KEGG ORTHOLOGY: K13567

ORTHOLOGY: K13567

Entry

K13567                      KO

Symbol

ACVR1B, ALK4

Name

activin receptor type-1B [EC:2.7.11.30]

Pathway

map04060

Cytokine-cytokine receptor interaction

map04350

TGF-beta signaling pathway

map04550

Signaling pathways regulating pluripotency of stem cells

Disease

H00019

Pancreatic cancer

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04350 TGF-beta signaling pathway
    K13567  ACVR1B, ALK4; activin receptor type-1B
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K13567  ACVR1B, ALK4; activin receptor type-1B
09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    K13567  ACVR1B, ALK4; activin receptor type-1B
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K13567  ACVR1B, ALK4; activin receptor type-1B
Enzymes [BR:ko01000]
2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.30  receptor protein serine/threonine kinase
     K13567  ACVR1B, ALK4; activin receptor type-1B
Protein kinases [BR:ko01001]
Receptor serine/threonine kinases (RSTK): TKL group
  TGFBR1 family [OT]
   K13567  ACVR1B, ALK4; activin receptor type-1B

Other DBs

GO:

0016361

Genes

HSA:	91(ACVR1B)

PTR:	451911(ACVR1B)

PPS:	100978253(ACVR1B)

GGO:	101147783(ACVR1B)

PON:	100173725(ACVR1B)

PPYG:

129010197(ACVR1B)

NLE:	100607263(ACVR1B)

HMH:	116461691(ACVR1B)

SSYN:

129491049(ACVR1B)

MCC:	696587(ACVR1B)

MCF:	101865702(ACVR1B)

MTHB:

126931048

MNI:	105474334(ACVR1B)

CSAB:

103238330(ACVR1B)

CATY:

105580327(ACVR1B)

PANU:

101020254(ACVR1B)

TGE:	112635085(ACVR1B)

MLEU:

105555422(ACVR1B)

RRO:	104670653(ACVR1B)

RBB:	108521608(ACVR1B)

TFN:	117090103(ACVR1B)

PTEH:

111541982(ACVR1B)

CANG:

105503621(ACVR1B)

CJC:	100391614(ACVR1B)

SBQ:	101039430(ACVR1B)

CIMI:

108316105(ACVR1B)

ANAN:

105715818(ACVR1B)

CSYR:

103268415(ACVR1B)

MMUR:

105870287(ACVR1B)

LCAT:

123639821(ACVR1B)

ERUF:

138397089(ACVR1B)

PCOQ:

105818480(ACVR1B)

OGA:	100955645(ACVR1B)

MMU:	11479(Acvr1b)

MCAL:

110310452(Acvr1b)

MPAH:

110334711(Acvr1b)

RNO:	29381(Acvr1b)

MCOC:

116080007(Acvr1b)

ANU:	117718646(Acvr1b)

ASYL:

127667681(Acvr1b)

MUN:	110559138(Acvr1b)

CGE:	100764812(Acvr1b)

MAUA:

101831380(Acvr1b)

PROB:

127226096(Acvr1b)

PLEU:

114696657(Acvr1b)

PMAV:

102927129(Acvr1b)

MORG:

121444245(Acvr1b)

MFOT:

126488781

AAMP:

119823040(Acvr1b)

CNL:	130888700(Acvr1b)

NGI:	103739584(Acvr1b)

HGL:	101709452(Acvr1b)

CPOC:

100733441(Acvr1b)

CCAN:

109685525(Acvr1b)

DORD:

105987417(Acvr1b)

DSP:	122098383(Acvr1b)

DMER:

138840947(Acvr1b)

PLOP:

125364542(Acvr1b)

NCAR:

124983852

MMMA:

107148646(Acvr1b)

ITI:	101965240(Acvr1b)

OCU:

100345068

OPI:	101527295(ACVR1B)

OCZ:	121155885 121167232(ACVR1B)

TUP:	102490297(ACVR1B)

GVR:	103585225(ACVR1B)

CFA:	486537(ACVR1B)

CLUD:

112667243(ACVR1B)

VVP:	112921156(ACVR1B)

VLG:	121479981(ACVR1B)

NPO:	129517281(ACVR1B)

AML:	100482103(ACVR1B)

UMR:	103675499(ACVR1B)

UAH:	113257594(ACVR1B)

UAR:	123794730(ACVR1B)

ELK:

111157829

LLV:

125106611

MPUF:

101689981(ACVR1B)

MNP:	132019694(ACVR1B)

MLK:	131838744(ACVR1B)

NVS:	122892676(ACVR1B)

ORO:	101376142(ACVR1B)

EJU:	114225800(ACVR1B)

ZCA:	113921741(ACVR1B)

MLX:	118008827(ACVR1B)

NSU:	110593501(ACVR1B)

LWW:	102743689(ACVR1B)

FCA:	101097654(ACVR1B)

PYU:	121038552(ACVR1B)

PCOO:

112867804(ACVR1B)

PBG:	122473415(ACVR1B)

PVIV:

125170078(ACVR1B)

LRUF:

124501228

LGF:	123592108(ACVR1B)

AJU:

106969206

PTG:	102971536(ACVR1B)

PPAD:

109249132(ACVR1B)

PUC:

125919067

PLEZ:

122224570(ACVR1B)

HHV:	120237936(ACVR1B)

BTA:	539315(ACVR1B)

BOM:	102287655(ACVR1B)

BIU:	109559077(ACVR1B)

BBUB:

102393815(ACVR1B)

BKE:	129654286(ACVR1B)

BBIS:

105001535(ACVR1B)

CHX:	102186186(ACVR1B)

OAS:	101113836(ACVR1B)

BTAX:

128048879(ACVR1B)

CSUM:

138078843(ACVR1B)

ODA:	120858243(ACVR1B)

CCAD:

122427222(ACVR1B)

MREE:

136167113(ACVR1B)

OVR:	110131791(ACVR1B)

MBEZ:

129535762(ACVR1B)

SSC:	100152462(ACVR1B)

CFR:	102510501(ACVR1B)

CBAI:

105076250(ACVR1B)

CDK:	105100385(ACVR1B)

VPC:	102529123(ACVR1B)

BACU:

103020048(ACVR1B)

BMUS:

118901903(ACVR1B)

LVE:	103076167(ACVR1B)

OOR:	101273958(ACVR1B)

LALB:

132529539(ACVR1B)

GMF:	115849986(ACVR1B)

DDP:	132433694(ACVR1B)

DLE:	111173982(ACVR1B)

PCAD:

114486512

PSIU:

116760459(ACVR1B)

PPHC:

136130555(ACVR1B)

NASI:

112394047(ACVR1B)

ECB:	100062619(ACVR1B)

EPZ:	103561300(ACVR1B)

EAI:	106835238(ACVR1B)

MYB:	102246021(ACVR1B)

MYD:	102765939(ACVR1B)

MMYO:

118650133(ACVR1B)

MLF:	102427872(ACVR1B)

MDT:	132227614(ACVR1B)

MYUM:

139007114(ACVR1B)

PKL:	118728513(ACVR1B)

EFUS:

103285308(ACVR1B)

MNA:	107528284(ACVR1B)

DRO:	112318392(ACVR1B)

SHON:

118976397(ACVR1B)

AJM:	119043374(ACVR1B)

PDIC:

114512795(ACVR1B)

PHAS:

123812595(ACVR1B)

MMF:	118624469(ACVR1B)

PPAM:

129084835(ACVR1B)

HAI:	109371428(ACVR1B)

RFQ:	117028582(ACVR1B)

PALE:

102885131(ACVR1B)

PGIG:

120602113(ACVR1B)

PVP:	105307013(ACVR1B)

RAY:	107509821(ACVR1B)

MJV:	108398274(ACVR1B)

TOD:	119247941(ACVR1B)

SARA:

101541400(ACVR1B)

SFUM:

130029071(ACVR1B)

SETR:

126022502(ACVR1B)

LAV:	100654281(ACVR1B)

TMU:

101346016

ETF:	101660173(ACVR1B)

DNM:	101410737(ACVR1B)

GAS:	123248649(ACVR1B)

SHR:	100913702(ACVR1B)

AFZ:

127539387

PCW:	110194062(ACVR1B)

TVP:	118850132(ACVR1B)

PBRV:

138164619(ACVR1B)

MLAO:

141514794(ACVR1B)

OAA:	100090625(ACVR1B)

TACU:

119933285(ACVR1B)

GGA:	768878(ACVR1B)

PCOC:

116239645(ACVR1B)

MGP:	116217774(ACVR1B)

CJO:	107325721(ACVR1B)

NMEL:

110389194(ACVR1B)

APLA:

101796697(ACVR1B)

AACU:

137845864(ACVR1B)

ACYG:

106047733(ACVR1B)

CATA:

118260236(ACVR1B)

AFUL:

116499988(ACVR1B)

TGU:	115491409(ACVR1B)

LSR:	110480397(ACVR1B)

SCAN:

103825003(ACVR1B)

PMOA:

120499485(ACVR1B)

OTC:	121334304(ACVR1B)

PRUF:

121356344(ACVR1B)

ATRC:

139604808(ACVR1B)

FAB:	101809573(ACVR1B)

OMA:	130265770(ACVR1B)

PHI:	102105645(ACVR1B)

PMAJ:

107198600(ACVR1B)

CCAE:

111940581(ACVR1B)

CBRC:

103611884(ACVR1B)

ACOE:

138100086(ACVR1B)

ETL:	114070438(ACVR1B)

ZLE:	135459092(ACVR1B)

ACHL:

103799693(ACVR1B)

SVG:	106862684(ACVR1B)

MMEA:

130586315(ACVR1B)

HRT:	120764437(ACVR1B)

SATI:

136372792(ACVR1B)

CFAI:

136303805(ACVR1B)

CCIC:

134054918(ACVR1B)

FPG:	101924360(ACVR1B)

FCH:	102046018(ACVR1B)

CCRI:

104169136

NNT:

104405000

SHAB:

115618673(ACVR1B)

ACUN:

113490984(ACVR1B)

SURA:

141936722(ACVR1B)

TALA:

104367705(ACVR1B)

ACHC:

115350993(ACVR1B)

HALD:

104318197(ACVR1B)

HLE:	104831146(ACVR1B)

AGEN:

126046378

HHAR:

128151827(ACVR1B)

BBUT:

142040998(ACVR1B)

GCL:

127028374

CSTI:

104556991(ACVR1B)

LDI:	104350312(ACVR1B)

MNB:	103768670(ACVR1B)

DPUB:

104305500(ACVR1B)

PPUS:

135174338(ACVR1B)

AVIT:

104280520(ACVR1B)

BRHI:

104499482(ACVR1B)

EGZ:	104122501(ACVR1B)

NNI:	104011977(ACVR1B)

PCRI:

104037324(ACVR1B)

PCAO:

104053361(ACVR1B)

PADL:

103913389(ACVR1B)

AFOR:

103894911(ACVR1B)

FGA:	104078950(ACVR1B)

CBOR:

142073767(ACVR1B)

GSTE:

104260065(ACVR1B)

CBOY:

140644390(ACVR1B)

MAME:

