KEGG   ORTHOLOGY: K14272
Entry
K14272                      KO                                     
Symbol
GGAT
Name
glutamate--glyoxylate aminotransferase [EC:2.6.1.4 2.6.1.2 2.6.1.44]
Pathway
map00220  Arginine biosynthesis
map00250  Alanine, aspartate and glutamate metabolism
map00260  Glycine, serine and threonine metabolism
map00630  Glyoxylate and dicarboxylate metabolism
map00710  Carbon fixation in photosynthetic organisms
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
map01120  Microbial metabolism in diverse environments
map01200  Carbon metabolism
map01210  2-Oxocarboxylic acid metabolism
map01230  Biosynthesis of amino acids
Module
M00171  C4-dicarboxylic acid cycle, NAD - malic enzyme type
M00532  Photorespiration
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00630 Glyoxylate and dicarboxylate metabolism
    K14272  GGAT; glutamate--glyoxylate aminotransferase
  09102 Energy metabolism
   00710 Carbon fixation in photosynthetic organisms
    K14272  GGAT; glutamate--glyoxylate aminotransferase
  09105 Amino acid metabolism
   00250 Alanine, aspartate and glutamate metabolism
    K14272  GGAT; glutamate--glyoxylate aminotransferase
   00260 Glycine, serine and threonine metabolism
    K14272  GGAT; glutamate--glyoxylate aminotransferase
   00220 Arginine biosynthesis
    K14272  GGAT; glutamate--glyoxylate aminotransferase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01007 Amino acid related enzymes
    K14272  GGAT; glutamate--glyoxylate aminotransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.6  Transferring nitrogenous groups
   2.6.1  Transaminases
    2.6.1.2  alanine transaminase
     K14272  GGAT; glutamate--glyoxylate aminotransferase
    2.6.1.4  glycine transaminase
     K14272  GGAT; glutamate--glyoxylate aminotransferase
    2.6.1.44  alanine---glyoxylate transaminase
     K14272  GGAT; glutamate--glyoxylate aminotransferase
Amino acid related enzymes [BR:ko01007]
 Aminotransferase (transaminase)
  Class I
   K14272  GGAT; glutamate--glyoxylate aminotransferase
Other DBs
RN: R00258 R00369 R00372
GO: 0047958 0004021 0008453
Genes
AJM: 119064613
ATH: AT1G23310(GGT1) AT1G70580(AOAT2)
ALY: 9323376 9329338
CRB: 17895448 17897757
CSAT: 104701699 104712607 104741047 104750897 104756699 104776459
EUS: EUTSA_v10007514mg EUTSA_v10018474mg
BRP: 103829276 103831592 103835672 103840779
BNA: 106358129 106406022 106415204 106434229 106440992 111207231
BOE: 106295814 106296220 106312468
RSZ: 108808579 108822099 108822100 108825821
THJ: 104822983
CPAP: 110817151
CIT: 102611899
PVY: 116118556
TCC: 18609536
GRA: 105794627
GAB: 108473496
EGR: 104414150
GMX: 100127414(ALAAT2) 100787173
VRA: 106777621
VAR: 108329166
VUN: 114173720
CCAJ: 109800924
APRC: 113869499
MTR: 11409437
CAM: 101508288
PSAT: 127119265
LJA: Lj2g3v1415440.1(Lj2g3v1415440.1) Lj2g3v1415440.2(Lj2g3v1415440.2) Lj2g3v1415440.3(Lj2g3v1415440.3)
ADU: 107488817
AIP: 107643316
FVE: 101304831
RCN: 112197874
PPER: 18788891
PMUM: 103321858
PAVI: 110760503
PDUL: 117624640
PXB: 103949832
ZJU: 107428611
MNT: 21410308
RCU: 8273496
JCU: 105644652
QSU: 112010088
QLO: 115982489
TWL: 119999892
VVI: 100261274
VRI: 117913055
INI: 109172057
ITR: 116025572
EGT: 105968054
APAN: 127245394
HAN: 110871636
LSV: 111882299
CCAV: 112524428
BVG: 104897276
SOE: 110799230
NNU: 104593113
MING: 122061852
TSS: 122672852
OSA: 4342210
DOSA: Os07t0108300-01(Os07g0108300)
OBR: 102712276
BDI: 100844005
ATS: 109734653
TUA: 125537550
LPER: 127334108
SBI: 110432565
SITA: 101767913
SVS: 117845035
PHAI: 112882121
DCT: 110110983
PEQ: 110023535
AOF: 109833434
NCOL: 116264138
ATR: 18430615
MNG: MNEG_0384
APRO: F751_3918
 » show all
Reference
PMID:3933486
  Authors
Takada Y, Noguchi T
  Title
Characteristics of alanine: glyoxylate aminotransferase from Saccharomyces cerevisiae, a regulatory enzyme in the glyoxylate pathway of glycine and serine biosynthesis from tricarboxylic acid-cycle intermediates.
