KEGG ORTHOLOGY: K15401

ORTHOLOGY: K15401

Entry

K15401                      KO

Symbol

CYP86A1

Name

long-chain fatty acid omega-monooxygenase [EC:1.14.14.80]

Pathway

map00071

Fatty acid degradation

map00073

Cutin, suberine and wax biosynthesis

Reaction

R01348

fatty acid,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (omega-hydroxylating)

R09452

(9Z)-octadecenoic acid,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (omega-hydroxylating)

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09103 Lipid metabolism
   00071 Fatty acid degradation
    K15401  CYP86A1; long-chain fatty acid omega-monooxygenase
   00073 Cutin, suberine and wax biosynthesis
    K15401  CYP86A1; long-chain fatty acid omega-monooxygenase
09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450
    K15401  CYP86A1; long-chain fatty acid omega-monooxygenase
Enzymes [BR:ko01000]
1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.80  long-chain fatty acid omega-monooxygenase
     K15401  CYP86A1; long-chain fatty acid omega-monooxygenase
Cytochrome P450 [BR:ko00199]
Cytochrome P450, plant type
  CYP86 family
   K15401  CYP86A1; long-chain fatty acid omega-monooxygenase

Genes

ATH:	AT5G58860(CYP86A1)

ALY:	9298712 9319613

CRB:

17876473

CSAT:

104726463 104736111 104761986

EUS:	EUTSA_v10013214mg

BRP:	103851611 103856662

BNA:	106387137 106417417 106436003 106446557

BOE:	106325857 106332387

RSZ:

108843879

THJ:	104799404 104814908

CPAP:

110810038

CIT:

102613603

CIC:	CICLE_v10030097mg

PVY:	116129478 116141261

MINC:

123209005 123225380

TCC:

18590528

GRA:	105761893 105765892 105788721

GHI:	107886047 107906610 107928745 107954198 107959180 107960045

GAB:	108482488 108485983 108488867

DZI:	111302131 111304340

EGR:	104422403 104432660

GMX:	100787559 100788343

GSJ:	114374509 114383137

PVU:	PHAVU_006G065000g PHAVU_008G262600g

VRA:	106764310 106775311

VAR:	108342444 108345240

VUN:	114186806 114193475

CCAJ:

109795231 109806524

APRC:

113851192 113874411

MTR:	11410613 25490822

TPRA:

123881785 123918067

CAM:	101488875 101497352

PSAT:

127084606 127121252

LJA:	Lj0g3v0102229.1(Lj0g3v0102229.1) Lj0g3v0132879.1(Lj0g3v0132879.1)

ADU:	107458375 107493120

AIP:	107608237 107609505

AHF:	112702875 112720024 112766291 112792057

LANG:

PCIN:

FVE:

RCN:

PPER:

PMUM:

PAVI:

PDUL:

MDM:	103418919 103422686

MSYL:

PXB:

ZJU:

MNT:

CSAV:

CSV:

CMO:

BHJ:

CMAX:

CMOS:

CPEP:

RCU:

JCU:

HBR:	110640242 110666355

MESC:

110603116 110616950

POP:	7468004 7481488

PEU:	105131069 105133070

PALZ:

JRE:

CILL:

CAVE:

QSU:

QLO:

TWL:	119990944 120001842

VVI:

VRI:

SLY:

SPEN:

SOT:	102577568 102578777

SSTN:

125868927 125875213

CANN:

107848605 107852712 107874613

LBB:	132606058 132606066

NTA:	107762865 107793147

NSY:

NTO:

NAU:

INI:

ITR:

SIND:

OEU:	111369696 111389639

EGT:

SSPL:

SMIL:

APAN:

HAN:	110878899 110940131

ECAD:

LSV:

CCAV:

DCR:

CSIN:

RVL:	131314339 131317082

AEW:	130770277 130795211

BVG:

104899987

SOE:

110803013

CQI:	110683428 110688292

ATRI:

MOF:

NNU:

MING:

TSS:	122649873 122658389

PSOM:

113310106 113320826

OSA:

4324825

DOSA:

Os01t0854800-01(Os01g0854800)

OBR:

OGL:

BDI:

ATS:

TDC:	119269623 119277639

TAES:

123062632 123071452 123079793

TUA:

LPER:

LRD:

SBI:

ZMA:	100192044 100273463

SITA:

SVS:

PVIR:

PHAI:

PDA:

EGU:	105046261 105048564

MUS:

103990198

ZOF:	122002518 122006772

DCT:

110104795

PEQ:

110022081

AOF:	109829536 109849308

ATR:

18437877

» show all

Reference

PMID:18544608

Authors

Hofer R, Briesen I, Beck M, Pinot F, Schreiber L, Franke R

Title

The Arabidopsis cytochrome P450 CYP86A1 encodes a fatty acid omega-hydroxylase involved in suberin monomer biosynthesis.

Journal

J Exp Bot 59:2347-60 (2008)
DOI:10.1093/jxb/ern101

Sequence

[ath:AT5G58860]

Reference

PMID:9500987

Authors

Benveniste I, Tijet N, Adas F, Philipps G, Salaun JP, Durst F

Title

CYP86A1 from Arabidopsis thaliana encodes a cytochrome P450-dependent fatty acid omega-hydroxylase.

Journal

Biochem Biophys Res Commun 243:688-93 (1998)
DOI:10.1006/bbrc.1998.8156

Sequence

[ath:AT5G58860]

LinkDB

ORTHOLOGY: K15398

Entry

K15398                      KO

Symbol

CYP86A4S

Name

fatty acid omega-hydroxylase [EC:1.14.-.-]

Pathway

map00073

Cutin, suberine and wax biosynthesis

map01100

Metabolic pathways

Reaction

R09451

hexadecanoic acid:fatty acid omega-hydroxylase

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09103 Lipid metabolism
   00073 Cutin, suberine and wax biosynthesis
    K15398  CYP86A4S; fatty acid omega-hydroxylase
09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450
    K15398  CYP86A4S; fatty acid omega-hydroxylase
Cytochrome P450 [BR:ko00199]
Cytochrome P450, plant type
  CYP86 family
   K15398  CYP86A4S; fatty acid omega-hydroxylase

Genes

ATH:	AT1G01600(CYP86A4) AT1G63710(CYP86A7) AT2G45970(CYP86A8) AT4G00360(CYP86A2)

ALY:	9309026 9316278 9324007 9325426

CRB:	17883908 17889267 17894125 17897912

CSAT:

104703994 104705301 104711889 104714724 104753040 104783172 104784721 104793567

EUS:	EUTSA_v10001389mg EUTSA_v10007350mg EUTSA_v10023410mg EUTSA_v10028550mg

BRP:	103836926 103843799 103844662 103853312 103866938

BNA:	106370867 106395007 106426066 106434156 106434946 106435771 106453391 111204414 111213676 125586307 125593491

BOE:	106295656 106311525 106318020 106327264 106341840

RSZ:	108807252 108808993 108827722 108861437

THJ:	104801403 104809382 104817295 104825844

CPAP:

110806488 110820909

CIT:	102627840 102631431 127901167

CIC:	CICLE_v10019616mg CICLE_v10019633mg

PVY:	116134090 116134295

MINC:

123212174 123215756 123223153

TCC:	18606545 18614125

GRA:	105765232 105791610 105792235 105802706

GHI:	107887453 107900880 107912593 107922796 107931941 107941510 107947035

GAB:	108468191 108471061 108473626 108474794

DZI:	111278197 111305938 111313313 111315595

EGR:	104441741 104442113

GMX:	100779012 100779986 100792719

GSJ:	114405733 114413388 114418427 114421025

PVU:	PHAVU_002G290700g PHAVU_010G099900g

VRA:	106769560 106774045

VAR:	108321196 108347015

VUN:	114166755 114176918

CCAJ:

109799840 109802444

APRC:

113849994 113854210

MTR:	11444029 25502058

TPRA:

123884228 123915937

CAM:	101495684 101504119

PSAT:

127075966 127105554

LJA:	Lj2g3v0345070.1(Lj2g3v0345070.1) Lj3g3v2341010.1(Lj3g3v2341010.1) Lj4g3v2963520.1(Lj4g3v2963520.1)

ADU:	107472463 107479928

AIP:	107621470 107630780

AHF:	112726277 112730504 112732703 112790882

LANG:

109333174 109337524 109339922 109349951

PCIN:

129284598 129287656 129291145

FVE:	101296893 101309153

RCN:	112179785 112181614

PPER:

PMUM:

PAVI:

PDUL:

MDM:	103401894 103404945 103437295 114821007

MSYL:

126599364 126623707 126626485 126628581

PXB:	103957382 103963865

ZJU:	107429862 107432980

MNT:	21395621 21407006

CSAV:

115706480

CSV:	101216733 101221526

CMO:	103482759 103497711

BHJ:	120068558 120092982

MCHA:

CMAX:

CMOS:

CPEP:

RCU:	8261894 8287395

JCU:	105642970 105645789

HBR:	110636275 110656077 110656092 110660089 110660632

MESC:

110614753 110616942

POP:	7458180 7496976

PEU:	105124365 105133991

PALZ:

118028456 118041636

JRE:	108997464 109014476 109021535

CILL:

122282807 122289550 122310155

CAVE:

132188754

QSU:	111988103 112024208

QLO:	115957909 115971615

TWL:	119986778 120004057

VVI:	100247907 100249915

VRI:	117906808 117931594

SLY:

SPEN:

SOT:

SSTN:

CANN:

LBB:

NTA:	107787094 107788811 107827543

NSY:

NTO:

NAU:

INI:

ITR:

SIND:

OEU:	111385507 111410339

EGT:

SSPL:

SMIL:

APAN:

HAN:	110864775 110920845 118479703

ECAD:

122594066 122611330

LSV:	111886517 111901125 111902672

CCAV:

112499610 112526439 112528313

DCR:	108196352 108209464 108215276

CSIN:

114257372 114283135

RVL:	131333385 131333825

AEW:	130765251 130780753 130780837 130793245

BVG:	104887268 104892281

SOE:	110784972 110789731

CQI:	110702412 110714053 110719538 110731547

ATRI:

130811327

MOF:	131164808 131166859

NNU:	104596033 104610622

MING:

122080934 122087345

TSS:	122646645 122648408 122655408 122664722

PSOM:

113274726 113304286

OSA:	4330250 4336648

DOSA:

Os02t0666500-01(Os02g0666500) Os04t0560100-01(Os04g0560100)

OBR:	102703653 102719856

OGL:	127761128 127769434

BDI:

100838392

ATS:	109740636 109741799

TDC:	119317331 119324038 119356090 119365233

TAES:

123046333 123054190 123127911 123137723 123145001 123190080

LPER:

127306749 127335967

LRD:	124671486 124679263 124686988 124688030

SBI:	8064644 8073927 8078691

ZMA:	100192011 100501810

SITA:

101757229 101786122

SVS:	117835569 117862540

PVIR:

120641415 120656741 120682543 120711965

PHAI:

112899298 112900288

PDA:	103717433 103717729

EGU:	105033928 105042911

MUS:	103982670 103984476 103985950

ZOF:	121989042 121992728 121996691 121997996 122020452 122025032 122042440 122046951 122052265 122056754

DCT:	110095646 110097389

PEQ:

AOF:

NCOL:

ATR:

Reference

PMID:19959665

Authors

Li-Beisson Y, Pollard M, Sauveplane V, Pinot F, Ohlrogge J, Beisson F

Title

Nanoridges that characterize the surface morphology of flowers require the synthesis of cutin polyester.

Journal

Proc Natl Acad Sci U S A 106:22008-13 (2009)
DOI:10.1073/pnas.0909090106

Sequence

[ath:AT1G01600]

LinkDB

ORTHOLOGY: K15402

Entry

K15402                      KO

Symbol

CYP86B1

Name

fatty acid omega-hydroxylase [EC:1.14.-.-]

Pathway

map00073

Cutin, suberine and wax biosynthesis

Reaction

R09454

docosanoate,NADPH:oxygen oxidoreductase (22-hydroxylating)

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09103 Lipid metabolism
   00073 Cutin, suberine and wax biosynthesis
    K15402  CYP86B1; fatty acid omega-hydroxylase
09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450
    K15402  CYP86B1; fatty acid omega-hydroxylase
Cytochrome P450 [BR:ko00199]
Cytochrome P450, plant type
  CYP86 family
   K15402  CYP86B1; fatty acid omega-hydroxylase

