KEGG   ORTHOLOGY: K13230
Entry
K13230            Tight     KO                                     
Symbol
BX7
Name
2,4,7-trihydroxy-1,4-benzoxazin-3-one-glucoside 7-O-methyltransferase [EC:2.1.1.241]
Pathway
map00402  Benzoxazinoid biosynthesis
map00999  Biosynthesis of various plant secondary metabolites
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00402 Benzoxazinoid biosynthesis
    K13230  BX7; 2,4,7-trihydroxy-1,4-benzoxazin-3-one-glucoside 7-O-methyltransferase
   00999 Biosynthesis of various plant secondary metabolites
    K13230  BX7; 2,4,7-trihydroxy-1,4-benzoxazin-3-one-glucoside 7-O-methyltransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.241  2,4,7-trihydroxy-1,4-benzoxazin-3-one-glucoside 7-O-methyltransferase
     K13230  BX7; 2,4,7-trihydroxy-1,4-benzoxazin-3-one-glucoside 7-O-methyltransferase
Other DBs
RN: R08973
Genes
ZMA: 100147731
Reference
  Authors
Jonczyk R, Schmidt H, Osterrieder A, Fiesselmann A, Schullehner K, Haslbeck M, Sicker D, Hofmann D, Yalpani N, Simmons C, Frey M, Gierl A
  Title
Elucidation of the final reactions of DIMBOA-glucoside biosynthesis in maize: characterization of Bx6 and Bx7.
  Journal
Plant Physiol 146:1053-63 (2008)
DOI:10.1104/pp.107.111237
  Sequence
[zma:100147731]
LinkDB

KEGG   ENZYME: 2.1.1.241
Entry
EC 2.1.1.241                Enzyme                                 
Name
2,4,7-trihydroxy-1,4-benzoxazin-3-one-glucoside 7-O-methyltransferase;
BX7 (gene name);
OMT BX7
Class
Transferases;
Transferring one-carbon groups;
Methyltransferases
Sysname
S-adenosyl-L-methionine:(2R)-4,7-dihydroxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl beta-D-glucopyranoside 7-O-methyltransferase
Reaction(IUBMB)
S-adenosyl-L-methionine + (2R)-4,7-dihydroxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl beta-D-glucopyranoside = S-adenosyl-L-homocysteine + (2R)-4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl beta-D-glucopyranoside [RN:R08973]
Reaction(KEGG)
R08973
Substrate
S-adenosyl-L-methionine [CPD:C00019];
(2R)-4,7-dihydroxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl beta-D-glucopyranoside [CPD:C18062]
Product
S-adenosyl-L-homocysteine [CPD:C00021];
(2R)-4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl beta-D-glucopyranoside [CPD:C04831]
Comment
The enzyme is involved in the biosynthesis of the protective and allelophatic benzoxazinoid DIMBOA [(2R)-4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin] in some plants, most commonly from the family of Poaceae (grasses).
History
EC 2.1.1.241 created 2012
Pathway
ec00402  Benzoxazinoid biosynthesis
ec00999  Biosynthesis of various plant secondary metabolites
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Orthology
K13230  2,4,7-trihydroxy-1,4-benzoxazin-3-one-glucoside 7-O-methyltransferase
Genes
ZMA100147731
Reference
1  [PMID:18192444]
  Authors
Jonczyk R, Schmidt H, Osterrieder A, Fiesselmann A, Schullehner K, Haslbeck M, Sicker D, Hofmann D, Yalpani N, Simmons C, Frey M, Gierl A
  Title
Elucidation of the final reactions of DIMBOA-glucoside biosynthesis in maize: characterization of Bx6 and Bx7.
  Journal
Plant Physiol 146:1053-63 (2008)
DOI:10.1104/pp.107.111237
  Sequence
[zma:100147731]
Other DBs
ExplorEnz - The Enzyme Database: 2.1.1.241
IUBMB Enzyme Nomenclature: 2.1.1.241
ExPASy - ENZYME nomenclature database: 2.1.1.241
BRENDA, the Enzyme Database: 2.1.1.241
LinkDB

KEGG   REACTION: R08973
Entry
R08973                      Reaction                               
Name
S-adenosyl-L-methionine:TRIBOA-glucoside 7-O-methyltransferase
Definition
S-Adenosyl-L-methionine + TRIBOA-glucoside <=> S-Adenosyl-L-homocysteine + DIMBOA-glucoside
Equation
Comment
O-methyltransferase BX7
Reaction class
RC00003  C00019_C00021
RC00392  C04831_C18062
Enzyme
Pathway
rn00402  Benzoxazinoid biosynthesis
rn00999  Biosynthesis of various plant secondary metabolites
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Orthology
K13230  2,4,7-trihydroxy-1,4-benzoxazin-3-one-glucoside 7-O-methyltransferase [EC:2.1.1.241]
Other DBs
RHEA: 32102
LinkDB

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