Entry
Name
3-ketosteroid 9alpha-monooxygenase;
KshA;
3-ketosteroid 9alpha-hydroxylase
Class
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
BRITE hierarchy
Sysname
androsta-1,4-diene-3,17-dione,[reduced ferredoxin]:oxygen oxidoreductase (9alpha-hydroxylating)
Reaction(IUBMB)
androsta-1,4-diene-3,17-dione + 2 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + O2 = 9alpha-hydroxyandrosta-1,4-diene-3,17-dione + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O [RN:
R09860 ]
Reaction(KEGG)
Substrate
androsta-1,4-diene-3,17-dione [CPD:
C20144 ];
reduced ferredoxin [iron-sulfur] cluster [CPD:
C00138 ];
H+ [CPD:
C00080 ];
O2 [CPD:
C00007 ]
Product
9alpha-hydroxyandrosta-1,4-diene-3,17-dione [CPD:
C14909 ];
oxidized ferredoxin [iron-sulfur] cluster [CPD:
C00139 ];
H2O [CPD:
C00001 ]
Comment
The enzyme is involved in the cholesterol degradation pathway of several bacterial pathogens, such as Mycobacterium tuberculosis. It forms a two-component system with a ferredoxin reductase (KshB). The enzyme contains a Rieske-type iron-sulfur center and non-heme iron. The product of the enzyme is unstable, and spontaneously converts to 3-hydroxy-9,10-seconandrost-1,3,5(10)-triene-9,17-dione.
History
EC 1.14.15.30 created 2012 as EC 1.14.13.142, transferred 2018 to EC 1.14.15.30
Pathway
ec01120 Microbial metabolism in diverse environments
Orthology
K15982 3-ketosteroid 9alpha-monooxygenase subunit A
K15983 3-ketosteroid 9alpha-monooxygenase subunit B
Genes
RGL : CS053_01730 CS053_01930
VAF : D1115_22765 D1115_23260
PRE : PCA10_12240(kshA) PCA10_43650(kshB)
PFUW : KF707C_11570 KF707C_11880
PPUT : L483_14105 L483_14320
PPUN : PP4_26740(kshA) PP4_27180(kshB)
PVR : PverR02_11715 PverR02_11735
PPUU : PputUW4_01666 PputUW4_01678
PKC : PKB_4313(ksha1) PKB_4319(kshB) PKB_4338(ksha3)
PLQ : AA042_00420 AA042_20380
PPSY : AOC04_06430 AOC04_07880
PSET : THL1_1304 THL1_4407
PSIL : PMA3_11750 PMA3_11875
PKE : DLD99_14675 DLD99_14730
PUM : HGP31_20625 HGP31_20745
PPSH : G5J76_13535 G5J76_17295
PLAL : FXN65_05725 FXN65_21125
PKH : JLK41_05750 JLK41_05865
PAZE : KSS91_19205 KSS91_19265
PTAE : NCTC10697_01839(kshA) NCTC10697_02066(hmp_2)
PCAV : D3880_17050 D3880_17450
PPHN : HU825_08370 HU825_14425 HU825_14710
PIZ : LAB08_R40790 LAB08_R40910
PKM : PZ739_11585 PZ739_11800
PSHS : JJN09_05450 JJN09_05500
PLAU : I0D68_06090 I0D68_06150
PFOU : OZ911_14120 OZ911_14335
PSKP : KU43P_19160 KU43P_19490
PBM : CL52_03850 CL52_10355
SDEG : GOM96_01420 GOM96_01715 GOM96_13715
HARR : HV822_17640 HV822_17935
PPHA : BVH74_17575 BVH74_17920
HASM : QAO71_12390 QAO71_12475
COLW : A3Q33_18555 A3Q33_18810
CBER : B5D82_11010 B5D82_11285
PTN : PTRA_a1005(kshB) PTRA_a2590(kshA)
PNG : PNIG_a1057(kshB) PNIG_a2784(kshA)
SNAN : I6N98_00555 I6N98_01445 I6N98_05770 I6N98_10760
ZAL : AZF00_00470 AZF00_04635 AZF00_12085 AZF00_12900 AZF00_15655
AFUS : EYZ66_12990 EYZ66_13035
PAQM : E0F26_07235 E0F26_07250 E0F26_07320
ALCA : ASALC70_02445(kshA)
MSEC : LN244_04810 LN244_04920
MRZ : KDW95_00805 KDW95_00865
ENW : MJO57_10955 MJO57_21295
EMP : EZMO1_1334(kshB) EZMO1_1339(kshA) EZMO1_2690 EZMO1_3801
SOK : D0B54_03435 D0B54_05260 D0B54_05645 D0B54_08470 D0B54_08675
FCE : JN531_005745 JN531_007625