142420957(ACVR1B)

CLV:	102089002(ACVR1B)

CNIC:

136000495(ACVR1B)

MUI:	104543080(ACVR1B)

PGUU:

104462854(ACVR1B)

PLET:

104624160

EHS:

104509274

CMAC:

104486282(ACVR1B)

CUCA:

104057934(ACVR1B)

TEO:

104379394

BREG:

104642647(ACVR1B)

GAME:

129197983(ACVR1B)

OHA:	104336162(ACVR1B)

CPEA:

104385602(ACVR1B)

CVF:	104284797(ACVR1B)

RTD:	128901236(ACVR1B)

CRID:

134526784(ACVR1B)

LMIC:

141733913(ACVR1B)

NARQ:

141476316(ACVR1B)

AAM:	106499430(ACVR1B)

AROW:

112975217(ACVR1B)

NPD:	112950321(ACVR1B)

TGT:	104566346(ACVR1B)

DNE:	112991668(ACVR1B)

SCAM:

104144037(ACVR1B)

ASN:	102386528(ACVR1B)

AMJ:	102572242(ACVR1B)

CPOO:

109324456(ACVR1B)

PSS:	102454243(ACVR1B)

CIZ:	142003304(ACVR1B)

CMY:	102936225(ACVR1B)

CCAY:

125627547(ACVR1B)

LKP:	140901102(ACVR1B)

NDS:	141974809(ACVR1B)

DCC:	119845881(ACVR1B)

CPIC:

101945338(ACVR1B)

TST:	117888639(ACVR1B)

CABI:

116827804(ACVR1B)

MRV:	120391030(ACVR1B)

ACS:	100554341(acvr1b)

ASAO:

132768303(ACVR1B)

PVT:	110074424(ACVR1B)

SUND:

121922394(ACVR1B)

PBI:	103063353(ACVR1B)

PMUR:

107291020(ACVR1B)

CTIG:

120305450(ACVR1B)

TSR:	106556935(ACVR1B)

PGUT:

117662784(ACVR1B)

PCAE:

139310659(ACVR1B)

APRI:

131193551(ACVR1B)

PTEX:

113447351(ACVR1B)

NSS:	113420177(ACVR1B)

VKO:	123019247(ACVR1B)

PRAF:

128407092(ACVR1B)

ZVI:	118079300(ACVR1B)

HCG:	128345731(ACVR1B)

GJA:	107108994(ACVR1B)

STOW:

125428503(ACVR1B)

EMC:	129327294(ACVR1B)

XLA:	108708537(acvr1b.L) 399454(acvr1b.S)

XTR:	733849(acvr1b)

NPR:	108798620(ACVR1B)

RTEM:

120929602(ACVR1B)

ACAT:

141127543(ACVR1B)

PADS:

140329433(ACVR1B)

BBUF:

120995939(ACVR1B)

BGAR:

122930981(ACVR1B)

DTC:	141094430(ACVR1B)

PWL:	138292130(ACVR1B)

MUO:	115465956(ACVR1B)

GSH:	117357452(ACVR1B)

DRE:	30183(acvr1ba) 559222(acvr1bb)

SRX:	107708570 107708859 107716207 107752870

SANH:

107681940 107686786 107690814 107695803

SGH:	107554883 107563637 107570552 107582342

CCAR:

109083146 109088362 109094138(acvr1bb)

CAUA:

113050990 113065481 113070552 113091311

CGIB:

127945166 127959160 128011762 128015263

PTET:

122328572 122329051(acvr1ba) 122346664(acvr1bb)

LROH:

127154874(acvr1ba) 127166591(acvr1bb)

GRF:	141290760(acvr1ba) 141346357(acvr1bb)

OMC:	131532391(acvr1ba) 131541936

PPRM:

120463047(acvr1ba) 120467938(acvr1bb)

RKG:	130073555(acvr1ba) 130100574(acvr1bb)

MAMB:

125259814(acvr1ba) 125274085(acvr1bb)

CIDE:

127505553 127514075

CERY:

137009089(acvr1ba) 137011621(acvr1bb)

MASI:

127419162 127420216 127445904 127448677

TROS:

130556786(acvr1bb) 130571904(acvr1ba)

TDW:	130409200(acvr1ba) 130424462(acvr1bb)

MANU:

129430805(acvr1ba) 129450179(acvr1bb)

PDAB:

135775437(acvr1ba) 135783215(acvr1bb)

IPU:	108271957(acvr1bb) 108275853(acvr1ba)

IFU:	128614467(acvr1bb) 128619793(acvr1ba)

PHYP:

113529337 113530838

SMEO:

124392335(acvr1bb)

TFD:	113642667 113658176(acvr1ba)

TVC:	132844528(acvr1bb) 132861962(acvr1ba)

CGAR:

128510433(acvr1ba) 128526486

NGRA:

132885137 132897111(acvr1ba)

TRN:	134316880 134333079(acvr1ba)

AMEX:

103027116(acvr1bb) 103042879(acvr1ba)

CMAO:

118808405 118822589(acvr1ba)

EEE:	113581536 113584452

CHAR:

105897348(acvr1ba) 105901897

SPIL:

134087132(acvr1ba) 134091888

ASAD:

121707094 121713460(acvr1ba)

TRU:	101062677(acvr1b) 101064200

TFS:	130524093 130529883(acvr1ba)

TNG:	GSTEN00027258G001 GSTEN00028084G001

LCO:	104932530 104938405

NCC:	104941416 104956875

TBEN:

117489580 117494265(acvr1ba)

CGOB:

115007915 115010633

PGEO:

117446429 117449504(acvr1ba)

GACU:

117541876(acvr1ba) 117551054

EMAC:

134865512(acvr1ba) 134883040

ELY:	117257141 117258425(acvr1ba)

EFO:	125889710 125891533(acvr1ba)

PLEP:

121946816(acvr1ba) 121955783

SLUC:

116038946(acvr1ba) 116041661

ECRA:

117943916 117947773(acvr1ba)

ESP:	116688382 116692908

PFLV:

114553596 114558805

GAT:	120829102(acvr1ba) 120835369

PPUG:

119206534(acvr1ba) 119229447

AFB:	129099486(acvr1ba) 129105381

CLUM:

117730695 117733259(acvr1ba)

PSWI:

130199682(acvr1ba) 130208868

CANA:

137796894 137799957

CVE:	137879452 137889108(acvr1ba)

MSAM:

119885701 119905633(acvr1ba)

SCHU:

122867069 122883463(acvr1ba)

EARM:

139282693 139288370(acvr1ba)

CUD:	121506989 121517563(acvr1ba)

SPUL:

138589419(acvr1ba) 138606140

LMIX:

132977757 132989225(acvr1ba)

HTC:	141784871 141799122(acvr1ba)

ALAT:

119020494 119023107(acvr1ba)

ASTR:

137594877 137610966(acvr1ba)

PKLU:

139209333(acvr1ba) 139215006

MZE:	101476960 101485924

ONL:	100699905 100709886

OAU:	116325837(acvr1ba) 116333869

OLA:	101171991(acvr1b)

OML:	112159274(acvr1ba)

CSAI:

133457187(acvr1ba)

XMA:	102224663(acvr1b)

XCO:	114143630(acvr1b)

XHE:	116727216(acvr1b)

PRET:

103467353(acvr1b)

PFOR:

103141132(acvr1b)

PLAI:

106959282(acvr1b)

PMEI:

106921546(acvr1b)

GAF:	122828643(acvr1ba)

PPRL:

129372511(acvr1ba)

CVG:	107086775(acvr1b)

CTUL:

119782015(acvr1ba)

GMU:	124877032(acvr1ba)

NFU:	107390884(acvr1b)

KMR:	108235245(acvr1ba)

ALIM:

106524891(acvr1b)

NWH:	119417624(acvr1ba)

AOCE:

111566612 111577291(acvr1ba)

EJA:	138192714(acvr1ba) 138201328

BFRE:

138614923(acvr1ba) 138626419

MCEP:

125019963(acvr1ba)

CSEM:

103385074(acvr1b) 103385953

POV:	109629242 109630841

SSEN:

122767838 122777103(acvr1ba)

SSOE:

131461275 131468473(acvr1ba)

HHIP:

117761295 117764388(acvr1ba)

HSP:	118105475 118111256(acvr1ba)

PPLT:

128442604(acvr1ba) 128452110

SMAU:

118308946 118316367(acvr1ba)

LCF:	108876546 108881466

SDU:	111219022 111221636

SLAL:

111667734 111668985

XGL:	120804195(acvr1ba) 120807006

HCQ:	109522424 109531376

SSCV:

125976678 125989449(acvr1ba)

SBIA:

133505518(acvr1ba) 133507664

PEE:	133402252(acvr1ba) 133409145

PTAO:

133478473(acvr1ba) 133483762

BPEC:

110164558 110168376

ENY:	140363410(acvr1ba) 140366076

MALB:

109964499 109971156

BSPL:

114856334 114858182(acvr1ba)

SJO:	128356055 128357268(acvr1ba)

SSCO:

133987533(acvr1ba) 134002994

TTY:	137181643 137184481(acvr1ba)

GMH:	115547247 115557571

SASA:

100195539(acv1b) 106565530 106567045(ACV1B) 106583225

STRU:

115150572 115165502 115167839 115207835

OTW:	112217555 112221709 112249358 112254605

OMY:	110491966 110494313 110528117 110532699

OGO:	124002561 124031280 124032280

ONE:	115102571 115132487 115139854 115143169

OKI:	109869143 109878417 109891141 109904641

OKE:	118360112 118360674 118388569 118400297

OMM:	135504022 135528476 135539980 135541935

OCLA:

139368413 139371078 139413527 139416830

SALP:

111966751 111966799 111970084 111976988

SNH:	120025260 120059119 120061019 120065188

SFON:

129815521 129829673 129848004 129860552

CCLU:

121537892 121545863 121575257 121577616

ELS:	105013550 105017213

OEP:	134018533(acvr1ba) 134023419

SFM:	108918425 108939255(acvr1b)

PKI:	111854507 111860626

AANG:

118208100(acvr1ba) 118210652

AROT:

135234421(acvr1ba) 135237569

CCOG:

133110183 133138375(acvr1ba)

LOC:	102683440(acvr1b)

PSPA:

121308825

ARUT:

117401025 117962264

PSEX:

120524835(acvr1ba)

LCM:	102357203(ACVR1B)

CMK:	103174184 103176569

RTP:	109912784 109924196

CPLA:

CPUN:

HOC:

LERI:

HAKA:

HRO:	HELRODRAFT_192976

GAE:

121387758

» show all

Reference

PMID:8397373

Authors

ten Dijke P, Ichijo H, Franzen P, Schulz P, Saras J, Toyoshima H, Heldin CH, Miyazono K

Title

Activin receptor-like kinases: a novel subclass of cell-surface receptors with predicted serine/threonine kinase activity.

