KEGG   ORTHOLOGY: K14520
Entry
K14520                      KO                                     
Symbol
hapE
Name
4-hydroxyacetophenone monooxygenase [EC:1.14.13.84]
Pathway
map00363  Bisphenol degradation
map01100  Metabolic pathways
map01120  Microbial metabolism in diverse environments
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00363 Bisphenol degradation
    K14520  hapE; 4-hydroxyacetophenone monooxygenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.13.84  4-hydroxyacetophenone monooxygenase
     K14520  hapE; 4-hydroxyacetophenone monooxygenase
Other DBs
RN: R06892
GO: 0033767
Genes
PALK: PSAKL28_30880
GAG: Glaag_3898
GPS: C427_5372
HJA: BST95_01710
HALC: EY643_18055
BXE: Bxe_C0316
BXB: DR64_8118
BGE: BC1002_5820
PVE: UC34_06840
BHZ: ACR54_00614(hapE_3)
BPDZ: BBN53_18555
AXY: AXYL_05757
ADY: HLG70_25065
HYB: Q5W_23445
DIH: G7047_24405
MESO: BSQ44_24815
RHI: NGR_a03290
SAME: SAMCFNEI73_pB0414
ESJ: SJ05684_a39130
REL: REMIM1_PE00364
REI: IE4771_PB00135
RTR: RTCIAT899_PB00970
RGA: RGR602_PB00162
RJG: CCGE525_34750
BJA: bll3180(bll3180)
BJU: BJ6T_65720
BJP: RN69_31860
BRS: S23_48170
BRC: BCCGELA001_14335
BIC: LMTR13_10065
BRK: CWS35_32470
BOT: CIT37_37580
BRQ: CIT40_10485
BGQ: X265_25110
BGZ: XH91_23220
BSYM: CIT39_09530
BBET: F8237_04135
BARH: WN72_17480
BVZ: BRAD3257_1812
BEL: BE61_38490
BDG: LPJ38_18855
BSEP: HAP48_0048135
BQB: J4P68_0007355
BBAN: J4G43_018415
NTD: EGO55_02615 EGO55_04725 EGO55_13890 EGO55_14155 EGO55_18115
MMED: Mame_02139(hapE)
RBM: TEF_09540 TEF_14660
PZU: PHZ_c1807
PHB: HYN04_07140
SMED: JNX03_16175
RID: RIdsm_01107(hapE_3)
NAR: Saro_2452
NPN: JI59_09905 JI59_12755 JI59_17720 JI59_21965
NOV: TQ38_027485 TQ38_027690
NOT: C7W88_20535
NOR: FA702_19610
NOG: GKE62_01765
SPHP: LH20_19445
STER: AOA14_07210
SWI: Swit_2012
SPHD: HY78_15455
SPHM: G432_19880
SMY: BJP26_18750
SPKC: KC8_02285 KC8_02340
SJP: SJA_C2-05090
SINB: SIDU_10910
SCH: Sphch_3468
SPMI: K663_17836 K663_17946 K663_18141 K663_19768
SPHB: EP837_01273(hapE) EP837_01276 EP837_03238 EP837_03267 EP837_03277 EP837_03339 EP837_03509
SPHT: K426_23414
SPPH: KFK14_08115
SPHJ: BSL82_08780
PALG: HFP57_16470
SMIC: SmB9_21780 SmB9_37040
SAND: H3309_16645
POQ: KZX46_02635 KZX46_17875
PMEA: KTC28_16080
AEP: AMC99_02079
ALH: G6N82_11870
EFV: CHH26_10020
ERR: DVR09_13385
TMO: TMO_b0525
MPA: MAP_1441 MAP_1620
MAO: MAP4_2219 MAP4_2403
MAVI: RC58_11040 RC58_11945
MAVU: RE97_11050 RE97_11955
MAV: MAV_2805