RIN : ACS15_4367 ACS15_4387 ACS15_4390
REH : H16_B0643(h16_B0643) H16_B0672(hcaE)
CNC : CNE_2c05890 CNE_2c06190(kshA) CNE_BB1p00120(kshA)
CUH : BJN34_30925 BJN34_31150
REU : Reut_A1546 Reut_A1576
CTI : RALTA_B0492 RALTA_B0514
CBW : RR42_m2029 RR42_s2318 RR42_s2340
COX : E0W60_08160 E0W60_08305
CUK : KB879_20655 KB879_20805
BUR : Bcep18194_B1416 Bcep18194_B1448
BCEN : DM39_3466 DM39_6206(hmp) DM39_6233(kshA)
BCT : GEM_4012 GEM_4096 GEM_4102
BCED : DM42_6314(hmp) DM42_6338(kshA)
BCEP : APZ15_30835 APZ15_31110
BPYR : ABD05_27655 ABD05_27770
BCON : NL30_03965 NL30_04080
BDF : WI26_21190 WI26_21235 WI26_21355
BTEI : WS51_05735 WS51_05845
BPSL : WS57_05865 WS57_06000 WS57_06445
BMEC : WJ16_26825 WJ16_26955
BSTL : BBJ41_21390 BBJ41_21510 BBJ41_35425
BANN : JFN94_25695 JFN94_25735 JFN94_26155
BARI : NLX30_30000 NLX30_30120 NLX30_35345
BAEN : L3V59_21795 L3V59_21920
BURK : DM992_32470 DM992_32590
PBRY : NDK50_32895 NDK50_32990
PPAI : E1956_08275 E1956_20140 E1956_37110 E1956_37205
PVE : UC34_06905 UC34_06920
CABA : SBC2_48790(kshB_1) SBC2_48980(kshA)
CTT : CtCNB1_1306 CtCNB1_1359
CTES : O987_07520 O987_07770
CRJ : QMY55_06885 QMY55_07050
DIH : G7047_09735 G7047_10060
SMIO : CATMQ487_31540 CATMQ487_31940
AZI : AzCIB_1457 AzCIB_1462
AZD : CDA09_09680 CDA09_09705
THU : AC731_008070 AC731_008185
THAU : C4PIVTH_4166(kshB) C4PIVTH_4177
THAG : CKCBHOJB_02264(kshB) CKCBHOJB_02279(kshA)
NAR : Saro_3601 Saro_3649 Saro_3666
NOT : C7W88_20195 C7W88_20485 C7W88_20690
SWI : Swit_1829 Swit_2053 Swit_3307
SPHD : HY78_09015 HY78_15255 HY78_16435
RDI : CMV14_16795 CMV14_16825
SPHM : G432_11540 G432_14050 G432_14385 G432_16975
SSAN : NX02_07805 NX02_17130
SKR : BRX40_00225 BRX40_00230
SPKC : KC8_00700 KC8_06855 KC8_08825 KC8_10270 KC8_14070 KC8_16645 KC8_19680
SPHB : EP837_02947 EP837_03216 EP837_03246 EP837_03584 EP837_03637
SPHJ : BSL82_11680 BSL82_11870
PHAO : HF685_05250 HF685_05340 HF685_05370
NTD : EGO55_02315 EGO55_02665 EGO55_03045 EGO55_04130 EGO55_13445 EGO55_16290 EGO55_16310
CAEN : K5X80_01135 K5X80_05620 K5X80_05965 K5X80_14960
MRM : A7982_01269 A7982_10481
MTU : Rv3526(kshA) Rv3571(kshB)
MRA : MRA_3565 MRA_3610(hmp)
MTF : TBFG_13559 TBFG_13604
MTB : TBMG_03565 TBMG_03610
MTK : TBSG_03592 TBSG_03637
MTZ : TBXG_003541 TBXG_003585
MTG : MRGA327_21785 MRGA327_22045
MTE : CCDC5079_3267 CCDC5079_3312
MTUR : CFBS_3742 CFBS_3788(hmp)
MTL : CCDC5180_3219 CCDC5180_3264
MTO : MTCTRI2_3590 MTCTRI2_3636(hmp)
MTD : UDA_3526 UDA_3571(hmp)
MTN : ERDMAN_3866 ERDMAN_3918(hmp)
MTJ : J112_18980 J112_19230
MTUB : MT7199_3587 MT7199_3634
MTUE : J114_18850 J114_19100
MTX : M943_18130 M943_18365
MTUH : I917_24735 I917_25090
MTUL : TBHG_03466 TBHG_03512
MTUT : HKBT1_3727 HKBT1_3773(hmp)
MTUU : HKBT2_3736 HKBT2_3782(hmp)
MTQ : HKBS1_3739 HKBS1_3785(hmp)
MBO : BQ2027_MB3556(ksha) BQ2027_MB3602(kshb)
MBB : BCG_3590 BCG_3636(hmp)
MBT : JTY_3591 JTY_3637(hmp)
MBM : BCGMEX_3588 BCGMEX_3634(hmp)
MBK : K60_036610 K60_037090
MAF : MAF_35380 MAF_35840(hmp)
MMIC : RN08_3901 RN08_3948
MCE : MCAN_35371 MCAN_35841(hmp)
MCQ : BN44_110015 BN44_110066(hmp)
MCV : BN43_90021 BN43_90072(hmp)
MCX : BN42_90018 BN42_90069(hmp)
MCZ : BN45_100018 BN45_100085(hmp)
MORY : MO_003682(kshA) MO_003730(kshB)
