KEGG   ORTHOLOGY: K12913
Entry
K12913            Tight     KO                                     
Symbol
phsC
Name
phosphinothricin tripeptide synthetase PhsC
Pathway
map00440  Phosphonate and phosphinate metabolism
map01110  Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00440 Phosphonate and phosphinate metabolism
    K12913  phsC; phosphinothricin tripeptide synthetase PhsC
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins
    K12913  phsC; phosphinothricin tripeptide synthetase PhsC
Polyketide biosynthesis proteins [BR:ko01008]
 Nonribosomal peptide synthetase (NRPS)
  Linear NRPS
   Bialaphos synthetase
    K12913  phsC; phosphinothricin tripeptide synthetase PhsC
Other DBs
RN: R08872
Genes
AG: CAJ14039(phsC)
Reference
  Authors
Lee JH, Evans BS, Li G, Kelleher NL, van der Donk WA
  Title
In vitro characterization of a heterologously expressed nonribosomal Peptide synthetase involved in phosphinothricin tripeptide biosynthesis.
  Journal
Biochemistry 48:5054-6 (2009)
DOI:10.1021/bi900164d
LinkDB

KEGG   REACTION: R08872
Entry
R08872                      Reaction                               
Name
N-acetyldemethylphosphinothricin:L-alanine:L-alanine ligase (AMP-forming)
Definition
N-Acetyldemethylphosphinothricin + 2 L-Alanine + 3 ATP + H2O <=> N-Acetyldemethylphosphinothricin tripeptide + 3 AMP + 3 Diphosphate
Equation
C17949 + 2 C00041 + 3 C00002 + C00001 <=> C17950 + 3 C00020 + 3 C00013
Comment
nonribosomal peptide synthetase
Reaction class
RC00064  C00041_C17950
RC00141  C17949_C17950
RC01227  C00041_C17950
Pathway
rn00440  Phosphonate and phosphinate metabolism
rn01110  Biosynthesis of secondary metabolites
Orthology
K12911  phosphinothricin tripeptide synthetase PhsA
K12912  phosphinothricin tripeptide synthetase phsB [EC:6.2.1.67]
K12913  phosphinothricin tripeptide synthetase PhsC
LinkDB

DBGET integrated database retrieval system