KEGG   ORTHOLOGY: K13019
Entry
K13019                      KO                                     
Symbol
wbpI, wlbD
Name
UDP-GlcNAc3NAcA epimerase [EC:5.1.3.23]
Pathway
map00520  Amino sugar and nucleotide sugar metabolism
map00541  O-Antigen nucleotide sugar biosynthesis
map01100  Metabolic pathways
map01250  Biosynthesis of nucleotide sugars
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00520 Amino sugar and nucleotide sugar metabolism
    K13019  wbpI, wlbD; UDP-GlcNAc3NAcA epimerase
  09107 Glycan biosynthesis and metabolism
   00541 O-Antigen nucleotide sugar biosynthesis
    K13019  wbpI, wlbD; UDP-GlcNAc3NAcA epimerase
Enzymes [BR:ko01000]
 5. Isomerases
  5.1  Racemases and epimerases
   5.1.3  Acting on carbohydrates and derivatives
    5.1.3.23  UDP-2,3-diacetamido-2,3-dideoxyglucuronic acid 2-epimerase
     K13019  wbpI, wlbD; UDP-GlcNAc3NAcA epimerase
Other DBs
RN: R09600
COG: COG0381
Genes
PLU: plu4804(wblH)
PLUM: A4R40_23895
PAY: PAU_04319(wblH)
PTT: VY86_07555
PAKH: B0X70_24585
PLUI: CE143_24625
AVT: NCTC3438_01782(mnaA)
PAE: PA3148(wbpI)
PAEV: N297_3260
PAEI: N296_3260
PAEC: M802_3258
PAEO: M801_3125
PSES: PSCI_2869
PANH: HU763_007170(wecB)
MARJ: MARI_04700(wbpI)
SSE: Ssed_2967
SVM: KDH10_000090(wecB)
PVB: J5X90_03260(wecB)
AAUS: EP12_05170
CBD: CBUD_0907
CBG: CbuG_1159(wecB)
CBC: CbuK_0710(wecB)
LSS: NCTC12082_00069(wecB)
THIM: KFB96_04765(wecB)
TNI: TVNIR_0699(wecB_[C])
HTT: HZS52_20515(wecB)
MFOI: JSY38_06670(wecB)
SUTR: L0B52_03945(wecB)
VMS: LVJ82_06325(wecB)
LHK: LHK_02802
PPNO: DA70_17285
LMIR: NCTC12852_00313(mnaA_2)
BPE: BP0090(bplD)
BPC: BPTD_0086(bplD)
BPER: BN118_0159(wlbD)
BPET: B1917_0093(bplD)
BPEU: Q425_2030(bplD)
BPAR: BN117_0150(wlbD)
BPA: BPP0152(bplD)
BBH: BN112_3259(wlbD)
BBR: BB0152(bplD)
BBM: BN115_0141(wlbD)
BBX: BBS798_0151(bplD)
BPT: Bpet4819(wlbD)
BHO: D560_1331
BHM: D558_1320
BHZ: ACR54_00107(wbpI)
BTRM: SAMEA390648701339(wlbD)
TEA: KUI_0418
TEG: KUK_0136
OUE: I6G29_01430(wecB)
AAV: Aave_0953
DLA: I6G47_27680(wecB)
TTW: LCC91_03265(wecB)
HMS: HMU06640
HCL: NCTC13205_01069(mnaA)
HSH: NHP194022_04670(wbpI)
WSU: WS2189(WBPI)
CBLA: CBLAS_0721
ABU: Abu_0692
PACO: AACT_0957
HBV: ABIV_0881
GLO: Glov_1505
GPL: M1B72_07930(wecB)
DSF: UWK_02413
DOL: Dole_1828
PMOB: HG718_00065(wecB)
RBS: RHODOSMS8_00383(wbpI)
SZO: K8M09_00485(wecB)
BQB: J4P68_0006725(wecB)
