KEGG   ORTHOLOGY: K12658
Entry
K12658                      KO                                     
Symbol
lhpA
Name
4-hydroxyproline epimerase [EC:5.1.1.8]
Pathway
map00470  D-Amino acid metabolism
map01100  Metabolic pathways
Module
M00948  Hydroxyproline degradation, trans-4-hydroxy-L-proline => 2-oxoglutarate
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00470 D-Amino acid metabolism
    K12658  lhpA; 4-hydroxyproline epimerase
Enzymes [BR:ko01000]
 5. Isomerases
  5.1  Racemases and epimerases
   5.1.1  Acting on amino acids and derivatives
    5.1.1.8  4-hydroxyproline epimerase
     K12658  lhpA; 4-hydroxyproline epimerase
Other DBs
RN: R03296
COG: COG3938
GO: 0047580
Genes
EAS: Entas_0541
KPY: KPNIH31_04610
KPI: D364_24425
KVA: Kvar_4458
KPE: KPK_4825
KPK: A593_14025
KVD: KR75_11475
KVQ: SP68_18110
KQU: AVR78_07830
EAE: EAE_10385
EAR: CCG31917
CRO: ROD_25441
SMAR: SM39_1308
SPE: Spro_1840
SPLY: Q5A_009110
SMAF: D781_1750
SERF: L085_19525
EAM: EAMY_2591
EAY: EAM_2486
EPY: EpC_10350
PLU: plu2243
PAY: PAU_02148
PSI: S70_20130
PSX: DR96_2925
XCC: XCC2415
XCB: XC_1697
XCP: XCR_2716
XCV: XCV2748
XAX: XACM_2531
XAC: XAC2550
XOM: XOO2983(XOO2983)
XOO: XOO3141
XOP: PXO_01435
XOR: XOC_1905
XAL: XALC_1966
XPH: XppCFBP6546_19660(XppCFBP6546P_19660)
LEZ: GLE_4612
LEM: LEN_0609
VPA: VP1330
VPB: VPBB_1254
VAG: N646_0364
PAE: PA1268
PAEV: N297_1308
PAEI: N296_1308
PAEP: PA1S_19570
PAEM: U769_19415
PAEL: T223_20660
PAEG: AI22_14395
PAEC: M802_1305
PAEO: M801_1307
PPU: PP_1258(prpA)
PPF: Pput_1285
PPT: PPS_3964
PPI: YSA_07696
PPX: T1E_3148
PPUH: B479_19705
PPUT: L483_25125
PPUN: PP4_11970
PPUD: DW66_4403
PMON: X969_19355
PMOT: X970_18990
PFL: PFL_1412
PPRO: PPC_1466(prdF)
PFS: PFLU_3324
PFB: VO64_0473
PMAN: OU5_0407
PFW: PF1751_v1c27910(prpA)
PEN: PSEEN4050
PSTT: CH92_01075
PSES: PSCI_2441(prdF) PSCI_5066
PSEM: TO66_07015
PSOS: POS17_1435(prdF)
PANR: A7J50_3071
PSET: THL1_1574
PSIL: PMA3_19310
PDW: BV82_1498
PSEP: C4K39_1456
PALI: A3K91_1189
ACB: A1S_1325
ABY: ABAYE2385
ABN: AB57_1509
ABX: ABK1_1774
ABAD: ABD1_13350
ABAZ: P795_10755
ABAU: IX87_03820
SAZ: Sama_1530
SLO: Shew_2363
SSE: Ssed_1761
SPL: Spea_1703
SHL: Shal_2556
SWD: Swoo_2823
SWP: swp_1983
SVO: SVI_1709
SPSW: Sps_03406
CPS: CPS_1450
PSEO: OM33_13465
PSPO: PSPO_a2280
PSAZ: PA25_17410
FBL: Fbal_2401
SAGA: M5M_03815
HCH: HCH_03167
CSA: Csal_2705
HEL: HELO_1555(lhpA)
HAM: HALO1344
OCE: GU3_02575
SALN: SALB1_1998
CVI: CV_2826
PSE: NH8B_1448
AMAH: DLM_1554
BMA: BMAA1419
BMAE: DM78_4009
BMAI: DM57_08765
BMAF: DM51_5063
BMAZ: BM44_4891
BMAB: BM45_3793
BPS: BPSS0332
BPSE: BDL_3564
BPSM: BBQ_5867
BPSU: BBN_3728
BPSD: BBX_5402
BPK: BBK_5544
BPSH: DR55_5015
BPSA: BBU_5785
BPSO: X996_4784
BUT: X994_4284
BTQ: BTQ_5347
BTJ: BTJ_3999
BTZ: BTL_4823
BTD: BTI_4399
BTV: BTHA_5407
BTHE: BTN_4473
BTHM: BTRA_4739
BTHA: DR62_4587
BTHL: BG87_4804
BOK: DM82_4401
BOC: BG90_3675
BSAV: WS86_20485
BVE: AK36_4218
BCN: Bcen_4226
BCJ: BCAM1267