Journal

Oncogene 8:2879-87 (1993)

Sequence

[hsa:91]

LinkDB

ORTHOLOGY: K13568

Entry

K13568                      KO

Symbol

ACVR1C, ALK7

Name

activin receptor type-1C [EC:2.7.11.30]

Pathway

map04060

Cytokine-cytokine receptor interaction

map04350

TGF-beta signaling pathway

map04550

Signaling pathways regulating pluripotency of stem cells

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04350 TGF-beta signaling pathway
    K13568  ACVR1C, ALK7; activin receptor type-1C
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K13568  ACVR1C, ALK7; activin receptor type-1C
09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    K13568  ACVR1C, ALK7; activin receptor type-1C
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K13568  ACVR1C, ALK7; activin receptor type-1C
Enzymes [BR:ko01000]
2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.30  receptor protein serine/threonine kinase
     K13568  ACVR1C, ALK7; activin receptor type-1C
Protein kinases [BR:ko01001]
Receptor serine/threonine kinases (RSTK): TKL group
  TGFBR1 family [OT]
   K13568  ACVR1C, ALK7; activin receptor type-1C

Other DBs

GO:

0016361

Genes

HSA:	130399(ACVR1C)

PTR:	470564(ACVR1C)

PPS:	100968350(ACVR1C)

GGO:	101153902(ACVR1C)

PON:	100455362(ACVR1C)

PPYG:

129031930(ACVR1C)

NLE:	100593217(ACVR1C)

HMH:	116810781(ACVR1C)

SSYN:

129489461(ACVR1C)

MCC:	697826(ACVR1C)

MCF:	102131774(ACVR1C)

MTHB:

126932662

MNI:	105493212(ACVR1C)

CSAB:

103217134(ACVR1C)

CATY:

105576108(ACVR1C)

PANU:

101005651(ACVR1C)

TGE:	112636214(ACVR1C)

MLEU:

105548015(ACVR1C)

RRO:	104662237(ACVR1C)

RBB:	108544121(ACVR1C)

TFN:	117094982(ACVR1C)

PTEH:

111546098(ACVR1C)

CANG:

105516847(ACVR1C)

CJC:	100407436(ACVR1C)

SBQ:	101051973(ACVR1C)

CIMI:

108316828(ACVR1C)

ANAN:

105719007(ACVR1C)

CSYR:

103254950(ACVR1C)

MMUR:

105860477(ACVR1C)

LCAT:

123643200(ACVR1C)

ERUF:

138386144(ACVR1C)

PCOQ:

105807389(ACVR1C)

OGA:	100940744(ACVR1C)

MMU:	269275(Acvr1c)

MCAL:

110286402(Acvr1c)

MPAH:

110318359(Acvr1c)

RNO:	245921(Acvr1c)

MCOC:

116090192(Acvr1c)

ANU:	117703639(Acvr1c)

ASYL:

127685377(Acvr1c)

MUN:	110549515(Acvr1c)

CGE:	100756930(Acvr1c)

MAUA:

101827659(Acvr1c)

PROB:

127222503(Acvr1c)

PLEU:

114695884(Acvr1c)

PMAV:

102914460(Acvr1c)

MORG:

121433253(Acvr1c)

MFOT:

126489422

AAMP:

119819331(Acvr1c)

CNL:	130864468(Acvr1c)

NGI:	103741051(Acvr1c)

HGL:	101712645(Acvr1c)

CPOC:

100724706(Acvr1c)

CCAN:

109688925(Acvr1c)

DORD:

105994593(Acvr1c)

DSP:	122110815(Acvr1c)

DMER:

138827350(Acvr1c)

PLOP:

125350654(Acvr1c)

NCAR:

124980962

MMMA:

107136869(Acvr1c)

ITI:	101964138(Acvr1c)

OCU:

100357061

OPI:	101528913(ACVR1C)

OCZ:	121150865(ACVR1C)

TUP:	102497450(ACVR1C)

GVR:	103603315(ACVR1C)

CFA:	488361(ACVR1C)

CLUD:

112674727(ACVR1C)

VVP:	112916492(ACVR1C)

VLG:	121471362(ACVR1C)

NPO:	129498912(ACVR1C)

AML:	100476073(ACVR1C)

UMR:	103659481(ACVR1C)

UAH:	113250865(ACVR1C)

UAR:	123781850(ACVR1C)

ELK:

111143078

LLV:

125095422

MPUF:

101683129(ACVR1C)

MNP:	132013763(ACVR1C)

MLK:	131827199(ACVR1C)

NVS:	122902510(ACVR1C)

ORO:	101362502(ACVR1C)

EJU:	114216499(ACVR1C)

ZCA:	113920584(ACVR1C)

MLX:	118012426(ACVR1C)

NSU:	110592078(ACVR1C)

LWW:	102749056(ACVR1C)

FCA:	101091037(ACVR1C)

PYU:	121030588(ACVR1C)

PCOO:

112867793(ACVR1C)

PBG:	122481353(ACVR1C)

PVIV:

125172698(ACVR1C)

LRUF:

124515803

LGF:	123598951(ACVR1C)

AJU:

106978940

PTG:	102956256(ACVR1C)

PPAD:

109271500(ACVR1C)

PUC:

125911603

PLEZ:

122226144(ACVR1C)

HHV:	120235310(ACVR1C)

BTA:	536380(ACVR1C)

BOM:	102275656(ACVR1C)

BIU:	109567491(ACVR1C)

BBUB:

102407174(ACVR1C)

BKE:	129646408(ACVR1C)

BBIS:

104988651

CHX:	102174882(ACVR1C)

OAS:	101111867(ACVR1C)

BTAX:

128062516(ACVR1C)

CSUM:

138076753(ACVR1C)

ODA:	120854820(ACVR1C)

CCAD:

122453842(ACVR1C)

MREE:

136163442(ACVR1C)

OVR:	110141504(ACVR1C)

MBEZ:

129538180(ACVR1C)

SSC:	100156756(ACVR1C)

CFR:	102511434(ACVR1C)

CBAI:

105081926(ACVR1C)

CDK:	105093708(ACVR1C)

VPC:	102535112(ACVR1C)

BACU:

102998447(ACVR1C)

BMUS:

118898108(ACVR1C)

LVE:	103084357(ACVR1C)

OOR:	101286390(ACVR1C)

LALB:

132521817(ACVR1C)

GMF:	115849008(ACVR1C)

DDP:	132428623(ACVR1C)

DLE:	111172772(ACVR1C)

PCAD:

102991643(ACVR1C)

PSIU:

116757148(ACVR1C)

PPHC:

136125554(ACVR1C)

NASI:

112393588(ACVR1C)

ECB:	100059573(ACVR1C)

EPZ:	103554404(ACVR1C)

EAI:	106841965(ACVR1C)

MYB:	102243009(ACVR1C)

MYD:	102767691(ACVR1C)

MMYO:

118661942(ACVR1C)

MLF:	102435125(ACVR1C)

MDT:	132238619(ACVR1C)

MYUM:

139015304(ACVR1C)

PKL:	118709540(ACVR1C)

EFUS:

103283392(ACVR1C)

MNA:	107527879(ACVR1C)

DRO:	112322257(ACVR1C)

SHON:

118985805(ACVR1C)

AJM:	119044110(ACVR1C)

PDIC:

114494466(ACVR1C)

PHAS:

123831176(ACVR1C)

MMF:	118625340(ACVR1C)

PPAM:

129061846(ACVR1C)

HAI:	109379832(ACVR1C)

RFQ:	117025450(ACVR1C)

PALE:

102880288(ACVR1C)

PGIG:

120596906(ACVR1C)

PVP:	105291355(ACVR1C)

RAY:	107513428(ACVR1C)

MJV:	108392567(ACVR1C)

TOD:	119255853(ACVR1C)

SARA:

101541867(ACVR1C)

SFUM:

130019751(ACVR1C)

SETR:

126008847(ACVR1C)

LAV:	100667186(ACVR1C)

TMU:

101356798

ETF:	101656476(ACVR1C)

DNM:	101438535(ACVR1C)

MDO:	100021309(ACVR1C)

GAS:	123242250(ACVR1C)

SHR:	100931037(ACVR1C)

AFZ:

127554638

PCW:	110220762(ACVR1C)

TVP:	118840289(ACVR1C)

PBRV:

138154709(ACVR1C)

MLAO:

141507867(ACVR1C)

OAA:	100081575(ACVR1C)

TACU:

119932287(ACVR1C)

GGA:	424325(ACVR1C)

PCOC:

116227300(ACVR1C)

MGP:	100548397(ACVR1C)

CJO:	107317033(ACVR1C)

TPAI:

128077003(ACVR1C)

LMUT:

125696684(ACVR1C)

NMEL:

110400254(ACVR1C)

APLA:

101794826(ACVR1C)

AACU:

137858738(ACVR1C)

ACYG:

106043916(ACVR1C)

CATA:

118257724(ACVR1C)

AFUL:

116490814(ACVR1C)

TGU:	100232553(ACVR1C)

LSR:	110477591(ACVR1C)

SCAN:

103814245(ACVR1C)

PMOA:

120497336(ACVR1C)

OTC:	121338071(ACVR1C)

PRUF:

121352808(ACVR1C)

ATRC:

139593970(ACVR1C)

GFR:	102040579(ACVR1C)

FAB:	101817282(ACVR1C)

OMA:	130255761(ACVR1C)

PHI:	102110252(ACVR1C)

PMAJ:

107207825(ACVR1C)

CCAE:

111932400(ACVR1C)

CCW:	104694115(ACVR1C)

CBRC:

103616759(ACVR1C)

ACOE:

138113258(ACVR1C)

ETL:	114070853(ACVR1C)

ZLE:	135450090(ACVR1C)

ACHL:

103809212(ACVR1C)

SVG:	106861927(ACVR1C)

MMEA:

130586940

HRT:	120755421(ACVR1C)

SATI:

136374823(ACVR1C)

CCIC:

134047470(ACVR1C)

FPG:	101912153(ACVR1C)

FCH:	102052691(ACVR1C)

CCRI:

104158235

NNT:	104407191(ACVR1C)

SHAB:

115607969(ACVR1C)

ACUN:

113482005(ACVR1C)

SURA:

141945532(ACVR1C)

TALA:

104359891(ACVR1C)

ACHC:

115342870(ACVR1C)

HLE:	104829036(ACVR1C)

AGEN:

126044131

HHAR:

128143946(ACVR1C)

BBUT:

142031518(ACVR1C)

GCL:

127018150

CSTI:

104556815

LDI:	104353220(ACVR1C)

MNB:

103781126

DPUB:

104296935(ACVR1C)

PPUS:

135187567(ACVR1C)

AVIT:

104275605(ACVR1C)

EGZ:	104126446(ACVR1C)

NNI:	104012352(ACVR1C)

PCRI:

104028077(ACVR1C)

PCAO:

104044062

PADL:

103925326(ACVR1C)

AFOR:

103893869(ACVR1C)

FGA:	104076948(ACVR1C)

CBOR:

142083339(ACVR1C)

GSTE:

104262801

CBOY:

140657311(ACVR1C)

MAME:

142414572(ACVR1C)

CLV:	102086761(ACVR1C)

CNIC:

135990570(ACVR1C)

MUI:	104544343(ACVR1C)

PGUU:

104463664(ACVR1C)

EHS:

104516446

CMAC:

104476017(ACVR1C)

CUCA:

104056185(ACVR1C)

TEO:	104383818(ACVR1C)

BREG:

104634332

GAME:

129207943(ACVR1C)

OHA:	104327293(ACVR1C)

ACAR:

104523277

CPEA:

104391747

CVF:	104286819(ACVR1C)

RTD:	128912991(ACVR1C)

CRID:

134518575(ACVR1C)

LMIC:

141746579(ACVR1C)

NARQ:

141463336(ACVR1C)

AAM:	106486546(ACVR1C)

AROW:

112962280(ACVR1C)

NPD:	112946356(ACVR1C)

TGT:	104572346(ACVR1C)

DNE:	112988333(ACVR1C)

SCAM:

104138754(ACVR1C)

AMJ:	106736618(ACVR1C)

CPOO:

109323227(ACVR1C)

GGN:	109301297(ACVR1C)

PSS:	102455070(ACVR1C)

CIZ:	142016844(ACVR1C)

CMY:	102929309(ACVR1C)

LKP:	140895557(ACVR1C)

NDS:	141995889(ACVR1C)

DCC:	119863714(ACVR1C)

CPIC:

101938391(ACVR1C)

TST:	117885215(ACVR1C)

CABI:

116830036(ACVR1C)

MRV:	120374602(ACVR1C)

ACS:	100552477(acvr1c)

ASAO:

132776061(ACVR1C)

PVT:	110083042(ACVR1C)

SUND:

121928505(ACVR1C)

PBI:	103048675(ACVR1C)

PMUR:

107289585(ACVR1C)

CTIG:

120304605(ACVR1C)

PGUT:

117670381(ACVR1C)

PCAE:

139327226(ACVR1C)

APRI:

131202876(ACVR1C)

PTEX:

113434144(ACVR1C)

NSS:	113416518 113416573

VKO:	123017183(ACVR1C)

PMUA:

114605242(ACVR1C)

PRAF:

128422829(ACVR1C)

ZVI:	118093089(ACVR1C)

HCG:	128329154(ACVR1C)

GJA:	107110745(ACVR1C)

STOW:

125427404(ACVR1C)

EMC:	129324051(ACVR1C)

XLA:	108701335(acvr1c.L) 108702964(acvr1c.S)

XTR:	100487548(acvr1c)

NPR:	108784357(ACVR1C)

RTEM:

120944094(ACVR1C)

ACAT:

141147071(ACVR1C)

PADS:

140335519(ACVR1C)

BBUF:

121007673(ACVR1C)

BGAR:

122944784(ACVR1C)

DTC:	141049334(ACVR1C)

PWL:	138285342(ACVR1C)

MUO:	115474060(ACVR1C)

GSH:	117361088(ACVR1C)

DRE:	100331105(acvr1c)

SRX:	107734493 107745259

SANH:

107657408 107685426

SGH:	107548804 107567976

CCAR:

CAUA:

CGIB:

LROH:

GRF:	141341193(acvr1c)

OMC:

PPRM:

RKG:

MAMB:

CIDE:

CERY:

MASI:

TROS:

TDW:

MANU:

129451559(acvr1c)

PDAB:

135758555(acvr1c)

IPU:

108266932

IFU:

128609088

PHYP:

113525889(acvr1c)

SMEO:

TFD:

TVC:

CGAR:

NGRA:

TRN:

AMEX:

CMAO:

EEE:	113574646(acvr1c)

CHAR:

105902685

SPIL:

134078248

ASAD:

121687999

TRU:	101078818(acvr1c)

TFS:

130525765

TNG:	GSTEN00030563G001

LCO:	104920074(acvr1c)

NCC:	104954402(acvr1c)

TBEN:

117485732

CGOB:

115026287(acvr1c)

PGEO:

GACU:

EMAC:

ELY:

EFO:

PLEP:

SLUC:

ECRA:

ESP:	116698209(acvr1c)

PFLV:

114563656(acvr1c)

GAT:

PPUG:

AFB:

CLUM:

PSWI:

CANA:

CVE:

MSAM:

SCHU:

EARM:

CUD:

SPUL:

LMIX:

HTC:	141808679(acvr1c)

ALAT:

119026275

ASTR:

137605366

PKLU:

139208757

MZE:	101474023(acvr1c)

ONL:	100706478(acvr1c)

OAU:

116322906

OLA:	101173751(acvr1c)

OML:

112154726

CSAI:

133445987

XMA:	102235320(acvr1c)

XCO:	114147496(acvr1c)

XHE:	116722531(acvr1c)

PRET:

103461684(acvr1c)

PFOR:

103150582(acvr1c)

PLAI:

106946919(acvr1c)

PMEI:

106923782(acvr1c)

GAF:	122840029 122840034

PPRL:

129361222

CVG:	107087126(acvr1c)

CTUL:

119783868

GMU:

124870923

NFU:	107390087(acvr1c)

KMR:

108240717

ALIM:

106523311(acvr1c)

NWH:

AOCE:

EJA:

BFRE:

MCEP:

CSEM:

103392172(acvr1c)

POV:	109631050(acvr1c)

SSEN:

SSOE:

HHIP:

HSP:

PPLT:

SMAU:

LCF:

SDU:	111218255(acvr1c)

SLAL:

111651261(acvr1c)

XGL:

120801411

HCQ:	109514810(acvr1c)

SSCV:

SBIA:

PEE:

PTAO:

BPEC:

110166533(acvr1c)

ENY:	140359434(acvr1c)

MALB:

109957121(acvr1c)

BSPL:

SJO:

SSCO:

TTY:

GMH:	115533576(acvr1c)

SASA:

106581819(acvr1c) 106586171

STRU:

115156084(acvr1c) 115160699

OTW:	112225175 112234148

OMY:	110501520 110520051

OGO:	124042148 124043818

ONE:	115108347 115141085(acvr1c)

OKI:	109865965 109870989

OKE:	118367128 118385985

OMM:	135519641 135547164

OCLA:

139380313 139397182

SALP:

111959349(acvr1c) 111974507

SNH:	120058226 120064022

SFON:

129816337 129821332

CCLU:

121536271 121551790

ELS:	105022430(acvr1c)

OEP:

134017894

SFM:	108927962(acvr1c) 108928917

PKI:	111835935 111858375

AANG:

118214622 118222316

AROT:

135240679 135250744

CCOG:

133116367 133123742

LOC:	102691429(acvr1c)

PSPA:

121322436 121323389

ARUT:

117411948 117426977

PSEX:

120531752

LCM:	102367134(ACVR1C)

CPLA:

HOC:

HAKA:

PMRN:

DFR:

Reference

PMID:12063393

Authors

Bondestam J, Huotari MA, Moren A, Ustinov J, Kaivo-Oja N, Kallio J, Horelli-Kuitunen N, Aaltonen J, Fujii M, Moustakas A, Ten Dijke P, Otonkoski T, Ritvos O

Title

cDNA cloning, expression studies and chromosome mapping of human type I serine/threonine kinase receptor ALK7 (ACVR1C).

Journal

Cytogenet Cell Genet 95:157-62 (2001)
DOI:10.1159/000059339

Sequence

[hsa:130399]

LinkDB

ORTHOLOGY: K04670

Entry

K04670                      KO

Symbol

ACVR2A

Name

activin receptor type-2A [EC:2.7.11.30]

Pathway

map04060

Cytokine-cytokine receptor interaction

map04350

TGF-beta signaling pathway

map04550

Signaling pathways regulating pluripotency of stem cells

map05418

Fluid shear stress and atherosclerosis

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04350 TGF-beta signaling pathway
    K04670  ACVR2A; activin receptor type-2A
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K04670  ACVR2A; activin receptor type-2A
09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    K04670  ACVR2A; activin receptor type-2A
09160 Human Diseases
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    K04670  ACVR2A; activin receptor type-2A
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K04670  ACVR2A; activin receptor type-2A
Enzymes [BR:ko01000]
2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.30  receptor protein serine/threonine kinase
     K04670  ACVR2A; activin receptor type-2A
Protein kinases [BR:ko01001]
Receptor serine/threonine kinases (RSTK): TKL group
  TGFBR2 family [OT]
   K04670  ACVR2A; activin receptor type-2A

Other DBs

GO:

0016362

Genes

HSA:	92(ACVR2A)

PTR:	459646(ACVR2A)

PPS:	100978909(ACVR2A)

GGO:	101126947(ACVR2A)

PON:	100435220(ACVR2A)

PPYG:

129031481(ACVR2A)

NLE:	100583170(ACVR2A)

HMH:	116462882(ACVR2A)

SSYN:

129471879(ACVR2A)

MCC:	707017(ACVR2A)

MCF:	102121129(ACVR2A)

MTHB:

126932908

MNI:	105492701(ACVR2A)

CSAB:

103217052(ACVR2A)

CATY:

105575953(ACVR2A)

PANU:

101009691(ACVR2A)

TGE:	112635816(ACVR2A)

MLEU:

105531383(ACVR2A)

RRO:	104655489(ACVR2A)

RBB:	108512386(ACVR2A)

TFN:	117095028(ACVR2A)

PTEH:

111546133(ACVR2A)

CANG:

105512596(ACVR2A)

CJC:	100397767(ACVR2A)

SBQ:	101036787(ACVR2A)

CIMI:

108300366(ACVR2A)

ANAN:

105720520(ACVR2A)

CSYR:

103262246(ACVR2A)

MMUR:

105860222(ACVR2A)

LCAT:

123643301(ACVR2A)

ERUF:

138374850(ACVR2A)

PCOQ:

105822230(ACVR2A)

OGA:	100943776(ACVR2A)

MMU:	11480(Acvr2a)

MCAL:

110309902(Acvr2a)

MPAH:

110318164(Acvr2a)

RNO:	29263(Acvr2a)

MCOC:

116090146(Acvr2a)

ANU:	117703021(Acvr2a)

ASYL:

127685346(Acvr2a)

MUN:	110539455(Acvr2a)

CGE:	100774605(Acvr2a)

MAUA:

101842415(Acvr2a)

PROB:

127222541(Acvr2a)

PLEU:

114700439(Acvr2a)

PMAV:

102907294(Acvr2a)

MORG:

121433139(Acvr2a)

MFOT:

126500227

AAMP:

119818383(Acvr2a)

CNL:	130864293(Acvr2a)

NGI:	103727329(Acvr2a)

HGL:	101707586(Acvr2a)

CPOC:

100731791(Acvr2a)

CCAN:

109689204(Acvr2a)

DORD:

105996506(Acvr2a)

DSP:	122110790(Acvr2a)

DMER:

138828005(Acvr2a)

PLOP:

125350695(Acvr2a)

NCAR:

124981189

MMMA:

107136837(Acvr2a)

ITI:	101975721(Acvr2a)

OCU:

100008631

OPI:	101536630(ACVR2A)

OCZ:	121150587(ACVR2A)

TUP:	102499226(ACVR2A)

GVR:	103592000(ACVR2A)

CFA:	476140(ACVR2A)

CLUD:

112649428(ACVR2A)

VVP:	112926859(ACVR2A)

VLG:	121482017(ACVR2A)

