Entry
Name
S-linalool synthase;
LIS;
Lis;
3S-linalool synthase
Class
Lyases;
Carbon-oxygen lyases;
Acting on phosphates
BRITE hierarchy
Sysname
geranyl-diphosphate diphosphate-lyase [(3S)-linalool-forming]
Reaction(IUBMB)
geranyl diphosphate + H2O = (3S)-linalool + diphosphate [RN:
R07631 ]
Reaction(KEGG)
Substrate
Product
Comment
Requires Mn2+ or Mg2+ for activity. Neither (S)- nor (R)-linalyl diphosphate can act as substrate for the enzyme from the flower Clarkia breweri [1]. Unlike many other monoterpene synthases, only a single product, (3S)-linalool, is formed.
History
EC 4.2.3.25 created 2006
Pathway
ec01110 Biosynthesis of secondary metabolites
Orthology
Genes
THJ : 104809528 104818931 104818943
ATS : 109736851 109765288 109765297
TDC : 119314480 119315591 119315592 119318901 119320186 119320773 119320774 119320901 119321507 119321735 119321939 119322945 119324776 119325690 119326303 119342952 119344547 119352067 119365784
TAES : 123039445 123054688 123130192 123130193 123130194 123130195 123130196 123133528 123133529 123133531 123133532 123133533 123135858 123138836 123138838 123138839 123138844 123138847 123138848 123139433 123140864 123140976 123140978 123140979 123140980 123140983 123140984 123170376 123186200
TUA : 125515763 125516239 125516497 125517417 125529189 125530472
LPER : 127308667 127308669 127309774 127322279
LRD : 124648635 124689326 124689611 124691419 124691667 124691669 124707651
MFLO : 136462581 136470963
SVS : 117837512 117844560 117862933
PVIR : 120704116 120704456 120704531 120704606
PHAI : 112877004 112877011
» show all
Taxonomy
Reference
Authors
Pichersky E, Lewinsohn E, Croteau R.
Title
Purification and characterization of S-linalool synthase, an enzyme involved in the production of floral scent in Clarkia breweri.
Journal
Reference
Authors
Lucker J, Bouwmeester HJ, Schwab W, Blaas J, van der Plas LH, Verhoeven HA.
Title
Expression of Clarkia S-linalool synthase in transgenic petunia plants results in the accumulation of S-linalyl-beta-D-glucopyranoside.
Journal
Reference
Authors
Dudareva N, Cseke L, Blanc VM, Pichersky E
Title
Evolution of floral scent in Clarkia: novel patterns of S-linalool synthase gene expression in the C. breweri flower.
Journal
Sequence
Other DBs
ExplorEnz - The Enzyme Database: 4.2.3.25
ExPASy - ENZYME nomenclature database: 4.2.3.25
LinkDB
All DBs