BCEN: DM39_3735 DM39_4868(prpA)
BCEW: DM40_4178
BCEO: I35_5115
BAM: Bamb_3550
BMJ: BMULJ_03255(prdF) BMULJ_04062(prdF)
BMK: DM80_3612 DM80_4477(prpA)
BMUL: NP80_4167
BCT: GEM_4477
BCED: DM42_3826
BDL: AK34_4213
BCON: NL30_06270
BUB: BW23_4939
BLAT: WK25_23240
BTEI: WS51_04015
BSEM: WJ12_26185
BPSL: WS57_07700
BMEC: WJ16_24810
BSTG: WT74_25125
BGU: KS03_5541
BGO: BM43_4180
BUK: MYA_4525
BUL: BW21_3932
BXB: DR64_6195 DR64_6722(prpA)
BPH: Bphy_4667
BFN: OI25_6626
CABA: SBC2_59320
BPT: Bpet1262
VEI: Veis_1044
CARE: LT85_0637
ALK: ALEK_0477
MXA: MXAN_6199
MLO: mll3979
MHUA: MCHK_5287
SME: SM_b20268
SMER: DU99_32030
SMD: Smed_3863
ATU: Atu3953
ARA: Arad_8151
AVI: Avi_7251
RLE: pRL120535
RLG: Rleg_4841
RHT: NT26_0739
KAI: K32_04720
BME: BMEI0257
BMEL: DK63_1176(prpA)
BMEE: DK62_1771(prpA)
BMF: BAB1_1800
BABO: DK55_1743(prpA)
BABR: DO74_145(prpA)
BABT: DK49_1500(prpA)
BABB: DK48_376(prpA)
BABU: DK53_1726(prpA)
BABS: DK51_1816(prpA)
BABC: DO78_1647(prpA)
BMS: BR1792
BSZ: DK67_555(prpA)
BOV: BOV_1726
BCAR: DK60_1784(prpA)
BCAS: DA85_08590
BMR: BMI_I1809
BPP: BPI_I1849
BPV: DK65_1721(prpA)
OAN: Oant_1111
OAH: DR92_662(prpA)
OCH: CES85_2178(prpA)
BOS: BSY19_3324(prpA)
SNO: Snov_0157
MET: M446_3463
MIND: mvi_42330
PHL: KKY_179
MMED: Mame_00325
PSF: PSE_4633(pA45-A)
SIL: SPOA0266
KVU: EIO_3242
PGD: Gal_02995
SMAZ: LH19_25010
SPHU: SPPYR_0563
STAX: MC45_12595
SPHI: TS85_02900
SSAN: NX02_19045
SECH: B18_18080
SSY: SLG_18120
BLAS: BSY18_2025
RRU: Rru_A2065
RRF: F11_10620
TMO: TMO_b0094
TXI: TH3_13285
HAU: Haur_2499
DFC: DFI_14735
RBA: RB2078
PSL: Psta_1257
RUL: UC8_44200
AHEL: Q31a_27940
PLM: Plim_2713
FTJ: FTUN_4738
ACA: ACP_3275
GBA: J421_4877
RMR: Rmar_0498
CPI: Cpin_5572
FLN: FLA_4334
MUC: MuYL_0981
SLI: Slin_1478
DFE: Dfer_4273
LBY: Lbys_1776
FAE: FAES_4419
GFL: GRFL_0580
ZPR: ZPR_1383
MARM: YQ22_13930
CBAL: M667_17520
CBAT: M666_17525
DDO: I597_0359
MLT: VC82_2609
WIN: WPG_1843
TMAR: MARIT_0674
MARF: CJ739_3133
EAO: BD94_2186
CHZ: CHSO_2635
 » show all
Reference
  Authors
Goytia M, Chamond N, Cosson A, Coatnoan N, Hermant D, Berneman A, Minoprio P
  Title
Molecular and structural discrimination of proline racemase and hydroxyproline-2-epimerase from nosocomial and bacterial pathogens.
  Journal
PLoS One 2:e885 (2007)
DOI:10.1371/journal.pone.0000885
  Sequence
[pae:PA1268]
LinkDB

KEGG   ENZYME: 5.1.1.8
Entry
EC 5.1.1.8                  Enzyme                                 
Name
4-hydroxyproline epimerase;
hydroxyproline epimerase;
hydroxyproline 2-epimerase;
L-hydroxyproline epimerase
Class
Isomerases;
Racemases and epimerases;
Acting on amino acids and derivatives
Sysname
4-hydroxyproline 2-epimerase
Reaction(IUBMB)
trans-4-hydroxy-L-proline = cis-4-hydroxy-D-proline [RN:R03296]
Reaction(KEGG)
R03296
Substrate
trans-4-hydroxy-L-proline [CPD:C01157]
Product
cis-4-hydroxy-D-proline [CPD:C03440]
Comment
Also interconverts trans-4-hydroxy-D-proline and cis-4-hydroxy-L-proline.
