KEGG ORTHOLOGY: K15397

ORTHOLOGY: K15397

Entry

K15397                      KO

Symbol

KCS

Name

3-ketoacyl-CoA synthase [EC:2.3.1.199]

Pathway

map00062

Fatty acid elongation

map01100

Metabolic pathways

map01110

Biosynthesis of secondary metabolites

map04626

Plant-pathogen interaction

Module

M00415

Fatty acid elongation in endoplasmic reticulum

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09103 Lipid metabolism
   00062 Fatty acid elongation
    K15397  KCS; 3-ketoacyl-CoA synthase
09150 Organismal Systems
  09159 Environmental adaptation
   04626 Plant-pathogen interaction
    K15397  KCS; 3-ketoacyl-CoA synthase
Enzymes [BR:ko01000]
2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.199  very-long-chain 3-oxoacyl-CoA synthase
     K15397  KCS; 3-ketoacyl-CoA synthase

Other DBs

RN:	R09419 R10825

GO:

0009922

Genes

ATH:

AT1G01120(KCS1) AT1G04220(KCS2) AT1G07720(KCS3) AT1G19440(KCS4) AT1G25450(KCS5) AT1G68530(KCS6) AT1G71160(KCS7) AT2G15090(KCS8) AT2G16280(KCS9) AT2G26250(KCS10) AT2G26640(KCS11) AT2G28630(KCS12) AT2G46720(KCS13) AT3G10280(KCS14) AT3G52160(KCS15) AT4G34250(KCS16) AT4G34510(KCS17) AT4G34520(KCS18) AT5G04530(KCS19) AT5G43760(KCS20) AT5G49070(KCS21)

ALY:	9299143 9300030 9301477 9305213 9305214 9305233 9307172 9312197 9315242 9316328 9316838 9316881 9319946 9320229 9322281 9323417 9324733 9325447 9325562 9325724 9329114 9329484

CRB:	17875401 17877277 17878292 17878770 17880303 17883909 17886155 17887978 17888236 17889324 17890533 17890924 17891843 17892686 17895242 17896546 17897688 17898777 17899461 17899499 17900281

CPAP:

110808466 110809943 110811478 110812036 110812672 110813298 110813811 110814038 110814084 110814116 110819363 110819766 110823294 110823945 110823950 110824029

CIT:	102608675 102608959 102609752 102611858 102613293 102614172 102616191 102616815 102617332 102617526 102618016 102621546 102623609 102626149 102627644 102628384 102631264

CIC:

CICLE_v10000889mg CICLE_v10003348mg CICLE_v10003754mg CICLE_v10004736mg CICLE_v10004738mg CICLE_v10004792mg CICLE_v10006419mg CICLE_v10006481mg CICLE_v10007916mg CICLE_v10007953mg CICLE_v10008045mg CICLE_v10008053mg CICLE_v10011503mg CICLE_v10013522mg CICLE_v10019672mg CICLE_v10028243mg CICLE_v10028377mg CICLE_v10031329mg CICLE_v10031467mg

TCC:	18586234 18586263 18586264 18588179 18588689 18588970 18590770 18591390 18603097 18603098 18603100 18603101 18605440 18607775 18609267 18613906

PVU:

PHAVU_001G014100g PHAVU_003G031300g PHAVU_003G160400g PHAVU_004G076300g PHAVU_005G140100g PHAVU_006G184900g PHAVU_006G215000g PHAVU_007G009100g PHAVU_007G009200g PHAVU_007G027100g PHAVU_007G064000g PHAVU_007G110500g PHAVU_007G279500g PHAVU_009G023600g PHAVU_009G084500g PHAVU_009G199000g PHAVU_009G249200g PHAVU_009G257100g PHAVU_011G068900g

VRA:	106756415 106758797 106760038 106760153 106762302 106762352 106763681 106765300 106769152 106769687 106770661 106772353 106772416 106772491 106772800 106774992 106775630 106776380 106776817

VAR:	108321068 108322330 108322740 108324118 108324122 108324316 108324759 108324980 108326637 108331892 108332053 108332065 108333443 108335193 108338049 108339663 108341691 108342548 108344830

VUN:	114163245 114163972 114164069 114164645 114168995 114169318 114178266 114181562 114184116 114188635 114189075 114189901 114190894 114191811 114191865 114192220 114192473 114193995 114195840

CCAJ:

109791800 109792891 109794255 109796791 109797390 109797719 109798930 109800370 109800836 109803215 109803797 109804381 109806452 109812001 109812129 109813156 109816913 109819104

LJA:

Lj0g3v0065089.1(Lj0g3v0065089.1) Lj0g3v0078429.1(Lj0g3v0078429.1) Lj0g3v0216389.1(Lj0g3v0216389.1) Lj0g3v0220359.1(Lj0g3v0220359.1) Lj0g3v0241719.1(Lj0g3v0241719.1) Lj0g3v0246159.1(Lj0g3v0246159.1) Lj0g3v0324009.1(Lj0g3v0324009.1) Lj1g3v1798580.1(Lj1g3v1798580.1) Lj1g3v1914960.1(Lj1g3v1914960.1) Lj1g3v2296500.1(Lj1g3v2296500.1) Lj1g3v4667830.1(Lj1g3v4667830.1) Lj1g3v5060470.1(Lj1g3v5060470.1) Lj2g3v0856560.1(Lj2g3v0856560.1) Lj2g3v1154110.1(Lj2g3v1154110.1) Lj3g3v0170770.1(Lj3g3v0170770.1) Lj3g3v3363310.1(Lj3g3v3363310.1) Lj4g3v1812470.1(Lj4g3v1812470.1) Lj4g3v1812470.2(Lj4g3v1812470.2) Lj5g3v0106070.1(Lj5g3v0106070.1) Lj5g3v2203980.1(Lj5g3v2203980.1) Lj5g3v2288650.1(Lj5g3v2288650.1) Lj5g3v2288650.2(Lj5g3v2288650.2) Lj5g3v2288660.1(Lj5g3v2288660.1) Lj6g3v1464000.1(Lj6g3v1464000.1) Lj6g3v2019780.1(Lj6g3v2019780.1)

FVE:	101293199 101294912 101297691 101298249 101298755 101305919 101307175 101307579 101309137 101310169 101311234 101312882 101312957 101313029 101313171

RCN:	112168776 112169542 112169592 112170275 112171065 112171233 112171831 112171863 112174521 112174779 112180806 112182122 112184738 112186018 112186661 112189629 112198004 112198227 112201921

PPER:

109946455 18767026 18768236 18769222 18774919 18784606 18784627 18785426 18785809 18786164 18786238 18786995 18788924 18789438 18790858 18790923 18791652 18792826 18793078 18793503

PAVI:

110744938 110744940 110748590 110749450 110750300 110754428 110756495 110756677 110756678 110756705 110757133 110757630 110759898 110763586 110767736 110769110 110770227 110771877 110773665

MNT:	112092975 21384146 21384179 21385988 21387442 21388025 21388161 21393586 21394144 21396138 21397793 21401520 21401598 21406199 21408145 21408146 21408320

CSV:	101203776 101206967 101209161 101213216 101213684 101215063 101215310 101215547 101217359 101217470 101218433 101219531 101221340 101221849 101222954

CMO:	103483144 103483657 103484018 103484019 103484209 103487967 103489283 103490572 103493715 103497180 103497181 103500175 103500178 103502712 103502720

BHJ:	120069716 120070313 120071086 120072283 120076586 120076666 120081149 120081505 120082037 120082767 120085719 120087953 120089423 120090277

MCHA:

111007764 111008051 111009272 111010111 111010122 111011424 111011446 111014024 111014523 111015402 111016318 111019525 111023122 111023789

CMOS:

111431897 111432137 111441071 111442975 111444318 111445762 111446876 111447035 111448188 111449760 111449914 111451001 111452255 111452609 111454409 111454833 111458367 111461763 111464683

CPEP:

111776416 111776813 111780723 111782644 111787789 111788208 111788473 111790480 111790639 111793960 111794443 111796697 111798432 111800694 111801014 111801556 111802364 111807236 111811560

RCU:	8258614 8262680 8262681 8266006 8266007 8266305 8271426 8273206 8276218 8278744 8280191 8280192 8280193 8283500 8285180 8285787 8287224 8288936

JCU:	105628194 105632070 105632222 105632383 105633800 105634862 105638055 105639303 105642024 105642784 105648863

EGT:	105949174 105952348 105953274 105953277 105955394 105959167 105961105 105961299 105963951 105966073 105968106 105969896 105969899 105970067 105971935 105974299 105975204 105975300

BVG:	104886809 104886938 104887704 104890324 104896300 104896500 104897138 104897143 104897892 104898217 104900185 104902115 104904140 104904349 104905850 104905974 104905984 104906580

SOE:	110775328 110777183 110778449 110778765 110778766 110779007 110782427 110787326 110790219 110791705 110792923 110793626 110796501 110796508 110797754 110798999 110803216

MING:

122057160 122057564 122058613 122061078 122061441 122066600 122073316 122076945 122077023 122078064 122078386 122079382 122079897 122082672 122083466 122085915 122090144

TSS:	122645455 122645459 122646485 122646769 122649612 122649791 122650053 122650296 122651917 122652142 122659807 122661832 122663938 122664626 122664673 122667792 122668159 122672788

DOSA:

Os01t0529800-01(Os01g0529800) Os02t0205500-01(Os02g0205500) Os02t0731900-01(Os02g0731900) Os02t0813600-01(Os02g0813600) Os03t0162650-01(Os03g0162650) Os03t0162800-01(Os03g0162800) Os03t0181500-01(Os03g0181500) Os03t0220100-01(Os03g0220100) Os03t0245700-02(Os03g0245700) Os03t0382100-01(Os03g0382100) Os03t0383600-01(Os03g0383600) Os04t0116800-01(Os04g0116800) Os05t0568000-02(Os05g0568000) Os05t0574600-01(Os05g0574600) Os06t0260500-00(Os06g0260500) Os06t0262800-01(Os06g0262800) Os06t0598800-01(Os06g0598800) Os09t0360500-01(Os09g0360500) Os09t0521100-01(Os09g0521100) Os10t0416200-01(Os10g0416200) Os10t0472900-01(Os10g0472900) Os11t0591200-01(Os11g0591200)

TDC:

119268722 119271932 119272895 119276878 119282084 119284531 119284664 119284705 119284962 119285108 119287171 119287172 119288151 119289308 119289668 119291007 119291176 119291468 119291499 119291655 119292558 119293084 119294513 119295022 119295877 119297715 119300614 119301366 119302514 119305009 119308972 119310405 119310822 119311192 119311193 119314349 119314579 119316587 119317769 119317983 119318477 119318702 119319355 119320267 119321134 119322278 119322720 119324043 119324673 119325190 119325666 119327449 119327464 119329793 119330400 119330914 119330931 119331577 119332449 119332481 119332788 119335457 119337759 119339985 119340152 119340524 119341001 119341156 119341677 119341717 119341764 119341765 119341796 119349511 119349619 119350057 119350922 119352170 119353445 119354200 119354741 119357370 119360498 119368569

TAES:

100270666 123039525 123042381 123042491 123045237 123046355 123050332 123050334 123057153 123059128 123061981 123066328 123068800 123069222 123070683 123075373 123076631 123077258 123077607 123079091 123083432 123084705 123084837 123084879 123085149 123085176 123085574 123085848 123086141 123087387 123090530 123090533 123092777 123093211 123093245 123093399 123094175 123096944 123097465 123098077 123098215 123098476 123098513 123098672 123099312 123099314 123099318 123103560 123104459 123105435 123106652 123107462 123111767 123112754 123112756 123114541 123115158 123121063 123121334 123122232 123122234 123123742 123124100 123127265 123128295 123128937 123129184 123129986 123129989 123130001 123131105 123131917 123134718 123135914 123136897 123138148 123138663 123139638 123140104 123141931 123142684 123143431 123144345 123145404 123145550 123146095 123146347 123146880 123146994 123147433 123147598 123147685 123148135 123150063 123150253 123150690 123150819 123152534 123152742 123153034 123154417 123157783 123159335 123161291 123161816 123162238 123162572 123162598 123162695 123162913 123163563 123163769 123164205 123164286 123164764 123164836 123165419 123166772 123167050 123167711 123167808 123167910 123169500 123169747 123170272 123170808 123171011 123171579 123172594 123174842 123175596 123176322 123176447 123176662 123180032 123181016 123183181 123183220 123183346 123184201 123186328

DCT:	110095190 110095943 110097297 110097994 110100817 110100882 110102028 110102409 110103027 110104210 110105070 110106652 110111736 110113540 110113718 110116628

PEQ:	110018831 110019290 110019965 110024784 110026642 110027196 110027349 110027560 110027699 110028540 110028548 110029416 110029795 110029977 110033128 110038920

AOF:	109819936 109820023 109820853 109826929 109827042 109828619 109834530 109835227 109835640 109836257 109836259 109844724 109845458 109851314

NCOL:

116246380 116247384 116252963 116254266 116254276 116255602 116255654 116255732 116257473 116258988 116260119 116262893 116263048 116263360 116267054 116267816

ATR:	18423985 18425089 18429546 18431078 18432005 18432207 18433754 18436493 18437316 18438452 18440365 18440808 18444705 18447840

SMO:	SELMODRAFT_100466 SELMODRAFT_101692 SELMODRAFT_231244 SELMODRAFT_43379 SELMODRAFT_437285 SELMODRAFT_443640 SELMODRAFT_444233 SELMODRAFT_445704 SELMODRAFT_445717 SELMODRAFT_53281 SELMODRAFT_75021 SELMODRAFT_79947 SELMODRAFT_91671 SELMODRAFT_94459

PPP:	112276381 112277750 112278676 112283525 112285705 112286144 112286436 112287776 112288060 112289406 112291646

CRE:	CHLRE_07g319600v5 CHLRE_07g320550v5 CHLRE_17g722150v5

VCN:	VOLCADRAFT_109539 VOLCADRAFT_61822 VOLCADRAFT_91861 VOLCADRAFT_95052

MNG:	MNEG_0210 MNEG_0978 MNEG_10025 MNEG_10138 MNEG_10761 MNEG_11333 MNEG_11436 MNEG_12583 MNEG_1319 MNEG_14110 MNEG_14135 MNEG_14506 MNEG_3134 MNEG_3349 MNEG_6070 MNEG_6733

CSL:	COCSUDRAFT_12119 COCSUDRAFT_12451 COCSUDRAFT_18441 COCSUDRAFT_18466 COCSUDRAFT_26029 COCSUDRAFT_36731 COCSUDRAFT_44199 COCSUDRAFT_48294 COCSUDRAFT_57989 COCSUDRAFT_58877 COCSUDRAFT_64433

CVR:	CHLNCDRAFT_141048 CHLNCDRAFT_48950

APRO:

F751_2378 F751_5872

CME:	CYME_CMD118C

GSL:	Gasu_26960

CCP:	CHC_T00009104001

DDI:	DDB_G0283621(cutA)

DPP:	DICPUDRAFT_53740

DFA:	DFA_08982(cutA)

EHI:	EHI_009370(47.t00001) EHI_092190(50.t00014) EHI_158240(242.t00002)

EDI:	EDI_102180 EDI_154050 EDI_193210 EDI_216630

EIV:	EIN_065710 EIN_114200 EIN_371670

FCY:	FRACYDRAFT_273692

AAF:	AURANDRAFT_38612

EHX:	EMIHUDRAFT_418258(CHS2) EMIHUDRAFT_439552 EMIHUDRAFT_631877(CHS1)

GLA:	GL50803_0092729

» show all

Reference

PMID:10559443

Authors

Yephremov A, Wisman E, Huijser P, Huijser C, Wellesen K, Saedler H

Title

Characterization of the FIDDLEHEAD gene of Arabidopsis reveals a link between adhesion response and cell differentiation in the epidermis.

Journal

Plant Cell 11:2187-201 (1999)
DOI:10.1105/tpc.11.11.2187

Sequence

[ath:AT2G26250]

Reference

PMID:10074711

Authors

Todd J, Post-Beittenmiller D, Jaworski JG

Title

KCS1 encodes a fatty acid elongase 3-ketoacyl-CoA synthase affecting wax biosynthesis in Arabidopsis thaliana.

Journal

Plant J 17:119-30 (1999)
DOI:10.1046/j.1365-313x.1999.00352.x

Sequence

[ath:AT1G01120]

Reference

PMID:10330468

Authors

Millar AA, Clemens S, Zachgo S, Giblin EM, Taylor DC, Kunst L

Title

CUT1, an Arabidopsis gene required for cuticular wax biosynthesis and pollen fertility, encodes a very-long-chain fatty acid condensing enzyme.

Journal

Plant Cell 11:825-38 (1999)
DOI:10.1105/tpc.11.5.825

Sequence

[ath:AT1G68530]

Reference

PMID:11130071

Authors

Gray JE, Holroyd GH, van der Lee FM, Bahrami AR, Sijmons PC, Woodward FI, Schuch W, Hetherington AM

Title

The HIC signalling pathway links CO2 perception to stomatal development.

Journal

Nature 408:713-6 (2000)
DOI:10.1038/35047071

Sequence

[ath:AT2G46720]

Reference

PMID:16765910

Authors

Blacklock BJ, Jaworski JG

Title

Substrate specificity of Arabidopsis 3-ketoacyl-CoA synthases.