Genes

ATH:	AT5G08250 AT5G23190(CYP86B1)

ALY:	9308111 9309417

CRB:	17884197 17884623

CSAT:

104706620 104708272 104734843 104736333 104769028 104770669

EUS:	EUTSA_v10003923mg EUTSA_v10013132mg

BRP:	103854909 103860518

BNA:	106380104 106404620 106439893 111214227 125582020

BOE:	106304140 106324636

RSZ:	108809782 108851462

THJ:

104800878

CPAP:

110824345

CIT:

102607755

CIC:	CICLE_v10031117mg

PVY:

MINC:

TCC:

GRA:

GHI:	107894043 107898863 121215947

GAB:

108459753

DZI:	111294200 111308409

EGR:

104454009

GMX:	100787593 100791555 100809503

GSJ:	114366895 114374092 114402730

PVU:	PHAVU_011G029000g

VRA:

VAR:

VUN:

CCAJ:

APRC:

MTR:	11444405 25482827 25482828

TPRA:

123892523 123917752

CAM:

101498094

PSAT:

127106325

LJA:	Lj0g3v0071839.1(Lj0g3v0071839.1) Lj3g3v3513760.1(Lj3g3v3513760.1) Lj3g3v3523900.1(Lj3g3v3523900.1)

ADU:

107477198

AIP:

107628704

AHF:	112737105 112789198

LANG:

PCIN:

FVE:

RCN:

PPER:

PMUM:

PAVI:

PDUL:

MDM:	103403397 103451451 103451675

MSYL:

126597052 126606268 126610722

PXB:	103943216 103945558

ZJU:

107435098

MNT:

21401079

CSAV:

115708003

CSV:	101212202 101222831

CMO:	103499965 103500347

BHJ:	120086723 120089973

MCHA:

CMAX:

CMOS:

CPEP:

RCU:

JCU:

HBR:

MESC:

POP:	7457181 7486378

PEU:	105112691 105123947

PALZ:

JRE:

CILL:

CAVE:

QSU:	112009780 112034512

QLO:	115972448 115979405

TWL:

VVI:

VRI:

SLY:

SPEN:

SOT:

SSTN:

CANN:

LBB:

NTA:	107768511 107820146

NSY:

NTO:

NAU:

INI:

ITR:

SIND:

OEU:	111376535 111403013

EGT:	105959990 105967840

SSPL:

121767414 121770839

APAN:

127260471

HAN:	110894644 110897365

ECAD:

LSV:

CCAV:

DCR:

CSIN:

RVL:

AEW:

BVG:	104892372 104902574

SOE:	110784306 110784991

CQI:	110702083 110716276

ATRI:

130799230 130805037

MOF:

131153466

NNU:

104589018

MING:

122058317 122079048 122088835

TSS:	122646757 122665332

PSOM:

113293351 113306534

OSA:

4348947

DOSA:

Os10t0486100-00(Os10g0486100)

OBR:

102703152

OGL:

127786409

BDI:

100824104

ATS:	109751960 109758709

TDC:	119269719 119333690

TAES:

123046509 123122012 123167513 123181127

TUA:

125508769

LPER:

127301169

LRD:	124649942 124681412

SBI:

8067126

ZMA:	100217282 100501739

SITA:

SVS:

PVIR:

PHAI:

PDA:	103711958 103711959 103712453 103716599 120107103

EGU:	105032701 105032702 105053723 105053742

MUS:	103975801 103982415 103982732 103990236

ZOF:	121982949 121987525 121989021 121997958

DCT:	110099638 110109253

PEQ:	110019105 110033691

AOF:

109839587

NCOL:

116248369 116259718 116260378 116260594

ATR:

18437587

SMO:	SELMODRAFT_124000(CYP86F3) SELMODRAFT_128482

PPP:	112285118 112288238

PTRC:

PtA15_11A691 PtA15_11A694

» show all

Reference

PMID:19525321

Authors

Compagnon V, Diehl P, Benveniste I, Meyer D, Schaller H, Schreiber L, Franke R, Pinot F

Title

CYP86B1 is required for very long chain omega-hydroxyacid and alpha, omega -dicarboxylic acid synthesis in root and seed suberin polyester.