History
EC 5.1.1.8 created 1965, modified 1983
Pathway
ec00470  D-Amino acid metabolism
ec01100  Metabolic pathways
Orthology
K12658  4-hydroxyproline epimerase
Genes
EASEntas_0541
KPYKPNIH31_04610
KPID364_24425
KVAKvar_4458
KPEKPK_4825
KPKA593_14025
KVDKR75_11475
KVQSP68_18110
KQUAVR78_07830
EAEEAE_10385
EARCCG31917
KQVB8P98_24170
KARLGL98_21770
RORRORB6_15495
RPLNB1209_23450
RAODSD31_22205
RTGNCTC13098_06406
CROROD_25441
CYOCD187_21055
CPOTFOB25_08110
PGELG71_25430
ESCEntcl_3792
KLEAO703_02955
BUFD8682_03000
IZHFEM41_12810
EBUCUC76_12015
SMARSM39_1308
SMACSMDB11_1090
SMWSMWW4_v1c17880
SPESpro_1840
SRRSerAS9_1787
SRLSOD_c16660
SRYM621_09230
SPLYQ5A_009110
SRSSerAS12_1787
SRASerAS13_1788
SMAFD781_1750
SLQM495_08565
SERFL085_19525
SERSSERRSCBI_08610
SFWWN53_20945
SFGAV650_16755
SERMCLM71_08480
SFJSAMEA4384070_1864
SSURATE40_005745
SURIJ0X03_14765
SRHZFO014_01460
SFOZ042_01690
EAMEAMY_2591
EAYEAM_2486
EPYEpC_10350
EPREPYR_01097
ERJEJP617_00540
TCIA7K98_02935
PLUplu2243
PLUMA4R40_11240
PAYPAU_02148
PTTVY86_20750
PLUICE143_11480
PSIS70_20130
PSXDR96_2925
PSTABGK56_02120
PRGRB151_020620
PALACO695_15355
PHEINCTC12003_02202
PRQCYG50_06835
PRJNCTC6933_01765
PVCG3341_11190
PFQQQ39_16065
XCCXCC2415
XCBXC_1697
XCAxcc-b100_1751
XCPXCR_2716
XCVXCV2748
XAXXACM_2531
XACXAC2550
XCIXCAW_02230
XCTJ151_02731
XCJJ158_02718
XCUJ159_02716
XCNJ169_02728
XCWJ162_02720
XCRJ163_02715
XCMJ164_02717
XCFJ172_02722
XFUXFF4834R_chr25730
XAOXAC29_12990
XOMXOO2983(XOO2983)
XOOXOO3141
XOPPXO_01435
XOYAZ54_08210
XORXOC_1905
XOZBE73_08920
XALXALC_1966
XSASB85_05490
XTNFD63_07125
XFRBER92_06200
XVEBJD12_03760
XPEBJD13_03730
XHRXJ27_06625
XGABI317_10040
XPHXppCFBP6546_19660(XppCFBP6546P_19660)
XVAC7V42_09425
XANAC801_09430
XARXB05_07640
XHYFZ025_02410
XCZEBN15_09570
XTHG4Q83_06270
XEUXSP_002533
XHDLMG31886_17380
PJPLAG73_15525
LABLA76x_0733
LAQGLA29479_2942
LCPLC55x_4766
LGULG3211_4557
LEZGLE_4612
LEMLEN_0609
LYJFKV23_07085
TBVH9L17_07610
XBCELE36_05365
FAUFraau_1365
RGLCS053_00950 CS053_07865
DJICH75_13715
DJAHY57_09850
DTLH8F01_16395
XBAC7S18_21505
VPAVP1330
VPBVPBB_1254
VPKM636_15160
VPFM634_08560
VPHVPUCM_1893
VAGN646_0364
VEXVEA_003673
VDBAL552_14855
VHRAL538_01805
VNAPN96_19565
VOWA9237_01125
VCYIX92_23565
VCTJV59_15985
VTUIX91_16995
VEUIXK98_02520
VAFD1115_07890
VNLD3H41_06585
VZIG5S32_08795
PGHFH974_23630
PAEPA1268
PAEVN297_1308
PAEIN296_1308
PAUPA14_47840
PAPPSPA7_4122
PAGPLES_40441
PAFPAM18_3761
PNCNCGM2_2151 NCGM2_3706
PAEBNCGM1900_1307 NCGM1900_3822
PDKPADK2_19305
PSGG655_18825
PRPM062_06905
PAEPPA1S_19570
PAERPA1R_gp4875
PAEMU769_19415
PAELT223_20660
PAESSCV20265_4145
PAEUBN889_01350
PAEGAI22_14395
PAECM802_1305
PAEOM801_1307
PFUWKF707C_24900
PALCA0T30_01455
PCQPcP3B5_24830 PcP3B5_28750 PcP3B5_34570
PMUIG4G71_28360
PPUPP_1258(prpA)
PPFPput_1285