Journal

Biochem Biophys Res Commun 346:583-90 (2006)
DOI:10.1016/j.bbrc.2006.05.162

LinkDB

ORTHOLOGY: K10247

Entry

K10247                      KO

Symbol

ELOVL1

Name

elongation of very long chain fatty acids protein 1 [EC:2.3.1.199]

Pathway

map00062

Fatty acid elongation

map01040

Biosynthesis of unsaturated fatty acids

map01100

Metabolic pathways

map01110

Biosynthesis of secondary metabolites

map01212

Fatty acid metabolism

Module

M00415

Fatty acid elongation in endoplasmic reticulum

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09103 Lipid metabolism
   00062 Fatty acid elongation
    K10247  ELOVL1; elongation of very long chain fatty acids protein 1
   01040 Biosynthesis of unsaturated fatty acids
    K10247  ELOVL1; elongation of very long chain fatty acids protein 1
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01004 Lipid biosynthesis proteins
    K10247  ELOVL1; elongation of very long chain fatty acids protein 1
Enzymes [BR:ko01000]
2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.199  very-long-chain 3-oxoacyl-CoA synthase
     K10247  ELOVL1; elongation of very long chain fatty acids protein 1
Lipid biosynthesis proteins [BR:ko01004]
Elongase
  PUFA
   K10247  ELOVL1; elongation of very long chain fatty acids protein 1

Other DBs

RN:	R09419 R10825

GO:

0009922

Genes

HSA:	64834(ELOVL1)

PTR:	456820(ELOVL1)

PPS:	100986082(ELOVL1)

GGO:	101152434(ELOVL1)

PON:	100173790(ELOVL1)

NLE:	100593990(ELOVL1)

MCC:	700557(ELOVL1)

MCF:	101866566(ELOVL1)

MTHB:

126960653

CSAB:

103224964(ELOVL1)

CATY:

105594639(ELOVL1)

PANU:

101001930(ELOVL1)

TGE:	112606773(ELOVL1)

RRO:	104669029(ELOVL1)

RBB:	108535699(ELOVL1)

TFN:	117092736(ELOVL1)

PTEH:

111548725(ELOVL1)

CANG:

105514215(ELOVL1)

CJC:	100409750(ELOVL1)

SBQ:	101044551(ELOVL1)

CSYR:

103260443(ELOVL1)

MMUR:

105877420(ELOVL1)

LCAT:

123634248(ELOVL1)

PCOQ:

105814101(ELOVL1)

OGA:	100949949(ELOVL1)

MMU:	54325(Elovl1)

MCAL:

110293741(Elovl1)

MPAH:

110322772(Elovl1)

RNO:	679532(Elovl1)

MCOC:

116096524(Elovl1)

MUN:	110552923(Elovl1)

CGE:	100767465(Elovl1)

MAUA:

101827189(Elovl1)

PLEU:

114709353(Elovl1)

MORG:

121448552(Elovl1)

MFOT:

126513158

AAMP:

119816419(Elovl1)

NGI:	103743853(Elovl1)

HGL:	101705922(Elovl1)

CPOC:

100718818(Elovl1)

CCAN:

109694041(Elovl1)

DORD:

105986201(Elovl1)

DSP:	122106217(Elovl1)

NCAR:

124983953

OCU:

100350176

OPI:	101530468(ELOVL1)

TUP:	102482262(ELOVL1)

GVR:	103598280(ELOVL1)

CFA:	100855761(ELOVL1)

CLUD:

112642644(ELOVL1)

VVP:	112914830(ELOVL1)

VLG:	121481654(ELOVL1)

AML:	100476157(ELOVL1)

UMR:	103670810(ELOVL1)

UAH:	113254789(ELOVL1)

UAR:	123793803(ELOVL1)

ELK:

111143031

LLV:

125097972

MPUF:

101672748(ELOVL1)

ORO:	101372184(ELOVL1)

EJU:	114224186(ELOVL1)

ZCA:	113933660(ELOVL1)

MLX:	118019525(ELOVL1)

NSU:	110574971(ELOVL1)

LWW:	102737999(ELOVL1)

FCA:	101097500(ELOVL1)

PYU:	121026990(ELOVL1)

PBG:	122480383(ELOVL1)

LRUF:

124514670

PTG:	102970388(ELOVL1)

PPAD:

109254788(ELOVL1)

AJU:	106970211(ELOVL1)

HHV:	120236059(ELOVL1)

BTA:	540348(ELOVL1)

BOM:	102285922(ELOVL1)

BIU:	109556406(ELOVL1)

BBUB:

102410220(ELOVL1)

BBIS:

105004860(ELOVL1)

CHX:	102170380(ELOVL1)

OAS:	101110801(ELOVL1)

ODA:	120856284(ELOVL1)

CCAD:

122437100(ELOVL1)

SSC:	100312969(ELOVL1)

CFR:	102519775(ELOVL1)

CBAI:

105072714(ELOVL1)

CDK:	105090906(ELOVL1)

VPC:	102539548(ELOVL1)

BACU:

103007581(ELOVL1)

LVE:	103080456(ELOVL1)

OOR:	101269204(ELOVL1)

DLE:	111175701(ELOVL1)

PCAD:

102993438(ELOVL1)

PSIU:

116762821(ELOVL1)

ECB:	100053305(ELOVL1)

EPZ:	103557413(ELOVL1)

EAI:	106847905(ELOVL1)

MYB:	102246226(ELOVL1)

MYD:	102770278(ELOVL1)

MMYO:

118676450(ELOVL1)

MLF:	102420636(ELOVL1)

MNA:	107542721(ELOVL1)

PKL:	118724084(ELOVL1)

HAI:	109383409(ELOVL1)

DRO:	112314592(ELOVL1)

SHON:

119003331(ELOVL1)

AJM:	119052387(ELOVL1)

PDIC:

114497199(ELOVL1)

PHAS:

123831880(ELOVL1)

MMF:	118626606(ELOVL1)

RFQ:	117027008(ELOVL1)

PALE:

102880850(ELOVL1)

PGIG:

120619250(ELOVL1)

PVP:	105297087(ELOVL1)

RAY:	107499506(ELOVL1)

MJV:	108407025(ELOVL1)

TOD:	119235155(ELOVL1)

SARA:

101540754(ELOVL1)

LAV:	100667896(ELOVL1)

TMU:

101342815

ETF:	101643676(ELOVL1)

DNM:	101430163(ELOVL1)

MDO:	100014679(ELOVL1)

GAS:	123244300(ELOVL1)

SHR:	100920560(ELOVL1)

PCW:	110200196(ELOVL1)

OAA:	100081938(ELOVL1)

GGA:	424564(ELOVL1)

PCOC:

116233752(ELOVL1)

MGP:	100539668(ELOVL1)

CJO:	107317407(ELOVL1)

NMEL:

110402577(ELOVL1)

APLA:

101794230

ACYG:

106034065(ELOVL1)

AFUL:

116492093(ELOVL1)

TGU:	100225083(ELOVL1)

LSR:	110469261(ELOVL1)

SCAN:

103814954(ELOVL1)

PMOA:

120503307(ELOVL1)

OTC:	121345093(ELOVL1)

PRUF:

121362119(ELOVL1)

GFR:	102033945(ELOVL1)

FAB:	101811200(ELOVL1)

PHI:	102103239(ELOVL1)

PMAJ:

107208217(ELOVL1)

CCAE:

111933151(ELOVL1)

CCW:	104695272(ELOVL1)

CBRC:

103621936(ELOVL1)

ETL:	114066170(ELOVL1)

ZAB:	102074996(ELOVL1)

ACHL:

103807765(ELOVL1)

FPG:	101918168(ELOVL1)

FCH:	102054212(ELOVL1)

CLV:	102091789(ELOVL1)

EGZ:	104125516(ELOVL1)

NNI:	104015438(ELOVL1)

PLET:

104622172(ELOVL1)

PCRI:

104037392(ELOVL1)

PCAO:

104044175(ELOVL1)

ACUN:

113482593(ELOVL1)

TALA:

104361477(ELOVL1)

PADL:

103925171(ELOVL1)

AFOR:

103905568(ELOVL1)

ACHC:

115349101(ELOVL1)

HALD:

104320311(ELOVL1)

HLE:	104841085(ELOVL1)

AGEN:

126041508

GCL:

127018912

CCRI:

104156108(ELOVL1)

CSTI:

104560173(ELOVL1)

EHS:	104513659(ELOVL1)

CMAC:

104474942(ELOVL1)

MUI:	104538951(ELOVL1)

FGA:	104071593(ELOVL1)

GSTE:

104262853(ELOVL1)

LDI:	104347510(ELOVL1)

MNB:	103773403(ELOVL1)

OHA:	104338814(ELOVL1)

NNT:	104407633(ELOVL1)

DPUB:

104301548(ELOVL1)

PGUU:

104465870(ELOVL1)

ACAR:

104526250(ELOVL1)

CPEA:

104396711(ELOVL1)

AVIT:

104270077(ELOVL1)

CVF:	104286125(ELOVL1)

CUCA:

104057538(ELOVL1)

TEO:	104379690(ELOVL1)

BRHI:

104501862(ELOVL1)

AAM:	106499470(ELOVL1)

AROW:

112975969(ELOVL1)

NPD:	112942334(ELOVL1)

TGT:	104568768(ELOVL1)

DNE:	112981259(ELOVL1)

SCAM:

104141445(ELOVL1)

ASN:	102388057(ELOVL1)

AMJ:	102571703(ELOVL1)

CPOO:

109307384(ELOVL1)

PSS:	102444349(ELOVL1)

CMY:	102936820(ELOVL1)

CPIC:

101939683(ELOVL1)

TST:	117881564(ELOVL1)

CABI:

116833118(ELOVL1)

MRV:	120370894(ELOVL1)

ACS:	100556512(elovl1)

PVT:	110073724(ELOVL1)

SUND:

121928445(ELOVL1)

PBI:	103057461(ELOVL1)

PMUR:

107283452(ELOVL1)

CTIG:

120299028(ELOVL1)

TSR:	106538823(ELOVL1)

PGUT:

117664084(ELOVL1)

VKO:	123029689(ELOVL1)

PMUA:

114599139(ELOVL1)

ZVI:	118088611(ELOVL1)

GJA:	107106450(ELOVL1)

STOW:

125433068(ELOVL1)

XLA:	379510(elovl1.L) 380063(elovl1.S)

XTR:	549398(elovl1)

NPR:	108791172(ELOVL1)

RTEM:

120946117(ELOVL1)

BBUF:

120979214(ELOVL1)

BGAR:

122943703(ELOVL1)

DRE:	406725(elovl1b) 449816(elovl1a)

SRX:	107710545 107723066 107732201 107753833

SANH:

107656106 107665848 107677562 107700551

SGH:	107553254 107562086 107602768

CCAR:

109056897 109081052 109098431 109098432

CAUA:

113045626 113055170 113081973 113110786 113115333

PPRM:

120466880(elovl1b) 120482707(elovl1a)

MAMB:

125251666(elovl1a) 125276045(elovl1b)

IPU:	108270818(elovl1b) 108280856(elovl1a)

PHYP:

113525850 113546461

SMEO:

124390904(elovl1b) 124403233(elovl1a)

TFD:	113651676(elovl1a) 113657822(elovl1b)

AMEX:

103026677 103047025

EEE:	113575426 113590483

TRU:	101078198 101078639

TNG:	GSTEN00012629G001 GSTEN00028404G001

LCO:	104918444 109139250 109139251

NCC:	104957884 104965508

CGOB:

115006857 115021994

ELY:	117253403(elovl1b) 117263239(elovl1a)

EFO:	125896127(elovl1b) 125902401(elovl1a)

PLEP:

121938437(elovl1b) 121951907(elovl1a)

SLUC:

116046101(elovl1a) 116063228(elovl1b)

ECRA:

117950387(elovl1b) 117953848(elovl1a)

ESP:	116695850 116698639

PFLV:

114561831 114564751

GAT:	120815750(elovl1a) 120824449(elovl1b)

PPUG:

119209224(elovl1a) 119216483(elovl1b)

MSAM:

119900822(elovl1b) 119902107(elovl1a)

CUD:	121512298(elovl1b) 121519739(elovl1a)

ALAT:

119011926(elovl1a) 119028275(elovl1b)

MZE:	101477957 101481208

ONL:	100705565 100706973

OAU:	116316993(elovl1a) 116333322(elovl1b)

OLA:	101157810 101175390

OML:	112147866(elovl1a) 112150713(elovl1b)

XMA:	102219711 102235712

XCO:	114145795 114150757

XHE:	116721547 116725391

PRET:

PFOR:

PLAI:

PMEI:

GAF:	122838238(elovl1b) 122841454(elovl1a)

CVG:	107081984 107083337

CTUL:

119772953(elovl1b) 119786180(elovl1a)

GMU:	124869510(elovl1a) 124873437(elovl1b)

NFU:	107383975 107393239

KMR:	108230856(elovl1b) 108239575(elovl1a)

ALIM:

106513888 106534581

NWH:	119407915(elovl1b) 119415098(elovl1a)

AOCE:

111578796 111581924

MCEP:

125009299(elovl1b) 125011303(elovl1a)

CSEM:

103396063 103397290

POV:	109625835 109640212

SSEN:

122778365(elovl1a) 122781283(elovl1b)

HHIP:

117759964(elovl1b) 117778684(elovl1a)

HSP:	118118252(elovl1a) 124854803(elovl1b)

LCF:	108877409(elovl1b) 108883473(elovl1a)

SDU:	111232160 111238981

SLAL:

111654473 111656380

XGL:	120790657(elovl1b) 120799245(elovl1a)

HCQ:	109529550 109532265

BPEC:

110157633 110167788

MALB:

109957765 109964021

BSPL:

114844740(elovl1a) 114853389(elovl1b)

SASA:

100195361(elov7) 100286454(elov1) 106569200 106599266

STRU:

115151578 115157093 115158017 115169681

OTW:	112226870 112246671(elovl1b) 112250658 112260539

OMY:	110508661 110524065 110530395(elovl1a) 110537626(elovl1b)

OGO:	123997396 123997488(elovl1b) 124009949 124040918

ONE:	115103022 115108103 115109064 115114483

SALP:

111952630 111956972 111976123 111979783

SNH:	120019825 120053657(elovl1b) 120054405 120055282

CCLU:

121533732 121534639 121576431 121581518

ELS:	105019159 105028136

SFM:

108923705

PKI:	111846009(elovl1)

AANG:

118224567(elovl1b) 118229260(elovl1a)

LOC:	102699034(elovl1)

PSPA:

121327249 121330968

ARUT:

117405636 117416930

LCM:	102345269(ELOVL1)

CMK:

103174616

RTP:	109927895(elovl1)

DSR:

110188482

DWI:

26529291

DMO:	Dmoj_GI19161

DAZ:

DNV:

DHE:

RZE:

MDE:

LCQ:

AGA:	AgaP_AGAP005513

ACOZ:

120953515

AAG:	5575619 5578329

AALB:

109429007

CQU:	CpipJ_CPIJ000105

CPII:

AME:

BTER:

CCAL:

OBB:	114874851 114874994 114879406 114881631 114881881

MGEN:

117223955 117223997

SOC:	105193147 105195651

ACEP:

VEM:

HST:

DQU:

CFO:

LHU:

PGC:	109854968 109854969

OBO:	105274943 105282672

PCF:	106792421 106792917 106794032 106794040

NVI:	100118619 100123468

CSOL:

TPRE:

FAS:

DAM:

CINS:

LHT:

CCIN:

DPA:

NVL:

PPYR:

BTAB:

CLEC:

HHAL:

106678558 106678566 106678568 106680802

FOC:

113209646

ZNE:	110829077 110840435

EAF:

111710340

ISC:	IscW_ISCW002735 IscW_ISCW015237

RMP:

119170341

VDE:

111248785

VJA:	111259707 111265876

TUT:	107359721 107360691 107363070 107369340 107371135 107371905 112538830

DPTE:

113792444

DFR:	124496323 124500558

PTEP:

107452017

SDM:	118190896 118195727

HRF:	124142313 124142316

HRJ:	124291734 124291798

OVI:	T265_08976

ATEN:

116305055

» show all

Reference

PMID:10791983

Authors

Tvrdik P, Westerberg R, Silve S, Asadi A, Jakobsson A, Cannon B, Loison G, Jacobsson A

Title

Role of a new mammalian gene family in the biosynthesis of very long chain fatty acids and sphingolipids.

Journal

J Cell Biol 149:707-18 (2000)
DOI:10.1083/jcb.149.3.707

Sequence

[mmu:54325]

Reference

PMID:20937905

Authors

Ohno Y, Suto S, Yamanaka M, Mizutani Y, Mitsutake S, Igarashi Y, Sassa T, Kihara A

Title

ELOVL1 production of C24 acyl-CoAs is linked to C24 sphingolipid synthesis.

Journal

Proc Natl Acad Sci U S A 107:18439-44 (2010)
DOI:10.1073/pnas.1005572107

LinkDB

ORTHOLOGY: K10205

Entry

K10205                      KO

Symbol

ELOVL2

Name

elongation of very long chain fatty acids protein 2 [EC:2.3.1.199]

Pathway

map00062

Fatty acid elongation

map01040

Biosynthesis of unsaturated fatty acids

map01100

Metabolic pathways

map01110

Biosynthesis of secondary metabolites

map01212

Fatty acid metabolism

Module

M00415

Fatty acid elongation in endoplasmic reticulum

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09103 Lipid metabolism
   00062 Fatty acid elongation
    K10205  ELOVL2; elongation of very long chain fatty acids protein 2
   01040 Biosynthesis of unsaturated fatty acids
    K10205  ELOVL2; elongation of very long chain fatty acids protein 2
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01004 Lipid biosynthesis proteins
    K10205  ELOVL2; elongation of very long chain fatty acids protein 2
Enzymes [BR:ko01000]
2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.199  very-long-chain 3-oxoacyl-CoA synthase
     K10205  ELOVL2; elongation of very long chain fatty acids protein 2
Lipid biosynthesis proteins [BR:ko01004]
Elongase
  PUFA
   K10205  ELOVL2; elongation of very long chain fatty acids protein 2

Other DBs

RN:	R09419 R10825

GO:

0009922

Genes

HSA:	54898(ELOVL2)

PTR:	750765(ELOVL2)

PPS:	100979903(ELOVL2)

GGO:	101140898(ELOVL2)

PON:	100454419(ELOVL2)

NLE:	100600368(ELOVL2)

MCC:	703030(ELOVL2)

MCF:	102124038(ELOVL2)

MTHB:

126953875

CSAB:

103222171(ELOVL2)

CATY:

105572532(ELOVL2)

PANU:

101024536(ELOVL2)

TGE:	112622847(ELOVL2)

RRO:	104657375(ELOVL2)

RBB:	108541609(ELOVL2)

TFN:	117086722(ELOVL2)

PTEH:

111521796(ELOVL2)

CANG:

105526809(ELOVL2)

CJC:	100386025(ELOVL2)

SBQ:	101041837(ELOVL2)

CSYR:

103270045(ELOVL2)

MMUR:

105865215(ELOVL2)

LCAT:

123638774(ELOVL2)

PCOQ:

105823063(ELOVL2)

OGA:	100959216(ELOVL2)

MMU:	54326(Elovl2)

MCAL:

110307913(Elovl2)

MPAH:

110333993(Elovl2)

RNO:	498728(Elovl2)

MCOC:

116082068(Elovl2)

MUN:	110554600(Elovl2)

CGE:	100764278(Elovl2)

MAUA:

101838453(Elovl2)

PLEU:

114692106(Elovl2)

MORG:

121434019(Elovl2)

MFOT:

126501541

AAMP:

119817907(Elovl2)

NGI:	103732892(Elovl2)

HGL:	101699326(Elovl2)

CPOC:

100724371(Elovl2)

CCAN:

109678157(Elovl2)

DORD:

105985948(Elovl2)

DSP:	122107010(Elovl2)

NCAR:

124989013

OCU:

100358530

OPI:	101518847(ELOVL2)

TUP:	102468519(ELOVL2)

GVR:	103597257(ELOVL2)

CFA:	488219(ELOVL2)

CLUD:

112658378(ELOVL2)

VVP:	112920434(ELOVL2)

VLG:	121500799(ELOVL2)

AML:	100472915(ELOVL2)

UMR:	103664917(ELOVL2)

UAH:	113264241(ELOVL2)

UAR:	123801592(ELOVL2)

ELK:

111156730

LLV:

125103144

MPUF:

101684694(ELOVL2)

ORO:	101379042(ELOVL2)

EJU:	114212559(ELOVL2)

ZCA:	113927700(ELOVL2)

MLX:	118027455(ELOVL2)

NSU:	110586935(ELOVL2)

LWW:	102750542(ELOVL2)

FCA:	101093184(ELOVL2)

PYU:	121020305(ELOVL2)

PBG:	122489242(ELOVL2)

LRUF:

124528008

PTG:	102972782(ELOVL2)

PPAD:

109249646(ELOVL2)

AJU:	106972032(ELOVL2)

HHV:	120231668(ELOVL2)

BTA:	615756(ELOVL2)

BOM:	102274409(ELOVL2)

BIU:	109576753(ELOVL2)

BBUB:

102403874(ELOVL2)

BBIS:

104985620(ELOVL2)

CHX:	102177113(ELOVL2)

OAS:	101116613(ELOVL2)

ODA:	120869909(ELOVL2)

CCAD:

122429919(ELOVL2)

SSC:	100153368(ELOVL2)

CFR:	102519943(ELOVL2)

CBAI:

105061619(ELOVL2)

CDK:	105102078(ELOVL2)

VPC:	102529612(ELOVL2)

BACU:

103008327(ELOVL2)

LVE:	103085369(ELOVL2)

OOR:	101280861(ELOVL2)

DLE:	111181363(ELOVL2)

PCAD:

102991233(ELOVL2)

PSIU:

116761514(ELOVL2)

ECB:	100063624(ELOVL2)

EPZ:	103567404(ELOVL2)

EAI:	106833224(ELOVL2)

MYB:	102245763(ELOVL2) 102255907

MYD:	102763123(ELOVL2)

MMYO:

118677101(ELOVL2)

MLF:	102423696(ELOVL2)