MIT: OCO_26400 OCO_28650
MIA: OCU_26250 OCU_28510
MID: MIP_03698 MIP_04049
MYO: OEM_24870 OEM_27100
MCHI: AN480_10590 AN480_13895
MIR: OCQ_24960 OCQ_27230
MMAL: CKJ54_11925 CKJ54_13020
MMAN: MMAN_10250 MMAN_12600
MSA: Mycsm_03363
MMI: MMAR_2622 MMAR_2789
MMAE: MMARE11_25410 MMARE11_27110
MLI: MULP_02355
MPSE: MPSD_28800
MSHO: MSHO_39150 MSHO_41990
MMC: Mmcs_0310 Mmcs_1518 Mmcs_2740
MKM: Mkms_0320 Mkms_1541 Mkms_2784
MJL: Mjls_2770
MMM: W7S_12815 W7S_13885
MKN: MKAN_00815
MYV: G155_01790 G155_04185
MYE: AB431_01805 AB431_15145
MDX: BTO20_34235
MSHG: MSG_02684 MSG_04454
MFJ: MFLOJ_05450 MFLOJ_51620 MFLOJ_54900
MSTO: MSTO_06750 MSTO_59330
MSIM: MSIM_50750
MSAK: MSAS_07860
MKU: I2456_13765
MLW: MJO58_12975 MJO58_14125 MJO58_19375
MGRO: FZ046_20310
MXE: MYXE_38750 MYXE_42320
MNV: MNVI_26500
MPAG: C0J29_01040 C0J29_16070 C0J29_19310
MNM: MNVM_19270 MNVM_28240
MGOR: H0P51_00695 H0P51_09335 H0P51_15105 H0P51_17885
MCOO: MCOO_26190 MCOO_43040
MBAI: MB901379_02580(hapE_5)
MSEO: MSEO_12650 MSEO_14970
MHEK: JMUB5695_03800
MGAU: MGALJ_16320 MGALJ_22920
MLJ: MLAC_18560
MBRD: MBRA_05320 MBRA_21050
MSHJ: MSHI_13020
MMAM: K3U93_12890 K3U93_16480
MSPG: F6B93_11555 F6B93_12080
MOT: LTS72_10260
MPAA: MKK62_02875 MKK62_19500 MKK62_25885
MSM: MSMEG_2884
MSG: MSMEI_2810
MSB: LJ00_14345
MSN: LI99_14350
MSH: LI98_14355
MVA: Mvan_1842 Mvan_2883
MGI: Mflv_4506 Mflv_4557
MSP: Mspyr1_39050 Mspyr1_39570
MCB: Mycch_1506 Mycch_1583
MNE: D174_03215
MYN: MyAD_03140
MFT: XA26_03850 XA26_07900
MPHL: MPHLCCUG_01020(hapE_2) MPHLCCUG_02619(hapE_6)
MVQ: MYVA_1658 MYVA_1697 MYVA_4982
MLL: B1R94_01420 B1R94_12415
MRH: MycrhN_4918
MTHN: 4412656_00667(hapE_1) 4412656_00952(hapE_2)
MHAS: MHAS_00653(hapE_1) MHAS_02465(hapE_2)
MDU: MDUV_26540 MDUV_26740
MCHT: MCHIJ_02010 MCHIJ_02120 MCHIJ_08790 MCHIJ_12830
MAUU: NCTC10437_01662(hapE_4) NCTC10437_01669(hapE_5) NCTC10437_02731(hapE_9)
MMAG: MMAD_29640
MMOR: MMOR_00710 MMOR_10050 MMOR_26730 MMOR_33780 MMOR_47920
MFX: MFAL_09770 MFAL_26200
MAIC: MAIC_26710 MAIC_53440
MIJ: MINS_06790 MINS_26620
MALV: MALV_29370 MALV_32190
MTY: MTOK_12030
MPSC: MPSYJ_47990
MARZ: MARA_09020
MGAD: MGAD_01030 MGAD_08510
MHEV: MHEL_19100 MHEL_50050 MHEL_59170
MSAR: MSAR_18520 MSAR_41410
MANY: MANY_43550
MAUB: MAUB_06770
MPOF: MPOR_21690
MPHU: MPHO_05910
MMUC: C1S78_015375 C1S78_019285
MMAT: MMAGJ_17560
MBOK: MBOE_16070 MBOE_19840
MFG: K6L26_27725 K6L26_29615
MSEI: MSEDJ_42750
MFLV: NCTC10271_02178(hapE_2)
