KEGG   ORTHOLOGY: K16332
Entry
K16332                      KO                                     
Symbol
RBL2
Name
retinoblastoma-like protein 2
Pathway
map04068  FoxO signaling pathway
map04110  Cell cycle
map04151  PI3K-Akt signaling pathway
map04218  Cellular senescence
map05165  Human papillomavirus infection
map05203  Viral carcinogenesis
Disease
H02613  Brunet-Wagner neurodevelopmental syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04068 FoxO signaling pathway
    K16332  RBL2; retinoblastoma-like protein 2
   04151 PI3K-Akt signaling pathway
    K16332  RBL2; retinoblastoma-like protein 2
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    K16332  RBL2; retinoblastoma-like protein 2
   04218 Cellular senescence
    K16332  RBL2; retinoblastoma-like protein 2
 09160 Human Diseases
  09161 Cancer: overview
   05203 Viral carcinogenesis
    K16332  RBL2; retinoblastoma-like protein 2
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    K16332  RBL2; retinoblastoma-like protein 2
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K16332  RBL2; retinoblastoma-like protein 2
Transcription factors [BR:ko03000]
 Eukaryotic type
  Other transcription factors
   Pocket domain Rb
    K16332  RBL2; retinoblastoma-like protein 2
Genes
HSA: 5934(RBL2)
PTR: 467978(RBL2)
PPS: 100978830(RBL2)
GGO: 101138930(RBL2)
PON: 100444180(RBL2)
NLE: 100595276(RBL2)
MCC: 696992(RBL2)
MCF: 102118320(RBL2)
MTHB: 126944978
MNI: 105494099(RBL2)
CSAB: 103232914(RBL2)
CATY: 105588637(RBL2)
PANU: 101008150(RBL2)
TGE: 112613980(RBL2)
RRO: 104658250(RBL2)
RBB: 108531271(RBL2)
TFN: 117087785(RBL2)
PTEH: 111541247(RBL2)
CANG: 105514935(RBL2)
CJC: 100410298(RBL2)
SBQ: 101038159(RBL2)
CSYR: 103270226(RBL2)
MMUR: 105875529(RBL2)
LCAT: 123625011(RBL2)
PCOQ: 105817052(RBL2)
OGA: 100963426(RBL2)
MMU: 19651(Rbl2)
MCAL: 110300201(Rbl2)
MPAH: 110337191(Rbl2)
RNO: 81758(Rbl2)
MCOC: 116069845(Rbl2)
MUN: 110548204(Rbl2)
CGE: 100770221(Rbl2)
MAUA: 101835700(Rbl2)
PLEU: 114694542(Rbl2)
MORG: 121447599(Rbl2)
MFOT: 126502722
AAMP: 119802072(Rbl2)
NGI: 103731674(Rbl2)
HGL: 101701252(Rbl2)
CPOC: 100713872(Rbl2)
DORD: 105994406(Rbl2)
DSP: 122116275(Rbl2)
NCAR: 124966292
OCU: 100339977
OPI: 101521309(RBL2)
TUP: 102476721(RBL2)
GVR: 103594960(RBL2)
CFA: 478127(RBL2)
CLUD: 112660467(RBL2)
VVP: 112929613(RBL2)
VLG: 121496541(RBL2)
AML: 100463875(RBL2)
UMR: 103673796(RBL2)
UAH: 113252236(RBL2)
UAR: 123798407(RBL2)
ELK: 111157436
LLV: 125088702
MPUF: 101670573(RBL2)
NVS: 122911451(RBL2)
ORO: 101380168(RBL2)
EJU: 114199582(RBL2)
ZCA: 113935342(RBL2)
MLX: 118023785(RBL2)
NSU: 110594280(RBL2)
LWW: 102738079(RBL2)
FCA: 101097858(RBL2)
PYU: 121045294(RBL2)
PBG: 122494201(RBL2)
LRUF: 124511315
PTG: 102970305(RBL2)