MNA:	107530396(ELOVL2)

PKL:	118723603(ELOVL2)

HAI:	109377448(ELOVL2)

DRO:	112309242(ELOVL2)

SHON:

118981153(ELOVL2)

AJM:	119054858(ELOVL2)

PDIC:

114497924(ELOVL2)

PHAS:

123824070(ELOVL2)

MMF:	118626259(ELOVL2)

RFQ:	117027580(ELOVL2)

PALE:

102891448(ELOVL2)

PGIG:

120598646(ELOVL2)

PVP:	105300850(ELOVL2)

RAY:	107497211(ELOVL2)

MJV:	108394296(ELOVL2)

TOD:	119251608(ELOVL2)

SARA:

101539805(ELOVL2)

LAV:	100677669(ELOVL2)

TMU:

101353627

ETF:	101640613(ELOVL2)

DNM:	101421389(ELOVL2)

MDO:	100026914(ELOVL2)

GAS:	123240308(ELOVL2)

SHR:	100922613(ELOVL2)

PCW:	110192019(ELOVL2)

OAA:	100084190(ELOVL2)

GGA:	420858(ELOVL2)

PCOC:

116226514(ELOVL2)

MGP:	100538879(ELOVL2)

CJO:	107309660(ELOVL2)

NMEL:

110394508(ELOVL2)

APLA:

101796744(ELOVL2)

ACYG:

106041854(ELOVL2)

AFUL:

116485466(ELOVL2)

TGU:	100190615(ELOVL2)

LSR:	110473728(ELOVL2)

SCAN:

103814974(ELOVL2)

PMOA:

120503581(ELOVL2)

OTC:	121340442(ELOVL2)

PRUF:

121357794(ELOVL2)

GFR:	102039991(ELOVL2)

FAB:	101813473(ELOVL2)

PHI:	102106501(ELOVL2)

PMAJ:

107214099(ELOVL2)

CCAE:

111923801(ELOVL2)

CCW:	104691457(ELOVL2)

CBRC:

103613138(ELOVL2)

ETL:	114066346(ELOVL2)

ZAB:	102072400(ELOVL2)

ACHL:

103799833(ELOVL2)

FPG:	101916881(ELOVL2)

FCH:	102048237(ELOVL2)

CLV:	102096454(ELOVL2)

EGZ:	104124799(ELOVL2)

NNI:	104021823(ELOVL2)

PLET:

104614582(ELOVL2)

PCRI:

104038335(ELOVL2)

PCAO:

104052414(ELOVL2)

ACUN:

113477006(ELOVL2)

TALA:

104366846(ELOVL2)

PADL:

103919028(ELOVL2)

AFOR:

103894334(ELOVL2)

ACHC:

115352905(ELOVL2)

HALD:

104323985

HLE:	104835307(ELOVL2)

AGEN:

126048707

GCL:

127012662

CCRI:

104161574(ELOVL2)

EHS:	104504637(ELOVL2)

CMAC:

104484464(ELOVL2)

MUI:	104542249(ELOVL2)

FGA:	104078112(ELOVL2)

GSTE:

104262343

LDI:	104354901(ELOVL2)

MNB:	103778727(ELOVL2)

OHA:	104326707(ELOVL2)

NNT:	104408005(ELOVL2)

DPUB:

104302284(ELOVL2)

PGUU:

104467565

ACAR:

104532636

CPEA:

104391606(ELOVL2)

AVIT:

104277638(ELOVL2)

CVF:	104285703(ELOVL2)

CUCA:

104062153(ELOVL2)

TEO:	104383589(ELOVL2)

BRHI:

104500415(ELOVL2)

AAM:	106483674(ELOVL2)

AROW:

112965355(ELOVL2)

NPD:	112947295(ELOVL2)

TGT:	104567573(ELOVL2)

DNE:

112992040

SCAM:

104146087(ELOVL2)

ASN:	102378375(ELOVL2)

AMJ:	102566964(ELOVL2)

CPOO:

109315505(ELOVL2)

GGN:	109301401(ELOVL2)

PSS:	102457606(ELOVL2)

CMY:	102930723(ELOVL2)

CPIC:

101939130(ELOVL2)

TST:	117873199(ELOVL2)

CABI:

116828590(ELOVL2)

MRV:	120398889(ELOVL2)

ACS:	100558809(elovl2)

PVT:	110080848(ELOVL2)

SUND:

121928533(ELOVL2)

PBI:	103059597(ELOVL2)

PMUR:

107282982(ELOVL2)

CTIG:

120310780(ELOVL2)

PGUT:

117672482(ELOVL2)

VKO:	123036511(ELOVL2)

PMUA:

114600905(ELOVL2)

ZVI:	118090446(ELOVL2)

GJA:	107111768(ELOVL2)

STOW:

125439410(ELOVL2)

XLA:	108704446(elovl2.S) 447388(elovl2.L)

XTR:	548913(elovl2)

NPR:	108788457(ELOVL2)

RTEM:

120940714(ELOVL2)

BBUF:

121001860(ELOVL2)

BGAR:

122938664(ELOVL2)

DRE:	678614(elovl2)

SRX:	107731498(elovl2)

SGH:	107565488(elovl2)

CCAR:

109048624 109049010

CAUA:

113041848 113100627

PPRM:

120475815(elovl2)

MAMB:

125258391(elovl2)

IPU:	108256217(elovl2)

PHYP:

113532568(elovl2)

SMEO:

124375535(elovl2)

TFD:	113659760(elovl2)

AMEX:

103027447(elovl2)

EEE:	113579578(elovl2)

SASA:

100192341(elovl2)

STRU:

115149990

OTW:	112215311(elovl2)

OMY:	101268971 110490828

OGO:	123991390(elovl2)

ONE:

115104868

SALP:

111972818(elovl2)

SNH:	120028158(elovl2)

CCLU:

121549678 121568674

ELS:	105019517(elovl2)

SFM:	108927542(elovl2)

PKI:	111840844(elovl2)

AANG:

118226280(elovl2)

LOC:	102693156(elovl2)

PSPA:

121313048 121314530

ARUT:

117400378(elovl2) 117435692

PSEX:

120529831(elovl2)

LCM:	102346933(ELOVL2)

CMK:	103184556(elovl2)

RTP:	109927373(elovl2)

BBEL:

RSAN:

VDE:

VJA:

LGI:	LOTGIDRAFT_199086

PCAN:

BGT:

HRF:

HRJ:

CRG:

PMAX:

MMER:

LAK:	106164401 106175626

AQU:

100635150

MBR:	MONBRDRAFT_38186

» show all

Reference

PMID:10791983

Authors

Tvrdik P, Westerberg R, Silve S, Asadi A, Jakobsson A, Cannon B, Loison G, Jacobsson A

Title

Role of a new mammalian gene family in the biosynthesis of very long chain fatty acids and sphingolipids.

Journal

J Cell Biol 149:707-18 (2000)
DOI:10.1083/jcb.149.3.707

Sequence

[mmu:54326]

Reference

PMID:12371743

Authors

Leonard AE, Kelder B, Bobik EG, Chuang LT, Lewis CJ, Kopchick JJ, Mukerji P, Huang YS

Title

Identification and expression of mammalian long-chain PUFA elongation enzymes.

Journal

Lipids 37:733-40 (2002)
DOI:10.1007/s11745-002-0955-6

LinkDB

ORTHOLOGY: K10248

Entry

K10248                      KO

Symbol

ELOVL3

Name

elongation of very long chain fatty acids protein 3 [EC:2.3.1.199]

Pathway

map00062

Fatty acid elongation

map01040

Biosynthesis of unsaturated fatty acids

map01100

Metabolic pathways

map01110

Biosynthesis of secondary metabolites

map01212

Fatty acid metabolism

Module

M00415

Fatty acid elongation in endoplasmic reticulum

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09103 Lipid metabolism
   00062 Fatty acid elongation
    K10248  ELOVL3; elongation of very long chain fatty acids protein 3
   01040 Biosynthesis of unsaturated fatty acids
    K10248  ELOVL3; elongation of very long chain fatty acids protein 3
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01004 Lipid biosynthesis proteins
    K10248  ELOVL3; elongation of very long chain fatty acids protein 3
Enzymes [BR:ko01000]
2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.199  very-long-chain 3-oxoacyl-CoA synthase
     K10248  ELOVL3; elongation of very long chain fatty acids protein 3
Lipid biosynthesis proteins [BR:ko01004]
Elongase
  Unclassified
   K10248  ELOVL3; elongation of very long chain fatty acids protein 3

Other DBs

RN:	R09419 R10825

GO:

0009922

Genes

HSA:	83401(ELOVL3)

PTR:	745450(ELOVL3)

PPS:	100984036(ELOVL3)

GGO:	101130310(ELOVL3)

PON:	100461280(ELOVL3)

NLE:	100590122(ELOVL3)

MCC:	712927(ELOVL3)

MCF:	102118797(ELOVL3)

MTHB:

126962765

CSAB:

103216428(ELOVL3)

CATY:

105581876(ELOVL3)

PANU:

101019670(ELOVL3)

TGE:	112631815(ELOVL3)

RRO:	104656512(ELOVL3)

RBB:	108515074(ELOVL3)

TFN:	117067743(ELOVL3)

PTEH:

111538700(ELOVL3)

CANG:

105507108(ELOVL3)

CJC:	100395729(ELOVL3)

SBQ:	101046575(ELOVL3)

CSYR:

103249813(ELOVL3)

MMUR:

105874147(ELOVL3)

LCAT:

123649723(ELOVL3)

PCOQ:

105824292(ELOVL3)

OGA:	100959844(ELOVL3)

MMU:	12686(Elovl3)

MCAL:

110285710(Elovl3)

MPAH:

110334812(Elovl3)

RNO:	309449(Elovl3)

MCOC:

116103941(Elovl3)

MUN:	110556825(Elovl3)

CGE:	100774317(Elovl3)

MAUA:

101833021(Elovl3)

PLEU:

114696713 114708115

MORG:

121453775(Elovl3)

MFOT:

126503016

AAMP:

119805978(Elovl3)

NGI:	103744016(Elovl3)

HGL:	101710549(Elovl3)

CPOC:

100718611(Elovl3)

CCAN:

109691307(Elovl3)

DORD:

105986595(Elovl3)

DSP:	122116028(Elovl3)

NCAR:

124985837

OCU:

100344001

OPI:	101521208(ELOVL3)

TUP:	102494220(ELOVL3)

GVR:	103588096(ELOVL3)

CFA:	486855(ELOVL3)

CLUD:

112672237(ELOVL3)

VVP:	112917776(ELOVL3)

VLG:	121483603(ELOVL3)

AML:	100474267(ELOVL3)

UMR:	103680399(ELOVL3)

UAH:	113251865(ELOVL3)

UAR:	123795837(ELOVL3)

ELK:

111145439

LLV:

125084496

MPUF:

101682460(ELOVL3)

ORO:	101380206(ELOVL3)

EJU:	114205187(ELOVL3)

ZCA:	113923466(ELOVL3)

MLX:	118020836(ELOVL3)

NSU:	110589606(ELOVL3)

LWW:	102749635(ELOVL3)

FCA:	101101255(ELOVL3)

PYU:	121037156(ELOVL3)

PBG:	122493178(ELOVL3)

LRUF:

124506785

PTG:	102960047(ELOVL3)

PPAD:

109272814(ELOVL3)

AJU:	106966965(ELOVL3)

HHV:	120239610(ELOVL3)

BTA:	539782(ELOVL3)

BOM:	102275177(ELOVL3)

BIU:	109579009(ELOVL3)

BBUB:

102391298(ELOVL3)

BBIS:

105002680(ELOVL3)

CHX:	102189456(ELOVL3)

OAS:	101106896(ELOVL3)

ODA:	120873564(ELOVL3)

CCAD:

122445982(ELOVL3)

SSC:	100155434(ELOVL3)

CFR:	102515080(ELOVL3)

CBAI:

105081711(ELOVL3)

CDK:	105084349(ELOVL3)

VPC:	102545322(ELOVL3)

BACU:

103019331(ELOVL3)

LVE:	103075618(ELOVL3)

OOR:	101271502(ELOVL3)

DLE:	111172622(ELOVL3)

PCAD:

102981849(ELOVL3)

PSIU:

116742006(ELOVL3)

ECB:	100060081(ELOVL3)

EPZ:	103541062(ELOVL3)

EAI:	106837910 106837922 123278649

MYB:	102242009(ELOVL3)

MYD:	102768695(ELOVL3)

MMYO:

118669810(ELOVL3)

MLF:	102436284(ELOVL3)

MNA:	107542561(ELOVL3)

PKL:	118718922(ELOVL3)

HAI:	109379595(ELOVL3)

DRO:	112300465(ELOVL3)

SHON:

118999478(ELOVL3)

AJM:	119059680(ELOVL3)

PDIC:

114497048(ELOVL3)

PHAS:

123829038(ELOVL3)

MMF:	118632504(ELOVL3)

RFQ:	117036338(ELOVL3)

PALE:

102885120(ELOVL3)

PGIG:

120609160(ELOVL3)

PVP:	105304658(ELOVL3)

RAY:	107515586(ELOVL3)

MJV:	108405923(ELOVL3)

TOD:	119233875(ELOVL3)

SARA:

101557821(ELOVL3)

LAV:	100662376(ELOVL3)

TMU:

101351910

ETF:	101655517(ELOVL3)

DNM:	101416428(ELOVL3)

MDO:	100029282(ELOVL3)

GAS:	123236245(ELOVL3)

SHR:	100923989(ELOVL3)

PCW:	110192158(ELOVL3)

OAA:	100080155(ELOVL3)

CSCU:

111631306

» show all

Reference

PMID:20937905

Authors

Ohno Y, Suto S, Yamanaka M, Mizutani Y, Mitsutake S, Igarashi Y, Sassa T, Kihara A

Title

ELOVL1 production of C24 acyl-CoAs is linked to C24 sphingolipid synthesis.

Journal

Proc Natl Acad Sci U S A 107:18439-44 (2010)
DOI:10.1073/pnas.1005572107

LinkDB

ORTHOLOGY: K10249

Entry

K10249                      KO

Symbol

ELOVL4

Name

elongation of very long chain fatty acids protein 4 [EC:2.3.1.199]

Pathway

map00062

Fatty acid elongation

map01040

Biosynthesis of unsaturated fatty acids

map01100

Metabolic pathways

map01110

Biosynthesis of secondary metabolites

map01212

Fatty acid metabolism

Module

M00415

Fatty acid elongation in endoplasmic reticulum

Disease

H00063

Spinocerebellar ataxia (SCA)

H00819

Stargardt disease

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09103 Lipid metabolism
   00062 Fatty acid elongation
    K10249  ELOVL4; elongation of very long chain fatty acids protein 4
   01040 Biosynthesis of unsaturated fatty acids
    K10249  ELOVL4; elongation of very long chain fatty acids protein 4
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01004 Lipid biosynthesis proteins
    K10249  ELOVL4; elongation of very long chain fatty acids protein 4
Enzymes [BR:ko01000]
2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.199  very-long-chain 3-oxoacyl-CoA synthase
     K10249  ELOVL4; elongation of very long chain fatty acids protein 4
Lipid biosynthesis proteins [BR:ko01004]
Elongase
  PUFA
   K10249  ELOVL4; elongation of very long chain fatty acids protein 4

Other DBs

RN:	R09419 R10825

GO:

0009922

Genes

HSA:	6785(ELOVL4)

PTR:	462842(ELOVL4)

PPS:	100968249(ELOVL4)

GGO:	101129175(ELOVL4)

PON:	100440564(ELOVL4)

NLE:	100596130(ELOVL4)

MCC:	692070(ELOVL4)

MCF:	102138130(ELOVL4)

MTHB:

126953904

CSAB:

103239978(ELOVL4)

CATY:

105588064(ELOVL4)

PANU:

101000813(ELOVL4)

TGE:	112623386(ELOVL4)

RRO:	104682056(ELOVL4)

RBB:	108512609(ELOVL4)

TFN:	117097580(ELOVL4)

PTEH:

111549912(ELOVL4)

CANG:

105517657(ELOVL4)

CJC:	100396385(ELOVL4)

SBQ:	101034271(ELOVL4)

CSYR:

103265685(ELOVL4)

MMUR:

105873835(ELOVL4)

LCAT:

123633022(ELOVL4)

PCOQ:

105811768(ELOVL4)

OGA:	100952326(ELOVL4)

MMU:	83603(Elovl4)

MCAL:

110302312(Elovl4)

MPAH:

110328059(Elovl4)

RNO:	315851(Elovl4)

MCOC:

116072024(Elovl4)

MUN:	110546457(Elovl4)

CGE:	100774858(Elovl4)

MAUA:

101838403(Elovl4)

PLEU:

114697277(Elovl4)

MORG:

121466218(Elovl4)

MFOT:

126491674

AAMP:

119809624(Elovl4)

NGI:	103729172(Elovl4)

HGL:	101701805(Elovl4)

CPOC:

100720101(Elovl4)

CCAN:

109698009(Elovl4)

DORD:

105997737(Elovl4)

DSP:	122100757(Elovl4)

NCAR:

124989637

OCU:

100353429

OPI:	101526298(ELOVL4)

TUP:	102475313(ELOVL4) 102489276

GVR:	103598555(ELOVL4)

CFA:	481894(ELOVL4)

CLUD:

112658379(ELOVL4)

VVP:	112926381(ELOVL4)

VLG:	121473352(ELOVL4)

AML:	100475550(ELOVL4)

UMR:	103657419(ELOVL4)

UAH:	113261082(ELOVL4)

UAR:	123797477(ELOVL4)

ELK:

111147687

LLV:

125102784

MPUF:

101677575(ELOVL4)

ORO:	101379613(ELOVL4)

EJU:	114213082(ELOVL4)

ZCA:	113927467(ELOVL4)

MLX:	118000749(ELOVL4)

NSU:	110583037(ELOVL4)

LWW:	102739051(ELOVL4)

FCA:	101101313(ELOVL4) 102900369

PYU:	121021949 121029706(ELOVL4)

PBG:	122489723(ELOVL4)

LRUF:

124529064

PTG:	102960657(ELOVL4)

PPAD:

109263327(ELOVL4) 109276187

AJU:	106976574(ELOVL4)

HHV:	120219599(ELOVL4)

BTA:	532015(ELOVL4)

BOM:	102284782(ELOVL4)

BIU:	109558607 109563726(ELOVL4)

BBUB:

102398668(ELOVL4) 102414871

BBIS:

104992340 104999704(ELOVL4)

CHX:	102172444(ELOVL4) 106502144

OAS:	101113417(ELOVL4) 105608607

ODA:	120857778 120862914(ELOVL4)

CCAD:

122422860(ELOVL4)

SSC:	100511670(ELOVL4)

CFR:	102512198(ELOVL4)

CBAI:

105083093(ELOVL4)

CDK:	105104040(ELOVL4)

VPC:	102530570(ELOVL4)

BACU:

103011283(ELOVL4)

LVE:	103083406(ELOVL4)

OOR:	101283409(ELOVL4)

DLE:	111183214(ELOVL4)

PCAD:

102992831(ELOVL4)

PSIU:

116763741(ELOVL4)

ECB:	100069512(ELOVL4)

EPZ:	103548486(ELOVL4)

EAI:	106842949(ELOVL4)

MYB:	102256207(ELOVL4)

MYD:	102756238(ELOVL4)

MMYO:

118659975(ELOVL4)

MLF:	102430517(ELOVL4)

MNA:	107532845(ELOVL4)

PKL:	118705051(ELOVL4)

HAI:	109387807(ELOVL4)

DRO:	112319333(ELOVL4)

SHON:

118982355(ELOVL4)

AJM:	119047449(ELOVL4)

PDIC:

114495313(ELOVL4)

PHAS:

123821311(ELOVL4)

MMF:	118621972(ELOVL4)

RFQ:	117020585(ELOVL4)

PALE:

102897900(ELOVL4)

PGIG:

120594878(ELOVL4)

PVP:	105295295(ELOVL4)

RAY:	107513206(ELOVL4)

MJV:	108390554(ELOVL4)

TOD:	119247051 119252643(ELOVL4)

SARA:

101540217 101555644(ELOVL4)

LAV:	100654940(ELOVL4)

TMU:

101360177

ETF:	101649014(ELOVL4) 101650210

DNM:	101417364(ELOVL4)

MDO:	100017828(ELOVL4)

GAS:	123246987(ELOVL4)

SHR:	100928562(ELOVL4)

PCW:	110200297(ELOVL4)

OAA:	100081381(ELOVL4)

GGA:	421850(ELOVL4)

PCOC:

116240605(ELOVL4)

MGP:	100546793(ELOVL4)

CJO:	107312020(ELOVL4)

NMEL:

110396530(ELOVL4)

APLA:

101790547(ELOVL4) 101801566

ACYG:

106046290 106048591(ELOVL4)

AFUL:

116487244(ELOVL4) 116491627

TGU:	100225997(ELOVL4) 100232706

LSR:	110475714 110476538(ELOVL4)

SCAN:

103819554 103822499(ELOVL4)

PMOA:

120507682 120512286(ELOVL4)

OTC:	121340012(ELOVL4) 121347842

PRUF:

121349667 121360507(ELOVL4)

GFR:	102040968 102044122(ELOVL4)

FAB:	101819154(ELOVL4) 101819804

PHI:	102102223 102114272(ELOVL4)

PMAJ:

107202280(ELOVL4) 107205111

CCAE:

111923378 111925784(ELOVL4)

CCW:	104692774(ELOVL4) 104696121

CBRC:

103621459(ELOVL4)

ETL:	114066535 114067169(ELOVL4)

ZAB:	102068802(ELOVL4) 102073313

ACHL:

103803186(ELOVL4) 103809207

FPG:	101919974(ELOVL4) 101921045

FCH:	102052860 102056363(ELOVL4)

CLV:	102095164 102097944(ELOVL4)

EGZ:	104124213 104132758(ELOVL4)

NNI:	104021788 104022023(ELOVL4)

PLET:

104617811(ELOVL4)

PCRI:

104025277 104031749(ELOVL4)

PCAO:

104043455 104044740(ELOVL4)

ACUN:

113477647(ELOVL4)

TALA:

104360148(ELOVL4) 104367355

PADL:

103917225 103924591(ELOVL4)

AFOR:

103901789(ELOVL4) 103906572

ACHC:

115352364 115353886(ELOVL4)

HALD:

104311677(ELOVL4) 104318704

HLE:	104830666(ELOVL4) 104836641

AGEN:

126046126 126047606

GCL:	127014793 127029033

CCRI:

104159678(ELOVL4) 104161521

CSTI:

104557670(ELOVL4) 104563843

EHS:

104504063

CMAC:

104480283(ELOVL4) 104483132

MUI:	104536818(ELOVL4) 104541399

FGA:	104081646(ELOVL4) 104082606

GSTE:

104257764 104260043(ELOVL4)

LDI:	104349694 104350388

MNB:	103769491(ELOVL4) 103770917

OHA:	104330427(ELOVL4) 104333015

NNT:	104413210(ELOVL4)

DPUB:

104306296 104306462(ELOVL4)

PGUU:

104461914(ELOVL4)

ACAR:

104519167(ELOVL4) 104525671

CPEA:

104393675(ELOVL4) 104395237

AVIT:

104277352(ELOVL4) 104279500

CVF:	104288676(ELOVL4) 104294602

CUCA:

104062673(ELOVL4) 104066618

TEO:	104371385 104372402

BRHI:

104489709(ELOVL4) 104498057

AAM:	106488771 106489580(ELOVL4)

AROW:

112977288(ELOVL4)

NPD:	112946604(ELOVL4)

TGT:	104576296(ELOVL4)

DNE:	112986815 112995862(ELOVL4)

SCAM:

104139949(ELOVL4) 104144410

ASN:	102373426(ELOVL4)

AMJ:	102573512(ELOVL4)

CPOO:

109311815(ELOVL4)

GGN:	109299921(ELOVL4)

PSS:	102446236(ELOVL4) 102463304 102463792

CMY:	102932502 102939512(ELOVL4)

CPIC:

101936216 101945122(ELOVL4)

TST:	117875153(ELOVL4) 117884455

CABI:

116814745 116821636(ELOVL4)

MRV:	120387927 120401491(ELOVL4)

ACS:	100558520(elovl4)

PVT:	110085734(ELOVL4) 110091506

SUND:

121917396 121917500

PBI:	103053806(ELOVL4)

PMUR:

107288224(ELOVL4)

CTIG:

120318927(ELOVL4)

TSR:	106545390(ELOVL4)

PGUT:

117674063(ELOVL4)

VKO:	123019106(ELOVL4)

PMUA:

114593897(ELOVL4)

ZVI:	118082307(ELOVL4)

GJA:	107121888(ELOVL4)

STOW:

125432126(ELOVL4)

XLA:	108717990(elovl4.S) 734428(MGC115163.L)

XTR:	100496222(elovl4) 101732387(MGC115163)

NPR:	108798588(ELOVL4) 108799010

RTEM:

120937062(ELOVL4) 120942957

BBUF:

120998143(ELOVL4) 121007669

BGAR:

122934727(ELOVL4) 122945123

DRE:	335732(elovl4b) 393769(elovl4a) 554145(elovl8b) 767653(elovl8a)

SRX:	107713923 107714853 107714912 107726252 107729115 107736802 107743843 107751851

SANH:

107657928 107664178 107679337 107688984 107689158 107689169 107697898 107699894

SGH:	107558740 107559048 107585829 107599298 107602526

CCAR:

109056939 109057708 109074280 109078047 109083719 109098404 109104065

CAUA:

113041298 113060065 113065652 113069873 113070943 113073634 113080378 113107111 113116554(elovl4) 113117539

PPRM:

120462689(elovl4a) 120463277(elovl4b) 120482279(elovl8b) 120482318 120482657(elovl8a)

MAMB:

125243429(elovl4a) 125251320(elovl8a) 125259753(elovl4b) 125279759(elovl8b)

IPU:	108265939(elovl8b) 108272628(elovl4a) 108275555(elovl4b)

PHYP:

113527000(elovl4) 113530681 113534933

SMEO:

124384255(elovl4a) 124398987(elovl4b) 124400514(elovl8b)

TFD:	113635322(elovl8b) 113644764(elovl4a) 113652986 125140010(elovl4b)

AMEX:

103026255 103035050(elovl4) 103039014

EEE:	113572917(elovl4)

TRU:	101065200 101072132 101075102

TNG:	GSTEN00020209G001 GSTEN00020666G001

LCO:	104918438 104925635(elovl4) 104926213

NCC:	104949334(elovl4) 104954092 104955465 104959623 104965520

CGOB:

115003755 115006739 115021097 115022399

ELY:	117253780 117253781 117253782 117266249(elovl4a) 117271271 117271718(elovl8a)

EFO:	125893672(elovl4a) 125895390 125895391 125895392 125896751 125901954(elovl8a)

PLEP:

121938512 121945960(elovl4a) 121951844(elovl8a) 121955350(elovl4b) 121962409

SLUC:

116035308(elovl4a) 116063264(elovl8b) 116063265 116066039(elovl4b)

ECRA:

117946521(elovl4a) 117950222 117950223 117961160(elovl4b)

ESP:	116690748 116694920 116694922 116706477

PFLV:

114556617 114561261 114561880 114572965

GAT:	120808234(elovl4b) 120810898(elovl4a) 120816429(elovl8a) 120824450 120824452

PPUG:

119195215 119197917(elovl4a) 119209845(elovl8a) 119216379 119216380

MSAM:

119897927(elovl4a) 119900839 119902999(elovl8a) 119909533 119918674

CUD:	121512371(elovl8b) 121513969(elovl4a) 121520238(elovl8a) 121521207(elovl4b)

ALAT:

119005759(elovl4a) 119010513(elovl8a) 119012478(elovl4b) 119028179(elovl8b)

MZE:	101477514 101479286 101481327 101483690 112431397 112431742 112433434 112433435 112434435 112434813 112434814 112436132 112436141

ONL:	100692024 100695278 100709135 100711736

OAU:	116309569 116313151(elovl8a) 116322620(elovl4a) 116333324(elovl8b)

OLA:	101158407 101161285 101165545 101168572

OML:	112136963(elovl8b) 112137624(elovl4b) 112143893(elovl4a) 112147416(elovl8a)

XMA:	102217542 102220842 102231820 102235415

XCO:	114142270 114146238 114151186 114158200

XHE:	116717447 116721893 116725152 116733654(elovl4)

PRET:

103457721 103463607 103478339 103479188

PFOR:

103135593 103136405 103138439 103142551 103144142

PLAI:

106949271 106952157 106953590 106963616

PMEI:

106917060 106922388 106923403 106923911

GAF:	122825162(elovl4b) 122831590(elovl4a) 122838225(elovl8b) 122841347(elovl8a)

CVG:	107081978 107089631 107091673 107097972

CTUL:

119776825(elovl8b) 119777108(elovl4a) 119788695 119793320(elovl8a)

GMU:	124866115(elovl4a) 124869435(elovl8a) 124874031(elovl8b) 124882353

NFU:	107378026(elovl4) 107378783 107380622 107393252 107393253 107393254

KMR:	108231727 108232315(elovl4a)

ALIM:

106513874 106514216 106520030(elovl4)

NWH:	119407924(elovl8b) 119410189(elovl4a) 119418132

AOCE:

111567654 111570221 111583908 111589079

MCEP:

124999388 125009325(elovl8b) 125010800(elovl8a) 125016463(elovl4a)

CSEM:

103380776(elovl4) 103388604 103393619

POV:	109625839 109632039 109632469(elovl4) 109641416

SSEN:

122775095 122780891(elovl8b) 122783916

HHIP:

117758890(elovl4b) 117759727(elovl8b) 117776180(elovl4a) 117778741(elovl8a)

HSP:	118099943(elovl4b) 118114362(elovl4a) 118118345(elovl8a) 124854741(elovl8b)

LCF:	108877346(elovl8b) 108883232(elovl8a) 108888589(elovl4a) 108893054 108896792(elovl4b)

SDU:	111227693 111232162 111239138 111239212

SLAL:

111653449 111656378 111658153 111672788

XGL:	120783758(elovl4a) 120789412(elovl4b) 120791203(elovl8b) 120799338(elovl8a)

HCQ:	109515526 109527839 109531419 109532073 109532074

BPEC:

110166812 110167734 110167755 110170367 110171410

MALB:

109952214 109958170 109964009

BSPL:

114843152(elovl4a) 114850078 114853907(elovl8b)

SASA:

100500788(elovl4) 106569295 106571493 106574012 106597446 106597646 106606161 106613536

STRU:

115151566 115157022 115158004 115174677 115187953 115191470

OTW:	112217684 112241696(elovl4a) 112246732 112250406 112250645 112261107(elovl8a)

OMY:	110520742(elovl4a) 110522328 110524051 110529127(elovl8a) 110529707 110536107 118936610

OGO:	123990847 123995183 123997400 123997412 124009955 124017637 124040667

ONE:	115101576 115107850 115108091 115109061 115113942 115139313

SALP:

111952983 111954525 111956896 111973471

SNH:	120019447 120024592 120038496 120039001 120053356 120054630 120055884

CCLU:

121533741 121535230(elovl8a) 121542575 121548833 121552473 121576556 121585947

ELS:	105017639(elovl4) 105023511 106023669

SFM:	108929205 108935055 108937440(elovl4)

PKI:	111844578 111851539

AANG:

118229157 118230650(elovl8a) 118230876

LOC:	102682287(elovl4) 102691887

PSPA:

121316262 121317389 121326473(elovl8b)

ARUT:

117403106 117411167 117417319(elovl8b)

PSEX:

120515001(elovl8b) 120525488(elovl4a)

LCM:	102346876 102364316(ELOVL4)

CMK:	103181830 103182793 103186183(elovl4a)

RTP:	109911942(elovl4) 109926904

BFO:	118413959 118413960 118431686

BBEL:

109476011 109482921 109482923

CIN:	100176701 100182495 100186020 619277(elo)

SCLV:

120329482 120329483 120331026 120332275

SPU:	588063 588095 593296

APLC:

110987689 110987690 110991136

AJC:	117106541 117108268 117108270 117110137

SKO:	100373013 100375515 100377822

DME:	Dmel_CG11801(Elo68beta) Dmel_CG17821(CG17821) Dmel_CG18609(CG18609) Dmel_CG32072(Elo68alpha)

DER:	6543867 6543868 6547301 6547302 6552258 6555308

DSE:	6605225 6605226 6609845

DSI:	Dsimw501_GD12826(Dsim_GD12826) Dsimw501_GD12827(Dsim_GD12827) Dsimw501_GD25362(Dsim_GD25362) Dsimw501_GD25363(Dsim_GD25363)

DYA:	Dyak_GE13887 Dyak_GE13888 Dyak_GE20238 Dyak_GE20239

DSR:	110178444 110178467 110185195 110185541

DPO:	4801488 4803747 4803748 6900500

DPE:	6588118 6590971 6591184 6596053

DMN:	108154307 108160217 108160218 108165290 117189875 117189876

DWI:	6638175 6646352 6651277

DGR:	6557120 6560812

DMO:	Dmoj_GI12398 Dmoj_GI20343 Dmoj_GI20347

DAZ:	108608759 108612257 108614900 108615720 108615721

DNV:	108650136 108652743 108652744 108653114 108653125

DHE:	111592737 111604234 111604241 111604271 111604278

DVI:

6623655

CCAT:

101456346 101457403 101457584 101457763 101457936 101458266

BOD:	106616941 106618532 106618535 106618537 106621943

RZE:	108360734 108360739 108376053 108377384

MDE:	101897164 101901465

SCAC:

106090812

LCQ:	111678936 111678979

AGA:	AgaP_AGAP003196 AgaP_AGAP005512 AgaP_AGAP008781 AgaP_AGAP010695 AgaP_AGAP013094 AgaP_AGAP013219

ACOZ:

120950250 120951809 120953377 120953514 120955012 120957431 120958195

AARA:

120902809

ASTE:

118503305

AAG:	5565720 5565723 5570004 5570274 5575618 5579662

AALB:

109408200 109408824 109409730 109411136 109422322 109423283 109431877 109621398 109622324 115266567

CQU:	CpipJ_CPIJ000106 CpipJ_CPIJ002114 CpipJ_CPIJ011025 CpipJ_CPIJ013819 CpipJ_CPIJ013820 CpipJ_CPIJ015711 CpipJ_CPIJ015712 CpipJ_CPIJ016352 CpipJ_CPIJ016353

CPII:

120415344 120415397 120418798 120421298 120423367 120424481 120427103 120428400 120431895

CNS:	116336979 116348985 116351671

BCOO:

119073702 119084199

AME:	411692 552205

ACER:

107994124

ALAB:

122718637

BIM:	100742966 100747691

BBIF:

BVK:

BVAN:

BTER:

BPYO:

CCAL:

108622032 108627087 108627143

OBB:	114878696 114879565

MGEN:

117222472 117222473 117227910

NMEA:

116434655

CGIG:

122401429

SOC:	105196410 105198876 105198878 105200079 105201228 105206101 105206102 105206542 105207288

MPHA:

105829987 105833246 105835664 105839655 105840549

AEC:	105146422 105150634

ACEP:

105617270 105627891 105627892

PBAR:

105429762 105431153

VEM:	105557442 105558649 105559046 105559509 105559720 105560982 105564001 105564052 105567243 105567412 105567510 105568169 105569921 105570472

HST:	105187097 105190301 105190837 112589569

DQU:	106743883 106746641

CFO:	105253415 105257376 112639251

FEX:	115234223 115235632 115240858 115246208

LHU:	105671817 105672220 105672722 105677477 105677950

PGC:	109852988 109856621 109861827

OBO:	105282540 105282586 105284449 105285820 105285821

PCF:	106784445 106790373

PFUC:

VPS:

NVI:

CSOL:

TPRE:

MDL:

CGLO:

FAS:

DAM:

AGIF:

CINS:

CCIN:

TCA:	654965 662823 664297

DPA:	109540565 109545552

SOY:

115876958

ATD:

109594942

CSET:

123316144 123318729 123320281

AGB:	108906873 108907150

LDC:

111509546

NVL:	108557524 108559523 108559544 108563106 108563110 108566796

APLN:

108738366

PPYR:

116165080 116176377

OTU:	111422939 111427613

BMOR:

101735457 101743614 101744268 101746391 101747016 105841414

BMAN:

114240073 114240101 114240149 114240665 114244054 114249331

MSEX:

115449531

DPL:	KGM_202674 KGM_204195 KGM_211376

BANY:

112047627

NIQ:

126768156

PMAC:

106709809 106709861 106709916 106709917 106709918 106709946 106720222 106721572

PPOT:

106100234 106103872 106105715

PXU:	106113414 106120257 106125239

PRAP:

110999618

PBX:

123711059

PNAP:

125059415

ZCE:	119828523 119831220 119831221 119833605

CCRC:

123691950

HAW:	110370450 110370836 110370977 110378596

HZE:

124632547

TNL:	113495429 113498727 113506913

SLIU:

111358538

OFU:

114353537

PXY:	105386866 105392258 105392946 105397924 105398220 105398445

CFEL:

113370560 113371081

API:	100160501 100569447 100569605 100571105 100571500 100574502 107884928

DNX:	107162281 107162291 107164108 107165138 107165310 107168528

AGS:	114119097 114119098 114122945 114122980 114124152 114124156

RMD:	113548558 113548560 113548561 113548811 113548877 113554712

BTAB:

109029930 109033839 109033905 109034811 109037307 109040551

DCI:

103518797

CLEC:

106664703 106666873

HHAL:

106679853 106680077

NLU:	111044453 111053931 111054984 111056778 111060032 111060917

PHU:	Phum_PHUM336650 Phum_PHUM432430

FOC:

TPAL:

ZNE:

CSEC:

SGRE:

FCD:	110841943 110851042

DPX:	DAPPUDRAFT_214082 DAPPUDRAFT_260977 DAPPUDRAFT_48753

DMK:	116916395 116917304 116926066

DPZ:	124313931 124315513 124336405 124341254

PVM:

PJA:

PCHN:

HAME:

PCLA:

PTRU:

HAZT:

EAF:	111710419 111716831

LSM:	121121675 121125779

PPOI:

119091644 119092004 119094982 119094983 119094984 119094986 119094987 119095026 119095034

ISC:	IscW_ISCW001195 IscW_ISCW002252 IscW_ISCW002253 IscW_ISCW003067 IscW_ISCW003068 IscW_ISCW003894 IscW_ISCW008976 IscW_ISCW010858 IscW_ISCW013892 IscW_ISCW015227 IscW_ISCW015231 IscW_ISCW015233 IscW_ISCW015239 IscW_ISCW019365 IscW_ISCW023550

VDE:	111242847 111243262 111245104 111245155 111247560 111249590 111250909 111252228 111253930 111254326 111255421

VJA:	111259184 111261149 111261407 111261905 111262758 111266990 111267023 111267917 111268524 111269132 111271235

TUT:	107359173 107364319 107369823

DPTE:

113789045 113794805 113797236 113798159 113799467

DFR:	124490172 124497939 124500194

CSCU:

111631295 111640797

PTEP:

107436347 107441687 107442150 107442153 107442154 107442273 107442809 107443297 107443298 107445008 107450928 107451291 107453608 110283505 122269995

SDM:

118192113

HRO:	HELRODRAFT_105761 HELRODRAFT_188628

LGI:	LOTGIDRAFT_214031

PCAN:

112558670 112558671 112573450 112573605 112573626 112573795

BGT:	106062435 106062718 106062719 106064359 106064582

GAE:	121374260 121376280 121379297 121380673 121381012

HRF:	124133198 124133200 124133201 124133232 124142905 124142906

HRJ:	124253677 124253678 124262022 124262037 124284854 124284873 124290764

CRG:	105317417 105320683 105324573 105342352 105344648 105344649 117684788

MYI:	110445441 110445491 110461521 110461559

PMAX:

117326221 117326222 117335564 117336871

MMER:

123524388 123537141 123537142 123547757

OBI:

106879253

OSN:	115218355 115223492

LAK:	106152865 106152867 106173959 106173973 106182105

SMM:	Smp_051810

SHX:	MS3_00007908(ELOVL4)

NVE:	116604103 5497638 5500958 5508941 5521025

EPA:	110238283 110238284

ATEN:

116304036 116304037 116305053

ADF:	107331551 107341379 107341401 107341402 107341403 107341404

AMIL:

114974467 114974528 114975126 114975144 114975162 114975644

PDAM:

113684907 113684908

SPIS:

111321466 111321467

DGT:	114522149 114525174 114527416 114529533 114531233 114535789 114535790 114535795 114540996

XEN:	124454097 124454099 124454100 124454323 124454645 124454683 124455744 124457464

HMG:	100198256 100200336 100210039 100211332

TAD:	TRIADDRAFT_19695 TRIADDRAFT_24481

AQU:

100638269

PPP:

112294502

OLU:	OSTLU_33532 OSTLU_48622

OTA:	OT_ostta02g00200 OT_ostta09g02530

BPG:	Bathy14g02650

MIS:	MICPUN_107425(ELO1) MICPUN_88101

MPP:	MICPUCDRAFT_40609 MICPUCDRAFT_6532

MBR:	MONBRDRAFT_29385 MONBRDRAFT_34287 MONBRDRAFT_34679

SRE:	PTSG_05847 PTSG_08487

DDI:	DDB_G0270312 DDB_G0271066

DPP:	DICPUDRAFT_27790 DICPUDRAFT_33776

DFA:

DFA_00445

ACAN:

ACA1_167040

PFA:	PF3D7_0605900

PFD:	PFDG_03954

PFH:	PFHG_01226

PREI:

PRSY57_0604500

PGAB:

PGSY75_0605900

PYO:	PY17X_0106200

PCB:	PCHAS_0105300

PBE:	PBANKA_0104700

PVV:	PVVCY_0100600

PKN:	PKNH_1144300

PVX:	PVX_113465

PCY:	PCYB_115050

BBIG:

BBBOND_0005930

TGO:	TGME49_242380

PTI:	PHATRDRAFT_9255

FCY:	FRACYDRAFT_177742 FRACYDRAFT_277401

TPS:	THAPSDRAFT_93

PIF:	PITG_13178 PITG_16760 PITG_16761

PSOJ:

PHYSODRAFT_352093 PHYSODRAFT_354308

SPAR:

SPRG_08322 SPRG_09463

GTT:	GUITHDRAFT_98336

LMA:	LMJF_32_1160

LIF:	LINJ_32_1220

LDO:	LDBPK_321220

LMI:	LMXM_31_1160

LBZ:	LBRM_32_1310

LPAN:

LPMP_321230

» show all

Reference

PMID:20937905

Authors

Ohno Y, Suto S, Yamanaka M, Mizutani Y, Mitsutake S, Igarashi Y, Sassa T, Kihara A

Title

ELOVL1 production of C24 acyl-CoAs is linked to C24 sphingolipid synthesis.

Journal

Proc Natl Acad Sci U S A 107:18439-44 (2010)
DOI:10.1073/pnas.1005572107

LinkDB

ORTHOLOGY: K10244

Entry

K10244                      KO

Symbol

ELOVL5

Name

elongation of very long chain fatty acids protein 5 [EC:2.3.1.199]

Pathway

map00062

Fatty acid elongation

map01040

Biosynthesis of unsaturated fatty acids

map01100

Metabolic pathways

map01110

Biosynthesis of secondary metabolites

map01212

Fatty acid metabolism

Module

M00415

Fatty acid elongation in endoplasmic reticulum

Disease

H00063

Spinocerebellar ataxia (SCA)

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09103 Lipid metabolism
   00062 Fatty acid elongation
    K10244  ELOVL5; elongation of very long chain fatty acids protein 5
   01040 Biosynthesis of unsaturated fatty acids
    K10244  ELOVL5; elongation of very long chain fatty acids protein 5
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01004 Lipid biosynthesis proteins
    K10244  ELOVL5; elongation of very long chain fatty acids protein 5
Enzymes [BR:ko01000]
2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.199  very-long-chain 3-oxoacyl-CoA synthase
     K10244  ELOVL5; elongation of very long chain fatty acids protein 5
Lipid biosynthesis proteins [BR:ko01004]
Elongase
  PUFA
   K10244  ELOVL5; elongation of very long chain fatty acids protein 5

Other DBs

RN:	R09419 R10825

GO:

0009922

Genes

HSA:	60481(ELOVL5)

PTR:	472038(ELOVL5)

PPS:	100995722(ELOVL5)

GGO:	101124844(ELOVL5)

PON:	100174198(ELOVL5)

NLE:	100580650(ELOVL5)

MCC:	712243(ELOVL5)

MCF:	102140887(ELOVL5)

MTHB:

126953686

CSAB:

103221342(ELOVL5)

CATY:

105590290(ELOVL5)

PANU:

101005826(ELOVL5)

TGE:	112622045(ELOVL5)

RRO:	104662849(ELOVL5)

RBB:	108519311(ELOVL5)

TFN:	117087368(ELOVL5)

PTEH:

111549745(ELOVL5)

CANG:

105524811(ELOVL5)

CJC:	100403530(ELOVL5)

SBQ:	101047560(ELOVL5)

CSYR:

103262314(ELOVL5)

MMUR:

105880018(ELOVL5)

LCAT:

123632961(ELOVL5)

PCOQ:

105813801(ELOVL5)

OGA:	100958384(ELOVL5)

MMU:	68801(Elovl5)

MCAL:

110301217(Elovl5)

MPAH:

110327330(Elovl5)

RNO:	171400(Elovl5)

MCOC:

116071949(Elovl5)

MUN:	110552273(Elovl5)

CGE:	100753555(Elovl5)

MAUA:

101844560(Elovl5)

PLEU:

114685257(Elovl5)

MORG:

121466178(Elovl5)

MFOT:

126490023

AAMP:

119809075(Elovl5)

NGI:	103736929(Elovl5)

HGL:	101717423(Elovl5)

CPOC:

100727016(Elovl5)

CCAN:

109696848(Elovl5)

DORD:

105987817(Elovl5)

DSP:	122101564(Elovl5)

NCAR:

124988388

OCU:

100342638

OPI:	101531153(ELOVL5)

TUP:	102476603(ELOVL5)

GVR:	103608501(ELOVL5)

CFA:	610377(ELOVL5)

CLUD:

112641760(ELOVL5)

VVP:	112914072(ELOVL5)

VLG:	121473335(ELOVL5)

AML:	100465764(ELOVL5)

UMR:	103663993(ELOVL5)

UAH:	113261178(ELOVL5)

UAR:	123795635(ELOVL5)

ELK:

111152367

LLV:

125102103

MPUF:

101691109(ELOVL5)

ORO:	101373589(ELOVL5)

EJU:	114204413(ELOVL5)

ZCA:	113926511(ELOVL5)

MLX:	118001399(ELOVL5)

NSU:	110582013(ELOVL5)

LWW:	102746610(ELOVL5)

FCA:	101086147(ELOVL5)

PYU:	121029593(ELOVL5)

PBG:	122489634(ELOVL5)

LRUF:

124529429

PTG:	102960399(ELOVL5)

PPAD:

109271763(ELOVL5)

AJU:	106973074(ELOVL5)

HHV:	120224694(ELOVL5)

BTA:	617293(ELOVL5)

BOM:	102272645(ELOVL5)

BIU:	109577190(ELOVL5)

BBUB:

102389407(ELOVL5)

BBIS:

104992399(ELOVL5)

CHX:	100861282(ELOVL5)

OAS:	101108431(ELOVL5)

ODA:	120870010(ELOVL5)

CCAD:

122429168(ELOVL5)

SSC:	100171403(ELOVL5)

CFR:	102515774(ELOVL5)

CBAI:

105083873(ELOVL5)

CDK:	105099539(ELOVL5)

VPC:	102526724(ELOVL5)

BACU:

103006755(ELOVL5)

LVE:	103086524(ELOVL5)

OOR:	101275572(ELOVL5)

DLE:	111178923(ELOVL5)

PCAD:

102982337(ELOVL5)

PSIU:

116762088(ELOVL5)

ECB:	100069400(ELOVL5)

EPZ:	103553254(ELOVL5)

EAI:	106845574(ELOVL5)

MYB:	102260152(ELOVL5)

MYD:	102762453(ELOVL5)

MMYO:

118659887(ELOVL5)

MLF:	102432747(ELOVL5)

MNA:	107525817(ELOVL5)

PKL:	118705204(ELOVL5)

HAI:	109396355(ELOVL5)

DRO:	112302283(ELOVL5)

SHON:

118992908(ELOVL5)

AJM:	119059750(ELOVL5)

PDIC:

114494244(ELOVL5)

PHAS:

123821743(ELOVL5)

MMF:	118621131(ELOVL5)

RFQ:	117017122(ELOVL5)

PALE:

102895992(ELOVL5)

PGIG:

120594929(ELOVL5)

PVP:	105304803(ELOVL5)

RAY:	107515261(ELOVL5)

MJV:	108394961(ELOVL5)

TOD:	119252568(ELOVL5)

SARA:

101537184(ELOVL5)

LAV:	100669438(ELOVL5)

TMU:

101340775

ETF:	101640932(ELOVL5)

DNM:	101440791(ELOVL5)

MDO:	100014197(ELOVL5)

GAS:	123247069(ELOVL5)

SHR:	100927609(ELOVL5)

PCW:	110213533(ELOVL5)

OAA:	100089631(ELOVL5)

GGA:	428646(ELOVL5)

PCOC:

116240744(ELOVL5)

MGP:	100540425(ELOVL5)

CJO:	107312117(ELOVL5)

NMEL:

110396020(ELOVL5)

APLA:

101795561(ELOVL5)

ACYG:

106030431(ELOVL5)

AFUL:

116488238(ELOVL5)

TGU:	100230721(ELOVL5)

LSR:	110482203(ELOVL5)

SCAN:

103820027(ELOVL5)

PMOA:

120510928(ELOVL5)

OTC:	121339121(ELOVL5)

PRUF:

121358889(ELOVL5)

GFR:	102035472(ELOVL5)

FAB:	101814943(ELOVL5)

PHI:	102104380(ELOVL5)

PMAJ:

107201946(ELOVL5)

CCAE:

111925884(ELOVL5)

CCW:	104693518(ELOVL5)

CBRC:

103619151(ELOVL5)

ETL:	114064901(ELOVL5)

ZAB:	102065705(ELOVL5)

ACHL:

103807404(ELOVL5)

FPG:	101924954(ELOVL5)

FCH:	102049021(ELOVL5)

CLV:	102093572(ELOVL5)

EGZ:	104126226(ELOVL5)

NNI:	104009370(ELOVL5)

PLET:

104621907(ELOVL5)

PCRI:

104029075(ELOVL5)

PCAO:

104042878(ELOVL5)

ACUN:

113478094(ELOVL5)

TALA:

104357586(ELOVL5)

PADL:

103924627(ELOVL5)

AFOR:

103906614(ELOVL5)

ACHC:

115351170(ELOVL5)

HALD:

104324972(ELOVL5)

HLE:	104827825(ELOVL5)

AGEN:

126046685

GCL:

127014715

CCRI:

104169481(ELOVL5)

CSTI:

104556088(ELOVL5)

EHS:	104514699(ELOVL5)

CMAC:

104486106(ELOVL5)

MUI:	104544973(ELOVL5)

FGA:	104083428(ELOVL5)

GSTE:

104251978(ELOVL5)

LDI:	104345075(ELOVL5)

MNB:	103775823(ELOVL5)

OHA:	104336489(ELOVL5)

NNT:	104402039(ELOVL5)

DPUB:

104303530(ELOVL5)

PGUU:

104467380(ELOVL5)

ACAR:

104531790(ELOVL5)

CPEA:

104390094(ELOVL5)

AVIT:

104272372(ELOVL5)

CVF:	104283897(ELOVL5)

CUCA:

104065326(ELOVL5)

TEO:	104378558(ELOVL5)

BRHI:

104494193(ELOVL5)

AAM:	106493256(ELOVL5)

AROW:

112975719(ELOVL5)

NPD:	112943149(ELOVL5)

TGT:	104568055(ELOVL5)

DNE:	112984881(ELOVL5)

SCAM:

104151944(ELOVL5)

ASN:	102370472(ELOVL5)

AMJ:	102574818(ELOVL5)

CPOO:

109311732(ELOVL5)

GGN:	109300003(ELOVL5)

PSS:	102454353(ELOVL5)

CMY:	102933860(ELOVL5)

CPIC:

101936469(ELOVL5)

TST:	117875230(ELOVL5)

CABI:

116815555(ELOVL5)

MRV:	120400629(ELOVL5)

ACS:	100552106(elovl5)

PVT:	110090240(ELOVL5)

SUND:

121935680(ELOVL5)

PBI:	103059591(ELOVL5)

PMUR:

107292159(ELOVL5)

CTIG:

120297561(ELOVL5)

TSR:	106551605(ELOVL5)

PGUT:

117676906(ELOVL5)

VKO:	123019074(ELOVL5)

PMUA:

114593823(ELOVL5)

ZVI:	118082365(ELOVL5)

GJA:	107121119(ELOVL5)

STOW:

125432979(ELOVL5)

XLA:	734710(elovl5.L) 734950(elovl5.S)

XTR:	496694(elovl5)

NPR:	108788957(ELOVL5)

RTEM:

120936979(ELOVL5)

BBUF:

120998080(ELOVL5)

BGAR:

122934074(ELOVL5)

DRE:	393425(elovl5)

SRX:	107712343 107751352

SANH:

107664697 107688786

SGH:	107570555(elovl5) 107597698 107597699

CCAR:

109082410 109102773

CAUA:

113057358 113113012

PPRM:

120492356(elovl5)

MAMB:

125277509(elovl5)

IPU:	100528842(elovl5)

PHYP:

113541999(elovl5)

SMEO:

124399870(elovl5)

TFD:	113655261(elovl5)

AMEX:

103046943(elovl5)

EEE:	113587735(elovl5)

TRU:	101070965(elovl5)

TNG:	GSTEN00030674G001

LCO:	104939717(elovl5)

NCC:	104948422(elovl5)

CGOB:

115019963(elovl5)

ELY:	117248502(elovl5)

EFO:	125903705(elovl5)

PLEP:

121954467(elovl5)

SLUC:

116052826(elovl5)

ECRA:

117960246(elovl5)

ESP:	116705607(elovl5)

PFLV:

114572011(elovl5)

GAT:	120820308(elovl5)

PPUG:

119214089(elovl5)

MSAM:

119917324(elovl5)

CUD:	121510921(elovl5)

ALAT:

119033376(elovl5)

MZE:	101471581(elovl5)

ONL:	100534548(elovl5)

OAU:	116322738(elovl5)

OLA:	101168981(elovl5)

OML:	112161638(elovl5)

XMA:	102219934(elovl5)

XCO:	114137975(elovl5)

XHE:	116713019(elovl5)

PRET:

103476995(elovl5)

PFOR:

103134067(elovl5)

PLAI:

106964616(elovl5)

PMEI:

106914800(elovl5)

GAF:	122842335(elovl5)

CVG:	107084573(elovl5)

CTUL:

119790683(elovl5)

GMU:	124858684(elovl5)

NFU:	107396604(elovl5)

KMR:	108234123(elovl5)

ALIM:

106523809(elovl5)

NWH:	119411882(elovl5)

AOCE:

111566479(elovl5)

MCEP:

125019128(elovl5)

CSEM:

103387417(elovl5)

POV:	109629770(elovl5)

SSEN:

122781485(elovl5)

HHIP:

117775994(elovl5)

HSP:	118119102(elovl5)

LCF:

108891101

SDU:	111234893(elovl5)

SLAL:

111656674(elovl5)

XGL:	120796080(elovl5)

HCQ:	109516202(elovl5)

BPEC:

110157194(elovl5)

MALB:

109961922(elovl5)

BSPL:

114841771(elovl5)

SASA:

100136433(elvol5a) 100192340(elovl5b)

STRU:

115153439 115201611

OTW:	112224640(elovl5) 112256952 112257478

OMY:	100136665 110499383(elovl5)

OGO:	124038410 124040357(elovl5)

ONE:	115113038 115144411

SALP:

111968106(elovl5) 111978130

SNH:	120029333(elovl5) 120046642

CCLU:

121547142(elovl5) 121575133

ELS:	105021354(elovl5)

SFM:	108932843(elovl5)

PKI:	111852825(elovl5)

AANG:

118218449(elovl5)

LOC:	102687455(elovl5)

PSPA:

121315755 121316855(elovl5)

ARUT:

117403386 117411440(elovl5)

PSEX:

120516530(elovl5)

LCM:	102345809(ELOVL5)

CMK:	103179003(elovl5)

RTP:	109934838(elovl5)

BFO:

BBEL:

SPU:

SKO:

LSM:

RSAN:

VDE:	111242988 111246268 111252227

VJA:	111261597 111267022 111272289

DFR:

124497422

HRO:	HELRODRAFT_63042

GAE:

121375052

HRJ:	124291735 124291736

CRG:

105348990

MYI:	110442172 110444690 110453659

PMAX:

MMER:

ADF:

AMIL:

PDAM:

SPIS:

PPP:	112274830 112295738

BPG:	Bathy10g01990

» show all

Reference

PMID:10970790

Authors

Leonard AE, Bobik EG, Dorado J, Kroeger PE, Chuang LT, Thurmond JM, Parker-Barnes JM, Das T, Huang YS, Mukerji P

Title

Cloning of a human cDNA encoding a novel enzyme involved in the elongation of long-chain polyunsaturated fatty acids.

