KEGG   ORTHOLOGY: K13230
Entry
K13230            Tight     KO                                     

Name
BX7
Definition
2,4,7-trihydroxy-1,4-benzoxazin-3-one-glucoside 7-O-methyltransferase [EC:2.1.1.241]
Pathway
ko00402  Benzoxazinoid biosynthesis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00402 Benzoxazinoid biosynthesis
    K13230  BX7; 2,4,7-trihydroxy-1,4-benzoxazin-3-one-glucoside 7-O-methyltransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.241  2,4,7-trihydroxy-1,4-benzoxazin-3-one-glucoside 7-O-methyltransferase
     K13230  BX7; 2,4,7-trihydroxy-1,4-benzoxazin-3-one-glucoside 7-O-methyltransferase
Other DBs
RN: R08973
Genes
ZMA: 100147731(Bx7)
Reference
  Authors
Jonczyk R, Schmidt H, Osterrieder A, Fiesselmann A, Schullehner K, Haslbeck M, Sicker D, Hofmann D, Yalpani N, Simmons C, Frey M, Gierl A
  Title
Elucidation of the final reactions of DIMBOA-glucoside biosynthesis in maize: characterization of Bx6 and Bx7.
  Journal
Plant Physiol 146:1053-63 (2008)
DOI:10.1104/pp.107.111237
  Sequence
[zma:100147731]
LinkDB

KEGG   ENZYME: 2.1.1.241
Entry
EC 2.1.1.241                Enzyme                                 

Name
2,4,7-trihydroxy-1,4-benzoxazin-3-one-glucoside 7-O-methyltransferase;
BX7 (gene name);
OMT BX7
Class
Transferases;
Transferring one-carbon groups;
Methyltransferases
Sysname
S-adenosyl-L-methionine:(2R)-4,7-dihydroxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl beta-D-glucopyranoside 7-O-methyltransferase
Reaction(IUBMB)
S-adenosyl-L-methionine + (2R)-4,7-dihydroxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl beta-D-glucopyranoside = S-adenosyl-L-homocysteine + (2R)-4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl beta-D-glucopyranoside [RN:R08973]
Reaction(KEGG)
R08973
Substrate
S-adenosyl-L-methionine [CPD:C00019];
(2R)-4,7-dihydroxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl beta-D-glucopyranoside [CPD:C18062]
Product
S-adenosyl-L-homocysteine [CPD:C00021];
(2R)-4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl beta-D-glucopyranoside [CPD:C04831]
Comment
The enzyme is involved in the biosynthesis of the protective and allelophatic benzoxazinoid DIMBOA [(2R)-4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin] in some plants, most commonly from the family of Poaceae (grasses).
History
EC 2.1.1.241 created 2012
Pathway
ec00402  Benzoxazinoid biosynthesis
Orthology
K13230  2,4,7-trihydroxy-1,4-benzoxazin-3-one-glucoside 7-O-methyltransferase
Genes
ZMA: 100147731(Bx7)
Reference
1  [PMID:18192444]
  Authors
Jonczyk R, Schmidt H, Osterrieder A, Fiesselmann A, Schullehner K, Haslbeck M, Sicker D, Hofmann D, Yalpani N, Simmons C, Frey M, Gierl A
  Title
Elucidation of the final reactions of DIMBOA-glucoside biosynthesis in maize: characterization of Bx6 and Bx7.
  Journal
Plant Physiol 146:1053-63 (2008)
DOI:10.1104/pp.107.111237
  Sequence
[zma:100147731]
Other DBs
ExplorEnz - The Enzyme Database: 2.1.1.241
IUBMB Enzyme Nomenclature: 2.1.1.241
ExPASy - ENZYME nomenclature database: 2.1.1.241
BRENDA, the Enzyme Database: 2.1.1.241
LinkDB

KEGG   REACTION: R08973
Entry
R08973                      Reaction                               

Name
S-adenosyl-L-methionine:TRIBOA-glucoside 7-O-methyltransferase
Definition
S-Adenosyl-L-methionine + TRIBOA-glucoside <=> S-Adenosyl-L-homocysteine + DIMBOA-glucoside
Equation
Comment
O-methyltransferase BX7
Reaction class
RC00003  C00019_C00021
RC00392  C04831_C18062
Enzyme
Pathway
rn00402  Benzoxazinoid biosynthesis
Orthology
K13230  2,4,7-trihydroxy-1,4-benzoxazin-3-one-glucoside 7-O-methyltransferase [EC:2.1.1.241]
Other DBs
RHEA: 32102
LinkDB

DBGET integrated database retrieval system