MCEE: MCEL_06010 MCEL_41620
MMON: EWR22_01655 EWR22_07725 EWR22_14555
MHOL: K3U96_00470 K3U96_07055 K3U96_09595 K3U96_12435
MSEN: K3U95_01840
MPAE: K0O64_01410 K0O64_14620
MRF: MJO55_08255
MDF: K0O62_02210 K0O62_05035 K0O62_11570 K0O62_15825
MCRO: MI149_01945 MI149_15475
MKR: MKOR_36470
MPAK: MIU77_08125
MCHE: BB28_00510
MSAL: DSM43276_00081(hapE_2)
MJD: JDM601_3248 JDM601_4258
MTER: 4434518_03234(hapE_6)
MMIN: MMIN_06780 MMIN_09430
MHIB: MHIB_23920 MHIB_26590
MHER: K3U94_18290
MVM: MJO54_18455
CCYC: SCMU_01920 SCMU_38690
NFA: NFA_33700
NFR: ERS450000_00683(hapE_3)
NNO: NONO_c26450 NONO_c26620 NONO_c26820 NONO_c27210
NOZ: DMB37_03490
RHA: RHA1_ro05396
REY: O5Y_27880
RQI: C1M55_29730
ROP: ROP_25260
RHB: NY08_34
RFA: A3L23_03397(hapE_2)
RHS: A3Q41_04847(hapE_2)
RRZ: CS378_11525
RHU: A3Q40_00667(hapE_1)
RHOD: AOT96_09385
RCR: NCTC10994_03316(hapE_4)
RKO: JWS14_03735 JWS14_13900 JWS14_43780 JWS14_44120 JWS14_44420
ROZ: CBI38_08630 CBI38_34625
RPSK: JWS13_12455 JWS13_31690
REQ: REQ_13640 REQ_45280
GOR: KTR9_0546 KTR9_2191 KTR9_3188
GTA: BCM27_04875 BCM27_11715 BCM27_16285 BCM27_19035
GRU: GCWB2_13960(hapE4)
GOM: D7316_04266(hapE_1) D7316_04655(hapE_2)
GAV: C5O27_14130
GOD: GKZ92_12830
GPD: GII33_20030
GJI: H1R19_00410 H1R19_10915 H1R19_19295
GHN: MVF96_11115
GAMI: IHQ52_16570
GMG: NWF22_20955
DIZ: CT688_05610
TOY: FO059_17465
SCAD: DN051_01765
SALJ: SMD11_0682(hapE)
SPLA: CP981_11500
MIO: AOA12_02825 AOA12_13430 AOA12_19215
MRN: K8F61_04945
LEU: Leucomu_12905
ARZ: AUT26_19680 AUT26_19745
ARX: ARZXY2_4020(hapE)
ARTP: E5206_14925 E5206_18210
AJG: KKR91_13970
GLU: F0M17_15875 F0M17_15940
GPR: JQN66_16310 JQN66_16375
PAEY: KUF55_15805 KUF55_16730
AEZ: C3E78_14050
NOA: BKM31_13265
FRI: FraEuI1c_2106 FraEuI1c_3128 FraEuI1c_3915
SACG: FDZ84_29950 FDZ84_37130
AMYY: YIM_36680(hapE5) YIM_36800(hapE6)
AACD: LWP59_17040
PDX: Psed_2079 Psed_2677
PAUT: Pdca_05840
PBRO: HOP40_17195
PPEL: H6H00_16815 H6H00_19165
SSYI: EKG83_16290 EKG83_27315
ABAI: IMCC26256_11166 IMCC26256_111801
BSOL: FSW04_06275 FSW04_06440 FSW04_20620
AYM: YM304_37530
ATQ: GH723_04715
AQZ: KSP35_01975
IAM: HC251_23265
TBH: Tbon_00650
AG: AAK54073(hapA)
 » show all
Reference
PMID:11322873
  Authors
Kamerbeek NM, Moonen MJ, Van Der Ven JG, Van Berkel WJ, Fraaije MW, Janssen DB
  Title
4-Hydroxyacetophenone monooxygenase from Pseudomonas fluorescens ACB. A novel flavoprotein catalyzing Baeyer-Villiger oxidation of aromatic compounds.