SPOT: G6548_17145(wecB)
SPHU: SPPYR_1658(wbpI)
PHAO: HF685_11090(wecB)
MAI: MICA_1024
MAN: A11S_979
CSUA: IM538_21360(wecB)
CFIR: NAF01_22635(wecB)
CSOA: LIS82_24390(wecB)
GKA: GK3162
GGH: GHH_c32370(mnaA)
GZA: IC807_11880(wecB)
PTB: DER53_03255(wecB)
AAMY: GFC30_485
PSYO: PB01_04645
MARY: LAU42_03945(wecB)
ATHE: K3F53_17210(wecB)
CHEB: HH215_20205(wecB)
KPUL: GXN76_15365(wecB)
KEB: GXN75_16725(wecB)
CBO: CBO3100
CBA: CLB_3129
CBH: CLC_3002
CBY: CLM_3506
CBL: CLK_2494
CBK: CLL_A3182
CBB: CLD_1440
CBI: CLJ_B3366
CBT: CLH_2927
CBF: CLI_3159
CBM: CBF_3148
CBE: Cbei_4627
CBZ: Cbs_4627
CBEI: LF65_05170
CKL: CKL_3166
CKR: CKR_2804
CAH: CAETHG_1305(wecB)
CSQ: CSCA_4791
CTYK: CTK_C08720
CGAS: J1C67_09865(wecB)
HHW: NCTC503_01993(wecB)
CCEL: CCDG5_0710
CAML: H6X83_09690(wecB)
CFEM: HCR03_17330(wecB)
PTH: PTH_0384(WecB) PTH_1103(WecB)
AACX: DEACI_0260
ELM: ELI_2561
SAY: TPY_3671(wecB)
TTE: TTE0661(WecB2)
CWO: Cwoe_5917
PARN: NBH00_24920(wecB)
SBAE: DSM104329_04159(wbpI_1) DSM104329_05200(wbpI_2)
ELE: Elen_0637
HHG: XM38_017570(wbpI)
OXY: HCG48_01150(wecB)
GLJ: GKIL_0481(wecB)
CALH: IJ00_16800
DFO: Dform_01826(wecB)
RCA: Rcas_0784
THUG: KNN16_05605(wecB)
DRD: LMT64_11870(wecB)
TTH: TT_C0285
PUV: PUV_00130
AHEL: Q31a_45020(wbpI_1)
LCRE: Pla8534_69410(wbpI)
TPED: TPE_0207
FCI: I6I83_02405(wecB)
TLI: Tlie_1813
BUN: Bun01g_30650(wbpI)
BSTE: K6V31_02460(wecB)
PGOL: K6V26_13515(wecB)
TFO: BFO_2566
BVIR: I6J59_01690(wecB) I6J59_14280(wecB)
BACC: BRDCF_p1451(wecB)
DORI: FH5T_09075
CPI: Cpin_4757
SPIB: G8759_15505(wecB)
FKA: KM029_13900(wecB)
ZGA: ZOBELLIA_1741(wecB)
SPON: HME9304_01541(wbpI)
CRM: K6119_19005(wecB)
CHYD: H4K34_02735(wecB)
PTAN: CRYO30217_01158(wbpI_2)
SHYR: LA303_04925(wecB)
MRO: MROS_2673
CPRV: CYPRO_2717
CACI: CLOAM1218(wecB)
TMW: THMA_0626
TMQ: THMB_0626
TMX: THMC_0626
TRQ: TRQ2_0326
TLE: Tlet_1207
TME: Tmel_0366
THER: Y592_05005
FNO: Fnod_0568
FIA: NA23_00760(wecB)
MARN: LN42_06735
KOL: Kole_1631
ASAC: ATHSA_0040
DTU: Dtur_0574
ALAM: RT761_00505(wbpI)
MVO: Mvol_0232
PFI: PFC_03140
TSI: TSIB_2024
THM: CL1_0830
THS: TES1_1887
THEI: K1720_03030(wecB)
MBAR: MSBR2_0018
MMAC: MSMAC_1844
METM: MSMTP_0932
MBU: Mbur_2022
MTP: Mthe_1235
MCJ: MCON_2577(wecB)
MHU: Mhun_0382
MRTJ: KHC33_15080(wecB)
MBG: BN140_0822(wecB1) BN140_2091(wecB3)
RCI: RCIX1930(wecB)
HALX: M0R89_17775(wecB)
HAXZ: M0R88_18115(wecB)
