KEGG   ORTHOLOGY: K15404
Entry
K15404                      KO                                     
Symbol
K15404, CER1
Name
aldehyde decarbonylase [EC:4.1.99.5]
Pathway
map00073  Cutin, suberine and wax biosynthesis
map01110  Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09103 Lipid metabolism
   00073 Cutin, suberine and wax biosynthesis
    K15404  K15404, CER1; aldehyde decarbonylase
Enzymes [BR:ko01000]
 4. Lyases
  4.1  Carbon-carbon lyases
   4.1.99  Other carbon-carbon lyases
    4.1.99.5  aldehyde oxygenase (deformylating)
     K15404  K15404, CER1; aldehyde decarbonylase
Other DBs
RN: R09466
GO: 0071771
Genes
ATH: AT1G02190 AT1G02205(CER1) AT2G37700
ALY: 9315772 9328081 9330760
CRB: 17890234 17899648 17900261 17900889
CSAT: 104700905 104758142 104759026 104770317 104773539 104773540 104773742 104773743 104773763 104773764 104782202 104785716 104787457 104788709 104792563 109124978
EUS: EUTSA_v10007056mg EUTSA_v10009534mg EUTSA_v10016375mg
BRP: 103843834 103857727 103865622 103865625 103867170
BNA: 106392348 106404754 106407983 106410643 106426031 106427726 106437024 106451050
BOE: 106308419 106329420 106329421 106337750 106339989 106342430
RSZ: 108810757 108830245 108834933 108837140 108844545 108845328 108856796
THJ: 104799403 104810724 104813547
PVY: 116135943
MINC: 123222816
LJA: Lj1g3v4156050.1(Lj1g3v4156050.1) Lj3g3v0618210.1(Lj3g3v0618210.1) Lj3g3v0618250.1(Lj3g3v0618250.1) Lj4g3v1120540.1(Lj4g3v1120540.1)
JCU: 105643380
DOSA: Os02t0621300-01(Os02g0621300) Os02t0814200-01(Os02g0814200) Os10t0471100-01(Os10g0471100)
DCT: 110112743
PEQ: 110021075
SMO: SELMODRAFT_129942(CER1-2) SELMODRAFT_230422(CER1-1)
PPP: 112278187
 » show all
Reference
PMID:8718622
  Authors
Aarts MG, Keijzer CJ, Stiekema WJ, Pereira A
  Title
Molecular characterization of the CER1 gene of arabidopsis involved in epicuticular wax biosynthesis and pollen fertility.
  Journal
Plant Cell 7:2115-27 (1995)
DOI:10.1105/tpc.7.12.2115
  Sequence
[ath:AT1G02205]
LinkDB

KEGG   ENZYME: 4.1.99.5
Entry
EC 4.1.99.5                 Enzyme                                 
Name
aldehyde oxygenase (deformylating);
decarbonylase;
aldehyde decarbonylase;
octadecanal decarbonylase;
octadecanal alkane-lyase
Class
Lyases;
Carbon-carbon lyases;
Other carbon-carbon lyases
Sysname
a long-chain aldehyde alkane-lyase
Reaction(IUBMB)
a long-chain aldehyde + O2 + 2 NADPH + 2 H+ = an alkane + formate + H2O + 2 NADP+ [RN:R03728]
Reaction(KEGG)
R03728;
(other) R09466
Substrate
long-chain aldehyde [CPD:C00609];
O2 [CPD:C00007];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Product
alkane [CPD:C01371];
formate [CPD:C00058];
H2O [CPD:C00001];
NADP+ [CPD:C00006]
Comment
Contains a diiron center. Involved in the biosynthesis of alkanes. The enzyme from the cyanobacterium Nostoc punctiforme PCC 73102 is only active in vitro in the presence of ferredoxin, ferredoxin reductase and NADPH, and produces mostly C15 and C17 alkanes [2,3]. The enzyme from pea (Pisum sativum) produces alkanes of chain length C18 to C32 and is inhibited by metal-chelating agents [1]. The substrate for this enzyme is formed by EC 1.2.1.80, acyl-[acyl-carrier protein] reductase.
