ORTHOLOGY: K16439
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Entry
K16439 KO
Symbol
evaE
Name
reductase EvaE
Pathway
map01055
Biosynthesis of vancomycin group antibiotics
map01100
Metabolic pathways
map01110
Biosynthesis of secondary metabolites
map01250
Biosynthesis of nucleotide sugars
Reaction
R06629
Brite
KEGG Orthology (KO) [BR:
ko00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
01055 Biosynthesis of vancomycin group antibiotics
K16439 evaE; reductase EvaE
BRITE hierarchy
Genes
AJA:
AJAP_32025
AMYB:
BKN51_41535
AG:
CAA11764
(evaE)
Taxonomy
UniProt
Reference
PMID:
12596194
Authors
Hubbard BK, Walsh CT.
Title
Vancomycin assembly: nature's way.
Journal
Angew Chem Int Ed Engl 42:730-65 (2003)
DOI:
10.1002/anie.200390202
LinkDB
All DBs
REACTION: R06629
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Entry
R06629 Reaction
Definition
dTDP-L-4-oxovancosamine + NADPH + H+ <=> dTDP-L-epivancosamine + NADP+
Equation
C12320
+
C00005
+
C00080
<=>
C12321
+
C00006
Comment
reductase,EvaE
Reaction class
RC00001
C00005_C00006
RC00261
C12320_C12321
Pathway
rn01055
Biosynthesis of vancomycin group antibiotics
rn01100
Metabolic pathways
rn01110
Biosynthesis of secondary metabolites
rn01250
Biosynthesis of nucleotide sugars
Orthology
K16439
reductase EvaE
LinkDB
All DBs
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integrated database retrieval system