Journal

Plant Physiol 150:1831-43 (2009)
DOI:10.1104/pp.109.141408

Sequence

[ath:AT5G23190]

LinkDB

REACTION: R09451

Entry

R09451                      Reaction

Name

hexadecanoic acid:fatty acid omega-hydroxylase

Definition

Hexadecanoic acid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 16-Hydroxypalmitate + [Oxidized NADPH---hemoprotein reductase] + H2O

Equation

C00249 + C03024 + C00007 <=> C18218 + C03161 + C00001

Reaction class

RC00797

C00249_C18218

Enzyme

1.14.14.80 1.14.-.-

Pathway

rn00073

Cutin, suberine and wax biosynthesis

rn01100

Metabolic pathways

Brite

Enzymatic reactions [BR:br08201]
1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.80
     R09451  Hexadecanoic acid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 16-Hydroxypalmitate + [Oxidized NADPH---hemoprotein reductase] + H2O
   1.14.-  Acting on paired donors, with incorporation or reduction of molecular oxygen
    1.14.-.-
     R09451  Hexadecanoic acid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 16-Hydroxypalmitate + [Oxidized NADPH---hemoprotein reductase] + H2O
IUBMB reaction hierarchy [BR:br08202]
1. Oxidoreductase reactions
  1.14.14.80
   R12072  Long-chain fatty acid <=> omega-Hydroxy-long-chain fatty acid
    R09451  Hexadecanoic acid <=> 16-Hydroxypalmitate

Orthology

K15398

fatty acid omega-hydroxylase [EC:1.14.-.-]

K20495

long-chain fatty acid omega-monooxygenase [EC:1.14.14.80]

Other DBs

RHEA:

40202

LinkDB

REACTION: R09452

Entry

R09452                      Reaction

Name

(9Z)-octadecenoic acid,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (omega-hydroxylating)

Definition

(9Z)-Octadecenoic acid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 18-Hydroxyoleate + [Oxidized NADPH---hemoprotein reductase] + H2O

Equation

C00712 + C03024 + C00007 <=> C19616 + C03161 + C00001

Comment

fatty acid omega-hydroxylase

Reaction class

RC00797

C00712_C19616

Enzyme

1.14.14.80

Pathway

rn00073

Cutin, suberine and wax biosynthesis

Brite

Enzymatic reactions [BR:br08201]
1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.80
     R09452  (9Z)-Octadecenoic acid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 18-Hydroxyoleate + [Oxidized NADPH---hemoprotein reductase] + H2O
IUBMB reaction hierarchy [BR:br08202]
1. Oxidoreductase reactions
  1.14.14.80
   R12072  Long-chain fatty acid <=> omega-Hydroxy-long-chain fatty acid
    R09452  (9Z)-Octadecenoic acid <=> 18-Hydroxyoleate

Orthology

K15401

long-chain fatty acid omega-monooxygenase [EC:1.14.14.80]

K20495

long-chain fatty acid omega-monooxygenase [EC:1.14.14.80]

Other DBs

RHEA:

41731

LinkDB

REACTION: R09454

Entry

R09454                      Reaction

Name

docosanoate,NADPH:oxygen oxidoreductase (22-hydroxylating)

Definition

Docosanoic acid + NADPH + Oxygen + H+ <=> 22-Hydroxydocosanoate + NADP+ + H2O

Equation

C08281 + C00005 + C00007 + C00080 <=> C19623 + C00006 + C00001

Comment

fatty acid omega-hydroxylase

Reaction class

RC00001

C00005_C00006

RC00797

C08281_C19623

Enzyme

1.14.-.-

Pathway

rn00073

Cutin, suberine and wax biosynthesis

Brite

Enzymatic reactions [BR:br08201]
1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.-  Acting on paired donors, with incorporation or reduction of molecular oxygen
    1.14.-.-
     R09454  Docosanoic acid + NADPH + Oxygen + H+ <=> 22-Hydroxydocosanoate + NADP+ + H2O

Orthology

K15402

fatty acid omega-hydroxylase [EC:1.14.-.-]

LinkDB

DBGET integrated database retrieval system