PPGPputGB1_4133
PPTPPS_3964
PPBPPUBIRD1_1294
PPIYSA_07696
PPXT1E_3148
PPUHB479_19705
PPUTL483_25125
PPUNPP4_11970
PPUDDW66_4403
PFVPsefu_4418
PMONX969_19355
PMOTX970_18990
PMOSO165_002025
PPJRK21_00523
PORAPT59_21770
PMOLCLJ08_19375
PFLPFL_1412
PPRCPFLCHA0_c14490
PPROPPC_1466(prdF)
PFEPSF113_3730
PFNHZ99_05395
PFOPfl01_2308
PFSPFLU_3324
PFCPflA506_2818
PPZH045_08140
PFBVO64_0473
PMANOU5_0407
PTVAA957_28680
PCGAXG94_01265
PVRPverR02_16500
PAZOAYR47_23115
POIBOP93_11745
PRXHRH33_14455
PFWPF1751_v1c27910(prpA)
PFFPFLUOLIPICF722350
PFXA7318_12865
PENPSEEN4050
PSTTCH92_01075
PLULFOB45_09595
PBAPSEBR_a3196 PSEBR_a3615
PBCCD58_14065
PPUUPputUW4_03027
PDRH681_03770
PSVPVLB_18500
PSKU771_17650
PCHEY04_06345
PCZPCL1606_46990
PCPJM49_23290
PFZAV641_19725
PALKPSAKL28_28610
PRHLT40_08335
PPVNJ69_17255
PSESPSCI_2441(prdF) PSCI_5066
PSEMTO66_07015
PSECCCOS191_3996
PSOSPOS17_1435(prdF)
PKRAYO71_13765
PFKPFAS1_24915
PANRA7J50_3071
PPSLBJP27_14530
PSETTHL1_1574
PSILPMA3_19310
PYMAK972_3853
PKEDLD99_12295
PUMHGP31_13940
POJPtoMrB4_26290
PGGFX982_00223
PPSHG5J76_10820
PGYAWU82_15525
PLALFXN65_03380
PVKEPZ47_14010
PEZHWQ56_12105 HWQ56_17335
PBZGN234_05075
PKHJLK41_24620
PATAJWU58_16460
PDWBV82_1498
PZEHU754_012940
PMOEHV782_017155
PSEPC4K39_1456
PVWHU752_014635 HU752_021515
PTRTHU722_0015800
PXAKSS93_22835
PSAMHU731_002330
PTZHU718_017575
PQIKH389_15835
PSHHHU773_016140
PXNHU772_018175
PHVHU739_006370
PANHHU763_018040
PASGKSS96_15605
PFAKKSS94_16245 KSS94_20280
PMUYKSS95_21000
PMAMKSS90_06640
PAZEKSS91_13970
PALVKSS97_15440
PORYEJA05_20970
PTKEXN22_15820
PTWTUM18999_27450
PZAHU749_017205
PIEHU724_011675
PTAENCTC10697_01420
PAGRE2H98_16805
PCRPcryo_1219
PSOPSYCG_06385
PURAOC03_00875
PALIA3K91_1189
PSPGAK823_06700
PSYGAK825_06765
PSYPE5677_07470
ACBA1S_1325
ABYABAYE2385
ABCACICU_01326
ABNAB57_1509
ABBABBFA_02178
ABXABK1_1774
ABZABZJ_01488
ABRABTJ_02381
ABDABTW07_1497
ABADABD1_13350
ABJBJAB07104_01490
ABABBJAB0715_01509
ABAJBJAB0868_01440
ABAZP795_10755
ABKLX00_06560
ABAUIX87_03820
ABWBL01_18100
ABALABLAC_21510
ACCBDGL_000672
ANORR32_11430
ACDAOLE_12105
MOIMOVS_02180
MCUNNCTC10297_01218
SAZSama_1530
SLOShew_2363
SSESsed_1761
SPLSpea_1703
SHLShal_2556
SWDSwoo_2823
SWPswp_1983
SVOSVI_1709
SPSWSps_03406
SMAVCFF01_07490
SALGBS332_20155
SBKSHEWBE_3284
SKHSTH12_01173
SLITJQC75_07520
SDKKHX94_06920
SPSHFM037_11255
SEURFM038_25745
SCYPJYB88_10685
SSEMJYB85_10915
CPSCPS_1450
COMCMT41_05460
LSDEMK97_07585
PTNPTRA_b0294
PSEOOM33_13465
PPHEPP2015_1749
PRRAT705_00790
PLZS4054249_08025
PALNB0W48_16325
PPISB1L02_07715
PSPOPSPO_a2280
PTUPTUN_a1048
PSENPNC201_08055
PDJD0907_20875
PVBJ5X90_13155
PSAZPA25_17410
FBLFbal_2401
SAGAM5M_03815
MAGAMag101_08150
SPIUSPICUR_01000
SROSBBH56_00070
WOCBA177_11560
HCHHCH_03167
HAHEENC22_16380
CSACsal_2705
HELHELO_1555(lhpA)
