KEGG   ORTHOLOGY: K15751
Entry
K15751                      KO                                     
Symbol
carAa
Name
carbazole 1,9a-dioxygenase [EC:1.14.12.22]
Pathway
map00621  Dioxin degradation
map01100  Metabolic pathways
map01120  Microbial metabolism in diverse environments
map01220  Degradation of aromatic compounds
Module
M00544  Carbazole degradation, carbazole => 2-oxopent-4-enoate + anthranilate
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00621 Dioxin degradation
    K15751  carAa; carbazole 1,9a-dioxygenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.12  With NADH or NADPH as one donor, and incorporation of two atoms of oxygen into the other donor
    1.14.12.22  carbazole 1,9a-dioxygenase
     K15751  carAa; carbazole 1,9a-dioxygenase
Dioxygenases [br01602.html]
 Dioxygenases in aromatic ring cleavage
  K15751
Other DBs
RN: R05414 R09512
GO: 0018564
Genes
PSD: DSC_14580
PRE: PCA10_p0280(carAa)
TTU: TERTU_1259
CYQ: Q91_0967
CZA: CYCME_1637
CYY: CPC19_07895
MGEO: CFI10_14605
GBI: PG2T_01265
PNR: AT302_13290
PFIB: PI93_011740
SSAN: NX02_18955
AG: ADC31794(carAa)
 » show all
Reference
PMID:9244274
  Authors
Sato SI, Nam JW, Kasuga K, Nojiri H, Yamane H, Omori T
  Title
Identification and characterization of genes encoding carbazole 1,9a-dioxygenase in Pseudomonas sp. strain CA10.
  Journal
J Bacteriol 179:4850-8 (1997)
DOI:10.1128/JB.179.15.4850-4858.1997
  Sequence
Reference
  Authors
Gai Z, Wang X, Liu X, Tai C, Tang H, He X, Wu G, Deng Z, Xu P
  Title
The genes coding for the conversion of carbazole to catechol are flanked by IS6100 elements in Sphingomonas sp. strain XLDN2-5.
  Journal
PLoS One 5:e10018 (2010)
DOI:10.1371/journal.pone.0010018
  Sequence
LinkDB

KEGG   ORTHOLOGY: K15752
Entry
K15752                      KO                                     
Symbol
carAc
Name
carbazole 1,9a-dioxygenase ferredoxin component
Pathway
map00621  Dioxin degradation
map01100  Metabolic pathways
map01120  Microbial metabolism in diverse environments
map01220  Degradation of aromatic compounds
Module
M00544  Carbazole degradation, carbazole => 2-oxopent-4-enoate + anthranilate
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00621 Dioxin degradation
    K15752  carAc; carbazole 1,9a-dioxygenase ferredoxin component
Dioxygenases [br01602.html]
 Dioxygenases in aromatic ring cleavage
  K15752
Other DBs
RN: R05414 R09512
Genes
PSD: DSC_09140
PRE: PCA10_p0320(carAc)
RBU: PG1C_11605
Reference
PMID:9244274
  Authors
Sato SI, Nam JW, Kasuga K, Nojiri H, Yamane H, Omori T
  Title
Identification and characterization of genes encoding carbazole 1,9a-dioxygenase in Pseudomonas sp. strain CA10.
  Journal
J Bacteriol 179:4850-8 (1997)
DOI:10.1128/JB.179.15.4850-4858.1997
  Sequence
Reference
  Authors
Gai Z, Wang X, Liu X, Tai C, Tang H, He X, Wu G, Deng Z, Xu P
  Title
The genes coding for the conversion of carbazole to catechol are flanked by IS6100 elements in Sphingomonas sp. strain XLDN2-5.
  Journal
PLoS One 5:e10018 (2010)
DOI:10.1371/journal.pone.0010018
LinkDB

KEGG   ORTHOLOGY: K15753
Entry
K15753            Tight     KO                                     
Symbol
carAd
Name
carbazole 1,9a-dioxygenase ferredoxin reductase component
Pathway
map00621  Dioxin degradation
map01100  Metabolic pathways
map01120  Microbial metabolism in diverse environments
map01220  Degradation of aromatic compounds
Module
M00544  Carbazole degradation, carbazole => 2-oxopent-4-enoate + anthranilate
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00621 Dioxin degradation
    K15753  carAd; carbazole 1,9a-dioxygenase ferredoxin reductase component
Dioxygenases [br01602.html]
 Dioxygenases in aromatic ring cleavage
  K15753
Other DBs
RN: R05414 R09512
Genes
PRE: PCA10_p0340(carAd)
Reference
PMID:9244274
  Authors
Sato SI, Nam JW, Kasuga K, Nojiri H, Yamane H, Omori T
  Title
Identification and characterization of genes encoding carbazole 1,9a-dioxygenase in Pseudomonas sp. strain CA10.
  Journal
J Bacteriol 179:4850-8 (1997)
DOI:10.1128/JB.179.15.4850-4858.1997
  Sequence
LinkDB

KEGG   REACTION: R05414
Entry
R05414                      Reaction                               
Name
9H-carbazole,NADH:oxygen oxidoreductase (2,3-hydroxylating)
Definition
Carbazole + Oxygen + NADH + H+ <=> 2'-Aminobiphenyl-2,3-diol + NAD+
Equation
Comment
NADPH (see R09512)
Reaction class
RC00001  C00003_C00004
RC01370  C08060_C08061
Enzyme
Pathway
rn00621  Dioxin degradation
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
rn01220  Degradation of aromatic compounds
Module
M00544  Carbazole degradation, carbazole => 2-oxopent-4-enoate + anthranilate
Orthology
K15751  carbazole 1,9a-dioxygenase [EC:1.14.12.22]
K15752  carbazole 1,9a-dioxygenase ferredoxin component
K15753  carbazole 1,9a-dioxygenase ferredoxin reductase component
Other DBs
RHEA: 27841
LinkDB

KEGG   REACTION: R09512
Entry
R09512                      Reaction                               
Name
9H-carbazole,NADPH:oxygen oxidoreductase (2,3-hydroxylating)
Definition
Carbazole + NADPH + H+ + Oxygen <=> 2'-Aminobiphenyl-2,3-diol + NADP+
Equation
Comment
NADH (see R05414)
Reaction class
RC00001  C00005_C00006
RC01370  C08060_C08061
Enzyme
Pathway
rn00621  Dioxin degradation
rn01120  Microbial metabolism in diverse environments
rn01220  Degradation of aromatic compounds
Module
M00544  Carbazole degradation, carbazole => 2-oxopent-4-enoate + anthranilate
Orthology
K15751  carbazole 1,9a-dioxygenase [EC:1.14.12.22]
K15752  carbazole 1,9a-dioxygenase ferredoxin component
K15753  carbazole 1,9a-dioxygenase ferredoxin reductase component
Other DBs
RHEA: 27845
LinkDB

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