KEGG   ORTHOLOGY: K12632
Entry
K12632            Tight     KO                                     
Symbol
pac
Name
puromycin N-acetyltransferase [EC:2.3.-.-]
Pathway
map00998  Biosynthesis of various antibiotics
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00889  Puromycin biosynthesis, ATP => puromycin
Reaction
R05672  
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00998 Biosynthesis of various antibiotics
    K12632  pac; puromycin N-acetyltransferase
Genes
SALW: CP975_29305
Reference
PMID:2676728
  Authors
Lacalle RA, Pulido D, Vara J, Zalacain M, Jimenez A
  Title
Molecular analysis of the pac gene encoding a puromycin N-acetyl transferase from Streptomyces alboniger.
  Journal
Gene 79:375-80 (1989)
DOI:10.1016/0378-1119(89)90220-5
  Sequence
[salw:CP975_29305]
LinkDB

KEGG   REACTION: R05672
Entry
R05672                      Reaction                               
Definition
N6,N6,O-Tridemethylpuromycin-5'-phosphate + Acetyl-CoA <=> N-Acetyl-N6,N6,O-tridemethylpuromycin-5'-phosphate + CoA
Equation
C07027 + C00024 <=> C07028 + C00010
Comment
Pac, puromycin N-acetyltransferase
Ref.1. The Journal of Biological chemistry; vol.271, No.3, Jan 19,
pp.1579-1590, 1996
Reaction class
RC00004  C00010_C00024
RC00064  C07027_C07028
Enzyme
2.3.-.-
Pathway
rn00998  Biosynthesis of various antibiotics
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00889  Puromycin biosynthesis, ATP => puromycin
Brite
Enzymatic reactions [BR:br08201]
 2. Transferase reactions
  2.3  Acyltransferases
   2.3.-  Acyltransferases
    2.3.-.-
     R05672  N6,N6,O-Tridemethylpuromycin-5'-phosphate + Acetyl-CoA <=> N-Acetyl-N6,N6,O-tridemethylpuromycin-5'-phosphate + CoA
Orthology
K12632  puromycin N-acetyltransferase [EC:2.3.-.-]
LinkDB

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