NPO:	129495412 129514449

AML:	100472026(ACVR2A)

UMR:	103667704(ACVR2A)

UAH:	113250906(ACVR2A)

UAR:	123782213(ACVR2A)

ELK:

111145945

LLV:

125095863

MPUF:

101685213(ACVR2A)

MNP:	132013902(ACVR2A)

MLK:	131826989(ACVR2A)

NVS:	122902672(ACVR2A)

ORO:	101369734(ACVR2A)

EJU:	114224562(ACVR2A)

ZCA:	113919393(ACVR2A)

MLX:	118012466(ACVR2A)

NSU:	110591839(ACVR2A)

LWW:	102726739(ACVR2A)

FCA:	101097750(ACVR2A)

PYU:	121030536(ACVR2A)

PCOO:

112871725(ACVR2A)

PBG:	122481313(ACVR2A)

PVIV:

125172951(ACVR2A)

LRUF:

124516063

LGF:	123598907(ACVR2A)

AJU:

106971526

PTG:	102948807(ACVR2A)

PPAD:

109270733(ACVR2A)

PUC:

125911887

PLEZ:

122226099(ACVR2A)

HHV:	120240004(ACVR2A)

BTA:	281598(ACVR2A)

BOM:	102269861(ACVR2A)

BIU:	109567962(ACVR2A)

BBUB:

102408304(ACVR2A)

BKE:	129646451(ACVR2A)

BBIS:

104988599(ACVR2A)

CHX:	100860918(ACVR2A)

OAS:	443304(ACVR2A)

BTAX:

128069136(ACVR2A)

CSUM:

138075574(ACVR2A)

ODA:	120854769(ACVR2A)

CCAD:

122453864(ACVR2A)

MREE:

136165292(ACVR2A)

OVR:	110129028(ACVR2A)

MBEZ:

129538665(ACVR2A)

SSC:	397282(ACVR2A)

CFR:	102518044(ACVR2A)

CBAI:

105065196(ACVR2A)

CDK:	105084601(ACVR2A)

VPC:	102524712(ACVR2A)

BACU:

103002388(ACVR2A)

BMUS:

118897886(ACVR2A)

LVE:	103079492(ACVR2A)

OOR:	101283151(ACVR2A)

LALB:

132522392(ACVR2A)

GMF:	115849179(ACVR2A)

DDP:	132428652(ACVR2A)

DLE:	111172738(ACVR2A)

PCAD:

102976118(ACVR2A)

PSIU:

116756664(ACVR2A)

PPHC:

136126012(ACVR2A)

NASI:

112399108(ACVR2A)

ECB:	100049823(ACVR2A)

EPZ:	103549990(ACVR2A)

EAI:	106825091(ACVR2A)

MYB:	102253638(ACVR2A)

MYD:	102768276(ACVR2A)

MMYO:

118662002(ACVR2A)

MLF:	102440476(ACVR2A)

MDT:	132238657(ACVR2A)

MYUM:

139015335(ACVR2A)

PKL:	118709272(ACVR2A)

EFUS:

103283424(ACVR2A)

MNA:	107531463(ACVR2A)

DRO:	112313101(ACVR2A)

SHON:

118974389(ACVR2A)

AJM:	119065590(ACVR2A)

PDIC:

114495284(ACVR2A)

PHAS:

123813825(ACVR2A)

MMF:	118625581(ACVR2A)

PPAM:

129061744(ACVR2A)

HAI:	109388998(ACVR2A)

RFQ:	117025927(ACVR2A)

PALE:

102891559(ACVR2A)

PGIG:

120597054(ACVR2A)

PVP:	105291730(ACVR2A)

RAY:	107513936(ACVR2A)

MJV:	108391910(ACVR2A)

TOD:	119255811(ACVR2A)

SARA:

101555829(ACVR2A)

SFUM:

130026873(ACVR2A)

SETR:

126008764(ACVR2A)

LAV:	100672302(ACVR2A)

TMU:

101346907

ETF:	101641411(ACVR2A)

DNM:	101438319(ACVR2A)

MDO:	100018756(ACVR2A)

GAS:	123242271(ACVR2A)

SHR:	100918537(ACVR2A)

AFZ:

127554382

PCW:	110207162(ACVR2A)

TVP:	118837833(ACVR2A)

PBRV:

138145086(ACVR2A)

MLAO:

141507462(ACVR2A)

OAA:	100089503(ACVR2A)

TACU:

119932182(ACVR2A)

GGA:	396324(ACVR2A)

PCOC:

116227445(ACVR2A)

MGP:	100545173(ACVR2A)

CJO:	107317053(ACVR2A)

TPAI:

128077078(ACVR2A)

LMUT:

125697207(ACVR2A)

NMEL:

110399402(ACVR2A)

APLA:

101789784(ACVR2A)

AACU:

137858785(ACVR2A)

ACYG:

106041002(ACVR2A)

CATA:

118252577(ACVR2A)

AFUL:

116490812(ACVR2A)

TGU:	100224301(ACVR2A)

LSR:	110476487(ACVR2A)

SCAN:

103814260(ACVR2A)

PMOA:

120503401(ACVR2A)

OTC:	121335608(ACVR2A)

PRUF:

121356446(ACVR2A)

ATRC:

139593936(ACVR2A)

GFR:	102039219(ACVR2A)

FAB:	101821260(ACVR2A)

OMA:	130255799(ACVR2A)

PHI:	102113171(ACVR2A)

PMAJ:

107207587(ACVR2A)

CCAE:

111932342(ACVR2A)

CCW:	104694095(ACVR2A)

CBRC:

103616770(ACVR2A)

ACOE:

138113230(ACVR2A)

ETL:	114070947(ACVR2A)

ZAB:	102073262(ACVR2A)

ZLE:	135450460(ACVR2A)

SVG:	106849883(ACVR2A)

MMEA:

130582991(ACVR2A)

HRT:	120755507(ACVR2A)

SATI:

136363732(ACVR2A)

CFAI:

136293538(ACVR2A)

CCIC:

134047164(ACVR2A)

FPG:	101915701(ACVR2A)

FCH:	102053325(ACVR2A)

CCRI:

104168653(ACVR2A)

NNT:	104408661(ACVR2A)

SHAB:

115608311(ACVR2A)

ACUN:

113481999(ACVR2A)

SURA:

141945502(ACVR2A)

TALA:

104359780(ACVR2A)

ACHC:

115342594(ACVR2A)

HALD:

104315854(ACVR2A)

HLE:	104836541(ACVR2A)

AGEN:

126044910

HHAR:

128143944(ACVR2A)

BBUT:

142031484(ACVR2A)

GCL:

127018204

CSTI:

104550395(ACVR2A)

LDI:	104346166(ACVR2A)

MNB:	103779561(ACVR2A)

DPUB:

104308269(ACVR2A)

PPUS:

135181465(ACVR2A)

AVIT:

104272637 104274910(ACVR2A)

BRHI:

104498027(ACVR2A)

EGZ:	104130385(ACVR2A)

NNI:	104009770(ACVR2A)

PCRI:

104025271(ACVR2A)

PCAO:

104048292(ACVR2A)

PADL:

103912640(ACVR2A)

AFOR:

103903938(ACVR2A)

FGA:	104083027(ACVR2A)

CBOR:

142083368(ACVR2A)

GSTE:

104255206(ACVR2A)

CBOY:

140657774(ACVR2A)

MAME:

142414727(ACVR2A)

CLV:	102098638(ACVR2A)

CNIC:

135990338(ACVR2A)

MUI:	104548931(ACVR2A)

PGUU:

104462896(ACVR2A)

PLET:

104625396(ACVR2A)

EHS:	104505914(ACVR2A)

CMAC:

104482580(ACVR2A)

CUCA:

104057544(ACVR2A)

TEO:	104372713(ACVR2A)

BREG:

104641234

GAME:

129207960(ACVR2A)

OHA:	104331754(ACVR2A)

ACAR:

104531704(ACVR2A)

CPEA:

104395849(ACVR2A)

CVF:	104287627(ACVR2A)

RTD:	128912250(ACVR2A)

CRID:

134518217(ACVR2A)

LMIC:

141746191(ACVR2A)

NARQ:

141462962(ACVR2A)

AAM:	106498516(ACVR2A)

AROW:

112977075(ACVR2A)

NPD:	112948612(ACVR2A)

TGT:

104577773

DNE:	112981726(ACVR2A)

SCAM:

104145692(ACVR2A)

ASN:	102368733(ACVR2A)

AMJ:	102562921(ACVR2A)

CPOO:

109322767(ACVR2A)

GGN:	109301328(ACVR2A)

PSS:	102454507(ACVR2A)

CIZ:	142017246(ACVR2A)

CMY:	102945188(ACVR2A)

CCAY:

125645134(ACVR2A)

LKP:	140895530(ACVR2A)

NDS:	141995861(ACVR2A)

DCC:	119863213(ACVR2A)

CPIC:

101933615(ACVR2A)

TST:	117884643(ACVR2A)

CABI:

116831627(ACVR2A)

MRV:	120374534(ACVR2A)

ACS:	100562173(acvr2a)

ASAO:

132775577(ACVR2A)

PVT:	110074952(ACVR2A)

SUND:

121919301(ACVR2A)

PBI:	103055188(ACVR2A)

PMUR:

107294303(ACVR2A)

CTIG:

120301136(ACVR2A)

TSR:	106545601(ACVR2A)

PGUT:

117669944(ACVR2A)

PCAE:

139318059(ACVR2A)

APRI:

131203250(ACVR2A)

PTEX:

113434170(ACVR2A)

NSS:	113415905(ACVR2A)

VKO:	123027299(ACVR2A)

PMUA:

114604932(ACVR2A)

PRAF:

128422357(ACVR2A)

ZVI:	118092702(ACVR2A)

HCG:	128330595(ACVR2A)

GJA:	107108802(ACVR2A)

STOW:

125426767(ACVR2A)

EMC:	129324054(ACVR2A)

XLA:	399283(acvr2a.L) 495087(acvr2a.S)

XTR:	100216172(acvr2a)

NPR:	108795499(ACVR2A)

RTEM:

120944125(ACVR2A)

ACAT:

141147111(ACVR2A)

PADS:

140335490(ACVR2A)

BBUF:

121008845(ACVR2A)

BGAR:

122944589(ACVR2A)

DTC:	141049298(ACVR2A)

PWL:	138285380(ACVR2A)

MUO:	115473769(ACVR2A)

GSH:	117360939(ACVR2A)

DRE:	100331014(acvr2ab) 553359(acvr2aa)

SRX:	107705816 107705898 107709421 107724023

SANH:

107666699 107673126 107675352 107691069

SGH:	107555835 107572302 107582301 107601072

CCAR:

109056978(acvr2aa) 109102232

CAUA:

113051000 113053255 113089469 113108715

CGIB:

127959989 127964857 128015280 128019816

PTET:

122333282(acvr2ab) 122351491(acvr2aa)

LROH:

127167413(acvr2ab) 127170616(acvr2aa)

GRF:	141340341(acvr2aa) 141346384 141346625(acvr2ab)

OMC:	131542687(acvr2ab) 131546598(acvr2aa)