MPA : MAP_0496c MAP_1434 MAP_2377 MAP_2882c
MAO : MAP4_0925 MAP4_1446 MAP4_2411 MAP4_3328 MAP4_3371
MAVI : RC58_04545 RC58_07170 RC58_11985 RC58_16505 RC58_16720
MAVU : RE97_04545 RE97_07170 RE97_11995 RE97_16540 RE97_16755
MAV : MAV_0590 MAV_0633 MAV_1603 MAV_1857 MAV_3037 MAV_3666
MIT : OCO_04980 OCO_05430 OCO_28760 OCO_34910 OCO_37890
MIA : OCU_05020 OCU_05470 OCU_28620 OCU_34960 OCU_37970
MID : MIP_00939 MIP_00998 MIP_03683 MIP_05257 MIP_05742
MYO : OEM_05040 OEM_05500 OEM_27250 OEM_35350 OEM_38530
MCHI : AN480_02490 AN480_02715 AN480_15050 AN480_18495 AN480_19995
MIR : OCQ_05140 OCQ_05580 OCQ_27340 OCQ_36130 OCQ_39120
MMAL : CKJ54_02420 CKJ54_02640 CKJ54_13075 CKJ54_16420 CKJ54_18030
MMAN : MMAN_03030 MMAN_10160 MMAN_41010 MMAN_41330 MMAN_47930(hmp) MMAN_48390(kshA)
MSER : MTY59_16610 MTY59_24270(hmp) MTY59_24740(kshA) MTY59_44720 MTY59_52560
MSA : Mycsm_04176 Mycsm_04590 Mycsm_05671 Mycsm_05761 Mycsm_05841
MUL : MUL_2161 MUL_4089 MUL_4142(hmp)
MMI : MMAR_1935 MMAR_5015 MMAR_5066(hmp)
MMAE : MMARE11_18630 MMARE11_48250 MMARE11_48810(hmp)
MLI : MULP_02106 MULP_05266 MULP_05324(hmp)
MPSE : MPSD_19540 MPSD_52140(kshA) MPSD_52670(hmp)
MSHO : MSHO_04870(kshA) MSHO_05500(hmp) MSHO_52600
MMC : Mmcs_0296 Mmcs_0319 Mmcs_1788 Mmcs_3569 Mmcs_3712 Mmcs_4640 Mmcs_4710
MKM : Mkms_0306 Mkms_0329 Mkms_1835 Mkms_3642 Mkms_3785 Mkms_4728 Mkms_4796
MJL : Mjls_0287 Mjls_0310 Mjls_1769 Mjls_3574 Mjls_3725 Mjls_4115 Mjls_5022 Mjls_5095
MMM : W7S_02435 W7S_02660 W7S_13945 W7S_17465 W7S_18975
MKN : MKAN_11805 MKAN_12135 MKAN_24985
MYV : G155_01230 G155_03705 G155_04100 G155_04260 G155_04755 G155_07820 G155_09255 G155_10850 G155_24375 G155_26490
MYE : AB431_00270 AB431_11155 AB431_15090 AB431_17425 AB431_24925 AB431_26315 AB431_26560
MHAD : B586_04440 B586_04665
MDX : BTO20_04370 BTO20_24105 BTO20_26115 BTO20_31150 BTO20_33265
MSHG : MSG_00805(kshA_1) MSG_01415 MSG_01753 MSG_02466 MSG_04513(kshA_2) MSG_04564(hmp)
MFJ : MFLOJ_08010 MFLOJ_15040 MFLOJ_37900 MFLOJ_40640(hmp) MFLOJ_41090(kshA)
MSTO : MSTO_09240 MSTO_16460 MSTO_41650 MSTO_44590(hmp) MSTO_45060(kshA)
MSIM : MSIM_05770 MSIM_29080(hmp) MSIM_29510 MSIM_53050
MSAK : MSAS_01950 MSAS_05490 MSAS_28680(kshA) MSAS_29180(hmp) MSAS_55210
MKU : I2456_13035 I2456_25455 I2456_25690
MLW : MJO58_09530 MJO58_12925 MJO58_24865 MJO58_25105 MJO58_26420
MXE : MYXE_05050(hmp) MYXE_06210 MYXE_09820
MNV : MNVI_10350 MNVI_10880 MNVI_11900 MNVI_12100(kshA) MNVI_12540(hmp)
MPAG : C0J29_08865 C0J29_19365 C0J29_22020 C0J29_27500 C0J29_27840
MNM : MNVM_02730 MNVM_19150 MNVM_19370 MNVM_23420(hmp) MNVM_24080(kshA) MNVM_25620 MNVM_27170
MGOR : H0P51_05885 H0P51_07835 H0P51_17940 H0P51_25550 H0P51_25880
MCOO : MCOO_16460 MCOO_24770 MCOO_26240 MCOO_26790(kshA) MCOO_27340(hmp) MCOO_32620
MBAI : MB901379_01756(kshA_1) MB901379_04408(kshA_3) MB901379_04455(hmp_2)
MSEO : MSEO_05640 MSEO_08800 MSEO_12570 MSEO_34070(kshA) MSEO_34590(hmp)
MHEK : JMUB5695_00466(hmp) JMUB5695_00520 JMUB5695_00538 JMUB5695_00733 JMUB5695_00940
MGAU : MGALJ_04040 MGALJ_04550 MGALJ_23030 MGALJ_25620 MGALJ_30410 MGALJ_31940 MGALJ_37890(kshA) MGALJ_38590(kshB)
MLJ : MLAC_00150(kshA_1) MLAC_47210(hmp) MLAC_47870(kshA_2)
MBRD : MBRA_19980(hmp) MBRA_20460(kshA) MBRA_22880 MBRA_33050 MBRA_50470