  Journal
Eur J Biochem 268:2547-57 (2001)
DOI:10.1046/j.1432-1327.2001.02137.x
  Sequence
[ag:AAK54073]
LinkDB

KEGG   ENZYME: 1.14.13.84
Entry
EC 1.14.13.84               Enzyme                                 
Name
4-hydroxyacetophenone monooxygenase;
HAPMO
Class
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
Sysname
(4-hydroxyphenyl)ethan-1-one,NADPH:oxygen oxidoreductase (ester-forming)
Reaction(IUBMB)
(4-hydroxyphenyl)ethan-1-one + NADPH + H+ + O2 = 4-hydroxyphenyl acetate + NADP+ + H2O [RN:R06892]
Reaction(KEGG)
R06892
Substrate
(4-hydroxyphenyl)ethan-1-one [CPD:C10700];
NADPH [CPD:C00005];
H+ [CPD:C00080];
O2 [CPD:C00007]
Product
4-hydroxyphenyl acetate [CPD:C13636];
NADP+ [CPD:C00006];
H2O [CPD:C00001]
Comment
Contains FAD. The enzyme from Pseudomonas fluorescens ACB catalyses the conversion of a wide range of acetophenone derivatives. Highest activity occurs with compounds bearing an electron-donating substituent at the para position of the aromatic ring [1]. In the absence of substrate, the enzyme can act as an NAD(P)H oxidase (EC 1.6.3.1).
History
EC 1.14.13.84 created 2004
Pathway
ec00363  Bisphenol degradation
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K14520  4-hydroxyacetophenone monooxygenase
Genes
PALK: PSAKL28_30880
GAG: Glaag_3898
GPS: C427_5372
HJA: BST95_01710
HALC: EY643_18055
BXE: Bxe_C0316
BXB: DR64_8118
BGE: BC1002_5820
PVE: UC34_06840
BHZ: ACR54_00614(hapE_3)
BPDZ: BBN53_18555
AXY: AXYL_05757
ADY: HLG70_25065
HYB: Q5W_23445
DIH: G7047_24405
MESO: BSQ44_24815
RHI: NGR_a03290
SAME: SAMCFNEI73_pB0414
ESJ: SJ05684_a39130
REL: REMIM1_PE00364
REI: IE4771_PB00135
RTR: RTCIAT899_PB00970
RGA: RGR602_PB00162
RJG: CCGE525_34750
BJA: bll3180(bll3180)
BJU: BJ6T_65720
BJP: RN69_31860
BRS: S23_48170
BRC: BCCGELA001_14335
BIC: LMTR13_10065
BRK: CWS35_32470
BOT: CIT37_37580
BRQ: CIT40_10485
BGQ: X265_25110
BGZ: XH91_23220
BSYM: CIT39_09530
BBET: F8237_04135
BARH: WN72_17480
BVZ: BRAD3257_1812
BEL: BE61_38490
BDG: LPJ38_18855
BSEP: HAP48_0048135
BQB: J4P68_0007355
BBAN: J4G43_018415
NTD: EGO55_02615 EGO55_04725 EGO55_13890 EGO55_14155 EGO55_18115
MMED: Mame_02139(hapE)
RBM: TEF_09540 TEF_14660
PZU: PHZ_c1807
PHB: HYN04_07140
SMED: JNX03_16175
RID: RIdsm_01107(hapE_3)
NAR: Saro_2452
NPN: JI59_09905 JI59_12755 JI59_17720 JI59_21965