History
EC 4.1.99.5 created 1989, modified 2011, modified 2013
Pathway
ec00073  Cutin, suberine and wax biosynthesis
ec01110  Biosynthesis of secondary metabolites
Orthology
K14331  fatty aldehyde decarbonylase
K15404  aldehyde decarbonylase
Genes
ATHAT1G02190 AT1G02205(CER1) AT2G37700
ALY9315772 9328081 9330760
CRB17890234 17899648 17900261 17900889
CSAT104700905 104758142 104759026 104770317 104773539 104773540 104773742 104773743 104773763 104773764 104782202 104785716 104787457 104788709 104792563 109124978
EUSEUTSA_v10007056mg EUTSA_v10009534mg EUTSA_v10016375mg
BRP103843834 103857727 103865622 103865625 103867170
BNA106392348 106404754 106407983 106410643 106426031 106427726 106437024 106451050
BOE106308419 106329420 106329421 106337750 106339989 106342430
RSZ108810757 108830245 108834933 108837140 108844545 108845328 108856796
THJ104799403 104810724 104813547
CPAP110807870 110816250
CIT102609996 102610181 102610308
CICCICLE_v10011291mg CICLE_v10019265mg CICLE_v10019279mg
PVY116135943
MINC123222816
TCC108660922 108663945 108663946 18585715 18590332 18607120 18607121 18607128
GRA105773703 105774362 105779994 105779995 105792677
GHI107900564 107948639 107960346 107961728 107962103 107962105 107962106 121218563
GAB108457980 108470923 108484138 108485455 108485729
DZI111282051 111282066 111282088 111293740 111302090 111303798 111309702
EGR104430284 104431049 104441318 104441320 104441328 104442842 104442848 104442849
GMX100790115 100805835 100818557
GSJ114406437 114406438 114406439 114418764 114418835
PVUPHAVU_010G040500g PHAVU_010G040600g
VRA106772969 106772995 106773669
VAR108347155 108347177 108347190
VUN114166431 114166486 114167540
CCAJ109790836 109792954 109814131 109817909 109817915
APRC113850617 113863345
MTRMTR_4g054150 MTR_4g054290 MTR_7g090100 MTR_7g090120 MTR_7g090140 MTR_8g009560 MTR_8g009590
CAM101508006 101514081 101514846
LJALj1g3v4156050.1(Lj1g3v4156050.1) Lj3g3v0618210.1(Lj3g3v0618210.1) Lj3g3v0618250.1(Lj3g3v0618250.1) Lj4g3v1120540.1(Lj4g3v1120540.1)
ADU107472613 107472630 107494920
AIP107605303 107610850 107618742
AHF112697362 112701648 112730784 112730831 112769914 112776197 112779428
LANG109352187 109361171 109363612
FVE101297683 101308477 101311999 101312286
RCN112181465 112182338 112186659 112187442 112188030 112193250 112195581
PPER18785414 18786441 18787082 18787499 18787644
PMUM103331413 103331414 103331441 103331464 103344052
PAVI110757365 110771793 110771794
PDUL117617785 117617786
MDM103406883 103428452 103433190
PXB103929751 103929753 103929757 103932050 103965505 103965506
ZJU107403677 107403679 107403682 107403845 107421712 107421713
MNT21406637 21406640
CSV101203441 101203691 101221193 101222843
CMO103483417 103483418 103483426 103498990
BHJ120067038 120068459 120072793
MCHA111016028 111016029 111016030 111022778
CMAX111473822 111473823 111479677 111494235
CMOS111431767 111443967 111443973 111464399
CPEP111778304 111785111 111789761 111799545 111799672
RCU8266676 8266677
JCU105643380
HBR110638963 110641046 110649196
MESC110614572 110614939 110614983 110615004 110616986
POP18105327 18105329 18105332 7463394
PEU105111451 105116944
PALZ118040415 118045229
JRE108989715 109008029 109008030
QSU111998302 111998303 111998304 111999683 112009915 112018104 112030629
QLO115968885 115968966 115986553 115987043 115987049
TWL119982248 119982311 119982317 119983062
