ORTHOLOGY: K12701
Help
Entry
K12701 KO
Symbol
novH
Name
novobiocin biosynthesis protein NovH
Pathway
map00401
Novobiocin biosynthesis
map01100
Metabolic pathways
map01110
Biosynthesis of secondary metabolites
Reaction
R06751
Brite
KEGG Orthology (KO) [BR:
ko00001
]
09100 Metabolism
09110 Biosynthesis of other secondary metabolites
00401 Novobiocin biosynthesis
K12701 novH; novobiocin biosynthesis protein NovH
BRITE hierarchy
Genes
NHU:
H0264_05755
STAA:
LDH80_10560
STPB:
QR97_37430
SCAJ:
O1G22_18785
NGV:
CDO52_02180
AG:
AAF67501
(novH)
AAG29780
(couH)
AAN65224
(cloH)
Taxonomy
UniProt
Reference
PMID:
10770754
Authors
Steffensky M, Muhlenweg A, Wang ZX, Li SM, Heide L
Title
Identification of the novobiocin biosynthetic gene cluster of Streptomyces spheroides NCIB 11891.
Journal
Antimicrob Agents Chemother 44:1214-22 (2000)
DOI:
10.1128/AAC.44.5.1214-1222.2000
Sequence
[ag:
AAF67501
]
LinkDB
All DBs
REACTION: R06751
Help
Entry
R06751 Reaction
Definition
L-Tyrosine + Peptidyl-carrier protein + ATP <=> L-Tyrosyl-[pcp] + AMP + Diphosphate
Equation
C00082
+
C21097
+
C00002
<=>
C12461
+
C00020
+
C00013
Comment
peptide synthetase, NovH CloH CouH
Peptidyl-carrier protein is pcp domain of the enzyme itself [KO:
K12701
].
Reaction class
RC00039
C12461_C21097
RC00137
C00082_C12461
Pathway
rn00401
Novobiocin biosynthesis
rn01100
Metabolic pathways
rn01110
Biosynthesis of secondary metabolites
Orthology
K12701
novobiocin biosynthesis protein NovH
LinkDB
All DBs
DBGET
integrated database retrieval system