Journal

Biochem J 350 Pt 3:765-70 (2000)
DOI:10.1042/bj3500765

Sequence

[hsa:60481]

LinkDB

ORTHOLOGY: K10203

Entry

K10203                      KO

Symbol

ELOVL6

Name

elongation of very long chain fatty acids protein 6 [EC:2.3.1.199]

Pathway

map00062

Fatty acid elongation

map01040

Biosynthesis of unsaturated fatty acids

map01100

Metabolic pathways

map01110

Biosynthesis of secondary metabolites

map01212

Fatty acid metabolism

Module

M00415

Fatty acid elongation in endoplasmic reticulum

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09103 Lipid metabolism
   00062 Fatty acid elongation
    K10203  ELOVL6; elongation of very long chain fatty acids protein 6
   01040 Biosynthesis of unsaturated fatty acids
    K10203  ELOVL6; elongation of very long chain fatty acids protein 6
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01004 Lipid biosynthesis proteins
    K10203  ELOVL6; elongation of very long chain fatty acids protein 6
Enzymes [BR:ko01000]
2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.199  very-long-chain 3-oxoacyl-CoA synthase
     K10203  ELOVL6; elongation of very long chain fatty acids protein 6
Lipid biosynthesis proteins [BR:ko01004]
Elongase
  PUFA
   K10203  ELOVL6; elongation of very long chain fatty acids protein 6

Other DBs

RN:	R07758 R07762 R09419 R10825

GO:

0009922

Genes

HSA:	79071(ELOVL6)

PTR:	461436(ELOVL6)

PPS:	100976431(ELOVL6)

GGO:	101151646(ELOVL6)

PON:	100456341(ELOVL6) 112129932

NLE:	100588402(ELOVL6)

MCC:	698870(ELOVL6)

MCF:	101926474(ELOVL6)

MTHB:

126954944

CSAB:

103236116(ELOVL6)

CATY:

105571437(ELOVL6)

PANU:

100999068(ELOVL6)

TGE:	112625217(ELOVL6)

RRO:	104682423(ELOVL6)

RBB:	108541021(ELOVL6)

TFN:	117085788(ELOVL6)

PTEH:

111547892(ELOVL6)

CANG:

105514421(ELOVL6)

CJC:	100386849(ELOVL6)

SBQ:	101044283(ELOVL6)

CSYR:

103267941(ELOVL6)

MMUR:

105872303(ELOVL6)

LCAT:

123627757(ELOVL6)

PCOQ:

105818949(ELOVL6)

OGA:	100952865(ELOVL6)

MMU:	170439(Elovl6)

MCAL:

110291156(Elovl6) 110308469

MPAH:

110320278(Elovl6)

RNO:	171402(Elovl6)

MCOC:

116093771(Elovl6)

MUN:	110553186(Elovl6)

CGE:

100763438

MAUA:

101830630(Elovl6) 121134770

PLEU:

114682669(Elovl6)

MORG:

121444933(Elovl6)

MFOT:

126497557

AAMP:

119801493(Elovl6)

NGI:	103742388(Elovl6)

HGL:	101721348(Elovl6)

CPOC:

100718388(Elovl6)

CCAN:

109700926(Elovl6)

DORD:

105991137(Elovl6)

DSP:	122127219(Elovl6)

NCAR:

124994652

OCU:

100358451

OPI:	101527670(ELOVL6)

TUP:	102483326(ELOVL6)

GVR:	103588496(ELOVL6)

CFA:	487900(ELOVL6)

CLUD:

112671649(ELOVL6)

VVP:	112934201(ELOVL6)

VLG:	121493750(ELOVL6)

AML:	100465578(ELOVL6)

UMR:	103661747(ELOVL6)

UAH:	113255564(ELOVL6)

UAR:	123793356(ELOVL6)

ELK:

111155573

LLV:

125093284

MPUF:

101682455(ELOVL6)

ORO:	101377904(ELOVL6)

EJU:	114222664(ELOVL6)

ZCA:	113918343 113925010(ELOVL6)

MLX:	118027093(ELOVL6)

NSU:	110575539(ELOVL6)

LWW:	102743226(ELOVL6)

FCA:	101082563(ELOVL6)

PYU:	121031001(ELOVL6)

PBG:	122477436(ELOVL6)

LRUF:

124520474

PTG:	102959362(ELOVL6)

PPAD:

109248175(ELOVL6)

AJU:	106983659(ELOVL6)

HHV:	120236156(ELOVL6)

BTA:	533333(ELOVL6)

BOM:	102285624(ELOVL6)

BIU:	109560249(ELOVL6)

BBUB:

102415342(ELOVL6)

BBIS:

105002072(ELOVL6)

CHX:	102181762(ELOVL6)

OAS:	101118274(ELOVL6)

ODA:	120861721(ELOVL6)

CCAD:

122422063(ELOVL6)

SSC:	100312970(ELOVL6)

CFR:	102522838(ELOVL6)

CBAI:

105067961(ELOVL6)

CDK:	105089906(ELOVL6)

VPC:	102536373(ELOVL6)

BACU:

103006337(ELOVL6)

LVE:	103073053(ELOVL6)

OOR:	101282143(ELOVL6)

DLE:	111186163(ELOVL6)

PCAD:

102976400(ELOVL6)

PSIU:

116754336(ELOVL6)

ECB:	100072829(ELOVL6)

EPZ:	103564006(ELOVL6)

EAI:	106829791(ELOVL6)

MYB:	102250132(ELOVL6)

MYD:	102758316(ELOVL6)

MMYO:

118672957(ELOVL6)

MLF:	102423146(ELOVL6)

MNA:	107534376(ELOVL6)

PKL:	118702707(ELOVL6)

HAI:	109379485(ELOVL6)

DRO:	112296252(ELOVL6)

SHON:

118977157(ELOVL6)

AJM:	119057455(ELOVL6)

PDIC:

114492814(ELOVL6)

PHAS:

123806833(ELOVL6)

MMF:	118639755(ELOVL6)

RFQ:	117021995(ELOVL6)

PALE:

102883753(ELOVL6)

PGIG:

120591195(ELOVL6)

PVP:	105292992(ELOVL6)

RAY:	107508817(ELOVL6)

MJV:	108407032(ELOVL6)

TOD:	119243626(ELOVL6)

SARA:

101542056(ELOVL6)

LAV:	100661059(ELOVL6)

TMU:

101348774

ETF:	101648153(ELOVL6)

DNM:	101416262(ELOVL6)

MDO:	100020799(ELOVL6)

GAS:	123238677 123252256(ELOVL6) 123255909

SHR:	100932904(ELOVL6)

PCW:	110218621(ELOVL6)

OAA:	100682198(ELOVL6)

GGA:	428772(ELOVL6) 770955(ELOVL3)

PCOC:

116231266(ELOVL6) 116234491(ELOVL3)

MGP:	100539665(ELOVL3) 100542840(ELOVL6)

CJO:	107313601(ELOVL6) 107315876(ELOVL3)

NMEL:

110397832(ELOVL6) 110400096(ELOVL3)

APLA:

101796167(ELOVL6) 101800182

ACYG:

106029862(ELOVL3) 106038658(ELOVL6)

AFUL:

116489082(ELOVL6) 116491427(ELOVL3)

TGU:	100231220(ELOVL6)

LSR:	110467993(ELOVL6)

SCAN:

103814198(ELOVL3) 103825997(ELOVL6)

PMOA:

120502100(ELOVL3) 120502780(ELOVL6)

OTC:	121331395(ELOVL6) 121341917(ELOVL3)

PRUF:

121350343(ELOVL3) 121360313(ELOVL6)

GFR:	102034097(ELOVL6) 102036402

FAB:	101815075(ELOVL3) 101819474(ELOVL6)

PHI:	102109718 102111803(ELOVL6)

PMAJ:

107203438(ELOVL6) 107206636(ELOVL3)

CCAE:

111927783(ELOVL6) 111930907

CCW:	104697131(ELOVL6) 104697939

CBRC:

103617335(ELOVL6) 103624583

ETL:	114054680(ELOVL3) 114062169(ELOVL6)

ZAB:	102066462(ELOVL3) 102074944(ELOVL6)

ACHL:

103797311(ELOVL6) 103809872

FPG:	101916709(ELOVL6)

FCH:	102049091(ELOVL6)

CLV:	102083706(ELOVL6)

EGZ:	104135536(ELOVL6)

NNI:	104021156(ELOVL6)

PLET:

104617513(ELOVL6)

PCRI:

104026441(ELOVL6)

PCAO:

104052682

ACUN:

113479671(ELOVL6) 113481649

TALA:

104358334(ELOVL6)

PADL:

103915603(ELOVL3) 103926096(ELOVL6)

AFOR:

103894291(ELOVL6) 103897814(ELOVL3)

ACHC:

115342135(ELOVL6) 115348331(ELOVL3)

HALD:

104310524 104321637(ELOVL6)

HLE:	104831977 104843354(ELOVL6)

AGEN:

126042855 126044914

GCL:

127015735

CCRI:

104161085 104161822(ELOVL6)

CSTI:

104553456 104555768(ELOVL6)

EHS:

104516803

CMAC:

104484076(ELOVL6)

MUI:	104538738(ELOVL6)

FGA:	104069455 104074141(ELOVL6)

GSTE:

104254788(ELOVL6)

LDI:	104345082(ELOVL6) 104351755

MNB:	103772712(ELOVL6)

OHA:	104327253(ELOVL6)

NNT:	104408904(ELOVL6)

DPUB:

104304148(ELOVL6)

PGUU:

104471929(ELOVL6)

ACAR:

104532080(ELOVL6)

CPEA:

104391503 104394502(ELOVL6)

AVIT:

104267408 104278526(ELOVL6)

CVF:	104286837(ELOVL6)

CUCA:

104062855(ELOVL6)

TEO:	104370874 104372978

BRHI:

104499299(ELOVL6)

AAM:	106492101(ELOVL6) 106498893

AROW:

112967503(ELOVL3) 112972470(ELOVL6)

NPD:	112956904(ELOVL3) 112957252(ELOVL6)

TGT:	104573057 104580797

DNE:	112980202(ELOVL3) 112984116(ELOVL6)

SCAM:

104138018(ELOVL6) 104141809

ASN:	102374102(ELOVL3) 102388851(ELOVL6)

AMJ:	102560004(ELOVL6) 102561888(ELOVL3)

CPOO:

109309385(ELOVL6)

GGN:	109301076(ELOVL6)

PSS:	102452886(ELOVL6) 102455762 112544680

CMY:	102933307(ELOVL6) 102943907(ELOVL3)

CPIC:

101935789(ELOVL6) 103306322(ELOVL3)

TST:	117878251(ELOVL6) 117880559(ELOVL3)

CABI:

116823595(ELOVL3) 116827247(ELOVL6)

MRV:	120369238(ELOVL3) 120407037(ELOVL6)

ACS:	100555143(elovl6)

PVT:	110087290(ELOVL6)

SUND:

121931954(ELOVL6)

PBI:	103061749(ELOVL6)

PMUR:

107290129(ELOVL6)

CTIG:

120305919(ELOVL6)

TSR:	106555129(ELOVL6)

PGUT:

117679943(ELOVL6)

VKO:	123022545(ELOVL6)

PMUA:

114603744(ELOVL6)

ZVI:	118083433(ELOVL6)

GJA:	107122700(ELOVL6)

STOW:

125439708(ELOVL6)

XLA:	108696247(elovl3.L) 108697499 108706706 108710167

XTR:	100497108(elovl3) 550011(elovl6)

NPR:	108785501 108798148(ELOVL6)

RTEM:

120917753(ELOVL6) 120947223(ELOVL3)

BBUF:

120989920(ELOVL6) 121005646(ELOVL3)

BGAR:

122919372(ELOVL6) 122941729(ELOVL3)

DRE:	100150288(elovl6l) 317738(elovl6)

SRX:	107713892 107716364 107723810 107740116 107743581

SANH:

107659697 107662963 107666569 107669077 107696872

SGH:	107555311 107565931 107569830(elovl6) 107595159

CCAR:

109057385 109058975 109065952 109076131 109088274(elovl6)

CAUA:

113057295 113057776 113079024 113099548 113111444 113113882

PPRM:

120474332(elovl6) 120480051(elovl6l)

MAMB:

125259130(elovl6) 125276806(elovl6l)

IPU:	100528278(elovl6) 108274257(zgc:92749)

PHYP:

113527066 113547206(elovl6)

SMEO:

124386291(elovl6) 124389095(zgc:92749)

TFD:	113648182(elovl6) 113652078(zgc:92749)

AMEX:

103026880 103036861(elovl6)

EEE:	113579946(elovl6) 113581569

TRU:	101061056(elovl6) 101064278 101069419

TNG:	GSTEN00022286G001 GSTEN00024401G001 GSTEN00025003G001

LCO:	104917910(elovl6) 104935483 104937337

NCC:	104953724(elovl6) 104962450 104964850

CGOB:

115014311(elovl6) 115025054

ELY:	117246816 117248348 117261506(elovl6)

EFO:	125880397 125894047(elovl6) 125903039

PLEP:

121948071(elovl6) 121954812 121958933

SLUC:

116052829 116052911(elovl6) 116060944

ECRA:

117937093 117940374 117951709(elovl6)

ESP:	116671203 116696527(elovl6)

PFLV:

114548221 114562761(elovl6)

GAT:	120817804(elovl6) 120819601 120820878

PPUG:

119211117(elovl6) 119213066 119213739

MSAM:

119888557(elovl6) 119911390(elovl6l) 119915861

CUD:	121510934(elovl6l) 121516715(elovl6) 121528468

ALAT:

119008111(elovl6) 119009821 119033492(elovl6l)

MZE:	101468487 101486796(elovl6) 101487029

ONL:	100697613 100706271(elovl6) 100711966

OAU:	116312806(elovl6l) 116321250 116335175(elovl6)

OLA:	101166505 101172187 101173129(elovl6)

OML:	112141464(elovl6) 112154472 112161373

XMA:	102219639(elovl6) 102221879 102231386

XCO:	114138059 114139428(elovl6) 114151949

XHE:	116712953 116714466(elovl6) 116727013

PRET:

103471827(elovl6) 103477396 103481830

PFOR:

103137347(elovl6) 103150640 103155333(elovl3)

PLAI:

106935888(elovl3) 106951750 106961686(elovl6)

PMEI:

106903852(elovl3) 106911525 106922413

GAF:	122823771 122837118(elovl6) 122842817

CVG:	107086525(elovl3) 107090217 107095818(elovl6)

CTUL:

119772611(elovl6) 119775993 119798746

GMU:	124858706 124860921(elovl6) 124875783

NFU:	107376140 107379691(elovl6) 107387310

KMR:	108236629(elovl6) 108246245 108251040

ALIM:

106513244(elovl6) 106536378 106536687

NWH:	119408617(elovl6) 119413607 119423847

AOCE:

111579360 111581330 111588379(elovl6)

MCEP:

125008211(elovl6) 125018513 125022644

CSEM:

103387155 103387156 103390643(elovl6) 103398846

POV:	109625467(elovl6) 109645847 109647966

SSEN:

122759585 122778695(elovl6) 122781844(elovl6l)

HHIP:

117753181 117769541(elovl6) 117775759 117775799

HSP:	118100857 118112538(elovl6) 118119515

LCF:	108873843 108885175 108891816 108892047

SDU:	111220434 111224204 111232488(elovl6)

SLAL:

111648282(elovl6) 111655441 111656751

XGL:	120785086(elovl6) 120794024 120796879

HCQ:	109524466(elovl6)

BPEC:

110153723(elovl6) 110154239

MALB:

109962779 109964301(elovl6) 109972984

BSPL:

114842000 114846530 114864028(elovl6)

SASA:

106579283 106589262 106604515 106606039 106611586(elovl6)

STRU:

115153120 115158957 115170825 115201013 115205116

OTW:	112221044(elovl6) 112223624 112224126 112253633(elovl6l) 112256329

OMY:	110488923(elovl6) 110492847 110499154 110502376 110505116

OGO:	123993498(elovl6) 124011121 124018025 124038194(elovl6l) 124048293

ONE:	115106502 115113292 115129546 115130803 115143918

SALP:

111965827 111967575 111967643 111978399 111978517 112080799

SNH:	120030030 120045612 120046220 120048038(elovl6) 120062248

CCLU:

121534531 121541539(elovl6) 121542418 121547252 121553420 121582837

ELS:	105006891 105010699 105027549

SFM:	108934869 108938677(elovl6)

PKI:	111839699 111848471 111849398(elovl6)

AANG:

118218182 118218184 118226747

LOC:	102689523(elovl6) 102690536

PSPA:

121295617 121321918 121322460 121325713

ARUT:

117409496 117415005 117417739 117421317 117964170

PSEX:

120533100(elovl6) 120538974(elovl6l)

LCM:	102348556(ELOVL6) 102351492(ELOVL3)

CMK:	103180891 103182716

RTP:	109921086 109929563

BFO:	118406088 118411420 118418599 118420714 118422001 118431853

BBEL:

109461896 109481369 109486408

CIN:	100182900 100184118

SCLV:

120347210

SPU:	100893456 589463 591559

APLC:

110990276

AJC:	117101639 117110039 117118967 117122440

SKO:	100367727 100372396 100372544 100374419 100375348 100375448 100375500 100375598 102807262

DME:	Dmel_CG3971(Baldspot)

DER:

6543939

DSE:

6605991

DSI:	Dsimw501_GD12451(Dsim_GD12451)

DYA:	Dyak_GE22199

DAN:

DSR:

DPO:

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI16709

DAZ:

DNV:

DHE:

DVI:

CCAT:

BOD:

RZE:	108377086 108380314

MDE:

SCAC:

LCQ:

LSQ:

HIS:

AGA:	AgaP_AGAP006520

ACOZ:

AARA:

ASTE:

AAG:

AALB:

109403124 109404336 115270339

CQU:	CpipJ_CPIJ003007

CPII:

120424487

CNS:

116342855

BCOO:

119077987 119077991 119079500

AME:	113219003 113219005 725031 725842

ACER:

107995792 107995803 108001947

ALAB:

122714444 122714544

BIM:	100741857 100743038 100745475 100746103 100748215 100748265 100748381 100749115 100749122

BBIF:

117208422 117208431 117208462 117212922 117212949 117213016 117213893 117215934 117216915 117217017 117217033 117217034 117217082

BVK:	117233705 117235981 117236462 117236463 117236501 117238848 117238912 117239420 117240630 117240943 117241058 117241294 117242223 117242679

BTER:

100643669 100645016 100645642 100646637 100647204 100648002 100649395 100649601 100649787

BPYO:

122571310 122571706 122574027 122576174 122576219 122576281 122576462 122576465 122576466 122577054

CCAL:

OBB:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

DQU:

CFO:

FEX:

LHU:

PGC:

OBO:

PCF:

PFUC:

VPS:

MDL:

CGLO:

FAS:

DAM:

AGIF:

CINS:

LHT:

CCIN:

TCA:

DPA:

SOY:

ATD:

CSET:

123311388 123311755 123312037 123312447 123312448

AGB:

LDC:

NVL:

APLN:

PPYR:

OTU:

BMOR:

BMAN:

MSEX:

DPL:	KGM_210062

BANY:

NIQ:

PMAC:

PPOT:

PXU:

PRAP:

PBX:

PNAP:

ZCE:

CCRC:

HAW:

HZE:

TNL:

SLIU:

OFU:

PXY:

CFEL:

API:	100169450(Elovl6)

DNX:

AGS:

RMD:

BTAB:

DCI:

CLEC:

HHAL:

NLU:

PHU:	Phum_PHUM601890

FOC:

TPAL:

ZNE:

CSEC:

SGRE:

DPX:	DAPPUDRAFT_309034

DMK:

116932723

DPZ:	124342043 124350642

PVM:	113816418 113816547

PJA:

PCHN:

HAME:

PCLA:

PTRU:

HAZT:

EAF:

LSM:

PPOI:

119091809 119094774 119104219

ISC:	IscW_ISCW022216

DSV:

RSAN:

RMP:

VDE:

VJA:

TUT:	107362910 107365107 107365938 107368612 107371763

DPTE:

113788432 113788434 113788448 113788449 113789170 113791112 113791115 113791116 113793021 113797054 113797230

DFR:	124490728 124493705 124494093 124495415 124497168 124497169 124497171 124497172 124497713 124500483

PTEP:

107453182

SDM:

118185556

CEL:	CELE_C40H1.4(elo-4) CELE_D2024.3(elo-3) CELE_F11E6.5(elo-2) CELE_F41H10.7(elo-5) CELE_F41H10.8(elo-6) CELE_F56H11.4(elo-1) CELE_Y53F4B.2(elo-9)

CBR:	CBG_00438(Cbr-elo-2) CBG_05815(Cbr-elo-3) CBG_10118(Cbr-elo-4) CBG_19953(Cbr-elo-6) CBG_19955(Cbr-elo-5) CBG_20021(Cbr-elo-1) CBG_20897(Cbr-elo-9)

BMY:	BM_BM3039(Bma-elo-3) BM_BM4008(Bma-elo-5) BM_BM4009(Bma-elo-6) BM_BM6605(Bma-elo-2.2) BM_BM6752(Bma-elo-9) BM_BM9655(Bma-elo-1)