HMU: Hmuk_2022
HALL: LC1Hm_1346(wecB2)
HPEL: HZS54_05795(wecB)
HLT: I7X12_00715(wecB)
HME: HFX_6231(wecB)
HALE: G3A49_06295(wecB)
HSS: J7656_09670(wecB)
HALG: HUG10_14630(wecB)
HALU: HUG12_21355(wecB)
NMG: Nmag_0676
NEV: NTE_02143
NDV: NDEV_0205(wecB2)
 » show all
Reference
PMID:8939432
  Authors
Burrows LL, Charter DF, Lam JS
  Title
Molecular characterization of the Pseudomonas aeruginosa serotype O5 (PAO1) B-band lipopolysaccharide gene cluster.
  Journal
Mol Microbiol 22:481-95 (1996)
DOI:10.1046/j.1365-2958.1996.1351503.x
  Sequence
[pae:PA3148]
Reference
  Authors
Westman EL, McNally DJ, Charchoglyan A, Brewer D, Field RA, Lam JS
  Title
Characterization of WbpB, WbpE, and WbpD and reconstitution of a pathway for the biosynthesis of UDP-2,3-diacetamido-2,3-dideoxy-D-mannuronic acid in Pseudomonas aeruginosa.
  Journal
J Biol Chem 284:11854-62 (2009)
DOI:10.1074/jbc.M808583200
LinkDB

KEGG   ENZYME: 5.1.3.23
Entry
EC 5.1.3.23                 Enzyme                                 
Name
UDP-2,3-diacetamido-2,3-dideoxyglucuronic acid 2-epimerase;
UDP-GlcNAc3NAcA 2-epimerase;
UDP-alpha-D-GlcNAc3NAcA 2-epimerase;
2,3-diacetamido-2,3-dideoxy-alpha-D-glucuronic acid 2-epimerase;
WbpI;
WlbD
Class
Isomerases;
Racemases and epimerases;
Acting on carbohydrates and derivatives
Sysname
2,3-diacetamido-2,3-dideoxy-alpha-D-glucuronate 2-epimerase
Reaction(IUBMB)
UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-glucuronate = UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-mannuronate [RN:R09600]
Reaction(KEGG)
R09600
Substrate
UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-glucuronate [CPD:C19725]
Product
UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-mannuronate [CPD:C19745]
Comment
This enzyme participates in the biosynthetic pathway for UDP-alpha-D-ManNAc3NAcA (UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-mannuronic acid), an important precursor of the B-band lipopolysaccharide of Pseudomonas aeroginosa serotype O5 and of the band-A trisaccharide of Bordetella pertussis, both important respiratory pathogens [1]. The enzyme is highly specific as UDP-alpha-D-GlcNAc, UDP-alpha-D-GlcNAcA (UDP-2-acetamido-2-deoxy-alpha-D-glucuronic acid) and UDP-alpha-D-GlcNAc3NAc (UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-glucose) cannot act as substrates [1].