HAMHALO1344
HHUAR456_14415
HALKCUU95_10925
HOLHORIV_50650
HAAA5892_04255
MMWMmwyl1_0052
MMEMarme_0039
MPCMar181_0042
MPRIMP3633_0053
MARDIBG28_00270
MFOIJSY38_09535
MPRFJ8N69_08225
OCEGU3_02575
OPFCBP31_07865
SALNSALB1_1998
NZOSAMEA4504057_0104
NCINCTC10296_00382
NWDH3L96_05200
NDULVJ88_11320
CVICV_2826
CVCBKX93_22585
CHROCXB49_07680
CHRIDK842_16535
CHRBDK843_22060
CRZD1345_06000
CHRMFYK34_04575
CHAECH06BL_13030
PSENH8B_1448
AMAHDLM_1554
AQSDKK66_00820
VOGLCH97_02140
CBWRR42_s3255
BMABMAA1419
BMLBMA10229_2193
BMNBMA10247_A0881
BMAEDM78_4009
BMAIDM57_08765
BMAFDM51_5063
BMAZBM44_4891
BMABBM45_3793
BPSBPSS0332
BPMBURPS1710b_A1887
BPLBURPS1106A_A0473
BPDBURPS668_A0570
BPSEBDL_3564
BPSMBBQ_5867
BPSUBBN_3728
BPSDBBX_5402
BPZBP1026B_II0362
BPQBPC006_II0450
BPKBBK_5544
BPSHDR55_5015
BPSABBU_5785
BPSOX996_4784
BUTX994_4284
BTEBTH_II2067
BTQBTQ_5347
BTJBTJ_3999
BTZBTL_4823
BTDBTI_4399
BTVBTHA_5407
BTHEBTN_4473
BTHMBTRA_4739
BTHADR62_4587
BTHLBG87_4804
BOKDM82_4401
BOCBG90_3675
BUUWS70_19135
BSAVWS86_20485
BVIBcep1808_4702
BVEAK36_4218
BURBcep18194_B1894
BCNBcen_4226
BCHBcen2424_4140
BCMBcenmc03_3379
BCJBCAM1267
BCENDM39_3735 DM39_4868(prpA)
BCEWDM40_4178
BCEOI35_5115
BAMBamb_3550
BACBamMC406_3228 BamMC406_4031
BMJBMULJ_03255(prdF) BMULJ_04062(prdF)
BMUBmul_4447 Bmul_5265
BMKDM80_3612 DM80_4477(prpA)
BMULNP80_4167
BCTGEM_4477
BCEDDM42_3826
BCEPAPZ15_18350
BDLAK34_4213
BPYRABD05_29815
BCONNL30_06270
BUBBW23_4939
BDFWI26_19420
BLATWK25_23240
BTEIWS51_04015
BSEMWJ12_26185
BPSLWS57_07700
BMECWJ16_24810
BSTGWT74_25125
BSTLBBJ41_19320
BANNJFN94_23525
BGLbglu_2g03790
BGUKS03_5541
BUGBC1001_4119
BGFBC1003_5297
BGDbgla_2g05500
BGOBM43_4180
BYIBYI23_B007710 BYI23_C005580 BYI23_D012930
BUKMYA_4525
BUEBRPE67_BCDS11660 BRPE67_CCDS05880 BRPE67_DCDS01610
BULBW21_3932
BUQAC233_29010
BGPBGL_2c04710
BPLAbpln_2g05260
BUDAQ610_21240
BUMAXG89_17965
BUIAX768_27745
BURKDM992_19525
BXEBxe_B0874 Bxe_B1419
BXBDR64_6195 DR64_6722(prpA)
BPHBphy_4667
BGEBC1002_4388
BPXBUPH_00701
BPYBphyt_4560
BUZAYM40_30990
BFNOI25_6626
BCAIK788_0004660
PSPWBJG93_24055
PARABTO02_32195
PARBCJU94_22135 CJU94_24675
PHSC2L64_22165
PTERC2L65_25805
PGPCUJ91_27205
PCJCUJ87_17800 CUJ87_32180
PTSCUJ90_19470
PCAFDSC91_000916 DSC91_002492
PMEGFNZ07_01550
PTROG5S35_34705
PGISI6I06_25200
PACPFAZ97_21345
PACSFAZ98_17490
PEWKZJ38_35030
PDIOPDMSB3_1683.1 PDMSB3_2311.1
PTXABW99_01800 ABW99_02275
PLGNCTC10937_03084
CABASBC2_59320
BUOBRPE64_BCDS05530 BRPE64_DCDS01060
CARIFNU76_09175
BPTBpet1262
BBROBAU06_08035
BFZBAU07_18110
BOHAKI39_07850
ASWCVS48_09900 CVS48_27745
ACHBDVB37_06545
AKATKWG_22305
CDNBN940_17211
RHYRD110_12565
RHGEXZ61_00245
ACKC380_11045
ARADKI609_12915
VEIVeis_1044
VAPVapar_5220
VPEVarpa_5949
VPDVAPA_1c54290
VBOCKY39_32695
VAMC4F17_19450
CODOLAD35_11560
HTNKI616_09025
