KEGG   ORTHOLOGY: K13602
Entry
K13602                      KO                                     
Symbol
bchR
Name
bacteriochlorophyllide d C-12(1)-methyltransferase [EC:2.1.1.331]
Pathway
map00860  Porphyrin metabolism
map01110  Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00860 Porphyrin metabolism
    K13602  bchR; bacteriochlorophyllide d C-12(1)-methyltransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.331  bacteriochlorophyllide d C-121-methyltransferase
     K13602  bchR; bacteriochlorophyllide d C-12(1)-methyltransferase
Other DBs
RN: R11507
COG: COG1032
Genes
CTE: CT1320
CPC: Cpar_1337
CLZ: BIU88_04215
CCH: Cag_0931
CPH: Cpha266_1644
CPB: Cphamn1_1023
CLI: Clim_1516
PVI: Cvib_1051
PLT: Plut_1318
PPH: Ppha_1617
PAA: Paes_1466
CTS: Ctha_2306
 » show all
Reference
  Authors
Gomez Maqueo Chew A, Frigaard NU, Bryant DA
  Title
Bacteriochlorophyllide c C-8(2) and C-12(1) methyltransferases are essential for adaptation to low light in Chlorobaculum tepidum.
  Journal
J Bacteriol 189:6176-84 (2007)
DOI:10.1128/JB.00519-07
  Sequence
[cte:CT1320]
Reference
  Authors
Chew AG, Bryant DA
  Title
Chlorophyll biosynthesis in bacteria: the origins of structural and functional diversity.
  Journal
Annu Rev Microbiol 61:113-29 (2007)
DOI:10.1146/annurev.micro.61.080706.093242
LinkDB

KEGG   ENZYME: 2.1.1.331
Entry
EC 2.1.1.331                Enzyme                                 
Name
bacteriochlorophyllide d C-121-methyltransferase;
bchR (gene name)
Class
Transferases;
Transferring one-carbon groups;
Methyltransferases
Sysname
S-adenosyl-L-methionine:8-ethyl-12-methyl-3-vinylbacteriochlorophyllide-d C-121-methyltransferase
Reaction(IUBMB)
S-adenosyl-L-methionine + 8-ethyl-12-methyl-3-vinylbacteriochlorophyllide d = S-adenosyl-L-homocysteine + 8,12-diethyl-3-vinylbacteriochlorophyllide d [RN:R11507]
Reaction(KEGG)
R11507
Substrate
S-adenosyl-L-methionine [CPD:C00019];
8-ethyl-12-methyl-3-vinylbacteriochlorophyllide d [CPD:C18157]
Product
S-adenosyl-L-homocysteine [CPD:C00021];
8,12-diethyl-3-vinylbacteriochlorophyllide d [CPD:C21427]
Comment
This enzyme, found in green sulfur bacteria (Chlorobiaceae) and green flimentous bacteria (Chloroflexaceae), is a radical S-adenosyl-L-methionine (AdoMet) enzyme and contains a [4Fe-4S] cluster. It adds a methyl group at the C-121 position of bacteriochlorophylls of the c, d and e types. This methylation plays a role in fine-tuning the structural arrangement of the bacteriochlorophyll aggregates in chlorosomes and therefore directly influences the chlorosomes absorption properties.
History
EC 2.1.1.331 created 2016
Pathway
ec00860  Porphyrin metabolism
ec01110  Biosynthesis of secondary metabolites
Orthology
K13602  bacteriochlorophyllide d C-12(1)-methyltransferase
Genes
CTECT1320
CPCCpar_1337
CLZBIU88_04215
CCHCag_0931
CPHCpha266_1644
CPBCphamn1_1023
CLIClim_1516
PVICvib_1051
PLTPlut_1318
PPHPpha_1617
PAAPaes_1466
PROCPtc2401_00733
PRSB9H02_04365
PROSCHL67_04105
CTSCtha_2306
 » show all
Reference
1  [PMID:17586634]
  Authors
Gomez Maqueo Chew A, Frigaard NU, Bryant DA
  Title
Bacteriochlorophyllide c C-8(2) and C-12(1) methyltransferases are essential for adaptation to low light in Chlorobaculum tepidum.
  Journal
J Bacteriol 189:6176-84 (2007)
DOI:10.1128/JB.00519-07
  Sequence
[cte:CT1320]
Other DBs
ExplorEnz - The Enzyme Database: 2.1.1.331
IUBMB Enzyme Nomenclature: 2.1.1.331
ExPASy - ENZYME nomenclature database: 2.1.1.331
BRENDA, the Enzyme Database: 2.1.1.331
LinkDB

KEGG   REACTION: R11507
Entry
R11507                      Reaction                               
Name
S-adenosyl-L-methionine:8-ethyl-12-methyl-3-vinylbacteriochlorophyllide-d C-12(1)-methyltransferase
Definition
8-Ethyl-12-methyl-3-vinylbacteriochlorophyllide d + S-Adenosyl-L-methionine <=> 8,12-Diethyl-3-vinylbacteriochlorophyllide d + S-Adenosyl-L-homocysteine
Equation
Comment
radical SAM
Reaction class
RC03457  C18157_C21427
Enzyme
Pathway
rn00860  Porphyrin metabolism
rn01110  Biosynthesis of secondary metabolites
Orthology
K13602  bacteriochlorophyllide d C-12(1)-methyltransferase [EC:2.1.1.331]
Other DBs
RHEA: 49171
LinkDB

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