History
EC 5.1.3.23 created 2007
Pathway
ec00520  Amino sugar and nucleotide sugar metabolism
ec00541  O-Antigen nucleotide sugar biosynthesis
ec01100  Metabolic pathways
Orthology
K13019  UDP-GlcNAc3NAcA epimerase
Genes
PLUplu4804(wblH)
PLUMA4R40_23895
PAYPAU_04319(wblH)
PTTVY86_07555
PAKHB0X70_24585
PLUICE143_24625
AVTNCTC3438_01782(mnaA)
PAEPA3148(wbpI)
PAEVN297_3260
PAEIN296_3260
PAECM802_3258
PAEOM801_3125
PDRH681_23245
PSESPSCI_2869
PANHHU763_007170(wecB)
MARIACP86_02290
MARAD0851_05390
MARJMARI_04700(wbpI)
ADSFPL17_13915
SSESsed_2967
SGLAFJ709_05420
SVMKDH10_000090(wecB)
PPISB1L02_14620
PVBJ5X90_03260(wecB)
AAUSEP12_05170
LALAT746_12790
CATEC2869_15630
CBSCOXBURSA331_A1108
CBDCBUD_0907
CBGCbuG_1159(wecB)
CBCCbuK_0710(wecB)
CEYCleRT_10730
LSSNCTC12082_00069(wecB)
FRXF7310_06795
CYYCPC19_11130
THIMKFB96_04765(wecB)
TNITVNIR_0699(wecB_[C])
TTITHITH_05805
HTTHZS52_20515(wecB)
MMWMmwyl1_0835
MPRIMP3633_3239
MFOIJSY38_06670(wecB)
TORR615_06315
MGEOCFI10_13585
OMEOLMES_5518
SUTRL0B52_03945(wecB)
VMSLVJ82_06325(wecB)
LHKLHK_02802
PPNODA70_17285
LMIRNCTC12852_00313(mnaA_2)
BPEBP0090(bplD)
BPCBPTD_0086(bplD)
BPERBN118_0159(wlbD)
BPETB1917_0093(bplD)
BPEUQ425_2030(bplD)
BPARBN117_0150(wlbD)
BPABPP0152(bplD)
BBHBN112_3259(wlbD)
BBRBB0152(bplD)
BBMBN115_0141(wlbD)
BBXBBS798_0151(bplD)
BPTBpet4819(wlbD)
BHOD560_1331
BHMD558_1320
BHZACR54_00107(wbpI)
BTRMSAMEA390648701339(wlbD)
BPDZBBN53_20155
TEQTEQUI_1017
TEAKUI_0418
TEGKUK_0136
OUEI6G29_01430(wecB)
AAVAave_0953
ACKC380_07320
DLAI6G47_27680(wecB)
HYLLPB072_07130
MASWAM586_10875
TTWLCC91_03265(wecB)
HMSHMU06640
HBIHBZC1_15210
HETBBW65_04710
HCLNCTC13205_01069(mnaA)
HSHNHP194022_04670(wbpI)
WSUWS2189(WBPI)
TDNSuden_1418
CCOCCC13826_0521
CBLACBLAS_0721
ABUAbu_0692
PACOAACT_0957
HBVABIV_0881
GLOGlov_1505
GSBGSUB_15300
GPLM1B72_07930(wecB)
PEFA7E78_01570
DHYDESAM_20348
DDNDND132_2429
PSEFPSDVSF_24170
DSXGD604_09830
DSFUWK_02413
DEOCAY53_06115
DOLDole_1828
DWDDSCW_06940
DAODesac_2653
EAAI862_07330
MESPC1M53_01175
PMOBHG718_00065(wecB)
RBSRHODOSMS8_00383(wbpI)
AGCBSY240_4586
SZOK8M09_00485(wecB)
BRKCWS35_31810
BQBJ4P68_0006725(wecB)
MIVC4E04_13610 C4E04_13650
MICOGDR74_06705
HNIW911_00410
CMBCSW64_01275
SPOTG6548_17145(wecB)
PZHCX676_22395
HBCAEM38_13070 AEM38_13090
SPHOC3E99_07045
SPHUSPPYR_1658(wbpI)
PHAOHF685_11090(wecB)
ERRDVR09_11335
MAIMICA_1024
MANA11S_979
BDCDOE51_07915
