ORTHOLOGY: K12631
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Entry
K12631 Tight KO
Symbol
pur6
Name
puromycin biosynthesis protein Pur6
Pathway
map00998
Biosynthesis of various antibiotics
map01100
Metabolic pathways
map01110
Biosynthesis of secondary metabolites
Module
M00889
Puromycin biosynthesis, ATP => puromycin
Reaction
R05671
Brite
KEGG Orthology (KO) [BR:
ko00001
]
09100 Metabolism
09110 Biosynthesis of other secondary metabolites
00998 Biosynthesis of various antibiotics
K12631 pur6; puromycin biosynthesis protein Pur6
BRITE hierarchy
Genes
SALW:
CP975_29285
Taxonomy
UniProt
Reference
PMID:
15556612
Authors
Angel Rubio M, Barrado P, Carlos Espinosa J, Jimenez A, Fernandez Lobato M
Title
The pur6 gene of the puromycin biosynthetic gene cluster from Streptomyces alboniger encodes a tyrosinyl-aminonucleoside synthetase.
Journal
FEBS Lett 577:371-5 (2004)
DOI:
10.1016/j.febslet.2004.09.087
Sequence
[salw:
CP975_29285
]
LinkDB
All DBs
REACTION: R05671
Help
Entry
R05671 Reaction
Definition
3'-Amino-3'-deoxy-AMP + L-Tyrosine <=> N6,N6,O-Tridemethylpuromycin-5'-phosphate
Equation
C07026
+
C00082
<=>
C07027
Comment
incomplete reaction
Pur6
Reaction class
RC00141
C00082_C07027
RC00166
C07026_C07027
Pathway
rn00998
Biosynthesis of various antibiotics
rn01100
Metabolic pathways
rn01110
Biosynthesis of secondary metabolites
Module
M00889
Puromycin biosynthesis, ATP => puromycin
Orthology
K12631
puromycin biosynthesis protein Pur6
LinkDB
All DBs
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integrated database retrieval system