MSHJ : MSHI_38510(hmp) MSHI_39140
MMAM : K3U93_08570 K3U93_11775 K3U93_22435 K3U93_22700
MSPG : F6B93_00890 F6B93_12430 F6B93_20245 F6B93_20500
MOT : LTS72_00025 LTS72_15090 LTS72_27905
MPAA : MKK62_02380 MKK62_02645 MKK62_02840 MKK62_09895
MKY : IWGMT90018_16290 IWGMT90018_22640 IWGMT90018_56870(kshA) IWGMT90018_57530(hmp)
MADI : A7U43_00470 A7U43_06650 A7U43_07045 A7U43_23205
MWU : PT015_07635 PT015_14380 PT015_15120 PT015_15320 PT015_15575
MYW : BVC93_08770 BVC93_08860 BVC93_09290 BVC93_20540
MSM : MSMEG_0734 MSMEG_2870 MSMEG_2893 MSMEG_5925 MSMEG_6039
MSG : MSMEI_2796 MSMEI_2819(hmp) MSMEI_5766 MSMEI_5878(hmp)
MSB : LJ00_14275 LJ00_14390 LJ00_29300 LJ00_29855
MSN : LI99_14280 LI99_14395 LI99_29305 LI99_29860
MSH : LI98_14285 LI98_14400 LI98_29310 LI98_29865
MVA : Mvan_2012 Mvan_2869 Mvan_2893 Mvan_4186 Mvan_5211 Mvan_5225 Mvan_5309
MGI : Mflv_1462 Mflv_1533 Mflv_1546 Mflv_2468 Mflv_4333 Mflv_4566
MSP : Mspyr1_09170 Mspyr1_09300 Mspyr1_18940 Mspyr1_21920 Mspyr1_36780 Mspyr1_39660 Mspyr1_47050
MCB : Mycch_1569 Mycch_1592 Mycch_1754 Mycch_3303 Mycch_3622 Mycch_4570 Mycch_4587 Mycch_4676
MNE : D174_08275 D174_24200 D174_24715
MYN : MyAD_08130 MyAD_21895 MyAD_23740 MyAD_24250
MFT : XA26_02660 XA26_06910 XA26_07730 XA26_08090 XA26_09130 XA26_15580 XA26_18510 XA26_22320 XA26_49330 XA26_53640
MPHL : MPHLCCUG_00490(hmp_1) MPHLCCUG_00577(kshA_1) MPHLCCUG_00595(kshA_2) MPHLCCUG_01870(kshA_3) MPHLCCUG_01926(kshA_4) MPHLCCUG_02604(kshA_6) MPHLCCUG_03747(hmp_4)
MVQ : MYVA_1646 MYVA_1666(kshB) MYVA_1911 MYVA_3602 MYVA_3985 MYVA_5096(kshA) MYVA_5113 MYVA_5219
MLL : B1R94_00400 B1R94_14190 B1R94_20075 B1R94_20210 B1R94_20780 B1R94_24935 B1R94_25475
MRH : MycrhN_2242 MycrhN_2306 MycrhN_3476 MycrhN_4240 MycrhN_6043 MycrhN_6097
MTHN : 4412656_00372(kshA_2) 4412656_00943(kshA_4) 4412656_00961(hmp_2) 4412656_01450(kshA_5) 4412656_03040(hmp_3) 4412656_03259(kshA_6) 4412656_04042(kshA_8) 4412656_04095(hmp_6)
MHAS : MHAS_00793(kshA_2) MHAS_00844(kshA_3) MHAS_02479(kshA_4) MHAS_02573(kshB) MHAS_03041(kshA_5) MHAS_03182(kshA_7) MHAS_03697(kshA_8) MHAS_03711(kshA_9) MHAS_03780(hmp)
MDU : MDUV_04890 MDUV_07840 MDUV_19840 MDUV_19850 MDUV_19890 MDUV_24890 MDUV_26640 MDUV_26870 MDUV_31180 MDUV_31190 MDUV_48980(kshB) MDUV_49830(kshA) MDUV_49950
MCHT : MCHIJ_12540 MCHIJ_12740 MCHIJ_12900 MCHIJ_19280(kshB) MCHIJ_20060(kshA) MCHIJ_21220 MCHIJ_47580
MAUU : NCTC10437_01869(kshA_1) NCTC10437_02719(kshA_2) NCTC10437_02741(hmp_2) NCTC10437_03541(kshA_3) NCTC10437_03926(hmp_3) NCTC10437_04973(kshA_5) NCTC10437_04990(kshA_6) NCTC10437_05070(hmp_5)
MMAG : MMAD_02700 MMAD_47870(kshA) MMAD_48600(kshB)
MMOR : MMOR_10320 MMOR_11730(kshB) MMOR_12370(kshA) MMOR_26640 MMOR_44820 MMOR_45300
MFX : MFAL_16460 MFAL_27870(kshA_1) MFAL_32570(kshB) MFAL_33700(kshA_2) MFAL_34890
MAIC : MAIC_05160(hmp) MAIC_05860(kshA) MAIC_07830 MAIC_26600 MAIC_30570 MAIC_56030
MIJ : MINS_00070(kshA_1) MINS_00720(kshB) MINS_06060 MINS_18900 MINS_42010 MINS_43000 MINS_43130(kshA_2)
MALV : MALV_16800 MALV_19850 MALV_21750 MALV_29210 MALV_29530 MALV_30220 MALV_33090 MALV_42110(kshB) MALV_42940(kshA) MALV_46370
MTY : MTOK_21970(kshB) MTOK_23000(kshA) MTOK_23190 MTOK_60760
MPSC : MPSYJ_15740(kshB) MPSYJ_16390(kshA) MPSYJ_16560 MPSYJ_29890
