KEGG   ORTHOLOGY: K12636
Entry
K12636            Tight     KO                                     
Symbol
napH
Name
N-acetylpuromycin N-acetylhydrolase
Pathway
map00998  Biosynthesis of various antibiotics
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00889  Puromycin biosynthesis, ATP => puromycin
Reaction
R05677  
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00998 Biosynthesis of various antibiotics
    K12636  napH; N-acetylpuromycin N-acetylhydrolase
Genes
SALW: CP975_29270
Reference
PMID:8576156
  Authors
Tercero JA, Espinosa JC, Lacalle RA, Jimenez A.
  Title
The biosynthetic pathway of the aminonucleoside antibiotic puromycin, as deduced from the molecular analysis of the pur cluster of Streptomyces alboniger.
  Journal
J Biol Chem 271:1579-90 (1996)
DOI:10.1074/jbc.271.3.1579
  Sequence
[salw:CP975_29270]
LinkDB

KEGG   REACTION: R05677
Entry
R05677                      Reaction                               
Definition
N-Acetylpuromycin + H2O <=> Puromycin + Acetate
Equation
C07032 + C00001 <=> C01610 + C00033
Comment
NapH, N-acetylpuromycin N-acetylhydrolase
Ref.1. The Journal of Biological chemistry; vol.271, No.3, Jan 19,
pp.1579-1590, 1996
Reaction class
RC00064  C01610_C07032
RC00300  C00033_C07032
Pathway
rn00998  Biosynthesis of various antibiotics
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00889  Puromycin biosynthesis, ATP => puromycin
Orthology
K12636  N-acetylpuromycin N-acetylhydrolase
LinkDB

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