Entry Name 2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one 2-D-glucosyltransferase;
Class Transferases;BRITE hierarchy
Sysname UDP-alpha-D-glucose:2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one 2-beta-D-glucosyltransferase
Reaction(IUBMB) (1) UDP-alpha-D-glucose + 2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one = UDP + (2R)-4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl beta-D-glucopyranoside [RN:
R04579 ];
(2) UDP-alpha-D-glucose + 2,4-dihydroxy-2H-1,4-benzoxazin-3(4H)-one = UDP + (2R)-4-hydroxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl beta-D-glucopyranoside [RN:
R07426 ]
Reaction(KEGG) Substrate UDP-alpha-D-glucose [CPD:
C00029 ];
2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one [CPD:
C04720 ];
2,4-dihydroxy-2H-1,4-benzoxazin-3(4H)-one [CPD:
C15770 ]
Product UDP [CPD:
C00015 ];
(2R)-4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl beta-D-glucopyranoside [CPD:
C04831 ];
(2R)-4-hydroxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl beta-D-glucopyranoside [CPD:
C15772 ]
Comment The enzyme is involved in the detoxification of the benzoxazinoids DIBOA (2,4-dihydroxy-2H-1,4-benzoxazin-3(4H)-one) and DIMBOA (2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one) which are stored as the respective non-toxic glucosides in the vacuoles in some plants, most commonly from the family of Poaceae (grasses). Benzoxazinoids are known to exhibit antimicrobial, antifeedant, and antiinsecticidal effects and are involved in the interaction of plants with other plants, insects, or microorganisms.
History EC 2.4.1.202 created 1992, modified 2012
Pathway ec00999 Biosynthesis of various plant secondary metabolites
ec01110 Biosynthesis of secondary metabolites
Orthology K13227 UDP-glucosyltransferase BX8/BX9
Genes OSA : 4334628 4342809 4350429
OGL : 127754441 127766058 127780103
ATS : 109735346 109736907 109754422 109779844
TDC : 119312581 119314690 119315414 119328279 119330805 119334371 119336035 119336866 119340106 119341052 119349903 119349904
TAES : 100682422 123114056 123123546 123147887 123150283 123150314 123159126 123160005 123167683 123172831
TUA : 125511240 125523142 125523860
LPER : 127292054 127330662
SBI : 110430107 8069138 8079707 8079708
ZMA : 100274317 100277344 103632152 109943562
MFLO : 136481097 136481105 136520960 136532876 136537698 136549539
SITA : 101752637 101753321 101778310 101780325 101784691 101785893
SVS : 117836233 117836591 117859511
PVIR : 120644461 120644612 120649240 120684540 120684928 120691830 120696099
PHAI : 112873443 112897861
» show all Taxonomy Reference Authors Bailey BA, Larson RL
Title Hydroxamic Acid glucosyltransferases from maize seedlings.
Journal Sequence Reference Authors von Rad U, Huttl R, Lottspeich F, Gierl A, Frey M.
Title Two glucosyltransferases are involved in detoxification of benzoxazinoids in maize.
Journal Sequence Other DBs ExPASy - ENZYME nomenclature database: 2.4.1.202
LinkDB All DBs