SBFJCM31447_25060
BMETBMMGA3_15100
BDAFSZ17_21460
BACIB1NLA3E_20895
BONA361_24855
CSUAIM538_21360(wecB)
CFIRNAF01_22635(wecB)
CSOALIS82_24390(wecB)
GKAGK3162
GTEGTCCBUS3UF5_35310
GTKGT3570_15435
GTMGT3921_03270
BCALCWI35_12110
GYCGYMC61_3253
GYAGYMC52_3284
GCTGC56T3_3173
GGHGHH_c32370(mnaA)
GELIB49_07975
GSEGT50_07665
GZAIC807_11880(wecB)
PTBDER53_03255(wecB)
AAMYGFC30_485
VNECFK40_05105
LAOAOX59_11995
AQTFN924_03245
PSYHD0S48_07325
PSYOPB01_04645
RUEDT065_00075
MARYLAU42_03945(wecB)
PODPODO_28510
PNPIJ22_38280
PALBEJC50_29130
ATHEK3F53_17210(wecB)
CHEBHH215_20205(wecB)
LFBC1X05_15860
TVUAB849_005655
KPULGXN76_15365(wecB)
KEBGXN75_16725(wecB)
PABSJIR001_30170
CBOCBO3100
CBACLB_3129
CBHCLC_3002
CBYCLM_3506
CBLCLK_2494
CBKCLL_A3182
CBBCLD_1440
CBICLJ_B3366
CBTCLH_2927
CBFCLI_3159
CBMCBF_3148
CBJH04402_03177
CBECbei_4627
CBZCbs_4627
CBEILF65_05170
CKLCKL_3166
CKRCKR_2804
CLJCLJU_c34070
CCBClocel_3137
CSRCspa_c53520
CSBCLSA_c41270
CAHCAETHG_1305(wecB)
CSQCSCA_4791
CLDCLSPO_c18630 CLSPO_c31990
CCKCcar_17245
CBUTATN24_15745
CTYKCTK_C08720
CEUA7L45_12065
CTAEBGI42_12630
CDRKB9W14_20915
CDYF3K33_23555
CFERD4Z93_01765
CGASJ1C67_09865(wecB)
CLOSDMR38_17075
CGELpsyc5s11_49940
HHWNCTC503_01993(wecB)
RBPB6259_08160
CCELCCDG5_0710
EHAEthha_0669
CAPREQM14_12865
CAMLH6X83_09690(wecB)
CLFGJQ69_02340
CFEMHCR03_17330(wecB)
DORDesor_5330
DAIDesaci_4441
DMIDesmer_4332
PTHPTH_0384(WecB) PTH_1103(WecB)
DFGB0537_15540
DKUDesku_0874
AACXDEACI_0260
ELMELI_2561
SAYTPY_3671(wecB)
SAPSulac_3370
STHRBXT84_14970
MDVC5Q96_07715
TTETTE0661(WecB2)
MASMahau_0358
TBZBK011_02350
BSOLFSW04_03495
CWOCwoe_5917
PARNNBH00_24920(wecB)
SBAEDSM104329_04159(wbpI_1) DSM104329_05200(wbpI_2)
ELEElen_0637
EUZDVS28_a1719
HHGXM38_017570(wbpI)
GLPGlo7428_3721
OXYHCG48_01150(wecB)
GEIGEI7407_2308
GLJGKIL_0481(wecB)
CALHIJ00_16800
DEWDGWBC_0899
DFODform_01826(wecB)
RRSRoseRS_4430
RCARcas_0784
CAGCagg_0816 Cagg_1972
PSUBPelsub_P0628
CAPCLDAP_36180
THUGKNN16_05605(wecB)
DSWQR90_12670
DRDLMT64_11870(wecB)
TTHTT_C0285
PUVPUV_00130
AHELQ31a_45020(wbpI_1)
LCREPla8534_69410(wbpI)
PBSPlabr_1618
TPEDTPE_0207
TRMJO41_03110
TRZGWP43_02850
TMEDDWB79_01350
SPEREW093_13210 EW093_13440
TPXTurpa_0308
ABAAcid345_3306
GMAAciX8_3530
TRSTerro_1265
TALBFTW19_11825
FCII6I83_02405(wecB)
ACOAmico_1720
TLITlie_1813
AMOAnamo_1187
BUNBun01g_30650(wbpI)
BSTEK6V31_02460(wecB)
PPNPalpr_1323
PGOLK6V26_13515(wecB)