  Journal
Biochem J 231:157-63 (1985)
DOI:10.1042/bj2310157
Reference
  Authors
Foyer CH, Bloom AJ, Queval G, Noctor G
  Title
Photorespiratory metabolism: genes, mutants, energetics, and redox signaling.
  Journal
Annu Rev Plant Biol 60:455-84 (2009)
DOI:10.1146/annurev.arplant.043008.091948
Reference
  Authors
Liepman AH, Olsen LJ
  Title
Alanine aminotransferase homologs catalyze the glutamate:glyoxylate aminotransferase reaction in peroxisomes of Arabidopsis.
  Journal
Plant Physiol 131:215-27 (2003)
DOI:10.1104/pp.011460
  Sequence
LinkDB

KEGG   ENZYME: 2.6.1.4
Entry
EC 2.6.1.4                  Enzyme                                 
Name
glycine transaminase;
glutamic-glyoxylic transaminase;
glycine aminotransferase;
glyoxylate-glutamic transaminase;
L-glutamate:glyoxylate aminotransferase;
glyoxylate-glutamate aminotransferase
Class
Transferases;
Transferring nitrogenous groups;
Transaminases
Sysname
glycine:2-oxoglutarate aminotransferase
Reaction(IUBMB)
glycine + 2-oxoglutarate = glyoxylate + L-glutamate [RN:R00372]
Reaction(KEGG)
R00372
Substrate
glycine [CPD:C00037];
2-oxoglutarate [CPD:C00026]
Product
glyoxylate [CPD:C00048];
L-glutamate [CPD:C00025]
Comment
A pyridoxal-phosphate protein.
History
EC 2.6.1.4 created 1961, modified 1982
Pathway
ec00260  Glycine, serine and threonine metabolism
ec00630  Glyoxylate and dicarboxylate metabolism
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Orthology
K14272  glutamate--glyoxylate aminotransferase
Genes
AJM119064613
ATHAT1G23310(GGT1) AT1G70580(AOAT2)
ALY9323376 9329338
CRB17895448 17897757
CSAT104701699 104712607 104741047 104750897 104756699 104776459
EUSEUTSA_v10007514mg EUTSA_v10018474mg
BRP103829276 103831592 103835672 103840779
BNA106358129 106406022 106415204 106434229 106440992 111207231
BOE106295814 106296220 106312468
RSZ108808579 108822099 108822100 108825821
THJ104822983
CPAP110817151
CIT102611899
CICCICLE_v10031381mg
PVY116118556
MINC123214620 123217376
TCC18609536
GRA105794627
GHI107909695 121219607
GAB108473496
DZI111287321 111317434
EGR104414150
GMX100127414(ALAAT2) 100787173
GSJ114380572 114409594
PVUPHAVU_002G150800g
VRA106777621
VAR108329166
VUN114173720
CCAJ109800924
APRC113869499
MTR11409437
CAM101508288
PSAT127119265
LJALj2g3v1415440.1(Lj2g3v1415440.1) Lj2g3v1415440.2(Lj2g3v1415440.2) Lj2g3v1415440.3(Lj2g3v1415440.3)
ADU107488817
AIP107643316
AHF112749967 112801167
LANG109331712 109333110 109349171
FVE101304831
RCN112197874
PPER18788891
PMUM103321858
PAVI110760503
PDUL117624640
MDM103403075 103452041
PXB103949832
ZJU107428611
MNT21410308
CSV101207914 101213570 101220645
CMO103487718 103489552
BHJ120076884 120081674 120081935
MCHA111004830 111019711
CMAX111466383 111483054 111483066 111491846
CMOS111449625 111458746 111458747 111462665
CPEP111785992 111802348 111802408 111804951 111808545
RCU8273496
JCU105644652
HBR110640694 110645911
MESC110627295 110629550