SIMPC6571_14975
KIAG8A07_04590 G8A07_14900
CARELT85_0637
CPRACPter91_0669
MNRACZ75_08900
MASSCR152_26255
MASZC9I28_07885
MASYDPH57_14175
MPLIE1742_00620
DUGHH213_06385
UPVEJN92_05405
UPIEJG51_008910
RDPRD2015_597
PKTAT984_00145
XYKGT347_16785
UPLDSM104440_02164
ALKALEK_0477
ALPLPB137_02125
AANAAANAER_1613
MXAMXAN_6199
MSDMYSTI_00790
MFBMFUL124B02_04405
MLOmll3979
MLNA9174_06120
MCIMesci_1233
MOPMesop_1262
MAMMesau_01273
MAMOA6B35_02220 A6B35_24420
MESWA9K65_006350
MESMEJ066_05310
MESPC1M53_22685
MHUAMCHK_5287
MJREB229_06315
MERDEB233_06265
MESRFGU64_13235 FGU64_15400
MESOBSQ44_00390
HOEIMCC20628_00289
AAKAA2016_1328
AMIHCO731_01295
PHTBLM14_00670
NIYFQ775_16230
NKIKW403_09925
SMESM_b20268
SMKSinme_3905
SMQSinmeB_4402
SMXSM11_pD1343
SMIBN406_06398
SMEGC770_GR4pD1329
SMELSM2011_b20268
SMERDU99_32030
SMDSmed_3863
SFHSFHH103_05091
SAMESAMCFNEI73_Ch3106
EADOV14_a1337
EAHFA04_26870
ESJSJ05684_b60020
EAKEKH55_4111
EMXFKV68_00700
ATUAtu3953
ARAArad_8151
AVIAvi_7251
AROB0909_18130
RETRHE_PF00391
RECRHECIAT_PC0000572
RELREMIM1_PF00517
REPIE4803_PC00383
REIIE4771_PD00401
RLEpRL120535
RLTRleg2_5285
RLGRleg_4841
RHLLPU83_1797
RHXAMK02_PD00331
RJGCCGE525_27865
RHRCKA34_30240
RADCO657_27215
RIIFFM53_034330
RBQJ2J99_31045
RLNJ0663_29945
RRGJ3P73_26675
RLSHB780_11495
RHTNT26_0739
RFVRFYW14_00932
KAIK32_04720
BMEBMEI0257
BMELDK63_1176(prpA)
BMIBMEA_A1842
BMZBM28_A1785
BMGBM590_A1783
BMWBMNI_I1714
BMEEDK62_1771(prpA)
BMFBAB1_1800
BMBBruAb1_1773
BMCBAbS19_I16820
BAABAA13334_I01121
BABODK55_1743(prpA)
BABRDO74_145(prpA)
BABTDK49_1500(prpA)
BABBDK48_376(prpA)
BABUDK53_1726(prpA)
BABSDK51_1816(prpA)
BABCDO78_1647(prpA)
BMSBR1792
BSIBS1330_I1786
BSFBSS2_I1734
BSUIBSSP1_II1232
BSUPBSPT1_II1224
BSUVBSPT2_II1226
BSUCBSSP2_II1234
BMTBSUIS_B1268
BSZDK67_555(prpA)
BSVBSVBI22_A1788
BSWIY71_08780
BSGIY72_08545 IY72_14185
BOVBOV_1726
BCSBCAN_A1830
BSKBCA52141_I2334
BOLBCOUA_I1792
BCARDK60_1784(prpA)
BCASDA85_08590
BMRBMI_I1809
BPPBPI_I1849
BPVDK65_1721(prpA)
BCETV910_100248
BCEEV568_100275
BVLBF3285c1_1076
BRUBFS01_08555
BRJBKD03_12885
OINIAR37_00600
BIOBR141012304_10922
OANOant_1111
OAHDR92_662(prpA)
OPSA8A54_09110
OCHCES85_2178(prpA)
OCRHGK82_10480
OCLGTN27_10710
PSCQKHQ08_15300
BOPAXW83_09435
BOSBSY19_3324(prpA)
BVVBHK69_23970
BOIBLM15_24185
BOFFQV39_08040
SNOSnov_0157
STARG3545_19665 G3545_23210
LNEFZC33_04680
ANCGBB76_15710
APRAG3A50_09700 G3A50_11700
METM446_3463
MAQUMaq22A_c07705
MTEADK419_13965
MINDmvi_42330
MOCBB934_08130
MIVC4E04_19945
MICOGDR74_01540
RHJHZY79_15860
CHELAL346_01215
CDQBOQ54_12070
PHLKKY_179
DEQXM25_16220
MMYRMXMO3_02559
YTIFNA67_19620
MEYTM49_22125
MAADAZF01_19440
MMEDMame_00325
MLUTJET14_20315
AUAM673_01850
AALAIGS74_14695
AALMLUX29_16610
NOHG5V57_03860
PSFPSE_4633(pA45-A)
PPHRAPZ00_24925
LAPACP90_03830
LABRCHH27_16915