TFOBFO_2566
TOHBCB71_09295
OSPOdosp_0942
BVIRI6J59_01690(wecB) I6J59_14280(wecB)
TTZFHG85_09800
BACCBRDCF_p1451(wecB)
DORIFH5T_09075
RMGRhom172_0568
RBARAWN76_007345
CPICpin_4757
NIAA8C56_08555
FLASY85_01715
PGINFRZ67_02945
SBXCA265_19270
SPIBG8759_15505(wecB)
RUNDR864_23725
FKAKM029_13900(wecB)
CAPHCGC49_04830
ZGAZOBELLIA_1741(wecB)
SPONHME9304_01541(wbpI)
TDIAUW17_08820
TENLPB136_00970
TMPF9Y86_02255 F9Y86_04655
LUTLupro_12975
LULLPB138_15100
WFUAXE80_02790
SALTAO058_00370
EMARD1013_01185
PSYNE9099_06875
ASAGFGM00_16585
FBEFF125_16525
CARHEGY05_16490
FTEFluta_0726 Fluta_2189
FLUCHH17_06355
CRMK6119_19005(wecB)
OHOOweho_1403
CHYDH4K34_02735(wecB)
PTANCRYO30217_01158(wbpI_2)
SHYRLA303_04925(wecB)
BBAUAEM51_07985
MROMROS_2673
CPRVCYPRO_2717
CACICLOAM1218(wecB)
SAFSULAZ_0353
TMMTmari_0610
TMITHEMA_01615
TMWTHMA_0626
TMQTHMB_0626
TMXTHMC_0626
TPTTpet_0300 Tpet_0308
TNPTnap_0392 Tnap_0427
TRQTRQ2_0326
THQT2812B_01620
THZCELL2_01685
TLETlet_1207
TTATheth_1610
PHYAJ81_08730
TMETmel_0366
THPBG95_04935
THERY592_05005
FNOFnod_0568
FPEFerpe_0132
FIANA23_00760(wecB)
OCYOSSY52_03120
PMOPmob_0933 Pmob_1288
MPZMarpi_1253
MARNLN42_06735
KOLKole_1631
ASACATHSA_0040
CNICalni_1804
DTHDICTH_0427
DTUDtur_0574
ALAMRT761_00505(wbpI)
BIHBIP78_0584
MVNMevan_0198
MVOMvol_0232
MFIDSM1535_0247
METTCIT01_00335
PFIPFC_03140
PYCTQ32_02915
TSITSIB_2024
THMCL1_0830
THSTES1_1887
TTDA3L14_00440
THYA3L12_02955
THEIK1720_03030(wecB)
MBYMSBRM_0005 MSBRM_0792
MBWMSBRW_0943 MSBRW_2602
MBARMSBR2_0018
MBAKMSBR3_1166 MSBR3_1605
MMACMSMAC_1844
MVCMSVAZ_0005
MEKMSKOL_0025
MLSMSLAZ_1033 MSLAZ_1853 MSLAZ_1949
METMMSMTP_0932
MEFMSWH1_0729
MEQMSWHS_0769 MSWHS_0879
MSJMSSAC_1840 MSSAC_3566
MSZMSSIH_3108 MSSIH_3704
MSWMSSIT_2437 MSSIT_3165 MSSIT_3783
MBUMbur_2022
MHAZBHR79_03050
MHZMetho_1732
MTPMthe_1235
MCJMCON_2577(wecB)
MHUMhun_0382
MRTJKHC33_15080(wecB)
MEMMemar_1605
MBGBN140_0822(wecB1) BN140_2091(wecB3)
MEMAMMAB1_1080 MMAB1_2721
MCHKMchiMG62_18100
MFOMetfor_1414
RCIRCIX1930(wecB)
HJEHacjB3_10370
HALXM0R89_17775(wecB)
HAXZM0R88_18115(wecB)
HMUHmuk_2022
HALZE5139_13240
HALLLC1Hm_1346(wecB2)
HAZPGBQ70_13255
HALIBV210_19220
HPELHZS54_05795(wecB)
HLTI7X12_00715(wecB)
HMEHFX_6231(wecB)
HGIABY42_18105
HALEG3A49_06295(wecB)
HAERDU502_04900
HSSJ7656_09670(wecB)
HALGHUG10_14630(wecB)
HALUHUG12_21355(wecB)
HDABB347_15095
NMGNmag_0676
HXAHalxa_0889
NPENatpe_1304
HJTDVR14_15700