NOV: TQ38_027485 TQ38_027690
NOT: C7W88_20535
NOR: FA702_19610
NOG: GKE62_01765
SPHP: LH20_19445
STER: AOA14_07210
SWI: Swit_2012
SPHD: HY78_15455
SPHM: G432_19880
SMY: BJP26_18750
SPKC: KC8_02285 KC8_02340
SJP: SJA_C2-05090
SINB: SIDU_10910
SCH: Sphch_3468
SPMI: K663_17836 K663_17946 K663_18141 K663_19768
SPHB: EP837_01273(hapE) EP837_01276 EP837_03238 EP837_03267 EP837_03277 EP837_03339 EP837_03509
SPHT: K426_23414
SPPH: KFK14_08115
SPHJ: BSL82_08780
PALG: HFP57_16470
SMIC: SmB9_21780 SmB9_37040
SAND: H3309_16645
POQ: KZX46_02635 KZX46_17875
PMEA: KTC28_16080
AEP: AMC99_02079
ALH: G6N82_11870
EFV: CHH26_10020
ERR: DVR09_13385
TMO: TMO_b0525
MPA: MAP_1441 MAP_1620
MAO: MAP4_2219 MAP4_2403
MAVI: RC58_11040 RC58_11945
MAVU: RE97_11050 RE97_11955
MAV: MAV_2805
MIT: OCO_26400 OCO_28650
MIA: OCU_26250 OCU_28510
MID: MIP_03698 MIP_04049
MYO: OEM_24870 OEM_27100
MCHI: AN480_10590 AN480_13895
MIR: OCQ_24960 OCQ_27230
MMAL: CKJ54_11925 CKJ54_13020
MMAN: MMAN_10250 MMAN_12600
MSA: Mycsm_03363
MMI: MMAR_2622 MMAR_2789
MMAE: MMARE11_25410 MMARE11_27110
MLI: MULP_02355
MPSE: MPSD_28800
MSHO: MSHO_39150 MSHO_41990
MMC: Mmcs_0310 Mmcs_1518 Mmcs_2740
MKM: Mkms_0320 Mkms_1541 Mkms_2784
MJL: Mjls_2770
MMM: W7S_12815 W7S_13885
MKN: MKAN_00815
MYV: G155_01790 G155_04185
MYE: AB431_01805 AB431_15145
MDX: BTO20_34235
MSHG: MSG_02684 MSG_04454
MFJ: MFLOJ_05450 MFLOJ_51620 MFLOJ_54900
MSTO: MSTO_06750 MSTO_59330
MSIM: MSIM_50750
MSAK: MSAS_07860
MKU: I2456_13765
MLW: MJO58_12975 MJO58_14125 MJO58_19375
MGRO: FZ046_20310
MXE: MYXE_38750 MYXE_42320
MNV: MNVI_26500
MPAG: C0J29_01040 C0J29_16070 C0J29_19310
MNM: MNVM_19270 MNVM_28240
MGOR: H0P51_00695 H0P51_09335 H0P51_15105 H0P51_17885
MCOO: MCOO_26190 MCOO_43040
MBAI: MB901379_02580(hapE_5)
MSEO: MSEO_12650 MSEO_14970
MHEK: JMUB5695_03800
MGAU: MGALJ_16320 MGALJ_22920
MLJ: MLAC_18560
MBRD: MBRA_05320 MBRA_21050
MSHJ: MSHI_13020
MMAM: K3U93_12890 K3U93_16480
MSPG: F6B93_11555 F6B93_12080
MOT: LTS72_10260
MPAA: MKK62_02875 MKK62_19500 MKK62_25885
MSM: MSMEG_2884
MSG: MSMEI_2810
MSB: LJ00_14345
MSN: LI99_14350
MSH: LI98_14355
MVA: Mvan_1842 Mvan_2883
MGI: Mflv_4506 Mflv_4557
MSP: Mspyr1_39050 Mspyr1_39570
MCB: Mycch_1506 Mycch_1583
MNE: D174_03215
MYN: MyAD_03140
MFT: XA26_03850 XA26_07900
MPHL: MPHLCCUG_01020(hapE_2) MPHLCCUG_02619(hapE_6)