PPRM:

120466776(acvr2aa) 120467934(acvr2ab)

RKG:	130078533(acvr2ab) 130085952(acvr2aa)

MAMB:

125270224(acvr2aa) 125274472

CIDE:

127514861 127518488

CERY:

137010811(acvr2ab) 137036515(acvr2aa)

MASI:

127446199 127446906 127448384 127449057

TROS:

130555845(acvr2aa) 130556443(acvr2ab)

TDW:	130424512(acvr2ab) 130427364(acvr2aa)

MANU:

129450435(acvr2ab) 129451491(acvr2aa)

PDAB:

135733221(acvr2aa) 135783241(acvr2ab)

IPU:	108266626(acvr2aa) 108272703

IFU:	128608617(acvr2aa) 128615392

PHYP:

113535046 113538182

SMEO:

124382650(acvr2aa) 124389249(acvr2ab)

TFD:	113646266(acvr2aa) 113651132(acvr2ab)

TVC:	132844918(acvr2ab) 132849823(acvr2aa)

CGAR:

128524059(acvr2aa) 128526510(acvr2ab)

NGRA:

132884822(acvr2ab) 132891559(acvr2aa)

TRN:	134317090(acvr2ab) 134323986(acvr2aa)

AMEX:

103032572(acvr2aa) 103040899(acvr2ab)

CMAO:

118807865(acvr2ab) 118808510(acvr2aa)

EEE:	113581626(acvr2a) 113588617

CHAR:

105893095(acvr2aa) 105901787(acvr2ab)

SPIL:

134070894 134078459(acvr2aa)

ASAD:

121693950(acvr2aa) 121698858

TRU:	101067920(acvr2a) 101071858

TFS:	130522848 130536732(acvr2aa)

LCO:	104926240(acvr2a) 104935816

NCC:	104960238(acvr2a)

TBEN:

117486205

CGOB:

115018276(acvr2a)

PGEO:

117457566

GACU:

117539281

EMAC:

134860794 134867309(acvr2aa)

ELY:	117250046 117251307(acvr2aa)

EFO:	125884886 125899797(acvr2aa)

PLEP:

121948851 121963066

SLUC:

116048622(acvr2ab) 116064172(acvr2aa)

ECRA:

117939485(acvr2ab) 117953066

ESP:	116674031(acvr2a) 116679314

PFLV:

114550865(acvr2a) 114563875

GAT:	120815576(acvr2ab)

PPUG:

119212689 119228726

AFB:	129104573 129111556

CLUM:

117740968 117750290(acvr2aa)

PSWI:

130204385 130206978(acvr2aa)

CANA:

137793873 137803228(acvr2aa)

CVE:	137879196 137891431(acvr2aa)

MSAM:

119903741(acvr2aa) 119905275(acvr2ab)

SCHU:

122872371 122885386(acvr2aa)

EARM:

139292031(acvr2aa) 139306472

CUD:	121506438(acvr2ab) 121522379

SPUL:

138592284(acvr2aa) 138603379

LMIX:

132959800 132987204(acvr2aa)

HTC:	141785783(acvr2ab) 141808277

ALAT:

119015236 119025671(acvr2aa)

ASTR:

137591176 137604676(acvr2aa)

PKLU:

139208926(acvr2aa) 139223551

MZE:	101464704 101481875(acvr2a)

ONL:	100694010 100709514

OAU:	116316406(acvr2ab) 116316813(acvr2aa)

OLA:	100049489(acvr2a)

OML:

112156615

CSAI:

133425416(acvr2ab)

XMA:	102217256 102227541(acvr2a)

XCO:	114141013(acvr2a) 114147517

XHE:	116715774(acvr2a) 116723094

PRET:

103457427(acvr2a) 103460036

PFOR:

103149472(acvr2a) 103152084

PLAI:

106936383(acvr2a) 106963634

PMEI:

106905709(acvr2a) 106931128

GAF:	122826996(acvr2ab) 122840146(acvr2aa)

PPRL:

129353448(acvr2ab) 129374564(acvr2aa)

CVG:	107082824(acvr2a) 107091036

CTUL:

119794423 119798385

GMU:	124861389 124871236

NFU:	107384683(acvr2a)

KMR:	108245115 108250825(acvr2aa)

ALIM:

106535166(acvr2a)

NWH:

119428750

AOCE:

111563996 111581847(acvr2aa)

EJA:	138201199(acvr2aa) 138207070

BFRE:

138620806

MCEP:

125000655 125018199

CSEM:

103389624(acvr2a)

POV:	109639027(acvr2a) 109642017

SSEN:

122784346

SSOE:

131443610

HHIP:

117754867(acvr2aa) 117776118

HSP:	118103478 118119824(acvr2aa)

PPLT:

128431253(acvr2ab) 128455749

SMAU:

118282891 118312297(acvr2ab)

LCF:	108873081 108874503(acvr2aa) 108888565

SDU:	111230419 111233326(acvr2a)

SLAL:

111656765 111670353(acvr2a)

XGL:	120798097 120801179(acvr2aa)

HCQ:	109528490(acvr2a)

SSCV:

SBIA:

PEE:

PTAO:

BPEC:

110153188(acvr2a)

ENY:

140362506

MALB:

109955601(acvr2a) 109970419

BSPL:

114845792(acvr2ab) 114846906

SJO:	128353996 128367618(acvr2aa)

SSCO:

133993030(acvr2aa)

TTY:	137177054 137192203(acvr2aa)

GMH:	115532713(acvr2a) 115541940

SASA:

106574301 106575234 106582410 106586327

STRU:

115155533 115160846 115179829 115195962

OTW:	112225629 112237546 112253978 112266566

OMY:	110495930 110501883 110520186(acvr2aa) 110527542

OGO:	124008116 124010571 124043937(acvr2aa) 124048601

ONE:	115109988 115129641 115130367 115134071

OKI:	109867401 109870874 109890681 109906676

OKE:	118363694 118366991 118370160 118386387

OMM:	135519397 135542491 135547653

OCLA:

139373260 139380916 139399688 139413085

SALP:

111953286 111959585 111970997 111976339

SNH:	120033424 120051243 120058299 120064143

SFON:

129816665 129821189 129840676 129859543

CCLU:

121536712 121555172 121562507 123486065

ELS:	105016248 105022549

OEP:	134007452(acvr2ab) 134017530(acvr2aa)

SFM:	108924278 108929958(acvr2a)

PKI:	111846093 111849470

AANG:

118214263 118223535

AROT:

135240475 135250424

CCOG:

133116444 133123787

LOC:	102685062(acvr2a)

PSPA:

121322327 121322905

ARUT:

117410738 117427134

PSEX:

120531704

LCM:	102354804(ACVR2A)

CMK:

103180467

RTP:

109912424

CPLA:

122551736

CPUN:

140482372(acvr2aa)

HOC:

SCAU:

STOZ:

LERI:

HAKA:

140714639(acvr2aa)

BBEL:

SPU:

LPIC:

LVG:

AJJ:

ARUN:

AAMU:

RZE:

FAS:

DAM:

AGIF:

SOY:

AGRG:

CSET:

AGB:

LDC:

APLN:

PPYR:

OTU:

CCRN:

DCI:

HHAL:

106684227(put)

MQU:

FOC:

TPAL:

SGRE:

DMK:

DPZ:

PJA:

PCHN:

HAME:

PCLA:

PTRU:

ESN:

HAZT:

TCF:

VDE:

VJA:

GOE:

BGT:

CVN:	111126321 111128797

MCAF:

MMER:

RPHI:

DPOL:

MAEA:

NVE:

ATEN:

SPIS:

DGT:

XEN:

HMG:

HSY:

RES:

Reference

PMID:1311955

Authors

Matzuk MM, Bradley A

Title

Cloning of the human activin receptor cDNA reveals high evolutionary conservation.

Journal

Biochim Biophys Acta 1130:105-8 (1992)
DOI:10.1016/0167-4781(92)90472-C

Sequence

[hsa:92]

LinkDB

ORTHOLOGY: K13596

Entry

K13596                      KO

Symbol

ACVR2B

Name

activin receptor type-2B [EC:2.7.11.30]

Pathway

map04060

Cytokine-cytokine receptor interaction

map04350

TGF-beta signaling pathway

map04550

Signaling pathways regulating pluripotency of stem cells

map05418

Fluid shear stress and atherosclerosis

Disease

H00632

Heterotaxy

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04350 TGF-beta signaling pathway
    K13596  ACVR2B; activin receptor type-2B
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K13596  ACVR2B; activin receptor type-2B
09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    K13596  ACVR2B; activin receptor type-2B
09160 Human Diseases
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    K13596  ACVR2B; activin receptor type-2B
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K13596  ACVR2B; activin receptor type-2B
Enzymes [BR:ko01000]
2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.30  receptor protein serine/threonine kinase
     K13596  ACVR2B; activin receptor type-2B
Protein kinases [BR:ko01001]
Receptor serine/threonine kinases (RSTK): TKL group
  TGFBR2 family [OT]
   K13596  ACVR2B; activin receptor type-2B

Other DBs

GO:

0016362

Genes

HSA:	93(ACVR2B)

PTR:	460271(ACVR2B)

PPS:	100993873(ACVR2B)

GGO:	101153315(ACVR2B)

PON:	100456564(ACVR2B)

PPYG:

129032706(ACVR2B)

NLE:	100600099(ACVR2B)

HMH:	116473656(ACVR2B)

SSYN:

129484476(ACVR2B)

MCC:	696071(ACVR2B)

MCF:	102118668(ACVR2B)

MTHB:

126947575

MNI:	105480207(ACVR2B)

CSAB:

103221056(ACVR2B)

CATY:

105573896(ACVR2B)

PANU:

101004271(ACVR2B)

TGE:	112618906(ACVR2B)

MLEU:

105553438(ACVR2B)

RRO:	104668728(ACVR2B)

RBB:	108513788(ACVR2B)

TFN:	117083894(ACVR2B)

PTEH:

111555509(ACVR2B)

CANG:

105519880(ACVR2B)

CJC:	100389244(ACVR2B)

SBQ:	101037065(ACVR2B)

CIMI:

108289100(ACVR2B)

ANAN:

105719522(ACVR2B)

CSYR:

103255242

MMUR:

105866814(ACVR2B)

LCAT:

123641162(ACVR2B)

ERUF:

138386777(ACVR2B)

PCOQ:

105813950(ACVR2B)

OGA:	100957028(ACVR2B)

MMU:	11481(Acvr2b)

MCAL:

110301729(Acvr2b)

MPAH:

110327239(Acvr2b)

RNO:	25366(Acvr2b)

MCOC:

116073020(Acvr2b)

ANU:	117693679(Acvr2b)

ASYL:

127688407(Acvr2b)

MUN:	110555057(Acvr2b)

CGE:	100755103(Acvr2b)

MAUA:

101827873(Acvr2b)

PROB:

127235130(Acvr2b)

PLEU:

114682495(Acvr2b)

PMAV:

102925612(Acvr2b)

MORG:

121464277(Acvr2b)

MFOT:

126501184

AAMP:

119809769(Acvr2b)

CNL:	130872858(Acvr2b)

NGI:	103744664(Acvr2b)

HGL:	101711703(Acvr2b)

CPOC:

100722791(Acvr2b)

CCAN:

109695728(Acvr2b)

DORD:

105996238(Acvr2b)

DSP:	122096745(Acvr2b)

PLOP:

125342448(Acvr2b)

NCAR:

124968737

MMMA:

107145492(Acvr2b)

ITI:	101974329(Acvr2b)

OCU:

103347244

OPI:	101535616(ACVR2B)

OCZ:	121146232(ACVR2B)

TUP:	102468744(ACVR2B)

GVR:	103586041(ACVR2B)

CFA:	485590(ACVR2B)

CLUD:

112668751(ACVR2B)

VVP:	112921650(ACVR2B)

VLG:	121478737(ACVR2B)

NPO:	129507177(ACVR2B)

AML:	100477787(ACVR2B)

UMR:	103680677(ACVR2B)

UAH:	113253788(ACVR2B)

UAR:	123792830(ACVR2B)

ELK:

111159108

LLV:

125106374

MPUF:

101682800(ACVR2B)

MNP:	132011654(ACVR2B)

MLK:	131824361(ACVR2B)

NVS:	122909075(ACVR2B)

ORO:	101362273(ACVR2B)

EJU:	114212328(ACVR2B)

ZCA:	113917820(ACVR2B)

MLX:	118001989(ACVR2B)

NSU:	110594331(ACVR2B)

LWW:	102740977(ACVR2B)

FCA:	101086087(ACVR2B)

PYU:	121033470(ACVR2B)

PCOO:

112850074(ACVR2B)

PBG:	122492148(ACVR2B)

PVIV:

125174809(ACVR2B)

LRUF:

124526560

LGF:	123575800(ACVR2B)

AJU:

106966697

PTG:	102950575(ACVR2B)

PPAD:

109248759(ACVR2B)

PUC:

125921427

PLEZ:

122229459(ACVR2B)

HHV:	120235094(ACVR2B)

BTA:	282131(ACVR2B)

BOM:	102281557(ACVR2B)

BIU:	109576299(ACVR2B)

BBUB:

102405937(ACVR2B)

BKE:	129635518(ACVR2B)

BBIS:

104985363(ACVR2B)

CHX:	102176275(ACVR2B)

OAS:	443156(ACVR2B)

BTAX:

128047636(ACVR2B)

CSUM:

138087221(ACVR2B)

ODA:	120867651(ACVR2B)

CCAD:

122424487(ACVR2B)

MREE:

136166575(ACVR2B)

OVR:	110139832(ACVR2B)

MBEZ:

129548139(ACVR2B)

SSC:	448845(ACVR2B)

CFR:	102514517(ACVR2B)

CBAI:

105061733(ACVR2B)

CDK:	105090688(ACVR2B)

VPC:	102539874(ACVR2B)

BACU:

103009284(ACVR2B)

BMUS:

118903018(ACVR2B)

LVE:	103087212(ACVR2B)

OOR:	101277282(ACVR2B)

LALB:

132527144(ACVR2B)

GMF:	115838909(ACVR2B)

DDP:	132432163(ACVR2B)

DLE:	111164260(ACVR2B)

PCAD:

102991507(ACVR2B)

PSIU:

116761787(ACVR2B)

PPHC:

136130048(ACVR2B)

NASI:

112407198(ACVR2B)

ECB:	100053588(ACVR2B)

EPZ:	103561072(ACVR2B)

EAI:	106842858(ACVR2B)

MYB:	102246825(ACVR2B)

MYD:	102759199(ACVR2B)

MMYO:

118668348(ACVR2B)

MLF:	102424748(ACVR2B)

MDT:	132215718(ACVR2B)

MYUM:

138992330(ACVR2B)

PKL:	118715493(ACVR2B)

EFUS:

103300309(ACVR2B)

MNA:	107524303(ACVR2B)

DRO:	112309858(ACVR2B)

SHON:

118976235(ACVR2B)

AJM:	119051549(ACVR2B)

PDIC:

114501543(ACVR2B)

PHAS:

123830652(ACVR2B)

MMF:	118633239(ACVR2B)

PPAM:

129088338(ACVR2B)

HAI:	109393492(ACVR2B)

RFQ:	117037311(ACVR2B)

PALE:

102894735(ACVR2B)

PGIG:

120586741(ACVR2B)

PVP:	105288777(ACVR2B)

RAY:	107499637(ACVR2B)

MJV:	108388382(ACVR2B)

TOD:	119258110(ACVR2B)

SARA:

101543926(ACVR2B)

SFUM:

130037379(ACVR2B)

SETR:

125998137(ACVR2B)

LAV:	100658031(ACVR2B)

TMU:

101340552

ETF:	101662149(ACVR2B)

DNM:	101424622(ACVR2B)

MDO:	100029516(ACVR2B)

GAS:	123242809(ACVR2B)

SHR:	100933894(ACVR2B)

AFZ:

127553337

PCW:	110204984(ACVR2B)

TVP:	118831412(ACVR2B)

PBRV:

138157945(ACVR2B)

MLAO:

141496134(ACVR2B)

OAA:	100086400(ACVR2B)

TACU:

119936219(ACVR2B)

GGA:	374213(ACVR2B)

PCOC:

116238223(ACVR2B)

MGP:	100544085(ACVR2B)

CJO:	107308862(ACVR2B)

TPAI:

128085557(ACVR2B)

LMUT:

125696176(ACVR2B)

NMEL:

110395027(ACVR2B)

APLA:

101791121 119715822

AACU:

137852082(ACVR2B)

ACYG:

106036804(ACVR2B)

CATA:

118251799(ACVR2B)

AFUL:

116486186(ACVR2B)

TGU:	100230960(ACVR2B)

LSR:	110484564(ACVR2B)

SCAN:

103812710(ACVR2B)

PMOA:

120500601(ACVR2B)

OTC:	121338056(ACVR2B)

PRUF:

121364655(ACVR2B)

ATRC:

139590794(ACVR2B)

GFR:	102041687(ACVR2B)

FAB:	101819929(ACVR2B)

OMA:	130250179(ACVR2B)

PHI:	102107002(ACVR2B)

PMAJ:

107200862(ACVR2B)

CCAE:

111925449(ACVR2B)

CCW:	104686423(ACVR2B)

CBRC:

103623945(ACVR2B)

ACOE:

138106190(ACVR2B)

ETL:

114062268

ZAB:	102063636(ACVR2B)

ZLE:	135443560(ACVR2B)

ACHL:

103799873

SVG:	106851614(ACVR2B)

MMEA:

130573157(ACVR2B)

HRT:	120753601(ACVR2B)

SATI:

136361608(ACVR2B)

CFAI:

136299543(ACVR2B)

CCIC:

134044406(ACVR2B)

FPG:	101918473(ACVR2B)

FCH:	102048434(ACVR2B)

CCRI:

104165928(ACVR2B)

NNT:	104405537(ACVR2B)

SHAB:

115610381(ACVR2B)

ACUN:

113476614(ACVR2B)

SURA:

141943631(ACVR2B)

TALA:

104367124(ACVR2B)

ACHC:

115339661(ACVR2B)

HALD:

104325358(ACVR2B)

HLE:	104843334(ACVR2B)

AGEN:

126037729

HHAR:

128150813(ACVR2B)

BBUT:

142038914(ACVR2B)

GCL:

127013411

CSTI:

104555771(ACVR2B)

LDI:

104352158

MNB:

103775018

DPUB:

104297850(ACVR2B)

PPUS:

135185757(ACVR2B)

AVIT:

104278322(ACVR2B)

BRHI:

104501810(ACVR2B)

EGZ:	104130967(ACVR2B)

NNI:	104014900(ACVR2B)

PCRI:

104033700

PCAO:

104051210(ACVR2B)

PADL:

103915643(ACVR2B)

AFOR:

103905997(ACVR2B)

FGA:	104072728(ACVR2B)

CBOR:

142079647(ACVR2B)

GSTE:

104257441(ACVR2B)

CBOY:

140648560(ACVR2B)

MAME:

142405261(ACVR2B)

CLV:	102083697(ACVR2B)

CNIC:

135985535(ACVR2B)

MUI:	104537228(ACVR2B)

PGUU:

104461241

PLET:

104618121

EHS:	104514325(ACVR2B)

CMAC:

104482495(ACVR2B)

CUCA:

104056984(ACVR2B)

TEO:	104382073(ACVR2B)

BREG:

104632672

GAME:

129203121(ACVR2B)

OHA:	104337202(ACVR2B)

ACAR:

104527636(ACVR2B)

CPEA:

104396178(ACVR2B)

CVF:	104288899(ACVR2B)

RTD:	128905680(ACVR2B)

CRID:

134511033(ACVR2B)

LMIC:

141738601(ACVR2B)

NARQ:

141470885(ACVR2B)

AAM:	106490270(ACVR2B)

AROW:

112978289(ACVR2B)

NPD:	112958098(ACVR2B)

TGT:

104575645

DNE:	112981563(ACVR2B)

SCAM:

104148847(ACVR2B)

ASN:	102381128(ACVR2B)

AMJ:	102568461(ACVR2B)

CPOO:

109306693(ACVR2B)

GGN:	109291215(ACVR2B)

PSS:	102452383(ACVR2B)

CIZ:	142008133(ACVR2B)

CMY:	102930932(ACVR2B)

CCAY:

125631207(ACVR2B)

LKP:	140907818(ACVR2B)

NDS:	141983314(ACVR2B)

DCC:	119851776(ACVR2B)

CPIC:

101948494(ACVR2B)

TST:	117872009(ACVR2B)

CABI:

116829938(ACVR2B)

MRV:	120398326(ACVR2B)

ACS:	100565604(acvr2b)

ASAO:

132778995(ACVR2B)

PVT:	110071927(ACVR2B)

SUND:

121934211(ACVR2B)

PBI:	103067229(ACVR2B)

PMUR:

107303318(ACVR2B)

CTIG:

120304070(ACVR2B)

TSR:	106556961(ACVR2B)

PGUT:

117654751(ACVR2B)

APRI:

131197089(ACVR2B)

PTEX:

113447988(ACVR2B)

NSS:	113419516(ACVR2B)

VKO:	123020939(ACVR2B)

PMUA:

114607551(ACVR2B)

PRAF:

128424083(ACVR2B)

ZVI:	118092384(ACVR2B)

HCG:	128329227(ACVR2B)

GJA:	107120367(ACVR2B)

STOW:

125440643(ACVR2B)

EMC:	129337395(ACVR2B)

XLA:	397859(acvr2b.S) 399277(acvr2b.L)

XTR:	448641(acvr2b)

NPR:	108784618(ACVR2B)

RTEM:

120940112(ACVR2B)

ACAT:

141145949(ACVR2B)

PADS:

140331508(ACVR2B)

BBUF:

121002415(ACVR2B)

BGAR:

122938936(ACVR2B)

DTC:	141088067 141095516(ACVR2B)

PWL:	138261761(ACVR2B)

MUO:	115466717(ACVR2B)