LABPFJ695_09480
LABTFIU93_09465
LAGGB0E33_15390
SIWGH266_09810
PHRC6569_13005
PSTGE8M01_06270
LIZLGH83_15005
CHQAQ619_05625
CAUFCSW63_04785
CAULKCG34_22445
BNEDA69_11450
BDMEQG53_10130
BVYNCTC9239_01934
AEXAstex_3396
TSVDSM104635_00274
SILSPOA0266
SITTM1040_3199
RUAD1823_21550
RUTFIU92_20905
KVLKVU_PB0058
KVUEIO_3242
PGAPGA1_c05120
PGLPGA2_c04680
PGDGal_02995
PHPPhaeoP97_02845
PPICPhaeoP14_00434
PHQD1820_15670
LMDMETH_17505
CEHCEW89_00400
YPACCEW88_21665
SULDB5M07_16965
SINLDSM14862_03937
RMMROSMUCSMR3_03768
ROKRAK1035_2608
HATRC74_17900
RHPLPB142_00850 LPB142_07535
RBLB6K69_11120
PDEPden_3467 Pden_4859
PAMIJCM7686_pAMI5p193
PCONB0A89_11810
PARUCYR75_12390
PARSDRW48_02015
PKDF8A10_10075
PPANESD82_09080
PSANHGN31_03535
RMBK529_019745
DAAAKL17_3798
THWBMG03_19990
GFUKM031_16580
TAWEI545_04770
HMLHmaOT1_15365
PSEBEOK75_17425
LITFPZ52_12365
PAEDG5B38_02485
PALWPSAL_037660
PPAFI8N54_03040
FAPGR316_11090
FAQG5B39_15240
MMRMmar10_0298
CBOTATE48_11840
NOVTQ38_021135 TQ38_024025
NDRHT578_09470
SMAGAN936_21745
SMAZLH19_25010
SPHUSPPYR_0563
STAXMC45_12595
SPHITS85_02900
SSANNX02_19045
SPANAWL63_14825
SPLMBXU08_00210
SPLKAV944_04730
SPHCCVN68_06000
SPHFDM480_08830
SPAUDRN02_009275
SECHB18_18080
SPAPH3Z74_00360
SSYSLG_18120
SYAA6768_06520
SPYGYGS_C2P1167
BLASBSY18_2025
BFWB5J99_01685
SPHSETR14_21130
GTIFXF46_11445
GFAMKW11_12565
KSCCD178_02869
APERA0U91_00455
RGIRGI145_21200
ROSCTJ15_00810
RMUCFOB66_01880
LCKHN018_00945
KHAIFJ82_08360
AZZDEW08_20000
NAOY958_11900
NCBC0V82_25890
RRURru_A2065
RRFF11_10620
TMOTMO_b0094
HTQFRZ44_41980
HADHFRZ61_40190
TXITH3_13285
THACCSC3H3_22470
TIIDY252_15965
ECOGFIV45_12850
PARHI5S86_22275
HAUHaur_2499
DDRDeide_1p00350
DSWQR90_12520
DFCDFI_14735
DEINDAAJ005_15415
DPHEHF33_18105
FGIOP10G_0839
NPYNPRO_13680
OBGVerru16b_02508
OLEK0B96_03380
LUOHHL09_21830
LAMBKBB96_12490
RBARB2078
PSLPsta_1257
PIRVN12_26860
RULUC8_44200
RMLFF011L_16000
MFFMFFC18_23990
ROLCA51_31050
AHELQ31a_27940
LCREPla8534_64190
AAGGETAA8_57540
BVOPan97_34700
RLCK227x_30710
PNDPla175_21570
PLMPlim_2713
PEHSpb1_34750
PBSPlabr_3242
PLSVT03_05355
PLHVT85_05725
FMRFuma_03369
GIMF1728_30300
GPNPan110_30150
MRIMal4_39040
GESVT84_21635
GOGC1280_06035
GMSSOIL9_37420
TIMGMBLW1_33840
LRSPX52LOC_04328
FTJFTUN_4738
ULIETAA1_51450
TSPHKIH39_21025
PBORBSF38_05464
AGVOJF2_36830
HBSIPV69_06400
ACAACP_3275
ACMAciX9_4246
GMAAciX8_4767
TALBFTW19_05745
PFERIRI77_07280
SCORJ3U87_18355
GBAJ421_4877
MCOSGM418_07485
RMRRmar_0498
RMGRhom172_0496
CPICpin_5572
CHITFW415_20285
CHIHGWR21_08420
COYHF329_03640
NKONiako_2575
ARBA9P82_07220
ARKD6B99_09140
AGIFSB73_05605
ARACE0W69_010865
FLNFLA_4334
PSEGD3H65_12355
FLSGLV81_05245
LACSH4075_16565
FLCKJS93_15625
HHYHalhy_1216
PCMAY601_2802
PSTYBFS30_03900
PGSCPT03_11945
PEKFFJ24_006420
PROEH9L23_06905
SHGSph21_0988
