KEGG   ORTHOLOGY: K15359
Entry
K15359                      KO                                     
Symbol
hspA
Name
6-hydroxy-3-succinoylpyridine 3-monooxygenase [EC:1.14.13.163]
Pathway
map00760  Nicotinate and nicotinamide metabolism
map01100  Metabolic pathways
map01120  Microbial metabolism in diverse environments
Module
M00811  Nicotine degradation, pyrrolidine pathway, nicotine => succinate semialdehyde
Reaction
R09472  4-(6-hydroxypyridin-3-yl)-4-oxobutanoate,NADH:oxygen oxidoreductase (3-hydroxylating, succinate semialdehyde releasing)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00760 Nicotinate and nicotinamide metabolism
    K15359  hspA; 6-hydroxy-3-succinoylpyridine 3-monooxygenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.13.163  6-hydroxy-3-succinoylpyridine 3-monooxygenase
     K15359  hspA; 6-hydroxy-3-succinoylpyridine 3-monooxygenase
Other DBs
GO: 0034910
Genes
PPT: PPS_0380
PPUH: B479_02405
PPUD: DW66_0394
PMON: X969_00225
PMOT: X970_00225
PASI: LG197_07060(nicB)
RUG: QC826_02400
NRH: T8J41_20275
SSUM: Q9314_28325
Reference
PMID:18203859
  Authors
Tang H, Wang S, Ma L, Meng X, Deng Z, Zhang D, Ma C, Xu P
  Title
A novel gene, encoding 6-hydroxy-3-succinoylpyridine hydroxylase, involved in nicotine degradation by Pseudomonas putida strain S16.
  Journal
Appl Environ Microbiol 74:1567-74 (2008)
DOI:10.1128/AEM.02529-07
  Sequence
[ppt:PPS_0380]
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