KEGG ORTHOLOGY: K12630

ORTHOLOGY: K12630

Entry

K12630            Tight     KO

Symbol

pur4

Name

puromycin biosynthesis protein Pur4 [EC:2.-.-.-]

Pathway

map00998

Biosynthesis of various antibiotics

map01100

Metabolic pathways

map01110

Biosynthesis of secondary metabolites

Module

M00889

Puromycin biosynthesis, ATP => puromycin

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00998 Biosynthesis of various antibiotics
    K12630  pur4; puromycin biosynthesis protein Pur4
Enzymes [BR:ko01000]
2. Transferases
  2.-
   2.-.-
    2.-.-.-
     K12630  pur4; puromycin biosynthesis protein Pur4

Other DBs

RN:

R05670

Genes

SALW:

CP975_29290

AG:	CAA63162(pur4)

Reference

PMID:8576156

Authors

Tercero JA, Espinosa JC, Lacalle RA, Jimenez A.

Title

The biosynthetic pathway of the aminonucleoside antibiotic puromycin, as deduced from the molecular analysis of the pur cluster of Streptomyces alboniger.

Journal

J Biol Chem 271:1579-90 (1996)
DOI:10.1074/jbc.271.3.1579

Sequence

[ag:CAA63162]

LinkDB

REACTION: R05670

Entry

R05670                      Reaction

Definition

3'-Keto-3'-deoxy-AMP <=> 3'-Amino-3'-deoxy-AMP

Equation

C07025 <=> C07026

Comment

Pur4, the presumptive aminotransferase, pyridoxal phosphate/ L-
glutamate-dependent enzyme
Ref.1. The Journal of Biological chemistry; vol.271, No.3, Jan 19,
pp.1579-1590, 1996

Reaction class

RC00781

C07025_C07026

Enzyme

2.-.-.-

Pathway

rn00998

Biosynthesis of various antibiotics

rn01100

Metabolic pathways

rn01110

Biosynthesis of secondary metabolites