LOA:	LOAG_05719 LOAG_07896 LOAG_11536 LOAG_11651 LOAG_12530 LOAG_15715 LOAG_16825

NAI:	NECAME_04021 NECAME_06398 NECAME_07611 NECAME_07915 NECAME_09057 NECAME_09531 NECAME_15365 NECAME_17211 NECAME_17319

TSP:	Tsp_02709 Tsp_06132

HRO:	HELRODRAFT_190584 HELRODRAFT_78878

LGI:	LOTGIDRAFT_155331 LOTGIDRAFT_184049 LOTGIDRAFT_184058 LOTGIDRAFT_210968 LOTGIDRAFT_210971

PCAN:

BGT:

GAE:

HRF:

HRJ:

CRG:

MYI:

PMAX:

MMER:

123545352 123545353 123545354 123545355 123563955 123564867

OBI:

106883414

OSN:

115214027

LAK:	106150704 106158004

TAD:	TRIADDRAFT_24364 TRIADDRAFT_55215

AQU:	100631646 100631897 100633678

SRE:	PTSG_05210

ACAN:

ACA1_128530 ACA1_207820 ACA1_307890

PYO:	PY17X_0205700

PCB:	PCHAS_0202700

PKN:	PKNH_0204500

PVX:	PVX_081320

PCY:	PCYB_021500

CPV:

cgd8_4630

CHO:	Chro.80534

TGO:	TGME49_205350

SMIN:

v1.2.033476.t1(symbB.v1.2.033476.t1)

FCY:	FRACYDRAFT_268497

NGD:	NGA_0640610 NGA_0640620 NGA_0726800

AAF:	AURANDRAFT_13493 AURANDRAFT_31406

PIF:	PITG_01411

PSOJ:

PHYSODRAFT_544717

SPAR:

SPRG_07927 SPRG_07928 SPRG_13938 SPRG_17697

EHX:	EMIHUDRAFT_237636 EMIHUDRAFT_43654(ELO_b) EMIHUDRAFT_43684 EMIHUDRAFT_66051 EMIHUDRAFT_70214(ELO_a)

GTT:	GUITHDRAFT_102853

TBR:	Tb927.7.4180

TBG:	TbgDal_VII4670 TbgDal_VII4680 TbgDal_VII4690

TCR:

506661.30

LMA:	LMJF_14_0640(ELO1.1) LMJF_14_0660(ELO1.3)

LIF:	LINJ_14_0660 LINJ_14_0680 LINJ_14_0700 LINJ_14_0710 LINJ_14_0720 LINJ_14_0730 LINJ_14_0740 LINJ_14_0760 LINJ_14_0800

LDO:	LDBPK_140660 LDBPK_140680 LDBPK_140700 LDBPK_140710 LDBPK_140730 LDBPK_140740 LDBPK_140760 LDBPK_140800

LMI:	LMXM_14_0640 LMXM_14_0660 LMXM_14_0680 LMXM_14_0690 LMXM_14_0740 LmxM_14_0730a_1

LBZ:	LBRM_14_0630 LBRM_14_0650 LBRM_14_0670 LBRM_14_0690 LBRM_14_0720

LPAN:

LPMP_140640 LPMP_140660 LPMP_140680 LPMP_140700 LPMP_140730

NGR:	NAEGRDRAFT_29306

» show all

Reference

PMID:11567032

Authors

Moon YA, Shah NA, Mohapatra S, Warrington JA, Horton JD

Title

Identification of a mammalian long chain fatty acyl elongase regulated by sterol regulatory element-binding proteins.

Journal

J Biol Chem 276:45358-66 (2001)
DOI:10.1074/jbc.M108413200

Sequence

[mmu:170439]

Reference

PMID:16564093

Authors

Jakobsson A, Westerberg R, Jacobsson A.

Title

Fatty acid elongases in mammals: their regulation and roles in metabolism.

Journal

Prog Lipid Res 45:237-49 (2006)
DOI:10.1016/j.plipres.2006.01.004

LinkDB

ORTHOLOGY: K10250

Entry

K10250                      KO

Symbol

ELOVL7

Name

elongation of very long chain fatty acids protein 7 [EC:2.3.1.199]

Pathway

map00062

Fatty acid elongation

map01040

Biosynthesis of unsaturated fatty acids

map01100

Metabolic pathways

map01110

Biosynthesis of secondary metabolites

map01212

Fatty acid metabolism

Module

M00415

Fatty acid elongation in endoplasmic reticulum

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09103 Lipid metabolism
   00062 Fatty acid elongation
    K10250  ELOVL7; elongation of very long chain fatty acids protein 7
   01040 Biosynthesis of unsaturated fatty acids
    K10250  ELOVL7; elongation of very long chain fatty acids protein 7
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01004 Lipid biosynthesis proteins
    K10250  ELOVL7; elongation of very long chain fatty acids protein 7
Enzymes [BR:ko01000]
2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.199  very-long-chain 3-oxoacyl-CoA synthase
     K10250  ELOVL7; elongation of very long chain fatty acids protein 7
Lipid biosynthesis proteins [BR:ko01004]
Elongase
  PUFA
   K10250  ELOVL7; elongation of very long chain fatty acids protein 7

Other DBs

RN:	R09419 R10825

GO:

0009922

Genes

HSA:	79993(ELOVL7)

PTR:	736134(ELOVL7)

PPS:	100973834(ELOVL7)

GGO:	101154080(ELOVL7)

PON:	100460606(ELOVL7)

NLE:	100591430(ELOVL7)

MCC:	709866(ELOVL7)

MCF:	102142519(ELOVL7)

MTHB:

126956993

CSAB:

103222048(ELOVL7)

CATY:

105572017(ELOVL7)

PANU:

101010834(ELOVL7)

TGE:	112626871(ELOVL7)

RRO:	104681641(ELOVL7)

RBB:	108515483(ELOVL7)

TFN:	117065166(ELOVL7)

PTEH:

111541608(ELOVL7)

CANG:

105519026(ELOVL7)

CJC:	100392386(ELOVL7)

SBQ:	101048081(ELOVL7)

CSYR:

103264417(ELOVL7)

MMUR:

105877264(ELOVL7)

LCAT:

123648252(ELOVL7)

PCOQ:

105826565(ELOVL7)

OGA:	100953092(ELOVL7)

MMU:	74559(Elovl7)

MCAL:

110308022(Elovl7)

MPAH:

110329039(Elovl7)

RNO:	361895(Elovl7)

MCOC:

116083429(Elovl7)

MUN:	110546135(Elovl7)

CGE:	100754940(Elovl7)

MAUA:

101825797(Elovl7)

PLEU:

114703478(Elovl7)

MORG:

121455928(Elovl7)

MFOT:

126512571

AAMP:

119809735(Elovl7)

NGI:	103724484(Elovl7)

HGL:	101725989(Elovl7)

CPOC:

100735649(Elovl7)

CCAN:

109702323(Elovl7)

DORD:

105992395(Elovl7)

DSP:	122117198(Elovl7)

NCAR:

124987413

OCU:

100352767

OPI:	101527888(ELOVL7)

TUP:	102490443(ELOVL7)

GVR:	103602280(ELOVL7)

CFA:	608997(ELOVL7)

CLUD:

112659898(ELOVL7)

VVP:	112935342(ELOVL7)

VLG:	121497215(ELOVL7)

AML:	100472747(ELOVL7)

UMR:	103663654(ELOVL7)

UAH:	113255309(ELOVL7)

UAR:	123790170(ELOVL7)

ELK:

111156963

LLV:

125100858

MPUF:

101681386(ELOVL7)

ORO:	101386520(ELOVL7)

EJU:	114221006(ELOVL7)

ZCA:	113929056(ELOVL7)

MLX:	118016816(ELOVL7)

NSU:	110590981(ELOVL7)

LWW:	102749705(ELOVL7)

FCA:	101098770(ELOVL7)

PYU:	121015528(ELOVL7)

PBG:	122489276(ELOVL7)

LRUF:

124517478

PTG:	102963086(ELOVL7)

PPAD:

109246364(ELOVL7)

AJU:	106976394(ELOVL7)

HHV:	120239510(ELOVL7)

BTA:	614096(ELOVL7)

BOM:	102264723(ELOVL7)

BIU:	109575017(ELOVL7)

BBUB:

102398097(ELOVL7)

BBIS:

104998360(ELOVL7)

CHX:	102182633(ELOVL7)

OAS:	101108515(ELOVL7)

ODA:	120879549(ELOVL7)

CCAD:

122454498(ELOVL7)

SSC:	100524592(ELOVL7)

CFR:	102519498(ELOVL7)

CBAI:

105077785(ELOVL7)

CDK:	105084728(ELOVL7)

VPC:	102534172(ELOVL7)

BACU:

103001100(ELOVL7)

LVE:	103079296(ELOVL7)

OOR:	101272522(ELOVL7)

DLE:	111186409(ELOVL7)

PCAD:

102974433(ELOVL7)

PSIU:

116751760(ELOVL7)

ECB:	100051272(ELOVL7)

EPZ:	103542331(ELOVL7)

EAI:	106824625(ELOVL7)

MYB:	102251752(ELOVL7)

MYD:	102763394(ELOVL7)

MMYO:

118655825(ELOVL7)

MLF:	102442914(ELOVL7)

MNA:	107526319(ELOVL7)

PKL:	118703074(ELOVL7)

HAI:	109392870(ELOVL7)

DRO:	112321022(ELOVL7)

SHON:

118998625(ELOVL7)

AJM:	119046953(ELOVL7) 119046956

PDIC:

114498386(ELOVL7)

PHAS:

123824716(ELOVL7)

MMF:	118641973(ELOVL7)

RFQ:	117025282(ELOVL7)

PALE:

102878282(ELOVL7)

PGIG:

120608207(ELOVL7)

PVP:	105311165(ELOVL7)

RAY:	107506375(ELOVL7)

MJV:	108402547(ELOVL7)

TOD:	119260479(ELOVL7)

SARA:

101556618(ELOVL7)

LAV:	100657711(ELOVL7)

TMU:

101356459

ETF:	101639529(ELOVL7)

DNM:	101438997(ELOVL7)

MDO:	100032201(ELOVL7)

GAS:	123231466(ELOVL7)

SHR:	100916522(ELOVL7)

PCW:	110222337(ELOVL7)

OAA:	100089956(ELOVL7)

GGA:	431579(ELOVL7)

PCOC:

116236678(ELOVL7)

MGP:	104914910(ELOVL7)

CJO:	107306023(ELOVL7)

NMEL:

110389646(ELOVL7)

APLA:

101795175(ELOVL7)

ACYG:

106035664(ELOVL7)

AFUL:

116500565(ELOVL7)

TGU:	100227813(ELOVL7)

LSR:	110472621(ELOVL7)

SCAN:

103821040(ELOVL7)

PMOA:

120502506(ELOVL7)

OTC:	121341249(ELOVL7)

PRUF:

121355374(ELOVL7)

GFR:	102043526(ELOVL7)

FAB:	101810772(ELOVL7)

PHI:	102109506(ELOVL7)

PMAJ:

107198273(ELOVL7)

CCAE:

111941531(ELOVL7)

CCW:	104686686(ELOVL7)

CBRC:

103623757(ELOVL7)

ETL:	114057209(ELOVL7)

ZAB:	102067026(ELOVL7)

ACHL:

103807537(ELOVL7)

FPG:	101920661(ELOVL7)

FCH:	102059496(ELOVL7)

CLV:	102096235(ELOVL7)

EGZ:	104128372(ELOVL7)

NNI:	104021078(ELOVL7) 104022974

PLET:

104622816(ELOVL7)

PCRI:

104025190(ELOVL7)

PCAO:

104049241(ELOVL7)

ACUN:

113489903(ELOVL7)

TALA:

104357178(ELOVL7)

PADL:

103918748(ELOVL7)

AFOR:

103893391(ELOVL7)

ACHC:

115337321(ELOVL7) 121232878

HALD:

104321829(ELOVL7)

HLE:	104839935(ELOVL7)

AGEN:

126035368 126036070

GCL:

127027515

CCRI:

104154881(ELOVL7)

CSTI:

104555285(ELOVL7)

EHS:	104508230(ELOVL7)

CMAC:

104473318(ELOVL7)

FGA:	104070587(ELOVL7)

GSTE:

104251614(ELOVL7)

LDI:

104341041

MNB:	103776866(ELOVL7)

OHA:	104337717(ELOVL7)

NNT:	104411001(ELOVL7)

DPUB:

104308840(ELOVL7)

PGUU:

104463356(ELOVL7)

ACAR:

104526831(ELOVL7)

CPEA:

104395635(ELOVL7)

AVIT:

104276694(ELOVL7)

CVF:	104294647(ELOVL7)

CUCA:

104058113(ELOVL7)

TEO:	104376272(ELOVL7)

BRHI:

104499196(ELOVL7)

AAM:

106496820

AROW:

112971780(ELOVL7)

NPD:	112946021(ELOVL7)

TGT:	104577360(ELOVL7)

DNE:	112995784(ELOVL7)

SCAM:

104146867(ELOVL7)

ASN:	102387008(ELOVL7)

AMJ:	102574009(ELOVL7)

CPOO:

109307943(ELOVL7)

GGN:	109297792(ELOVL7)

PSS:	102451620(ELOVL7)

CMY:	102936627(ELOVL7)

CPIC:

101939673(ELOVL7)

TST:	117879319(ELOVL7)

CABI:

116837049(ELOVL7)

MRV:	120408079(ELOVL7)

ACS:	100552766(elovl7)

PVT:	110073969(ELOVL7)

SUND:

121922599(ELOVL7)

PBI:	103054730(ELOVL7)

PMUR:

107295765(ELOVL7)

CTIG:

120297500(ELOVL7)

TSR:	106539164(ELOVL7)

PGUT:

117679216(ELOVL7)

VKO:	123031622(ELOVL7)

PMUA:

114606530(ELOVL7)

ZVI:	118077129(ELOVL7)

GJA:	107111936(ELOVL7)

STOW:

125436035(ELOVL7)

XLA:	398440(elovl7.L) 432300(elovl7.S)

XTR:	448054(elovl7)

NPR:	108788207(ELOVL7)

RTEM:

120928696(ELOVL7)

BBUF:

120991343(ELOVL7)

BGAR:

122936291(ELOVL7)

DRE:	327274(elovl7b) 334217(elovl7a)

SRX:	107706775 107709106 107743866 107752445

SANH:

107654403 107657867 107699661 107704168

SGH:	107548300(elovl7) 107588931 107599803 107602232

CCAR:

109079531 109086663 109107243

CAUA:

113054720 113069850 113107077 113110194

PPRM:

120481966(elovl7a) 120482176 120483080

MAMB:

125262532(elovl7b) 125279426(elovl7a)

IPU:	108265965(elovl7a) 108277391(elovl7b)

PHYP:

113535127(elovl7) 113544705

SMEO:

124393982(elovl7b) 124400418(elovl7a)

TFD:	113634291(elovl7a) 113638455(elovl7b)

AMEX:

103029677(elovl7) 103047077

EEE:	113580051(elovl7) 113584099

TRU:	101064204(elovl7)

LCO:	104922955(elovl7)

NCC:	104942897(elovl7)

CGOB:

115013293(elovl7)

ELY:	117252821(elovl7a)

EFO:	125891017(elovl7a)

PLEP:

121944357(elovl7a)

SLUC:

116056762(elovl7a)

ECRA:

117945172(elovl7a)

ESP:	116689599(elovl7)

PFLV:

114555959(elovl7)

GAT:	120830338(elovl7a)

PPUG:

119224680(elovl7a)

MSAM:

119892291(elovl7a)

CUD:	121510313(elovl7a)

ALAT:

119020172(elovl7a)

MZE:	101473791(elovl7)

ONL:	100699387(elovl7)

OAU:	116311153(elovl7a)

OLA:	101167544(elovl7)

OML:	112148827(elovl7a)

XMA:	102228254(elovl7)

XCO:	114154210(elovl7)

XHE:	116729309(elovl7)

PRET:

103470169(elovl7)

PFOR:

103135436(elovl7)

PLAI:

106956044(elovl7)

PMEI:

106916962(elovl7)

GAF:	122828780(elovl7a)

CVG:	107098476(elovl7)

CTUL:

119781102(elovl7a)

GMU:	124878476(elovl7a)

NFU:	107394079(elovl7)

KMR:	108244810(elovl7a)

ALIM:

106513731(elovl7)

NWH:	119413306(elovl7a)

AOCE:

111588628(elovl7)

MCEP:

125012652(elovl7a)

CSEM:

103397061 103398294(elovl7)

POV:	109639320(elovl7)

SSEN:

122770181(elovl7a)

HHIP:

117767982(elovl7a)

HSP:	118114627(elovl7a)

LCF:	108878163(elovl7a)

SDU:	111230827(elovl7)

SLAL:

111645118(elovl7)

XGL:	120805651(elovl7a)

HCQ:	109520685(elovl7)

BPEC:

110167017(elovl7)

MALB:

109956680(elovl7)

BSPL:

114861973(elovl7a)

SASA:

106571348 106580590 106585161

STRU:

115160071 115164229 115200413

OTW:	112246743 112248776 112262635

OMY:	110523186 110525928 110536303

OGO:	123989479 124034115 124036528

ONE:	115111834 115118405 115140285

SALP:

111958179 111961929 111974972

SNH:	120025950 120055457 120063378

CCLU:

121581856 121583181(elovl7b) 121584219

ELS:	105014118(elovl7) 105021735

SFM:	108938672(elovl7)

PKI:	111839309(elovl7)

AANG:

118206408(elovl7a) 118212091

LOC:	102691065(elovl7)

PSPA:

121300814 121316835

ARUT:

117400099 117403542

PSEX:

120532590(elovl7a)

LCM:	102349419(ELOVL7)

CMK:	103177806(elovl7a)

RTP:	109911928(elovl7)

CIN:

SCLV:

SPU:

APLC:

AJC:

SKO:

DER:	6552256 6552257 6552259 6553574 6554897 6555116 6555117 6555119

DSI:	Dsimw501_GD18447(Dsim_GD18447) Dsimw501_GD18449(Dsim_GD18449) Dsimw501_GD18652(Dsim_GD18652) Dsimw501_GD18654(Dsim_GD18654) Dsimw501_GD19443(Dsim_GD19443) Dsimw501_GD19676(Dsim_GD19676) Dsimw501_GD20751(Dsim_GD20751) Dsimw501_GD20962(Dsim_GD20962) Dsimw501_GD20987(Dsim_GD20987)

DYA:	Dyak_GE10310 Dyak_GE10338 Dyak_GE11104 Dyak_GE24026 Dyak_GE24028 Dyak_GE24722 Dyak_GE24723 Dyak_GE25348 Dyak_GE25754 Dyak_GE25995

DSR:	110177352 110184290 110188262 110188395 110188529 110188627 110188643 110190470

DPO:	4800612 4800613 4800614 4801489 4802014

DPE:	6588232 6588280 6594866 6594869 6594870

DMN:	108154354 108155517 108156264 108157235 108157463 108157570 108157695

DWI:	111519023 26529704 6638227 6648185 6650098 6650604 6651039 6651041 6651462

DMO:	Dmoj_GI10223 Dmoj_GI22067 Dmoj_GI22068 Dmoj_GI22725 Dmoj_GI23310 Dmoj_GI24279 Dmoj_GI26751

DAZ:	108608758 108608768 108608943 108608944 108609025 108616687 108616705 108616715

DNV:	108657725 108659395 108659656 108659657 108659659 108660347 115562179 115563514

DHE:	111602732 111604961 111604962 111605432 111605434 111605454 111605475 111605491 111605494

DVI:

6631212

MDE:	101889280 101889844 101893043 101895939 101896282 101896454 101897989 101898711 101901541

LCQ:	111676445 111676459 111678937 111687204 111687205 111688494 111690486

HIS:

119654929

AGA:	AgaP_AGAP001097 AgaP_AGAP003195 AgaP_AGAP003600 AgaP_AGAP004372 AgaP_AGAP005511 AgaP_AGAP008780 AgaP_AGAP011812 AgaP_AGAP011848

ACOZ:

120948435 120950627 120951871 120951872 120953516 120957083 120957793

AARA:

120894833 120896640 120897673 120901624 120903089

AAG:	5563869 5568917 5569887 5570005 5572161 5575560 5575620 5576405 5578161

CQU:	CpipJ_CPIJ000109 CpipJ_CPIJ001449 CpipJ_CPIJ003687 CpipJ_CPIJ013663 CpipJ_CPIJ013818 CpipJ_CPIJ014005 CpipJ_CPIJ015710 CpipJ_CPIJ016815 CpipJ_CPIJ019159

CPII:

120412768 120418800 120420316 120420428 120421294 120423379 120429045 120429624 120429627 120430351

AME:	409638 413789 550828 551938 724552 724867

ACER:

107995511 108000351 108000352 108000397

ALAB:

122711763 122711767 122714601

BIM:	100742309 100743508 100744329 100746186 100748887 100749526 100749961

BBIF:

117208215 117208259 117208286 117214169

BVK:	117232640 117236052 117238562 117238564

BVAN:

117156971 117159203 117159204 117159228

BTER:

100642650 100642769 100644219 100645831 100648720 100651171 100652206 105666309

BPYO:

122567418 122573526 122573535 122573537

CCAL:

108627086 108627088 108627142 108627146 108631348 108631352 113463877 113463878

OBB:	114878686 114878690 114878692 114878693 114878694 114878695 114878714 114882857

MGEN:

117220438 117220490

NMEA:

116424576 116424691

CGIG:

122395826 122395846 122395914 122404183

SOC:	105196722 105201316 105205086 105205458 105205885 105207261 105207270 105207307 113004660

MPHA:

105829383 105829984 105829985 105829986 105833908 105834487 105837346 105837347 105839441

AEC:	105144501 105146021 105146624 105146627 105146630 105147399 105151913 105153687 105154038

ACEP:

105622161 105622162 105622164 105622168 105622218 105622219 105623563

PBAR:

105431030 105431148 105431149 105431151 105431156 105431158 105431741

VEM:	105560798 105561806 105561807 105561811 105567408 105567410 105567411

HST:	105180979 105182046 105182047 105185296 105190303 105190304 105191177 105191178 105191324 112589499 112590546 112590547 112590548

DQU:	106744319 106744687 106746443 106746446 106746447 106746448 106746988 106749824 106751438

CFO:	105252028 105255192 105257385 105258625 105258626 105258629 105258633 105258634

FEX:	115234417 115244356 115245256 115245307 115245473

LHU:	105668738 105671264 105671787 105671789 105671794 105671796 105671809 105671813 105671814 105671838 105671853 105677475

PGC:	109855314 109856612 109856614 109856616 109856617 109857837 109858185 109859752 109861511 109861512 109861630 109861631 109863095

OBO:	105274817 105274818 105285818 105285819 105285823

PCF:	106792382 106792384 106792389

PFUC:

122518741 122518804

VPS:	122638215 122638217 122638218

NVI:	100115035 100115103 100115131 100115199 100115239 100115278

CSOL:

105360297 105360298 105360299 105360304 105360305 105360306 105360452 105361963

TPRE:

106658566 106659351

MDL:	103575955 103575960 103575961 103580573 103580590 103580633

CGLO:

123261696

DAM:

107039045

AGIF:

122855855 122858710

LHT:	122508541 122508542

CCIN:

107273830 107273834 107273856

TCA:	103312111 103315088 655474 655561 656977 657055 657137 657220 660197 660257

DPA:	109542083 109543928 109545546 109545595 109546290 109546885

SOY:

115886128

ATD:	109598764 109598768 109598772 109598775 109598777 109598780 109601396 109601397 109605049 109607682

AGB:	108908003 108913580

LDC:

111507302

NVL:	108557522 108563111 108563112 108563113 108566760

PPYR:

116160044

BMOR:

101735510 101735595 101737339 101737481 101737765 101737905 101740518 101740658 101741086 105841346

BMAN:

114240115 114240116 114240118 114240148 114240189 114241019 114241022 114247746

MSEX:

115441072 115441100 115448225 115453539 115453591 115453592 119188364 119190761

DPL:	KGM_202897 KGM_209920 KGM_209933 KGM_209934 KGM_211375 KGM_211377 KGM_215874 KGM_215875 KGM_215920

BANY:

112043722 112043723 112044101 112044103 112045745 112045748 112051308

NIQ:	126768534 126768536 126768542 126768550 126768762 126768831

PMAC:

106709857 106709860 106709915 106716754 106716773 106716791

PPOT:

106100114 106100119 106100137 106100233 106101692 106102416

PXU:	106125140 106125389 106125468 106125536 106125577 106125580

PRAP:

110994720 110996832 110996940 110998396 110998397

PBX:	123707961 123708257 123711917 123711918 123712444 123712581

ZCE:	119831045 119831123 119831245 119831308 119831363 119831364 119831426 119831681

CCRC:

123692321 123692371 123692429 123692576 123692640 123692691 123698943

HAW:	110370437 110370451 110370452 110370453 110370478 110370481 110370488 110370512 110375258 110375259 110375261

HZE:	124630309 124630334 124630394 124630441 124630454 124630459 124630584 124630587 124630711

TNL:	113495025 113495276 113495283 113495284 113495285 113495287 113495288 113495289 113495290 113495291 113496901 113502299 113502411 113505359 113506546

SLIU:

111349276 111349309 111349324 111349489 111349501 111349549 111349677

OFU:	114354367 114354374 114354382 114357673 114359439 114360565

PXY:	105382558 105382566 105382588 105382815 105382831 105383338 105390965 105392381 105392404 105394874 105394883

API:	100161792 100162176 100163976 100164244 100166007

DNX:	107163743 107164274 107165252 107169921

AGS:	114120749 114120762 114124683 114129690

RMD:	113550915 113551165 113551401 113554217 113557001

BTAB:

109030474 109033208 109033624 109033843 109037959 109038525 109044510

CLEC:

106664652 106665457 106665458 106667328 106667329 106670822 106673267 106673598

HHAL:

106679816 106681060

NLU:	111043687 111044447 111045617 111048769 111049563 111054749 111056394 111058755 111061949 120353832

PHU:	Phum_PHUM047320 Phum_PHUM047430 Phum_PHUM381320 Phum_PHUM381330 Phum_PHUM381440 Phum_PHUM576950

FOC:

113207067

TPAL:

117647801

ZNE:	110829941 110829959 110829969 110829970 110836531 110840095 110840431 110840434

CSEC:

111865041 111870250 111870259 111872368

FCD:

110859935

DPX:	DAPPUDRAFT_322487 DAPPUDRAFT_41014 DAPPUDRAFT_41788

DMK:	116916398 116916400 116917582

DPZ:	124341245 124341250 124341253 124341256 124341259

PVM:

113818785

EAF:

111695059

ISC:	IscW_ISCW002250 IscW_ISCW002738 IscW_ISCW015223 IscW_ISCW015224 IscW_ISCW015226 IscW_ISCW017055

RMP:	119169358 119169366 119169369 119169539 119169864 119170322 119170352 119170397 119170851 119170861 119173644 119174140 119174444

VDE:	111249292 111253140 111255006

VJA:	111263401 111266212 111271266

TUT:	107359998 107362953 107365149 107365666

DPTE:

113791931 113793004 113798158

DFR:	124497423 124497718

PTEP:

107439040 107441671 107454137 110282901 122271648

SDM:	118186805 118188084 118195850 118200938

HRO:	HELRODRAFT_76239

LGI:	LOTGIDRAFT_165788 LOTGIDRAFT_186121 LOTGIDRAFT_85833

PCAN:

BGT:

GAE:

HRF:

HRJ:

CRG:

MYI:	110456741 110463293

PMAX:

117323957 117325969

MMER:

123525221 123545406

OBI:	106871442 106871573

OSN:	115213789 115218688

LAK:

106175006

SMM:	Smp_010770.1 Smp_130370

SHX:	MS3_00009485(ELOVL7_4)

OVI:	T265_16087

EGL:

EGR_06613

EHX:	EMIHUDRAFT_433098 EMIHUDRAFT_434059 EMIHUDRAFT_443249

» show all

Reference

PMID:19826053

Authors

Tamura K, Makino A, Hullin-Matsuda F, Kobayashi T, Furihata M, Chung S, Ashida S, Miki T, Fujioka T, Shuin T, Nakamura Y, Nakagawa H

Title

Novel lipogenic enzyme ELOVL7 is involved in prostate cancer growth through saturated long-chain fatty acid metabolism.

Journal

Cancer Res 69:8133-40 (2009)
DOI:10.1158/0008-5472.CAN-09-0775

Sequence

[hsa:79993]

Reference

PMID:20937905

Authors

Ohno Y, Suto S, Yamanaka M, Mizutani Y, Mitsutake S, Igarashi Y, Sassa T, Kihara A

Title

ELOVL1 production of C24 acyl-CoAs is linked to C24 sphingolipid synthesis.

Journal

Proc Natl Acad Sci U S A 107:18439-44 (2010)
DOI:10.1073/pnas.1005572107

LinkDB

ORTHOLOGY: K10245

Entry

K10245                      KO

Symbol

ELO2

Name

fatty acid elongase 2 [EC:2.3.1.199]

Pathway

map00062

Fatty acid elongation

map01040

Biosynthesis of unsaturated fatty acids

map01100

Metabolic pathways

map01110

Biosynthesis of secondary metabolites

map01212

Fatty acid metabolism

Module

M00415

Fatty acid elongation in endoplasmic reticulum

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09103 Lipid metabolism
   00062 Fatty acid elongation
    K10245  ELO2; fatty acid elongase 2
   01040 Biosynthesis of unsaturated fatty acids
    K10245  ELO2; fatty acid elongase 2
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01004 Lipid biosynthesis proteins
    K10245  ELO2; fatty acid elongase 2
Enzymes [BR:ko01000]
2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.199  very-long-chain 3-oxoacyl-CoA synthase
     K10245  ELO2; fatty acid elongase 2
Lipid biosynthesis proteins [BR:ko01004]
Elongase
  LCFA
   K10245  ELO2; fatty acid elongase 2

Other DBs

RN:	R07758 R07762 R09419 R10825

GO:

0009922

Genes

SCE:	YCR034W(ELO2) YJL196C(ELO1)

SEUB:

DI49_0786 DI49_2836

SPAO:

SPAR_C00890 SPAR_J00240

AGO:	AGOS_AFR624W

ERC:

Ecym_8137

KLA:	KLLA0_C03542g

KMX:	KLMA_10159(FEN1)

LTH:	KLTH0F03740g

VPO:	Kpol_2001p51

ZRO:	ZYRO0C17842g

CGR:	CAGL0L08184g

NCS:	NCAS_0B08500(NCAS0B08500)

NDI:	NDAI_0A00730(NDAI0A00730)

TPF:	TPHA_0A02570(TPHA0A02570)

TBL:	TBLA_0J01230(TBLA0J01230)

TGB:	HG536_0B01580

TDL:	TDEL_0C05610(TDEL0C05610)

KAF:	KAFR_0G00240(KAFR0G00240)

KNG:	KNAG_0C00860(KNAG0C00860)

ZMK:	HG535_0A01530

PPA:	PAS_chr3_0602

DHA:	DEHA2G10054g

PIC:	PICST_34675(ELO2)

PGU:	PGUG_02768

SPAA:

SPAPADRAFT_61610

LEL:	LELG_03574

CAL:	CAALFM_C112790CA(FEN1) CAALFM_C203230CA(FEN12)

CTP:	CTRG_01179 CTRG_03563

COT:	CORT_0D01380

CDU:	CD36_11970 CD36_17980

CTEN:

CANTEDRAFT_109600

YLI:	YALI0B20196g

CLU:	CLUG_04704

CLUS:

A9F13_11g00913

CAUR:

CJI97_004080

PKZ:	C5L36_0B09610

BNN:	FOA43_000668(ELO2)

BBRX:

BRETT_003288(ELO2)

OPA:	HPODL_01167

SLUD:

SCDLUD_004033

SSL:	SS1G_01397

CPW:	CPC735_029650

URE:	UREG_03944

SPO:	SPAC1639.01c

» show all

Reference

PMID:8702485

Authors

Toke DA, Martin CE

Title

Isolation and characterization of a gene affecting fatty acid elongation in Saccharomyces cerevisiae.

Journal

J Biol Chem 271:18413-22 (1996)
DOI:10.1074/jbc.271.31.18413

Reference

PMID:9211877

Authors

Oh CS, Toke DA, Mandala S, Martin CE

Title

ELO2 and ELO3, homologues of the Saccharomyces cerevisiae ELO1 gene, function in fatty acid elongation and are required for sphingolipid formation.

Journal

J Biol Chem 272:17376-84 (1997)
DOI:10.1074/jbc.272.28.17376

LinkDB

ORTHOLOGY: K10246

Entry

K10246                      KO

Symbol

ELO3

Name

fatty acid elongase 3 [EC:2.3.1.199]

Pathway

map00062

Fatty acid elongation

map01040

Biosynthesis of unsaturated fatty acids

map01100

Metabolic pathways

map01110

Biosynthesis of secondary metabolites

map01212

Fatty acid metabolism

Module

M00415

Fatty acid elongation in endoplasmic reticulum

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09103 Lipid metabolism
   00062 Fatty acid elongation
    K10246  ELO3; fatty acid elongase 3
   01040 Biosynthesis of unsaturated fatty acids
    K10246  ELO3; fatty acid elongase 3
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01004 Lipid biosynthesis proteins
    K10246  ELO3; fatty acid elongase 3
Enzymes [BR:ko01000]
2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.199  very-long-chain 3-oxoacyl-CoA synthase
     K10246  ELO3; fatty acid elongase 3
Lipid biosynthesis proteins [BR:ko01004]
Elongase
  LCFA
   K10246  ELO3; fatty acid elongase 3

Other DBs

RN:	R07758 R07762 R09419 R10825

GO:

0009922

Genes

AJM:

119040513

QSU:	111983754 112000897

CME:	CYME_CML178C

GSL:	Gasu_34740

CCP:	CHC_T00009084001

SCE:	YLR372W(ELO3)

SEUB:

DI49_3872

SPAO:

SPAR_L03830

AGO:	AGOS_AFR586W

ERC:

Ecym_2766

KLA:	KLLA0_B07777g

KMX:	KLMA_50271(SUR4)

LTH:	KLTH0D13596g

VPO:	Kpol_472p4

ZRO:	ZYRO0B07458g

CGR:	CAGL0G04851g

NCS:	NCAS_0A02340(NCAS0A02340) NCAS_0J01280(NCAS0J01280)

NDI:	NDAI_0D04530(NDAI0D04530) NDAI_0J02040(NDAI0J02040)

TPF:	TPHA_0B02400(TPHA0B02400)

TBL:	TBLA_0I02760(TBLA0I02760)

TGB:	HG536_0E01390

TDL:	TDEL_0E01530(TDEL0E01530)

KAF:	KAFR_0A06140(KAFR0A06140) KAFR_0G00130(KAFR0G00130)

KNG:	KNAG_0B05920(KNAG0B05920) KNAG_0D04240(KNAG0D04240)

ZMK:	HG535_0F01680

PPA:	PAS_chr3_0236

DHA:	DEHA2G05478g

PIC:	PICST_20287

PGU:	PGUG_02923

SPAA:

SPAPADRAFT_60817

LEL:	LELG_01308

COT:	CORT_0A11090

CTEN:

CANTEDRAFT_114306

CLU:	CLUG_01575

CLUS:

A9F13_13g00165

CAUR:

CJI97_000512

PKZ:	C5L36_0D06190

BNN:	FOA43_004431(ELO3)

BBRX:

BRETT_002242(ELO3)

OPA:	HPODL_03697

SLUD:

SCDLUD_004221

NCR:

NCU06694

NTE:	NEUTE1DRAFT75853(NEUTE1DRAFT_75853)

SMP:	SMAC_06641

PAN:	PODANSg9011

TTT:	THITE_69856

MTM:	MYCTH_79157

CTHR:

CTHT_0028400

MGR:

MGG_07280

PPEI:

PpBr36_01921

TMN:	UCRPA7_3775 UCRPA7_4209 UCRPA7_5833

SSCK:

SPSK_05380

FGR:	FGSG_07347

FPU:	FPSE_04157

FVR:	FVEG_07913

FOX:	FOXG_01555

NHE:	NECHADRAFT_101623

TRE:	TRIREDRAFT_119931 TRIREDRAFT_75116

TRR:	M419DRAFT_138217 M419DRAFT_95085

MAW:

MAC_05925

MAJ:

MAA_07869

CMT:

CCM_03752

PLJ:	VFPFJ_07953

VAL:	VDBG_04167

VDA:	VDAG_01393

CFJ:	CFIO01_09535 CFIO01_09942

CLUP:

CLUP02_07800 CLUP02_14048

CHIG:

CH63R_04116 CH63R_06044

SAPO:

SAPIO_CDS8936

ELA:	UCREL1_4634 UCREL1_9701

PFY:	PFICI_10902

SSL:	SS1G_13908

BFU:	BCIN_15g04790

MBE:

MBM_08440

PSCO:

LY89DRAFT_687597 LY89DRAFT_706944

GLZ:	GLAREA_03309 GLAREA_11697

ANI:	AN6435.2 AN8117.2

AFM:	AFUA_5G02760

ACT:	ACLA_002400

NFI:	NFIA_039340

AOR:	AO090003000572 AO090102000393

ANG:	ANI_1_1400024(An02g09910)

AFV:	AFLA_001119 AFLA_011840

ALUC:

AKAW2_10842A

ACHE:

ACHE_50974A

APUU:

APUU_51493A APUU_60904A

PCS:	Pc21g18830

PDP:	PDIP_51140

TMF:	PMAA_015850 PMAA_080890

TRG:	TRUGW13939_10209 TRUGW13939_10810

CIM:	CIMG_06474

PBL:	PAAG_07247

PBN:	PADG_05751

ABE:

ARB_06714

TVE:

TRV_04055

AJE:	HCAG_00436

PTE:

PTT_07837

BZE:	COCCADRAFT_23380

BSC:	COCSADRAFT_188084

BOR:	COCMIDRAFT_103481

AALT:

CC77DRAFT_1059342

ZTR:	MYCGRDRAFT_101073

PFJ:	MYCFIDRAFT_46549

FFU:	CLAFUR5_07554

BCOM:

BAUCODRAFT_214158

NPA:	UCRNP2_7018 UCRNP2_8526

TML:	GSTUM_00003835001

SPO:	SPAC1B2.03c

TVS:	TRAVEDRAFT_159174

PCO:	PHACADRAFT_180203

FME:	FOMMEDRAFT_167250

GTR:	GLOTRDRAFT_109058

PGR:	PGTG_05274

MLR:	MELLADRAFT_42723

MBR:	MONBRDRAFT_33213

DPP:	DICPUDRAFT_159984

GTT:	GUITHDRAFT_66090

» show all

Reference

PMID:9211877

Authors

Oh CS, Toke DA, Mandala S, Martin CE

Title

ELO2 and ELO3, homologues of the Saccharomyces cerevisiae ELO1 gene, function in fatty acid elongation and are required for sphingolipid formation.

Journal

J Biol Chem 272:17376-84 (1997)
DOI:10.1074/jbc.272.28.17376

LinkDB

DBGET integrated database retrieval system