GSH:	117354343(ACVR2B)

DRE:	100331938(acvr2bb) 30457(acvr2ba)

SRX:	107713688 107729982 107742188

SANH:

107655843 107676805(acvr2b) 107687130 107696796

SGH:	107554365(acvr2b) 107558294 107560362 107600193

CCAR:

109072288 109111999

CAUA:

113042624 113068765 113079294 113112785

CGIB:

127937437 127946334 127951478 128013476

PTET:

122329396(acvr2ba) 122362952

LROH:

127154964 127155981(acvr2ba)

GRF:	141300382(acvr2ba) 141343999(acvr2bb)

OMC:	131526670 131533459(acvr2ba)

PPRM:

120482740 120488054(acvr2ba)

RKG:	130096932(acvr2ba) 130105573

MAMB:

125250494 125257906(acvr2ba)

CIDE:

127494623

CERY:

137003052 137014005(acvr2ba)

MASI:

127431920 127434624 127440677 127443153

TROS:

130547097(acvr2ba) 130554792

TDW:	130413238(acvr2ba) 130418246

MANU:

129426224(acvr2ba) 129441764(acvr2bb)

PDAB:

135740519(acvr2ba) 135767054(acvr2bb)

IPU:	108271385(acvr2ba) 108280686

IFU:	128614007(acvr2ba) 128624261

PHYP:

113526519(acvr2b) 113533545

SMEO:

124385051(acvr2ba) 124403216

TFD:	113644789(acvr2ba) 113645308

TVC:	132845253(acvr2ba) 132845857

CGAR:

128513276 128519706(acvr2ba)

NGRA:

132871758 132887073(acvr2ba)

TRN:	134302353 134310470(acvr2ba)

AMEX:

103035375 103040683(acvr2ba)

CMAO:

118797017 118821139(acvr2ba)

EEE:	113568488 113583392

CHAR:

105892316 105894788(acvr2ba)

SPIL:

134063647 134065909

ASAD:

121688522 121713023

TRU:	101063689(acvr2b)

TFS:	130538481(acvr2ba)

TNG:	GSTEN00031859G001

LCO:

104932045

NCC:	104965683(acvr2b)

TBEN:

117475720 117500311(acvr2ba)

CGOB:

115022968(acvr2b)

PGEO:

117462420(acvr2ba)

GACU:

117542094(acvr2ba) 117542385

EMAC:

134858114 134866360

ELY:	117264878 117271968

EFO:	125882113 125902248

PLEP:

121951894(acvr2ba)

SLUC:

116045863(acvr2ba) 116061931

ECRA:

117954451(acvr2ba)

ESP:	116698894(acvr2b)

PFLV:

114548898 114565748(acvr2b)

GAT:	120811935 120815887

PPUG:

119198333 119209512

AFB:

129112578

CLUM:

117746634 117749510

PSWI:

130197544(acvr2ba)

CANA:

137782129 137789090

CVE:	137865895 137892159

MSAM:

119897268 119901828

SCHU:

122866474(acvr2ba) 122887024

EARM:

139296130 139304594 139307159

CUD:

121520575

SPUL:

138596018(acvr2ba) 138611806

LMIX:

132979431 132994133

HTC:	141804439 141807299(acvr2ba)

ALAT:

119008851(acvr2ba) 119011671

ASTR:

137612719 137614025

PKLU:

139214777

MZE:	101465379 101478569

ONL:	100691414 100699754

OAU:	116313384 116336526

OLA:	101161926 101171650

OML:	112141895 112151374(acvr2ba)

CSAI:

133423498(acvr2ba) 133451869

XMA:	102217889 102223036

XCO:	114136607 114146822

XHE:	116711769 116722091(acvr2b)

PRET:

103479741(acvr2b)

PFOR:

103146340(acvr2b)

PLAI:

106945320(acvr2b)

PMEI:

106933669(acvr2b)

GAF:	122824422 122840858

PPRL:

129378060(acvr2ba)

CVG:	107089450 107103356(acvr2b)

CTUL:

119777281 119787174

GMU:	124857980 124870275

NFU:

107383557

KMR:	108228932 108232890

ALIM:

106516905 106534051

NWH:	119414742 119426543

AOCE:

111576974 111587864(acvr2ba)

EJA:	138203180 138215437

BFRE:

138617435 138633769(acvr2ba)

MCEP:

125010197 125024358

CSEM:

103377337 103396513

POV:	109646928(acvr2b)

SSEN:

122771008 122776430

SSOE:

131462390 131463054

HHIP:

117754276 117778096(acvr2ba)

HSP:	118098463 118117763

PPLT:

128425673 128455057

SMAU:

118290978(acvr2ba) 118310724

LCF:	108884221 108891453(acvr2ba)

SDU:	111231005 111237400

SLAL:

111647265 111655881

XGL:	120789891(acvr2ba) 120799494

HCQ:	109507463(acvr2b)

SSCV:

125985173

SBIA:

133510759(acvr2ba)

PEE:	133411990(acvr2ba)

PTAO:

133489311(acvr2ba)

BPEC:

110153465(acvr2b)

ENY:	140356028 140364914

MALB:

109955427

BSPL:

114844641 114853960(acvr2ba)

SJO:	128368931 128382139

SSCO:

133990387 134002032

TTY:	137173341(acvr2ba) 137194471

GMH:	115537430 115548544(acvr2b)

SASA:

100136506 106569759 106590375(acvr2b)

STRU:

115150309 115157595 115195559

OTW:	112215332 112227771 112238875

OMY:	100301655(actriib) 110531045 110535274

OGO:	123991371 124039612

ONE:	115104882 115130190(acvr2b)

OKI:	109881054 109899315 109909823

OKE:	118361196 118370799 118377485

OMM:	135509056 135517299 135522886

OCLA:

139367025 139386826 139420200

SALP:

111953775 112068569

SNH:	120027789 120051025 120055443

SFON:

129813675 129823068 129859191

CCLU:

121535700 121549654 121569187 121580573

ELS:	105025736(acvr2b) 105030502

OEP:	134034631 134036624

SFM:	108927975(acvr2b)

PKI:	111849750 111850174

AANG:

118226368 118234098

AROT:

135252700 135260955

CCOG:

133126556(acvr2ba) 133137044

LOC:	102683870(acvr2b)

PSPA:

121310004 121314044

ARUT:

117394817 117400503

PSEX:

120529658(acvr2ba)

LCM:	102351086(ACVR2B)

CMK:	103191390 121851978

CPLA:

122550141

CPUN:

140480289

HOC:	132814274 132816241

SCAU:

119966571(acvr2ba)

STOZ:

140424755

LERI:

129714273

HAKA:

140732390(acvr2ba)

PMRN:

116938784 116940847 116948637(ACVR2A) 116949598

LRJ:	133338969 133340074 133345289 133345881 133349725 133361805 133362454 133362609 133362612 133362616 133362676

BFO:

118403120

CIN:	778777(tgfbr-iia)

SCLV:

CLEP:

SPU:

APLC:

AFIL:

AJC:

SKO:

PFLL:

DME:	Dmel_CG7904(put)

DER:

6552862

DSE:

6606376

DSI:	Dsimw501_GD20410(Dsim_GD20410)

DYA:	Dyak_GE26437

DAN:

DSR:

DPO:

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI10656

DAZ:

108621743

DNV:

108653754

DHE:

111596865

DVI:	6630944(put)

CCAT:

BOD:

BDR:

RZE:

AOQ:

ALUD:

TDA:	119675870 119679558

MDE:

SCAC:

LCQ:

LSQ:

CVJ:	135963594(put)

GFS:

ECOE:

CLON:

HIS:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AMAP:

AFUN:

AMOU:

AMRS:

AALI:

ADAR:

ACOS:

AAG:

AALB:

ASUA:

CQU:	CpipJ_CPIJ017753

CPII:

120419281

CBRI:

134829480

CNS:	116337688 116337702

BCOO:

LLL:

PPAP:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BHUN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

ACOC:

MZT:	108730852(put)

CCOA:

TCZ:

TSEP:

PBAR:

VEM:

COBS:

139103810(Put)

TLN:	139808613(Put)

TAME:

143899934(Put)

HST:

DQU:

CFO:

FEX:

PMEC:

138943553(Put)

LHU:	105672548(put)

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

TPRE:

LHT:

LBD:

MDL:

CGLO:

CTYP:

141529887(Put)

FAS:

DAM:

AGIF:

CINS:

VCAN:

CCIN:

DSM:

NPT:	124216868(put)

NFB:

NLO:

NVG:

AROA:

TCA:	654851(punt)

TMOL:

138136204(put)

DPA:

109532768

ESIM:

136416024(put)

EFOR:

136347907(put)

RFG:	143190206(put)

ATD:

HAXR:

DVV:

NVL:

BMOR:

BMAN:

MSEX:

DPL:	KGM_204127

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

BPHI:

137924173(put)

PRAP:

PBX:

PNAP:

ZCE:

CCRC:

LSIN:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:

ONU:

ATRA:

GMW:	113523381 128200143

PXY:

PGW:

LGLY:

CSTB:

CFUM:

CFEL:

API:

DNX:

AGS:

RMD:

ACOO:

DVT:

BTAB:

CLEC:

NLU:

LDA:	142329991(put)

ZNE:

110840739

CSEC:

111871304

PAME:

138694931(put)

BROR:

134533135

IEL:

124161721

HAMR:

139690997(put)

AFRA:

PVM:

PMOO:

CQD:

MNZ:

MRJ:

PORN:

139757804(put)

OOT:	143037843(put)

EAF:

111707021

LSM:	121113732(put)

PPOI:

119090408

DSV:	119455414 119455415

DALB:

135915387(put)

RSAN:

119394358

RMP:

119172399

GOE:	100907906 100908425

DPTE:

113799432

DFR:

124500176

CSCU:

111625691

CVS:	136987084 136989060(put)

PTEP:

107436981

ABRU:

129959987

UDV:	129231635 129231636

SDM:

118190282

LPOL:

106461949 106469210 106472446

PMEO:

129587660

CEL:	CELE_C05D2.1(daf-4)

CBR:	CBG_08963(Cbr-daf-4)

CRQ:	GCK72_010584

LOA:	LOAG_00024

TSP:

Tsp_06484

HRO:	HELRODRAFT_89946

PVUL:

LSAX:

BARL:

GAE:

HRF:

HRJ:

HASI:

HCRA:

CRG:	105323135(Actr2)

CANU:

PMAX:

AIRR:

YBA:

OBI:

OSN:	115220851 115231493

LJP:

135461781

LAK:

106166288

SMM:	Smp_080120.1

OVI:	T265_11493

LLON:

NVE:

EPA:

ADF:

MFOO:

HMG:

HSY:	130622202 130644882 130647094

RES:

135685961

TAD:	TRIADDRAFT_3190

» show all

Reference

PMID:8161782

Authors

Hilden K, Tuuri T, Eramaa M, Ritvos O

Title

Expression of type II activin receptor genes during differentiation of human K562 cells and cDNA cloning of the human type IIB activin receptor.

Journal

Blood 83:2163-70 (1994)

Sequence

[hsa:93]

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