POP7460760 7469050
PEU105118417 105132439
PALZ118037955 118045367
JRE108985586 108989739
CILL122311265 122314303
QSU112010088
QLO115982489
TWL119999892
VVI100261274
VRI117913055
SLY101251709 101265236
SPEN107020278 107028658
SOT102586190 102591453
SSTN125841717 125867774
CANN107838723 107847729
NTA107797758 107803058 107806358 107829867
NSY104212315 104216677
NTO104114985 104115495
NAU109209329 109213708
INI109172057
ITR116025572
SIND105156639 105168292
OEU111395357 111404811 111406319
EGT105968054
SSPL121768294 121768295 121771524 121771525
APAN127245394
HAN110871636
ECAD122595142 122598267
LSV111882299
CCAV112524428
DCR108194271 108202675 108210226
CSIN114301050 114311865
BVG104897276
SOE110799230
CQI110709241 110712582
NNU104593113
MING122061852
TSS122672852
PSOM113287399 113288598 113318436
OSA4342210
DOSAOs07t0108300-01(Os07g0108300)
OBR102712276
BDI100844005
ATS109734653
TDC119354714 119363905
TAES123045110 123052946 123188854
TUA125537550
LPER127334108
SBI110432565
ZMA100284842 100501386
SITA101767913
SVS117845035
PVIR120659204 120660037
PHAI112882121
PDA103707141 103717660
EGU105049882 105050532
MUS103989410 103994683
ZOF122002097 122006353
DCT110110983
PEQ110023535
AOF109833434
NCOL116264138
ATR18430615
SMOSELMODRAFT_145611 SELMODRAFT_267931
PPP112277304 112282312 112293257
CRECHLRE_10g451950v5
VCNVOLCADRAFT_73258
MNGMNEG_0384
CSLCOCSUDRAFT_26706
CVRCHLNCDRAFT_57929
APROF751_3918
SREPTSG_06899
GLAGL50803_0016363
 » show all
Reference
1  [PMID:14169146]
  Authors
NAKADA HI.
  Title
GLUTAMIC-GLYCINE TRANSAMINASE FROM RAT LIVER.
  Journal
J Biol Chem 239:468-71 (1964)
Reference
2
  Authors
Thompson, J.S. and Richardson, K.E.
  Title
Isolation and chracterization of a glutamate-glycine transaminase from human liver.
  Journal
Arch Biochem Biophys 117:599-603 (1966)
Other DBs
ExplorEnz - The Enzyme Database: 2.6.1.4
IUBMB Enzyme Nomenclature: 2.6.1.4
ExPASy - ENZYME nomenclature database: 2.6.1.4
BRENDA, the Enzyme Database: 2.6.1.4
CAS: 9032-99-9
LinkDB

KEGG   REACTION: R00372
Entry
R00372                      Reaction                               
Name
Glycine:2-oxoglutarate aminotransferase
Definition
Glycine + 2-Oxoglutarate <=> Glyoxylate + L-Glutamate
Equation
Reaction class
RC00006  C00025_C00026
RC00018  C00037_C00048
Enzyme
2.6.1.4         2.6.1.44
Pathway
rn00260  Glycine, serine and threonine metabolism
rn00630  Glyoxylate and dicarboxylate metabolism
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01200  Carbon metabolism
Module
M00532  Photorespiration
Orthology
K00827  alanine-glyoxylate transaminase / (R)-3-amino-2-methylpropionate-pyruvate transaminase [EC:2.6.1.44 2.6.1.40]
K00830  alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase [EC:2.6.1.44 2.6.1.45 2.6.1.51]
K14272  glutamate--glyoxylate aminotransferase [EC:2.6.1.4 2.6.1.2 2.6.1.44]
Other DBs
RHEA: 14092
LinkDB

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