NGENatgr_0273
HRUHalru_0617 Halru_1009
HLRHALLA_13145
HLCCHINAEXTREME15900
NAJB1756_01065
NAGAArcMg_2149
NANAArc1_1538
NBGDV706_19910
NASGCU68_21140
ACFAciM339_0818
THBN186_08030
NVNNVIE_008910
NEVNTE_02143
NFNNFRAN_0194 NFRAN_0785(wecB)
NDVNDEV_0205(wecB2)
AGWQT03_C0001G0650
 » show all
Reference
1  [PMID:17346239]
  Authors
Westman EL, McNally DJ, Rejzek M, Miller WL, Kannathasan VS, Preston A, Maskell DJ, Field RA, Brisson JR, Lam JS.
  Title
Identification and biochemical characterization of two novel UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-glucuronic acid 2-epimerases from respiratory pathogens.
  Journal
Biochem J 405:123-30 (2007)
DOI:10.1042/BJ20070017
  Sequence
[pae:PA3148] [bpe:BP0090]
Reference
2
  Authors
Westman, E.L., McNally, D.J., Rejzek, M., Miller, W.L., Kannathasan, V.S., Preston, A., Maskell, D.J., Field, R.A., Brisson, J.R. and Lam, J.S.
  Title
Erratum report: Identification and biochemical characterization of two novel UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-glucuronic acid 2-epimerases from respiratory pathogens.
  Journal
Biochem J 405:625 (2007)
Reference
3  [PMID:11526328]
  Authors
Sri Kannathasan V, Staines AG, Dong CJ, Field RA, Preston AG, Maskell DJ, Naismith JH.
  Title
Overexpression, purification, crystallization and data collection on the Bordetella pertussis wlbD gene product, a putative UDP-GlcNAc 2'-epimerase.
  Journal
Acta Crystallogr D Biol Crystallogr 57:1310-2 (2001)
DOI:10.1107/S0907444901010885
Other DBs
ExplorEnz - The Enzyme Database: 5.1.3.23
IUBMB Enzyme Nomenclature: 5.1.3.23
ExPASy - ENZYME nomenclature database: 5.1.3.23
BRENDA, the Enzyme Database: 5.1.3.23
LinkDB

KEGG   REACTION: R09600
Entry
R09600                      Reaction                               
Name
2,3-diacetamido-2,3-dideoxy-alpha-D-glucuronate 2-epimerase
Definition
UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-glucuronate <=> UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-mannuronate
Equation
Reaction class
RC00290  C19725_C19745
Enzyme
Pathway
rn00520  Amino sugar and nucleotide sugar metabolism
rn00541  O-Antigen nucleotide sugar biosynthesis
rn01100  Metabolic pathways
rn01250  Biosynthesis of nucleotide sugars
Orthology
K13019  UDP-GlcNAc3NAcA epimerase [EC:5.1.3.23]
Other DBs
RHEA: 24767
LinkDB

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