KEGG   ORTHOLOGY: K13317
Entry
K13317                      KO                                     
Symbol
eryBIII, tylCIII, tylC3
Name
NDP-4-keto-2,6-dideoxyhexose 3-C-methyltransferase [EC:2.1.1.-]
Pathway
map00523  Polyketide sugar unit biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
map01250  Biosynthesis of nucleotide sugars
Module
M00798  dTDP-L-mycarose biosynthesis
Reaction
R08933  S-adenosyl-L-methionine:dTDP-4-oxo-2,6-dideoxy-D-allose 3-C-methyltransferase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00523 Polyketide sugar unit biosynthesis
    K13317  eryBIII, tylCIII, tylC3; NDP-4-keto-2,6-dideoxyhexose 3-C-methyltransferase
Genes
NAH: F5544_22545
NGP: LTT66_33290
NSPU: IFM12276_32140
SANL: KZO11_29615
SAMB: SAM23877_5604(srm33)
SPRI: SPRI_0239
SALW: CP975_00170
SGM: GCM10017557_73590
SNR: SNOUR_10065(eryBIII)
SALU: DC74_6617
SALL: SAZ_34400
SALJ: SMD11_1674(eryBIII)
SGD: ELQ87_08065
SGF: HEP81_07904
SDW: K7C20_32590
SAUH: SU9_033055
SMOB: J7W19_17750
SANU: K7396_04505 K7396_33615
SCAE: IHE65_08960
SPRF: K4G22_25830
AER: AERYTH_15875
SEN: SACE_0731(eryBIII)
AACD: LWP59_17790
CCAZ: COUCH_15930
AEY: CDG81_13140
LEK: hrd7_23770
AG: AAD41823(tylCIII)
 » show all
Reference
PMID:10658660
  Authors
Bate N, Butler AR, Smith IP, Cundliffe E
  Title
The mycarose-biosynthetic genes of Streptomyces fradiae, producer of tylosin.
  Journal
Microbiology 146 ( Pt 1):139-46 (2000)
DOI:10.1099/00221287-146-1-139
  Sequence
[ag:AAD41823]
Reference
PMID:15984840
  Authors
Takahashi H, Liu YN, Chen H, Liu HW
  Title
Biosynthesis of TDP-l-mycarose: the specificity of a single enzyme governs the outcome of the pathway.
  Journal
J Am Chem Soc 127:9340-1 (2005)
DOI:10.1021/ja051409x
LinkDB

KEGG   REACTION: R08933
Entry
R08933                      Reaction                               
Name
S-adenosyl-L-methionine:dTDP-4-oxo-2,6-dideoxy-D-allose 3-C-methyltransferase
Definition
S-Adenosyl-L-methionine + dTDP-4-oxo-2,6-dideoxy-D-allose <=> S-Adenosyl-L-homocysteine + dTDP-3-methyl-4-oxo-2,6-dideoxy-D-glucose
Equation
C00019 + C11928 <=> C00021 + C18035
Reaction class
RC00003  C00019_C00021
RC01404  C11928_C18035
Enzyme
2.1.1.-
Pathway
rn00523  Polyketide sugar unit biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01250  Biosynthesis of nucleotide sugars
Module
M00798  dTDP-L-mycarose biosynthesis
Brite
Enzymatic reactions [BR:br08201]
 2. Transferase reactions
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.-
     R08933  S-Adenosyl-L-methionine + dTDP-4-oxo-2,6-dideoxy-D-allose <=> S-Adenosyl-L-homocysteine + dTDP-3-methyl-4-oxo-2,6-dideoxy-D-glucose
Orthology
K13317  NDP-4-keto-2,6-dideoxyhexose 3-C-methyltransferase [EC:2.1.1.-]
LinkDB

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