MVQ: MYVA_1658 MYVA_1697 MYVA_4982
MLL: B1R94_01420 B1R94_12415
MRH: MycrhN_4918
MTHN: 4412656_00667(hapE_1) 4412656_00952(hapE_2)
MHAS: MHAS_00653(hapE_1) MHAS_02465(hapE_2)
MDU: MDUV_26540 MDUV_26740
MCHT: MCHIJ_02010 MCHIJ_02120 MCHIJ_08790 MCHIJ_12830
MAUU: NCTC10437_01662(hapE_4) NCTC10437_01669(hapE_5) NCTC10437_02731(hapE_9)
MMAG: MMAD_29640
MMOR: MMOR_00710 MMOR_10050 MMOR_26730 MMOR_33780 MMOR_47920
MFX: MFAL_09770 MFAL_26200
MAIC: MAIC_26710 MAIC_53440
MIJ: MINS_06790 MINS_26620
MALV: MALV_29370 MALV_32190
MTY: MTOK_12030
MPSC: MPSYJ_47990
MARZ: MARA_09020
MGAD: MGAD_01030 MGAD_08510
MHEV: MHEL_19100 MHEL_50050 MHEL_59170
MSAR: MSAR_18520 MSAR_41410
MANY: MANY_43550
MAUB: MAUB_06770
MPOF: MPOR_21690
MPHU: MPHO_05910
MMUC: C1S78_015375 C1S78_019285
MMAT: MMAGJ_17560
MBOK: MBOE_16070 MBOE_19840
MFG: K6L26_27725 K6L26_29615
MSEI: MSEDJ_42750
MFLV: NCTC10271_02178(hapE_2)
MCEE: MCEL_06010 MCEL_41620
MMON: EWR22_01655 EWR22_07725 EWR22_14555
MHOL: K3U96_00470 K3U96_07055 K3U96_09595 K3U96_12435
MSEN: K3U95_01840
MPAE: K0O64_01410 K0O64_14620
MRF: MJO55_08255
MDF: K0O62_02210 K0O62_05035 K0O62_11570 K0O62_15825
MCRO: MI149_01945 MI149_15475
MKR: MKOR_36470
MPAK: MIU77_08125
MCHE: BB28_00510
MSAL: DSM43276_00081(hapE_2)
MJD: JDM601_3248 JDM601_4258
MTER: 4434518_03234(hapE_6)
MMIN: MMIN_06780 MMIN_09430
MHIB: MHIB_23920 MHIB_26590
MHER: K3U94_18290
MVM: MJO54_18455
CCYC: SCMU_01920 SCMU_38690
NFA: NFA_33700
NFR: ERS450000_00683(hapE_3)
NNO: NONO_c26450 NONO_c26620 NONO_c26820 NONO_c27210
NOZ: DMB37_03490
RHA: RHA1_ro05396
REY: O5Y_27880
RQI: C1M55_29730
ROP: ROP_25260
RHB: NY08_34
RFA: A3L23_03397(hapE_2)
RHS: A3Q41_04847(hapE_2)
RRZ: CS378_11525
RHU: A3Q40_00667(hapE_1)
RHOD: AOT96_09385
RCR: NCTC10994_03316(hapE_4)
RKO: JWS14_03735 JWS14_13900 JWS14_43780 JWS14_44120 JWS14_44420
ROZ: CBI38_08630 CBI38_34625
RPSK: JWS13_12455 JWS13_31690
REQ: REQ_13640 REQ_45280
GOR: KTR9_0546 KTR9_2191 KTR9_3188
GTA: BCM27_04875 BCM27_11715 BCM27_16285 BCM27_19035
GRU: GCWB2_13960(hapE4)
GOM: D7316_04266(hapE_1) D7316_04655(hapE_2)
GAV: C5O27_14130
GOD: GKZ92_12830
GPD: GII33_20030
GJI: H1R19_00410 H1R19_10915 H1R19_19295
GHN: MVF96_11115
GAMI: IHQ52_16570
GMG: NWF22_20955
DIZ: CT688_05610
TOY: FO059_17465
SCAD: DN051_01765
SALJ: SMD11_0682(hapE)
