KEGG   ORTHOLOGY: K12710
Entry
K12710                      KO                                     
Symbol
novU
Name
C-methyltransferase [EC:2.1.1.-]
Pathway
map00523  Polyketide sugar unit biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
map01250  Biosynthesis of nucleotide sugars
Module
M00795  dTDP-beta-L-noviose biosynthesis
Reaction
R11020  S-adenosyl-L-methionine:dTDP-4-oxo-6-deoxy-D-allose 5-C-methyltransferase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00523 Polyketide sugar unit biosynthesis
    K12710  novU; C-methyltransferase
Genes
SGB: WQO_33785
SPHW: NFX46_24950
SNIG: HEK616_47340
NGV: CDO52_02250
NGN: LCN96_24345
ACTN: L083_3187
AG: AAF67514(novU) AAG29803(couU) AAN65243(cloU)
Reference
  Authors
Steffensky M, Muhlenweg A, Wang ZX, Li SM, Heide L
  Title
Identification of the novobiocin biosynthetic gene cluster of Streptomyces spheroides NCIB 11891.
  Journal
Antimicrob Agents Chemother 44:1214-22 (2000)
DOI:10.1128/AAC.44.5.1214-1222.2000
  Sequence
Reference
  Authors
Tello M, Jakimowicz P, Errey JC, Freel Meyers CL, Walsh CT, Buttner MJ, Lawson DM, Field RA
  Title
Characterisation of Streptomyces spheroides NovW and revision of its functional assignment to a dTDP-6-deoxy-D-xylo-4-hexulose 3-epimerase.
  Journal
Chem Commun (Camb) 1079-81 (2006)
DOI:10.1039/b515763c
LinkDB

KEGG   REACTION: R11020
Entry
R11020                      Reaction                               
Name
S-adenosyl-L-methionine:dTDP-4-oxo-6-deoxy-D-allose 5-C-methyltransferase
Definition
S-Adenosyl-L-methionine + dTDP-4-oxo-6-deoxy-D-allose <=> S-Adenosyl-L-homocysteine + dTDP-4-oxo-5-C-methyl-L-rhamnose
Equation
Reaction class
RC00003  C00019_C00021
RC03148  C11460_C11926
Enzyme
2.1.1.-
Pathway
rn00523  Polyketide sugar unit biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01250  Biosynthesis of nucleotide sugars
Module
M00795  dTDP-beta-L-noviose biosynthesis
Brite
Enzymatic reactions [BR:br08201]
 2. Transferase reactions
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.-
     R11020  S-Adenosyl-L-methionine + dTDP-4-oxo-6-deoxy-D-allose <=> S-Adenosyl-L-homocysteine + dTDP-4-oxo-5-C-methyl-L-rhamnose
Orthology
K12710  C-methyltransferase [EC:2.1.1.-]
LinkDB

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