MARZ : MARA_20680 MARA_32980 MARA_47410(kshB) MARA_48540(kshA)
MGAD : MGAD_00940 MGAD_19550 MGAD_20060 MGAD_30280 MGAD_36970(kshA) MGAD_37710(kshB) MGAD_56920
MHEV : MHEL_21480 MHEL_27620(hmp) MHEL_28320(kshA) MHEL_44410 MHEL_49770 MHEL_50140
MSAR : MSAR_10460(kshA) MSAR_11000(hmp) MSAR_16650 MSAR_32120 MSAR_41460
MANY : MANY_15950 MANY_32520(kshA) MANY_33070(hmp) MANY_33930 MANY_37610
MAUB : MAUB_13170 MAUB_13780 MAUB_26190(kshA) MAUB_27110(kshB) MAUB_35870 MAUB_38560 MAUB_51360 MAUB_54660
MPOF : MPOR_23460 MPOR_39600 MPOR_53110 MPOR_53290(kshA) MPOR_54020(kshB)
MPHU : MPHO_14510 MPHO_31660 MPHO_34400 MPHO_43350(kshB) MPHO_44160(kshA_1) MPHO_45360 MPHO_55450(kshA_2)
MMUC : C1S78_000955 C1S78_002100 C1S78_009420 C1S78_011035 C1S78_018450 C1S78_019240 C1S78_019360 C1S78_019890 C1S78_024600 C1S78_025205 C1S78_025625
MMAT : MMAGJ_15440 MMAGJ_33750(kshB) MMAGJ_34960(kshA) MMAGJ_47430
MBOK : MBOE_03820(kshA) MBOE_04990(kshB) MBOE_18780 MBOE_19670 MBOE_20130 MBOE_42950 MBOE_56150 MBOE_59170 MBOE_60810
MFG : K6L26_05330 K6L26_05780 K6L26_16780 K6L26_23275 K6L26_27675 K6L26_27820 K6L26_28195
MSEI : MSEDJ_01820(kshA) MSEDJ_02540(kshB) MSEDJ_18360
MFLV : NCTC10271_00464(hmp_1) NCTC10271_00524(kshA_1) NCTC10271_02165(kshA_2) NCTC10271_03524(kshA_5) NCTC10271_03628(kshA_6)
MCEE : MCEL_05830 MCEL_17550 MCEL_18020 MCEL_37710(kshB) MCEL_38400(kshA)
MMON : EWR22_01585 EWR22_01700 EWR22_18415 EWR22_19145 EWR22_21125 EWR22_21130 EWR22_25090 EWR22_25475
MGO : AFA91_10575 AFA91_11130
MHOL : K3U96_03065 K3U96_03360 K3U96_09525 K3U96_17790 K3U96_18060
MSEN : K3U95_03580 K3U95_09605 K3U95_12885 K3U95_20520 K3U95_25050 K3U95_25525
MPAE : K0O64_00245 K0O64_10800 K0O64_14540 K0O64_20470 K0O64_24620 K0O64_25805 K0O64_26070
MRF : MJO55_17045 MJO55_23770 MJO55_23860 MJO55_24190
MDF : K0O62_02770 K0O62_15775 K0O62_15940 K0O62_25360 K0O62_25980
MCRO : MI149_00375 MI149_11665 MI149_15395 MI149_15520 MI149_21050 MI149_25025 MI149_26115 MI149_26370
MGRO : FZ046_02575 FZ046_02955 FZ046_08935
MAUS : JN090_13560 JN090_13660 JN090_19215 JN090_20410 JN090_25890 JN090_25960 JN090_26595
MKR : MKOR_24880 MKOR_35310(hmp) MKOR_35890(kshA) MKOR_36630
MPAK : MIU77_01960 MIU77_02235
MAB : MAB_0080c MAB_0583c MAB_0726 MAB_4173
MMV : MYCMA_0050 MYCMA_1991 MYCMA_2177 MYCMA_2322
MABB : MASS_0082 MASS_0552 MASS_3633 MASS_3931 MASS_4172
MABL : MMASJCM_0083 MMASJCM_0572 MMASJCM_3622 MMASJCM_3937 MMASJCM_4259
MCHE : BB28_00390 BB28_02780 BB28_18525 BB28_20180 BB28_21490 BB28_22430
MIZ : BAB75_00690 BAB75_03530 BAB75_20635 BAB75_22365 BAB75_23955
MSTE : MSTE_00075 MSTE_00540 MSTE_03759 MSTE_04090 MSTE_04349 MSTE_04547
MSAO : MYCSP_02485 MYCSP_15855 MYCSP_16680 MYCSP_18190 MYCSP_19530 MYCSP_20445
MSAL : DSM43276_00501(hmp_1) DSM43276_00643(kshA_1) DSM43276_03419(kshA_2) DSM43276_03727(hmp_4) DSM43276_04014(kshA_3)
MJD : JDM601_1615 JDM601_3357 JDM601_3518(hmp) JDM601_3668 JDM601_3855(hmp) JDM601_4248(hmp) JDM601_4270
MTER : 4434518_01527(kshA_1) 4434518_03344(kshA_2) 4434518_03494(hmp_1) 4434518_03640(kshA_3) 4434518_03730(hmp_2)
MMIN : MMIN_06680 MMIN_06920 MMIN_11900(kshA) MMIN_12550(hmp) MMIN_32160
MHIB : MHIB_10560 MHIB_23820 MHIB_24030 MHIB_27800 MHIB_29150 MHIB_30580(kshA) MHIB_31190(hmp)