VVI100243849 100250668 100252221 100256874 100261967 100262701 100854413
VRI117909465 117931548 117931596 117931863 117931870 117931966 117932772
SLY101252060 101263099 101267647 101267934 101268663
SPEN107005221 107005457 107008221 107008222 107014415 107014566 107025013
SOT102579007 102579333 102579884 102593084 102595750 102599091 102599945
CANN107844046 107844196 107844359 107851087 107851578 107854358 107868261
NTA107759567 107773304 107774629 107778616 107785373 107800178 107801545 107809310 107817101 107821267 107823602
NSY104212478 104227074 104228614 104235229 104240300 104244089
NTO104084728 104084731 104096116 104106154 104107044 104116100
NAU109209082 109209347 109214395 109222351 109223843 109234408 109234411 109244845
INI109182241 109182254 109182262
ITR116014996 116015011 116017410 116027583
SIND105167221 105167251 105173435 105173436
OEU111373242 111373243 111376458 111377333 111410890 111411605
EGT105952439 105954794 105954795
SSPL121752170 121773259 121774062 121775596 121775769 121777449 121792609 121802233 121804405 121807145
HAN110897451 110897561 110912685 110920509
ECAD122590796 122595065
LSV111878549 111905990
CCAV112522670 112526942
DCR108193604 108193835 108200521 108202980 108216902
CSIN114261760 114261768 114301969
BVG104905209 104905211
SOE110778839 110792520
CQI110688922 110720448 110720450 110720452 110721591 110721593 110721594 110739445
NNU104590840 104596252 104596253 104596254 104611270 104611276
MING122077770 122079509 122079802 122079803
TSS122654307 122658652 122658661 122658674 122658681
PSOM113275162 113280221 113285408 113290441 113296001 113304842 113326033 113326085 113336172 113339276 113340194 113349541 113350373 113350987 113352694 113357337
NCOL116266056 116266181
OSA4330012 4331117 4336381
DOSAOs02t0621300-01(Os02g0621300) Os02t0814200-01(Os02g0814200) Os10t0471100-01(Os10g0471100)
OBR102703957 102714431 102717322 102718869
BDI100825208 100833295 100833807 100833914 100837949
ATS109733084 109747194 109756465 109759643 109759677 109765469 109765470 109774093
TDC119268601 119268609 119317146 119318483 119320989 119321025 119321193 119324367 119331085 119355884 119355886 119365025
TAES100125734 100192181 123045141 123045147 123046137 123054020 123083993 123120828 123120849 123127749 123128943 123139672 123146104 123152997 123169144 123181004 123181005 123186892 123189906 123189907
SBI8064469 8067437 8072487 8084204 8084699
ZMA100273712 100280261 100382841
SITA101762753 101769789 101772770 101775794
SVS117841046 117848300 117863027 117863265
PVIR120646073 120650814 120656480 120682920 120690773 120709010
PHAI112874964 112875267 112882648 112899988
PDA103699030 103711898 113463032
EGU105044200 105044255 105055747
MUS103971700 103992720
DCT110112743
PEQ110021075
AOF109824901 109825477 109832741 109836409 109845087 109849475 109851020
ATR18447308 18447310 18447313
SMOSELMODRAFT_129942(CER1-2) SELMODRAFT_230422(CER1-1)
PPP112278187
PPJRK21_05027
PBCCD58_03975
SYNsll0208
SYZMYO_122780
SYYSYNGTS_2252(sll0208)
SYTSYNGTI_2251(sll0208)
SYSSYNPCCN_2250(sll0208)
SYQSYNPCCP_2250(sll0208)
SYJD082_05310
SYOC7I86_11775
SYCsyc0050_d
SYUM744_09020
SYFSynpcc7942_1593
SYDSyncc9605_0728
SYESyncc9902_1635
SYGsync_1990
SYRSynRCC307_1586
SYXSynWH7803_0654
CYACYA_0415
CYBCYB_2442
SYNESyn6312_2280
SYNPSyn7502_03278
SYNKKR100_05365
