KEGG   ORTHOLOGY: K14461
Entry
K14461                      KO                                     
Symbol
NPC1L1
Name
Niemann-Pick C1-like protein 1
Pathway
map04975  Fat digestion and absorption
Brite
KEGG Orthology (KO) [BR:ko00001]
 09150 Organismal Systems
  09154 Digestive system
   04975 Fat digestion and absorption
    K14461  NPC1L1; Niemann-Pick C1-like protein 1
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters
    K14461  NPC1L1; Niemann-Pick C1-like protein 1
Transporters [BR:ko02000]
 Solute carrier family (SLC)
  SLC65: NPC-type cholesterol transporter
   K14461  NPC1L1; Niemann-Pick C1-like protein 1
Other DBs
TC: 2.A.6.6.6
Genes
HSA: 29881(NPC1L1)
PTR: 463381(NPC1L1)
PPS: 100977825(NPC1L1)
GGO: 101141407(NPC1L1)
PON: 100458187(NPC1L1)
NLE: 100590536(NPC1L1)
MCC: 699235(NPC1L1)
MCF: 102124143(NPC1L1)
CSAB: 103227363(NPC1L1)
CATY: 105596906(NPC1L1)
PANU: 101007992(NPC1L1)
TGE: 112620935(NPC1L1)
RRO: 104671148(NPC1L1)
RBB: 108529385(NPC1L1)
TFN: 117073307(NPC1L1)
PTEH: 111552319(NPC1L1)
CJC: 100391007(NPC1L1)
SBQ: 101052583(NPC1L1)
CSYR: 103251945(NPC1L1)
MMUR: 105870644(NPC1L1)
LCAT: 123647611(NPC1L1)
OGA: 100965324(NPC1L1)
MMU: 237636(Npc1l1)
MCAL: 110305663(Npc1l1)
MPAH: 110330743(Npc1l1)
RNO: 432367(Npc1l1)
MCOC: 116068900(Npc1l1)
MUN: 110546121(Npc1l1)
CGE: 100763971(Npc1l1)
MAUA: 101840157(Npc1l1)
PLEU: 114694097(Npc1l1)
MORG: 121459453(Npc1l1)
AAMP: 119827127(Npc1l1)
NGI: 103734986(Npc1l1)
HGL: 101718169(Npc1l1)
CPOC: 100716804(Npc1l1)
CCAN: 109686601(Npc1l1)
DORD: 105998262(Npc1l1)
DSP: 122128077(Npc1l1)
NCAR: 124990862
OCU: 100009042(NPC1L1)
OPI: 101534536(NPC1L1)
TUP: 102493644(NPC1L1)
CFA: 610398(NPC1L1)
CLUD: 112650789(NPC1L1)
VVP: 112911694(NPC1L1)
VLG: 121489099(NPC1L1)
AML: 100478497(NPC1L1)
UMR: 103674681(NPC1L1)
UAH: 113257804(NPC1L1)
UAR: 123789463(NPC1L1)
ELK: 111157060
LLV: 125080734
MPUF: 101682629(NPC1L1)
ORO: 101386640(NPC1L1)
EJU: 114202285(NPC1L1)
ZCA: 113911137(NPC1L1)
MLX: 118024578(NPC1L1)
FCA: 101099108(NPC1L1)
PYU: 121016947(NPC1L1)
PBG: 122487631(NPC1L1)
PTG: 102964566(NPC1L1)
PPAD: 109267918(NPC1L1)
AJU: 106968233(NPC1L1)
HHV: 120238921(NPC1L1)
BTA: 539550(NPC1L1)
BOM: 102281269(NPC1L1)
BIU: 109557539(NPC1L1)
BBUB: 102394108(NPC1L1)
CHX: 102184874(NPC1L1)
OAS: 101118355(NPC1L1)
ODA: 120877495(NPC1L1)
CCAD: 122437788(NPC1L1)
SSC: 100515982(NPC1L1)
CFR: 102506093(NPC1L1)
CBAI: 105080690(NPC1L1)
CDK: 105092347(NPC1L1)
VPC: 102536637(NPC1L1)
BACU: 103004449(NPC1L1)
LVE: 103083362(NPC1L1)
OOR: 101277149(NPC1L1)
DLE: 111184518(NPC1L1)
PCAD: 102979951(NPC1L1)
PSIU: 116759335(NPC1L1)
ECB: 100065105(NPC1L1)
EPZ: 103554953(NPC1L1)
EAI: 106822959(NPC1L1)
MYB: 102260685(NPC1L1)
MYD: 102757732(NPC1L1)
MMYO: 118665866(NPC1L1)
MLF: 102427415(NPC1L1)
MNA: 107542051(NPC1L1)
PKL: 118717982(NPC1L1)
HAI: 109373008(NPC1L1)
DRO: 112306910(NPC1L1)
SHON: 118983467(NPC1L1)
AJM: 119052891(NPC1L1)
PDIC: 114490224(NPC1L1)
PHAS: 123811557(NPC1L1)
MMF: 118619880(NPC1L1)
RFQ: 117012148(NPC1L1)
PALE: 102889482(NPC1L1)
PGIG: 120589560(NPC1L1)
PVP: 105308763(NPC1L1)
RAY: 107512389(NPC1L1)
MJV: 108395962(NPC1L1)
TOD: 119237615(NPC1L1)
SARA: 101537227(NPC1L1)
TMU: 101353340
DNM: 101446599(NPC1L1)
MDO: 100030165(NPC1L1)
GAS: 123235024(NPC1L1)
SHR: 100918685(NPC1L1)
PCW: 110206568(NPC1L1)
OAA: 100089021(NPC1L1)
PCOC: 116237690
