KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
09110 Biosynthesis of other secondary metabolites
00960 Tropane, piperidine and pyridine alkaloid biosynthesis
K12692 H6H; hyoscyamine (6S)-dioxygenase / 6beta-hydroxyhyoscyamine epoxidase
Enzymes [BR:ko01000]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.11 With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
1.14.11.11 hyoscyamine (6S)-dioxygenase
K12692 H6H; hyoscyamine (6S)-dioxygenase / 6beta-hydroxyhyoscyamine epoxidase
1.14.20 With 2-oxoglutarate as one donor, and the other dehydrogenated
1.14.20.13 6beta-hydroxyhyoscyamine epoxidase
K12692 H6H; hyoscyamine (6S)-dioxygenase / 6beta-hydroxyhyoscyamine epoxidase
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With 2-oxoglutarate as one donor, and the other dehydrogenated
Enzymatic reactions [BR:br08201]
1. Oxidoreductase reactions
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.20 With 2-oxoglutarate as one donor, and the other dehydrogenated
1.14.20.13
R03737 (6S)-Hydroxyhyoscyamine + 2-Oxoglutarate + Oxygen <=> Scopolamine + Succinate + CO2 + H2O