PPAD: 109270926(RBL2)
AJU: 106984720(RBL2)
HHV: 120237907(RBL2)
BTA: 533294(RBL2)
BOM: 102271403(RBL2)
BIU: 109572446(RBL2)
BBUB: 102416097(RBL2)
BBIS: 105004344(RBL2)
CHX: 102181890(RBL2)
OAS: 101114800(RBL2)
ODA: 120873101(RBL2)
CCAD: 122420237(RBL2)
SSC: 100627715(RBL2)
CFR: 102524019(RBL2)
CBAI: 105075725(RBL2)
CDK: 105097515(RBL2)
VPC: 102527402(RBL2)
BACU: 103018620(RBL2)
LVE: 103074426(RBL2)
OOR: 101273431(RBL2)
DLE: 111164988(RBL2)
PCAD: 102976320(RBL2)
PSIU: 116743728(RBL2)
ECB: 100060431(RBL2)
EPZ: 103546526(RBL2)
EAI: 106822536(RBL2)
MYB: 102251179(RBL2)
MYD: 102761562(RBL2)
MMYO: 118674330(RBL2)
MLF: 102423035(RBL2)
MNA: 107543484(RBL2)
PKL: 118720487(RBL2)
HAI: 109383411(RBL2)
DRO: 112296681(RBL2)
SHON: 119001122(RBL2)
AJM: 119046452(RBL2)
PDIC: 114488173(RBL2)
PHAS: 123805724(RBL2)
MMF: 118639540(RBL2)
RFQ: 117034416(RBL2)
PALE: 102882545(RBL2)
PGIG: 120617273(RBL2)
PVP: 105292082(RBL2)
RAY: 107509673(RBL2)
MJV: 108388354(RBL2)
TOD: 119248895(RBL2)
SARA: 101542541(RBL2)
LAV: 100660308(RBL2)
TMU: 101360818
ETF: 101658150(RBL2)
DNM: 101437375(RBL2)
MDO: 100019136(RBL2)
GAS: 123237309(RBL2)
SHR: 100933451(RBL2)
PCW: 110207491(RBL2)
OAA: 100091282(RBL2)
GGA: 425111(RBL2)
PCOC: 116243978(RBL2)
MGP: 100547227(RBL2)
CJO: 107319080(RBL2)
NMEL: 110404552(RBL2)
APLA: 101789469(RBL2)
ACYG: 106045264(RBL2)
AFUL: 116493890(RBL2)
TGU: 100230395(RBL2)
LSR: 110484429(RBL2)
SCAN: 103816807(RBL2)
PMOA: 120507955(RBL2)
OTC: 121333779(RBL2)
PRUF: 121348771(RBL2)
GFR: 102044028(RBL2)
FAB: 101806783(RBL2)
PHI: 102106505(RBL2)
PMAJ: 107209759(RBL2)
CCAE: 111934599(RBL2)
CCW: 104687468(RBL2)
CBRC: 103620310
ETL: 114055169(RBL2) 114071728
ZAB: 102060989(RBL2)
ACHL: 103807663(RBL2)
FPG: 101910475(RBL2)
FCH: 102056460(RBL2)
CLV: 102098411(RBL2)
EGZ: 104125194(RBL2)
NNI: 104011263(RBL2)
PLET: 104622012(RBL2)
PCRI: 104028032(RBL2)
PCAO: 104048971
ACUN: 113484278(RBL2)
TALA: 104362259(RBL2)
PADL: 103914232(RBL2)
AFOR: 103896865(RBL2)
ACHC: 115345410(RBL2)
HALD: 104317212(RBL2)
HLE: 104842523(RBL2)
AGEN: 126041290
GCL: 127020946
CCRI: 104162668(RBL2)
CSTI: 104557388(RBL2)
EHS: 104507320(RBL2)
MUI: 104543047(RBL2)
FGA: 104073274(RBL2)
GSTE: 104259812(RBL2)
LDI: 104350626(RBL2)
MNB: 103768451(RBL2)
OHA: 104338967(RBL2)
NNT: 104401950(RBL2)
DPUB: 104303150(RBL2)
PGUU: 104468449(RBL2)
ACAR: 104527143(RBL2)
CPEA: 104388564(RBL2)
CVF: 104286467(RBL2)
CUCA: 104057286(RBL2)
TEO: 104381867(RBL2)
BRHI: 104495908(RBL2)
AAM: 106483200(RBL2)
AROW: 112967529(RBL2)
NPD: 112944968(RBL2)
TGT: 104570445(RBL2)
DNE: 112984384(RBL2)
SCAM: 104146319(RBL2)
ASN: 102372889(RBL2)
AMJ: 102575184(RBL2)
CPOO: 109310520(RBL2)
GGN: 109289609(RBL2)
PSS: 102445416(RBL2)
CMY: 102947067(RBL2)
CPIC: 101945444(RBL2)