SYNRKR49_12745
SYNDKR52_13300
SYHSyncc8109_1976
SYNWSynWH8103_01989
SYNCCB0101_00310 CB0101_04550
DSLDacsa_2178
SYWSYNW1738
CGCCyagr_0039 Cyagr_1038
CYICBM981_0849
PMAPro_0532
PMMPMM0532
PMTPMT_1231
PMNPMN2A_1863
PMIPMT9312_0532
PMBA9601_05881
PMCP9515_05961
PMFP9303_07791
PMGP9301_05581
PMHP9215_06131
PMJP9211_05351
PMENATL1_05881
PRCEW14_0578
PRMEW15_0629
CMPCha6605_4153
AMRAM1_4041
TVNNIES2134_112420
SLWBRW62_00110
TELtll1313
THNNK55_03185
THECFFX45_09780
LENLEP3755_23570
LETO77CONTIG1_03123
LBOLBWT_14420
KOVK9N68_11180
LSCKIK02_13615
LSKJ5X98_02335
PSEUPse7367_3626
PSERABRG53_3065 ABRG53_4148
THEUHPC62_04755
GLPGlo7428_0150
GEEGM3708_2118
MARMAE_53090
MPKVL20_1523
MIQB5D77_20960
MVZmyaer102_25860
CANCyan10605_1692
HAOPCC7418_0961
ENNFRE64_14810
CYUUCYN_05810
CYTcce_0778
CWACwatDRAFT_5731
CYPPCC8801_0455
CYHCyan8802_0468
CYNCyan7425_0398 Cyan7425_2986
TERTery_2280
ARPNIES39_M01940
PAGHNIES204_11570
OXYHCG48_15940
MVAGD0A34_07475
LFSHFV01_13745
MICMic7113_4535
GEIGEI7407_1564
OACOscil6304_2075
ONIOsc7112_0944
PHORJWS08_08190
CEPCri9333_4418
GVIgll3146
GLJGKIL_0725
GMLISF26_16235
ANAalr5283
NPUNpun_R1711
NOSNos7107_1028
NOPNos7524_4304
NONNOS3756_54760
NFLCOO91_03200
NOECLI64_08835
NSHGXM_04007
NEDHUN01_28135
AVAAva_2533
NAZAazo_3371
ANBANA_C11210
ACYAnacy_3389
AWAAA650_00525
ANNEH233_18775
CSGCylst_0697
RSINB6N60_03104
CALOCal7507_5586
CALTCal6303_4369
CALHIJ00_07390
RIVRiv7116_3790
FISFIS3754_06310
DOUBMF77_02261
DFSHGD76_06335
CCURIAR63_11970
AFLOHEQ12_03505
TOQHCG51_19270
NCNBZZ01_14980
CTHEChro_1554
CEOETSB_0877
CERRGRSB_0833
RHOZGXP67_04270
ADDHUW48_09015
 » show all
Reference
1  [PMID:6593720]
  Authors
Cheesbrough TM, Kolattukudy PE.
  Title
Alkane biosynthesis by decarbonylation of aldehydes catalyzed by a particulate preparation from Pisum sativum.
  Journal
Proc Natl Acad Sci U S A 81:6613-7 (1984)
DOI:10.1073/pnas.81.21.6613
Reference
2  [PMID:20671186]
  Authors
Schirmer A, Rude MA, Li X, Popova E, del Cardayre SB
  Title
Microbial biosynthesis of alkanes.
  Journal
Science 329:559-62 (2010)
DOI:10.1126/science.1187936
  Sequence
Reference
3  [PMID:21341652]
  Authors
Warui DM, Li N, Norgaard H, Krebs C, Bollinger JM Jr, Booker SJ
  Title
Detection of formate, rather than carbon monoxide, as the stoichiometric coproduct in conversion of fatty aldehydes to alkanes by a cyanobacterial aldehyde decarbonylase.
  Journal
J Am Chem Soc 133:3316-9 (2011)
DOI:10.1021/ja111607x
  Sequence
Reference
4  [PMID:22947199]
  Authors
Li N, Chang WC, Warui DM, Booker SJ, Krebs C, Bollinger JM Jr
  Title
Evidence for only oxygenative cleavage of aldehydes to alk(a/e)nes and formate by cyanobacterial aldehyde decarbonylases.
  Journal
Biochemistry 51:7908-16 (2012)
DOI:10.1021/bi300912n
Other DBs
ExplorEnz - The Enzyme Database: 4.1.99.5
IUBMB Enzyme Nomenclature: 4.1.99.5
ExPASy - ENZYME nomenclature database: 4.1.99.5
BRENDA, the Enzyme Database: 4.1.99.5
CAS: 94185-90-7
LinkDB

KEGG   REACTION: R09466
Entry
R09466                      Reaction                               
Name
aldehyde decarbonylase
Definition
Long-chain aldehyde <=> Alkane + CO
Equation
Enzyme
Pathway
rn00073  Cutin, suberine and wax biosynthesis
rn01110  Biosynthesis of secondary metabolites
Orthology
K15404  aldehyde decarbonylase [EC:4.1.99.5]
LinkDB

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