KEGG ORTHOLOGY: K13601

ORTHOLOGY: K13601

Entry

K13601                      KO

Symbol

bchQ

Name

bacteriochlorophyllide d C-8(2)-methyltransferase [EC:2.1.1.332]

Pathway

map00860

Porphyrin metabolism

map01110

Biosynthesis of secondary metabolites

Reaction

R11508

S-adenosyl-L-methionine:8,12-diethyl-3-vinylbacteriochlorophyllide-d C-8(2)-methyltransferase

R11509

S-adenosyl-L-methionine:12-ethyl-8-propyl-3-vinylbacteriochlorophyllide d C-8(2)-methyltransferase

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00860 Porphyrin metabolism
    K13601  bchQ; bacteriochlorophyllide d C-8(2)-methyltransferase
Enzymes [BR:ko01000]
2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.332  bacteriochlorophyllide d C-82-methyltransferase
     K13601  bchQ; bacteriochlorophyllide d C-8(2)-methyltransferase

Other DBs

COG:

COG1032

Genes

CTE:	CT1777(bchQ)

CPC:

Cpar_0429

CLZ:	BIU88_02080 BIU88_11025

CCH:

Cag_0116

CPH:	Cpha266_0200

CPB:	Cphamn1_0267

CLI:

Clim_1975

PVI:

Cvib_0369

PLT:

Plut_0407

PPH:	Ppha_2731 Ppha_2757

PAA:

Paes_1806

PROC:

Ptc2401_01903

PRS:	B9H02_09075

PROS:

PROW:

PROI:

CTS:

Reference

PMID:17586634

Authors

Gomez Maqueo Chew A, Frigaard NU, Bryant DA

Title

Bacteriochlorophyllide c C-8(2) and C-12(1) methyltransferases are essential for adaptation to low light in Chlorobaculum tepidum.

Journal

J Bacteriol 189:6176-84 (2007)
DOI:10.1128/JB.00519-07

Sequence

[cte:CT1777]

Reference

PMID:17506685

Authors

Chew AG, Bryant DA

Title

Chlorophyll biosynthesis in bacteria: the origins of structural and functional diversity.

Journal

Annu Rev Microbiol 61:113-29 (2007)
DOI:10.1146/annurev.micro.61.080706.093242

LinkDB

ENZYME: 2.1.1.332

Entry

EC 2.1.1.332                Enzyme

Name

bacteriochlorophyllide d C-82-methyltransferase;
bchQ (gene name)

Class

Transferases;
Transferring one-carbon groups;
Methyltransferases

Sysname

S-adenosyl-L-methionine:8,12-diethyl-3-vinylbacteriochlorophyllide-d C-82-methyltransferase

Reaction(IUBMB)

(1) S-adenosyl-L-methionine + 8,12-diethyl-3-vinylbacteriochlorophyllide d = S-adenosyl-L-homocysteine + 12-ethyl-8-propyl-3-vinylbacteriochlorophyllide d [RN:R11508];
(2) S-adenosyl-L-methionine + 12-ethyl-8-propyl-3-vinylbacteriochlorophyllide d = S-adenosyl-L-homocysteine + 12-ethyl-8-isobutyl-3-vinylbacteriochlorophyllide d [RN:R11509]

Reaction(KEGG)

R11508 R11509

Substrate

S-adenosyl-L-methionine [CPD:C00019];
8,12-diethyl-3-vinylbacteriochlorophyllide d [CPD:C21427];
12-ethyl-8-propyl-3-vinylbacteriochlorophyllide d [CPD:C21428]

Product

S-adenosyl-L-homocysteine [CPD:C00021];
12-ethyl-8-propyl-3-vinylbacteriochlorophyllide d [CPD:C21428];
12-ethyl-8-isobutyl-3-vinylbacteriochlorophyllide d [CPD:C21429]

Comment

This enzyme, found in green sulfur bacteria (Chlorobiaceae) and green flimentous bacteria (Chloroflexaceae), is a radical S-adenosyl-L-methionine (AdoMet) enzyme and contains a [4Fe-4S] cluster. It adds one or two methyl groups at the C-82 position of bacteriochlorophylls of the c, d, and e types. These methylations play a role in fine-tuning the structural arrangement of the bacteriochlorophyll aggregates in chlorosomes and therefore directly influence chlorosomal absorption properties.

History

EC 2.1.1.332 created 2016

Pathway

ec00860

Porphyrin metabolism

ec01110

Biosynthesis of secondary metabolites

Orthology

K13601

bacteriochlorophyllide d C-8(2)-methyltransferase

Genes

CTE:	CT1777(bchQ)

CPC:

Cpar_0429

CLZ:	BIU88_02080 BIU88_11025

CCH:

Cag_0116

CPH:	Cpha266_0200

CPB:	Cphamn1_0267

CLI:

Clim_1975

PVI:

Cvib_0369

PLT:

Plut_0407

PPH:	Ppha_2731 Ppha_2757

PAA:

Paes_1806

PROC:

Ptc2401_01903

PRS:	B9H02_09075

PROS:

CHL67_01205

PROW:

OO006_13050

PROI:

OO005_12020

CTS:

Ctha_1292

» show all

Reference

1 [PMID:17586634]

Authors

Gomez Maqueo Chew A, Frigaard NU, Bryant DA

Title

Bacteriochlorophyllide c C-8(2) and C-12(1) methyltransferases are essential for adaptation to low light in Chlorobaculum tepidum.

Journal

J Bacteriol 189:6176-84 (2007)
DOI:10.1128/JB.00519-07

Sequence

[cte:CT1777]

Other DBs

ExplorEnz - The Enzyme Database:

2.1.1.332

IUBMB Enzyme Nomenclature:

2.1.1.332

ExPASy - ENZYME nomenclature database:

2.1.1.332

BRENDA, the Enzyme Database:

2.1.1.332

LinkDB

REACTION: R11509

Entry

R11509                      Reaction

Name

S-adenosyl-L-methionine:12-ethyl-8-propyl-3-vinylbacteriochlorophyllide d C-8(2)-methyltransferase

Definition

12-Ethyl-8-propyl-3-vinylbacteriochlorophyllide d + S-Adenosyl-L-methionine <=> 12-Ethyl-8-isobutyl-3-vinylbacteriochlorophyllide d + S-Adenosyl-L-homocysteine

Equation

C21428 + C00019 <=> C21429 + C00021

Comment

radical SAM

Reaction class

RC03459

C21428_C21429

Enzyme

2.1.1.332

Pathway

rn00860

Porphyrin metabolism

rn01110

Biosynthesis of secondary metabolites

Brite

Enzymatic reactions [BR:br08201]
2. Transferase reactions
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.332
     R11509  12-Ethyl-8-propyl-3-vinylbacteriochlorophyllide d + S-Adenosyl-L-methionine <=> 12-Ethyl-8-isobutyl-3-vinylbacteriochlorophyllide d + S-Adenosyl-L-homocysteine

Orthology

K13601

bacteriochlorophyllide d C-8(2)-methyltransferase [EC:2.1.1.332]

Other DBs

RHEA:

49179

LinkDB

DBGET integrated database retrieval system