SPHNBV902_10365
SMIZ4412673_01389
SPSCE2P86_12480
SPDRG6053_08350
STHANCTC11429_00325
SMUII6J00_25915
SSIYJVX97_22475
MUPA0256_02465
MUCMuYL_0981
MGOTMgSA37_00737
MUHHYN43_006300
MGINFRZ54_11710
MGKFSB76_23320
MRUBDEO27_002515
MGOSDIU38_017740
MMABHQ865_15910
MDJLLH06_16625
AGDFRZ59_02090
OLIFKG96_01940
SBXCA265_05710
BBDBelba_0715
EVIEchvi_3951
ESTDN752_03310
ECHIFKX85_18545
ALMAO498_04355
MDAIPZ59_07220
SLISlin_1478
SRDSD10_14035
SPIRCWM47_19135
SPIKEXU85_07460
SPIBG8759_28555
SRHOHH216_04090
DFEDfer_4273
DSNHWI92_16325
LBYLbys_1776
RSIRunsl_2578
RUNDR864_13055
RUPDTQ70_28305
EOLEmtol_3473
FAEFAES_4419
FIBA6C57_21500
ALSDJ013_13160
CHKD4L85_30360
GFLGRFL_0580
FJGBB050_03533
FCOFCOL_10755
FCRHYN56_19515
FCVAWN65_09595
FOEJJC03_08370
RBIRB2501_00826
ZPRZPR_1383
FBCFB2170_10616
MARMYQ22_13930
MARTBTR34_13915
MARBCJ263_10985
MAREEJ994_07470
CAOCelal_4236
CLYCelly_3234
CLHIX49_16340
CBALM667_17520
CBATM666_17525
KDIKrodi_0882
DOKMED134_07841
DDOI597_0359
DODDCS32_07590
LACICW733_10530
ZGAZOBELLIA_4012
MRSMurru_0609
MLTVC82_2609
MUTGVT53_13245
MAQILDL77_04760
SPONHME9304_02946
PTQP700755_002875
POLABXQ17_12230
POACW731_06415
PHALH9I45_00365
PLITK8354_12175
WINWPG_1843
SYISB49_02915
TDIAUW17_01985
TENLPB136_08465
TJETJEJU_3627
TMARMARIT_0674
TMPF9Y86_10285
FORFORMB_08970
AALGAREALGSMS7_04191
KOSKORDIASMS9_03300
KANIMCC3317_06500
MARFCJ739_3133
AQBD1818_16685
AQAD1815_20065
AQDD1816_19490
EMARD1013_13440
MUREQY75_05000
AFLAFHG64_15165
GAAHX109_05330
CAGGHYG79_15880
LPALLDL79_09575
SINHLS482_06095
ASAGFGM00_06455
FLGLV716_17550
ZSPMQE36_11965
FBUUJ101_02218
FBEFF125_18750
EAOBD94_2186
EMNM876_08005
EENBBD30_15980
ELBVO54_00507
EGOBBD34_00055
EGMAYC65_07305
ELZFCS00_00050
CHZCHSO_2635
CIOCEQ15_07005
CHRYCEY12_04140
CPIPCJF12_03820
CNKEG343_01720
CBENEG339_18310
CGLENCTC11432_00789
CLACEG342_18090
 » show all
Reference
1  [PMID:14189888]
  Authors
ADAMS E, NORTON IL.
  Title
PURIFICATION AND PROPERTIES OF INDUCIBLE HYDROXYPROLINE 2-EPIMERASE FROM PSEUDOMONAS.
  Journal
J Biol Chem 239:1525-35 (1964)
Other DBs
ExplorEnz - The Enzyme Database: 5.1.1.8
IUBMB Enzyme Nomenclature: 5.1.1.8
ExPASy - ENZYME nomenclature database: 5.1.1.8
BRENDA, the Enzyme Database: 5.1.1.8
CAS: 9024-23-1
LinkDB

KEGG   REACTION: R03296
Entry
R03296                      Reaction                               
Name
trans-4-Hydroxy-L-proline 2-epimerase
Definition
Hydroxyproline <=> cis-4-Hydroxy-D-proline
Equation
Reaction class
RC00479  C01157_C03440
Enzyme
Pathway
rn00470  D-Amino acid metabolism
rn01100  Metabolic pathways
Module
M00948  Hydroxyproline degradation, trans-4-hydroxy-L-proline => 2-oxoglutarate
Orthology
K12658  4-hydroxyproline epimerase [EC:5.1.1.8]
Other DBs
RHEA: 21155
LinkDB

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