MHER : K3U94_08890 K3U94_19910 K3U94_20720 K3U94_21035
MVM : MJO54_08985 MJO54_19815 MJO54_20640 MJO54_20930
ASD : AS9A_0920 AS9A_0922(kshA) AS9A_2419
NFA : NFA_22480 NFA_33560 NFA_33740 NFA_40990 NFA_4750 NFA_50680
NFR : ERS450000_00679(kshA_1) ERS450000_00697(kshA_2) ERS450000_01849(kshA_3) ERS450000_02931(kshA_4) ERS450000_03761(kshA_5) ERS450000_04823(hmp_4) ERS450000_05814(hmp_5)
NCY : NOCYR_0504 NOCYR_1557 NOCYR_2402 NOCYR_2420(ksh) NOCYR_2512 NOCYR_4851
NBR : O3I_002680 O3I_006885 O3I_038125
NNO : NONO_c05000 NONO_c21270 NONO_c33260 NONO_c36770 NONO_c43500 NONO_c44660 NONO_c51650(kshB1) NONO_c58770(kshB2) NONO_c58790(kshA) NONO_c68680
NSL : BOX37_02190 BOX37_11740 BOX37_11865 BOX37_15565 BOX37_18490 BOX37_27470 BOX37_29000
NSR : NS506_01263(kshA) NS506_02682 NS506_04325 NS506_06286 NS506_06779 NS506_06781 NS506_07836
NTP : CRH09_03320 CRH09_36350
NOZ : DMB37_16935 DMB37_23605 DMB37_40335
NOD : FOH10_00665 FOH10_14610 FOH10_16055 FOH10_20585 FOH10_22600 FOH10_22610 FOH10_28730
NAH : F5544_02645 F5544_20855 F5544_40650
NAD : NCTC11293_01248(kshA_1) NCTC11293_04392(kshA_2) NCTC11293_04411(hmp_1) NCTC11293_04696(hmp_2) NCTC11293_06443(hmp_4)
NWL : NWFMUON74_04960 NWFMUON74_14510 NWFMUON74_16510 NWFMUON74_27890 NWFMUON74_64550
NIE : KV110_03040 KV110_07440 KV110_37315
NTC : KHQ06_03660 KHQ06_09230 KHQ06_09790 KHQ06_26970 KHQ06_27550 KHQ06_35115 KHQ06_35125 KHQ06_37475
NHU : H0264_03865 H0264_09095 H0264_13430 H0264_27825 H0264_31525 H0264_34225 H0264_34235
NYA : LTV02_02155 LTV02_08320 LTV02_23905 LTV02_28875 LTV02_36570 LTV02_38685 LTV02_38695
NGP : LTT66_15435 LTT66_16795 LTT66_21200 LTT66_28755 LTT66_28765 LTT66_30525
NSPU : IFM12276_01710 IFM12276_04420 IFM12276_28680 IFM12276_30800 IFM12276_30810 IFM12276_31080
NYU : D7D52_04510 D7D52_06440 D7D52_07030 D7D52_09485 D7D52_09495 D7D52_10835 D7D52_14120 D7D52_24780 D7D52_29640
RHA : RHA1_ro02490 RHA1_ro04538(kshA) RHA1_ro05811 RHA1_ro05833(kshB) RHA1_ro06056 RHA1_ro09002(kshB) RHA1_ro09003(kshA)
RER : RER_07540(kshA) RER_09150(kshA2) RER_13800(kshA) RER_17750(kshB) RER_51130(kshA)
REY : O5Y_03665 O5Y_04070 O5Y_06500 O5Y_08515 O5Y_18435 O5Y_24235
REB : XU06_03905 XU06_04315 XU06_06760 XU06_08755 XU06_24655
RQI : C1M55_04145 C1M55_04545 C1M55_07005 C1M55_08985 C1M55_25820
ROP : ROP_22170(kshA) ROP_44530(kshA) ROP_58730(kshA2) ROP_58950(kshB) ROP_61150(kshB)
ROA : Pd630_LPD00990 Pd630_LPD02435 Pd630_LPD02458 Pd630_LPD02696 Pd630_LPD06716
RPY : Y013_08850 Y013_19020 Y013_19240 Y013_19255
RBY : CEJ39_05385 CEJ39_05605 CEJ39_05620 CEJ39_19740 CEJ39_21920
RAV : AAT18_03960 AAT18_18675 AAT18_21250 AAT18_21975
RHW : BFN03_03160 BFN03_15205
RRZ : CS378_08145 CS378_10105 CS378_10555 CS378_11435 CS378_19600
RHQ : IM25_00690 IM25_02790 IM25_08870
RHOD : AOT96_05570 AOT96_14540 AOT96_14950 AOT96_17400 AOT96_19355
RRT : 4535765_00581(kshA_1) 4535765_00622(kshA_2) 4535765_00625(kshB_1) 4535765_03583(hmp_2) 4535765_04053(kshA_4) 4535765_04385(kshB_2)
RCR : NCTC10994_02095(kshB_1) NCTC10994_02098(kshA_1) NCTC10994_02139(kshA_2) NCTC10994_02986(kshB_2) NCTC10994_03234(kshA_3) NCTC10994_03286(kshA_4) NCTC10994_03312(kshA_5) NCTC10994_03677(hmp_2)
RTM : G4H71_04465 G4H71_04560 G4H71_07400 G4H71_13750 G4H71_16250
