plastoquinol-9
Equation
Reaction class
RC00003  C00019_C00021
RC01662  C16695_C17570
Enzyme
Pathway
rn00130  Ubiquinone and other terpenoid-quinone biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01240  Biosynthesis of cofactors
Module
M00933  Plastoquinone biosynthesis, homogentisate + solanesyl-PP => plastoquinol
Orthology
K12502  MPBQ/MSBQ methyltransferase [EC:2.1.1.295]
K18534  MPBQ/MSBQ methyltransferase [EC:2.1.1.295]
Other DBs
RHEA: 38002
LinkDB

DBGET integrated database retrieval system