TST: 117886474(RBL2)
CABI: 116839444(RBL2)
MRV: 120384339(RBL2)
ACS: 100556593(rbl2)
PVT: 110082483(RBL2)
SUND: 121914520(RBL2)
PBI: 103053051(RBL2)
PMUR: 107289912(RBL2)
CTIG: 120312111(RBL2)
TSR: 106546115(RBL2)
PGUT: 117670949(RBL2)
VKO: 123022200(RBL2)
PMUA: 114602222(RBL2)
ZVI: 118085863(RBL2)
GJA: 107119664(RBL2)
STOW: 125443416(RBL2)
XLA: 108714013(rbl2.L)
XTR: 100490373(rbl2)
NPR: 108789594(RBL2)
RTEM: 120917393(RBL2)
BBUF: 120980560(RBL2)
BGAR: 122920204(RBL2)
DRE: 100331892(rbl2)
SGH: 107555698(rbl2) 107570020
CCAR: 109056327(rbl2) 109073909
CAUA: 113067217(rbl2)
PPRM: 120468061(rbl2)
MAMB: 125246749(rbl2)
IPU: 108275039(rbl2)
PHYP: 113529961(rbl2)
SMEO: 124392650(rbl2)
TFD: 113660033(rbl2)
AMEX: 103033933(rbl2)
EEE: 113573139(rbl2)
TRU: 101070901
LCO: 104938961
ELY: 117262665(rbl2)
EFO: 125887114(rbl2)
SLUC: 116055789(rbl2)
PFLV: 114559995
GAT: 120809130(rbl2)
PPUG: 119196387(rbl2)
MSAM: 119893339(rbl2)
ALAT: 119024274(rbl2)
MZE: 101477072
ONL: 100692495
OAU: 116318646(rbl2)
XMA: 102225329
XCO: 114134429
XHE: 116710227
PRET: 103466787
PFOR: 103148634
PLAI: 106955228
PMEI: 106921954
GAF: 122836164(rbl2)
CVG: 107100404(rbl2)
CTUL: 119781656(rbl2)
GMU: 124857691(rbl2)
NFU: 107389125(rbl2)
KMR: 108229746(rbl2)
ALIM: 106527952(rbl2)
NWH: 119415469(rbl2)
AOCE: 111586657
MCEP: 125015299(rbl2)
POV: 109646631
HHIP: 117762639(rbl2)
HSP: 118110020(rbl2)
LCF: 108885228
SLAL: 111647411 111672285(rbl2)
XGL: 120793598(rbl2) 120793887
BPEC: 110162647
MALB: 109969151
BSPL: 114857016(rbl2)
ELS: 105018165(rbl2) 105023450
SFM: 108932983(rbl2)
PKI: 111832715(rbl2)
AANG: 118215781(rbl2)
LOC: 102685692(rbl2)
ARUT: 117424503(rbl2) 117425692
PSEX: 120535215(rbl2)
LCM: 102352332(RBL2)
CMK: 103176093(rbl2)
RTP: 109915431(rbl2)
BFO: 118417066
SPU: 594490
APLC: 110974703
DCI: 103518861
PPOI: 119096511
TUT: 107361977
PTEP: 107454693
PCAN: 112576730
MMER: 123548615
OBI: 106873599
EPA: 110232421
PDAM: 113665918
 » show all
Reference
PMID:8253384
  Authors
Hannon GJ, Demetrick D, Beach D
  Title
Isolation of the Rb-related p130 through its interaction with CDK2 and cyclins.
  Journal
Genes Dev 7:2378-91 (1993)
DOI:10.1101/gad.7.12a.2378
  Sequence
[hsa:5934]
Reference
PMID:9192872
  Authors
Hurford RK Jr, Cobrinik D, Lee MH, Dyson N
  Title
pRB and p107/p130 are required for the regulated expression of different sets of E2F responsive genes.
  Journal
Genes Dev 11:1447-63 (1997)
DOI:10.1101/gad.11.11.1447
  Sequence
[mmu:19651]
Reference
  Authors
Claudio PP, Tonini T, Giordano A
  Title
The retinoblastoma family: twins or distant cousins?
  Journal
Genome Biol 3:reviews3012 (2002)
DOI:10.1186/gb-2002-3-9-reviews3012
  Sequence
[hsa:5934]
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