CJO: 107323594(NPC1L1)
ACYG: 106048901(NPC1L1)
AFUL: 116499304(NPC1L1)
TGU: 115498089(NPC1L1)
LSR: 110478264(NPC1L1)
PMOA: 120499153(NPC1L1)
OTC: 121334125(NPC1L1)
PRUF: 121352739(NPC1L1)
PHI: 102110106(NPC1L1)
PMAJ: 107199325
ETL: 114066451(NPC1L1)
FPG: 101916519
CLV: 102097787(NPC1L1)
ACHC: 115349854
AAM: 106486481
AROW: 112975339(NPC1L1)
NPD: 112950224(NPC1L1)
ASN: 102370832(NPC1L1)
AMJ: 102576666(NPC1L1)
CPOO: 109313275(NPC1L1)
CMY: 102933372(NPC1L1)
CPIC: 101953743(NPC1L1)
TST: 117871755(NPC1L1)
CABI: 116830721(NPC1L1)
MRV: 120399665
PVT: 110072195(NPC1L1)
SUND: 121933970(NPC1L1)
PBI: 103065603(NPC1L1)
PMUR: 107283248(NPC1L1)
TSR: 106556878(NPC1L1)
PGUT: 117673312(NPC1L1)
VKO: 123016779(NPC1L1)
PMUA: 114602717(NPC1L1)
ZVI: 118087004(NPC1L1)
GJA: 107118735(NPC1L1)
STOW: 125441517(NPC1L1)
XLA: 108711582(npc1l1.L) 108712289(npc1l1.S)
XTR: 100487339(npc1l1)
NPR: 108796068(NPC1L1) 108801209
RTEM: 120933058(NPC1L1)
BBUF: 120986180(NPC1L1)
BGAR: 122927387(NPC1L1)
DRE: 100616532(npc1l1)
SRX: 107753092(npc1l1)
SANH: 107703134(npc1l1)
SGH: 107554417(npc1l1)
CCAR: 109100782(npc1l1)
PPRM: 120473525(npc1l1)
MAMB: 125280098(npc1l1)
IPU: 108265750(npc1l1)
PHYP: 113546106(npc1l1)
SMEO: 124400212(npc1l1)
TFD: 113645910(npc1l1)
AMEX: 103040688(npc1l1)
EEE: 113588673(npc1l1)
TRU: 101061759(npc1l1)
LCO: 104930661(npc1l1)
NCC: 104948494(npc1l1)
CGOB: 115013348(npc1l1)
ELY: 117253033(npc1l1)
EFO: 125890845(npc1l1)
PLEP: 121944346(npc1l1)
SLUC: 116057284(npc1l1)
PFLV: 114556318(npc1l1)
GAT: 120830318(npc1l1)
PPUG: 119224656(npc1l1)
MSAM: 119891130(npc1l1)
CUD: 121509345(npc1l1)
ALAT: 119019129(npc1l1)
MZE: 101465425
ONL: 100691090(npc1l1)
OAU: 116324276(npc1l1)
OLA: 101160914(npc1l1)
OML: 112148803(npc1l1)
XMA: 102233351(npc1l1)
XCO: 114153969(npc1l1)
XHE: 116729141(npc1l1)
PRET: 103470594(npc1l1)
PFOR: 103146657(npc1l1)
PLAI: 106949581(npc1l1)
PMEI: 106933187(npc1l1)
GAF: 122828420(npc1l1)
CVG: 107092753(npc1l1)
CTUL: 119784967(npc1l1)
GMU: 124877348(npc1l1)
NFU: 107393669(npc1l1)
KMR: 108236594(npc1l1)
ALIM: 106516715(npc1l1)
NWH: 119413632(npc1l1)
AOCE: 111575038(npc1l1)
MCEP: 125011992(npc1l1)
POV: 109641089(npc1l1)
SSEN: 122770145(npc1l1)
HHIP: 117768460(npc1l1)
HSP: 118115147(npc1l1)
LCF: 108878225(npc1l1)
SDU: 111226536(npc1l1)
SLAL: 111644989(npc1l1)
XGL: 120805292(npc1l1)
HCQ: 109510635(npc1l1)
BPEC: 110169840(npc1l1)
MALB: 109954829(npc1l1)
BSPL: 114861915(npc1l1)
SASA: 106585168(npc1l1)
OTW: 112248786(npc1l1)
OMY: 110525937(npc1l1)
OGO: 124034105(npc1l1)
ONE: 115111843(npc1l1)
SALP: 111974545(npc1l1)
SNH: 120044459(npc1l1)
CCLU: 121585091(npc1l1)
ELS: 105014405(npc1l1)
SFM: 108940398(npc1l1)
PKI: 111857569(npc1l1)
AANG: 118206857(npc1l1) 118212510
LOC: 102697857(npc1l1)
LCM: 102365493(NPC1L1)
CMK: 103187795(npc1l1)
CIN: 778978
 » show all
Reference
  Authors
Davies JP, Levy B, Ioannou YA
  Title
Evidence for a Niemann-pick C (NPC) gene family: identification and characterization of NPC1L1.
  Journal
Genomics 65:137-45 (2000)
DOI:10.1006/geno.2000.6151
  Sequence
[hsa:29881]
Reference
  Authors
Jia L, Betters JL, Yu L
  Title
Niemann-pick C1-like 1 (NPC1L1) protein in intestinal and hepatic cholesterol transport.
  Journal
Annu Rev Physiol 73:239-59 (2011)
DOI:10.1146/annurev-physiol-012110-142233
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