RKO : JWS14_13070 JWS14_20720 JWS14_24480 JWS14_31790 JWS14_31900 JWS14_33035
RGO : KYT97_09650 KYT97_11690 KYT97_12275 KYT97_15615 KYT97_16665 KYT97_18410 KYT97_23230
ROZ : CBI38_00920 CBI38_01305 CBI38_01320 CBI38_04165 CBI38_04885 CBI38_20480
RPSK : JWS13_10920 JWS13_12010 JWS13_12120 JWS13_20445 JWS13_24105 JWS13_32815
RGOR : NMQ04_02510 NMQ04_02715 NMQ04_02730 NMQ04_15605 NMQ04_17470 NMQ04_17870
RHOP : D8W71_01860 D8W71_07945 D8W71_08085 D8W71_12555 D8W71_26920
RHOO : RA302_04015 RA302_04420 RA302_06890 RA302_08900 RA302_24860
RHOU : KZJ41_03955 KZJ41_19785 KZJ41_22380 KZJ41_23465
RHOW : A4U64_02515 A4U64_03410 A4U64_06035 A4U64_20815
RHOJ : JVH1_06050 JVH1_07190 JVH1_07300 JVH1_13640 JVH1_20470 JVH1_24730
RHS : A3Q41_00422(hmp_1) A3Q41_02260(hmp_2)
REQ : REQ_06790 REQ_08980(kshA) REQ_15470 REQ_36320 REQ_40110 REQ_42740 REQ_43730 REQ_45190
PDEF : P9209_04770 P9209_10125 P9209_27805 P9209_29080
WHR : OG579_02805 OG579_07530 OG579_14775 OG579_17630
GBR : Gbro_0320 Gbro_0919 Gbro_3782 Gbro_4325
GPO : GPOL_c00590 GPOL_c36520 GPOL_c41100(kshA1) GPOL_c41200(kshA2) GPOL_c41340 GPOL_c46160
GOR : KTR9_0819(kshA) KTR9_3740(kshB) KTR9_4196 KTR9_5394
GOQ : ACH46_03115 ACH46_03235 ACH46_15935
GTA : BCM27_00520 BCM27_04760 BCM27_04885 BCM27_05105 BCM27_19590 BCM27_22040 BCM27_22340
GOC : CXX93_06455 CXX93_06935
GIT : C6V83_04270 C6V83_16235
GRU : GCWB2_04170(kshA1) GCWB2_11625(kshA2) GCWB2_19200(hmp6) GCWB2_21220(hmp7) GCWB2_21605(kshA4)
GOM : D7316_02031(kshA_1) D7316_02407(hmp_2) D7316_02456(kshA_2) D7316_02565(kshA_3) D7316_02584(kshB_1) D7316_03108(kshA_4) D7316_04922(kshB_2)
GAV : C5O27_00865 C5O27_06840 C5O27_07040 C5O27_08940 C5O27_10695 C5O27_10760 C5O27_16275
GOD : GKZ92_00215 GKZ92_03965 GKZ92_16370 GKZ92_16435 GKZ92_18130 GKZ92_19660 GKZ92_20570
GOS : QAD21_00490 QAD21_04120 QAD21_18500 QAD21_21275
GOJ : GR168_00520 GR168_04245 GR168_17890 GR168_20355
GAM : GII34_03585 GII34_04990 GII34_18075 GII34_18815 GII34_19625
GPD : GII33_03230 GII33_03925 GII33_04450 GII33_17530 GII33_19165 GII33_21770 GII33_21775
GJI : H1R19_03895 H1R19_04045 H1R19_12650 H1R19_12715 H1R19_17950 H1R19_20600
GOI : LK459_05090 LK459_05150 LK459_06945 LK459_09025 LK459_15780
GHN : MVF96_00500 MVF96_04245 MVF96_18515 MVF96_21255
GAMI : IHQ52_00755 IHQ52_01025 IHQ52_06825 IHQ52_07705 IHQ52_22105
GMG : NWF22_03565 NWF22_12205 NWF22_14795 NWF22_14805 NWF22_15750
GSI : P5P27_15305 P5P27_15795
SPIN : KV203_03665 KV203_13540 KV203_17355
TPR : Tpau_3447 Tpau_3517 Tpau_3849 Tpau_3851
TSM : ASU32_19920 ASU32_20040 ASU32_21925 ASU32_21935
TPUL : TPB0596_37600(kshB) TPB0596_38260 TPB0596_41900 TPB0596_41920
TSD : MTP03_13380(kshB) MTP03_39520(hmp) MTP03_43350 MTP03_43370
DTM : BJL86_0694 BJL86_0697
DIT : C3V38_09250 C3V38_09260
DIZ : CT688_03170 CT688_03180
DPC : A6048_03115 A6048_03125 A6048_14145
DLU : A6035_03410 A6035_03420
DKN : NHB83_02960 NHB83_02970
DCD : VYL96_03195 VYL96_03205
TOY : FO059_00150 FO059_01345 FO059_05540 FO059_14015 FO059_14025 FO059_16350 FO059_17440 FO059_17470
SVT : SVTN_35870 SVTN_35880
SALU : DC74_7441 DC74_7443
SALL : SAZ_38410 SAZ_38420
SLX : SLAV_27410(kshA) SLAV_27420(hmp4)
SNK : CP967_03265 CP967_03300
SGX : H4W23_38505 H4W23_38515