SPLA: CP981_11500
MIO: AOA12_02825 AOA12_13430 AOA12_19215
MRN: K8F61_04945
LEU: Leucomu_12905
ARZ: AUT26_19680 AUT26_19745
ARX: ARZXY2_4020(hapE)
ARTP: E5206_14925 E5206_18210
AJG: KKR91_13970
GLU: F0M17_15875 F0M17_15940
GPR: JQN66_16310 JQN66_16375
PAEY: KUF55_15805 KUF55_16730
AEZ: C3E78_14050
NOA: BKM31_13265
FRI: FraEuI1c_2106 FraEuI1c_3128 FraEuI1c_3915
SACG: FDZ84_29950 FDZ84_37130
AMYY: YIM_36680(hapE5) YIM_36800(hapE6)
AACD: LWP59_17040
PDX: Psed_2079 Psed_2677
PAUT: Pdca_05840
PBRO: HOP40_17195
PPEL: H6H00_16815 H6H00_19165
SSYI: EKG83_16290 EKG83_27315
ABAI: IMCC26256_11166 IMCC26256_111801
BSOL: FSW04_06275 FSW04_06440 FSW04_20620
AYM: YM304_37530
ATQ: GH723_04715
AQZ: KSP35_01975
IAM: HC251_23265
TBH: Tbon_00650
 » show all
Reference
1  [PMID:11322873]
  Authors
Kamerbeek NM, Moonen MJ, Van Der Ven JG, Van Berkel WJ, Fraaije MW, Janssen DB
  Title
4-Hydroxyacetophenone monooxygenase from Pseudomonas fluorescens ACB. A novel flavoprotein catalyzing Baeyer-Villiger oxidation of aromatic compounds.
  Journal
Eur J Biochem 268:2547-57 (2001)
DOI:10.1046/j.1432-1327.2001.02137.x
  Sequence
[ag:AAK54073]
Reference
2  [PMID:12514023]
  Authors
Kamerbeek NM, Olsthoorn AJ, Fraaije MW, Janssen DB.
  Title
Substrate specificity and enantioselectivity of 4-hydroxyacetophenone monooxygenase.
  Journal
Appl Environ Microbiol 69:419-26 (2003)
DOI:10.1128/AEM.69.1.419-426.2003
  Sequence
[ag:AAK54073]
Other DBs
ExplorEnz - The Enzyme Database: 1.14.13.84
IUBMB Enzyme Nomenclature: 1.14.13.84
ExPASy - ENZYME nomenclature database: 1.14.13.84
BRENDA, the Enzyme Database: 1.14.13.84
CAS: 156621-13-5
LinkDB

KEGG   REACTION: R06892
Entry
R06892                      Reaction                               
Name
(4-hydroxyphenyl)ethan-1-one,NADPH:oxygen oxidoreductase (ester-forming)
Definition
4'-Hydroxyacetophenone + NADPH + H+ + Oxygen <=> 4-Hydroxyphenyl acetate + NADP+ + H2O
Equation
C10700 + C00005 + C00080 + C00007 <=> C13636 + C00006 + C00001
Reaction class
RC00001  C00005_C00006
RC01644  C10700_C13636
Enzyme
1.14.13.84
Pathway
rn00363  Bisphenol degradation
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
Orthology
K14520  4-hydroxyacetophenone monooxygenase [EC:1.14.13.84]
Other DBs
RHEA: 22919
LinkDB

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