SXN : IAG42_03495 IAG42_26625 IAG42_26635
SRUG : F0345_00790 F0345_00825
STAA : LDH80_36365 LDH80_36375
SNIG : HEK616_31380 HEK616_31400
STUB : MMF93_22435 MMF93_31665 MMF93_31800
SLON : LGI35_13860 LGI35_13870
MRN : K8F61_04970 K8F61_04990
ARL : AFL94_16990 AFL94_17000 AFL94_17140
ARY : ATC04_01230 ATC04_01245 ATC04_01315
ASUN : KG104_04210 KG104_04220
GPR : JQN66_16875 JQN66_16945 JQN66_16955
PAEY : KUF55_17910 KUF55_17955 KUF55_17965
JTE : ASJ30_13635 ASJ30_13640
NDK : I601_0574(kshA_1) I601_3442(hmp_2) I601_3444(kshA_2)
NBE : Back2_27910 Back2_27930
NANO : G5V58_10115 G5V58_10125
NARO : CFH99_05075 CFH99_13240 CFH99_13250
NPI : G7071_12480 G7071_12670 G7071_15685 G7071_15695
NPC : KUV85_04490 KUV85_04500 KUV85_12205
NMAR : HPC71_08845 HPC71_09745 HPC71_09755
NFC : KG111_07185 KG111_08645 KG111_08655 KG111_15355 KG111_15415
NBI : SHK19_12170 SHK19_12180
PSIM : KR76_14160 KR76_14170 KR76_18045 KR76_27070 KR76_27080
AEB : C6I20_03500 C6I20_03510
ACTW : F7P10_03565 F7P10_14665 F7P10_28350 F7P10_28445 F7P10_38145
AMAZ : LUW76_36055 LUW76_36145
ACIR : OG979_26430 OG979_26490
ACTQ : OG417_40225 OG417_40270
FRE : Franean1_2973 Franean1_3372 Franean1_4306
FRI : FraEuI1c_4270 FraEuI1c_5408
AJA : AJAP_26420(kshA) AJAP_26430(kshB)
AMQ : AMETH_4841 AMETH_4843
AMYC : CU254_10435 CU254_10445 CU254_23465 CU254_23475
AMYB : BKN51_04995 BKN51_05005
AAB : A4R43_16060 A4R43_16070
AMYY : YIM_14425(hmp1) YIM_14435(kshA1) YIM_36730(hmp4) YIM_36740(kshA2)
AORI : SD37_13460 SD37_13470
AACD : LWP59_17310 LWP59_23965 LWP59_29215 LWP59_29225
APRT : MUY14_23845 MUY14_23855
AROO : NQK81_09945 NQK81_09955
ATHM : L1857_26980 L1857_26990
ARHD : VSH64_01755 VSH64_01765
AMOG : QRX60_26315 QRX60_26325
ACYN : ORV05_07230 ORV05_07240
ACOR : LCL61_01220 LCL61_01230
PSDS : K1T35_06270 K1T35_06280
KUT : JJ691_08300 JJ691_08320
KPHY : AOZ06_42845 AOZ06_42855
LED : BBK82_38955 BBK82_38965
ALO : CRK57807 CRK57817 CRK59604 CRK59606
PMAD : BAY61_10930 BAY61_10940
SACE : GIY23_13370 GIY23_13380
ACTU : Actkin_05403(hmp_2)
CROS : N8J89_29405 N8J89_29415
STP : Strop_2672 Strop_2674
AMS : AMIS_19150 AMIS_19170
AIH : Aiant_18900 Aiant_18920(hmp)
ACTL : L3i22_084480 L3i22_084500
ASIC : Q0Z83_065600 Q0Z83_065620
AOU : ACTOB_004116 ACTOB_004118
ACTE : ACTI_41180(kshB) ACTI_41200
JCY : M6B22_17695 M6B22_17725 M6B22_21595
DHI : LH044_09460 LH044_11415
LEPV : J4558_00850 J4558_05720
» show all
Taxonomy
Reference
Authors
Petrusma M, Dijkhuizen L, van der Geize R
Title
Rhodococcus rhodochrous DSM 43269 3-ketosteroid 9alpha-hydroxylase, a two-component iron-sulfur-containing monooxygenase with subtle steroid substrate specificity.
Journal
Sequence
Reference
Authors
Capyk JK, D'Angelo I, Strynadka NC, Eltis LD
Title
Characterization of 3-ketosteroid 9{alpha}-hydroxylase, a Rieske oxygenase in the cholesterol degradation pathway of Mycobacterium tuberculosis.
Journal
Sequence
Reference
Authors
Capyk JK, Casabon I, Gruninger R, Strynadka NC, Eltis LD
Title
Activity of 3-ketosteroid 9alpha-hydroxylase (KshAB) indicates cholesterol side chain and ring degradation occur simultaneously in Mycobacterium tuberculosis.
Journal
Other DBs
LinkDB
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