KEGG   ORTHOLOGY: K16514
Entry
K16514                      KO                                     
Symbol
galD
Name
4-oxalomesaconate tautomerase [EC:5.3.2.8]
Pathway
map00362  Benzoate degradation
map01100  Metabolic pathways
map01120  Microbial metabolism in diverse environments
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00362 Benzoate degradation
    K16514  galD; 4-oxalomesaconate tautomerase
Enzymes [BR:ko01000]
 5. Isomerases
  5.3  Intramolecular oxidoreductases
   5.3.2  Interconverting keto- and enol-groups
    5.3.2.8  4-oxalomesaconate tautomerase
     K16514  galD; 4-oxalomesaconate tautomerase
Other DBs
RN: R07839
COG: COG2828
Genes
KPN: KPN_04047
KPU: KP1_5416
KPM: KPHS_52170
KPP: A79E_0060
KPH: KPNIH24_25955
KPZ: KPNIH27_24940
KPV: KPNIH29_25900
KPW: KPNIH30_26295
KPY: KPNIH31_25370
KPG: KPNIH32_27160
KPR: KPR_0060
KPJ: N559_0096
KPX: PMK1_01553(galD)
KPNU: LI86_00300
KPNK: BN49_0060
KVA: Kvar_0052
KPE: KPK_0046
CRO: ROD_31661
CAMA: F384_17455
SPE: Spro_2090
SMAF: D781_1917
RAA: Q7S_13295
EAM: EAMY_1951(fldA3)
EAY: EAM_1908
EBI: EbC_05340
XCC: XCC4031(fldA)
XCB: XC_4120
XCP: XCR_0229
XCV: XCV4254
XAX: XACM_4026
XAC: XAC4156(fldA)
XCI: XCAW_00142(fldA)
XOM: XOO4300(XOO4300)
XOO: XOO4563(fldA)
XOP: PXO_03236(fldA)
XOR: XOC_0385
XPH: XppCFBP6546_13625(XppCFBP6546P_13625)
XHD: LMG31886_42480(ligU)
PCQ: PcP3B5_13880(galD)
PPU: PP_2513(gllD)
PPI: YSA_00540
PPX: T1E_3401
PPUT: L483_20180
PPUN: PP4_26410
PFL: PFL_2685
PPRO: PPC_2729
PSTT: CH92_18155
PSOS: POS17_2676(PFL_2685)
PSIL: PMA3_18990
PAT: Patl_3889
CSA: Csal_0328
AJP: AMJAP_1186(galD)
RFO: REIFOR_00530(prpF)
SALN: SALB1_0066
PSE: NH8B_2727
RSY: RSUY_46200(galD)
RME: Rmet_3706
BPH: Bphy_3209
PPNO: DA70_15090
PPNM: LV28_15590
PPUL: RO07_09635
PSPU: NA29_05550
PAPI: SG18_10135
PLG: NCTC10937_01989(mii_2)
HYF: DTO96_100888(galD)
BHO: D560_0871
BHM: D558_0857
BHZ: ACR54_03617(galD)
AFQ: AFA_05545
PNA: Pnap_2033
PVAC: HC248_00679(galD)
DAC: Daci_4451
LIM: L103DPR2_01491(galD_2)
URU: DSM104443_02502(ligU)
ABRE: pbN1_38990
AZO: azo2544(fldA)
AOA: dqs_2701
TCL: Tchl_1057
AVP: AVENP_2169(galD)
AMIH: CO731_01870(galD)
SME: SMc00497
SMX: SM11_chr1630(fldA)
SMER: DU99_09680
ARA: Arad_2914
RLE: RL2850
RPA: RPA4696(FldA)
RPB: RPB_0878
RPD: RPD_0988
RPE: RPE_0745
RPT: Rpal_5177
PHL: KKY_3765
LABT: FIU93_13990(galD)
MALG: MALG_02282
ROT: FIV09_09365(galD)
MALU: KU6B_25080(fldA) KU6B_53780
PMAU: CP157_03180(galD)
NAR: Saro_2818
SMAZ: LH19_17720
SPHI: TS85_18490
SSAN: NX02_17530
SSY: SLG_12560
SPHR: BSY17_3452
SFLA: SPHFLASMR4Y_02982(galD)
BLAS: BSY18_3518
ALB: AEB_P0248
AAY: WYH_01903(galD)
ADO: A6F68_01085(galD)
MAG: amb0250
MAGX: XM1_1086
MAGN: WV31_13590
MAGQ: MGMAQ_2664
MSHG: MSG_02375
SALB: XNR_3396
SMAL: SMALA_0372
SFA: Sfla_3395
STRP: F750_3341(prpF)
SLE: sle_08620(sle_08620)
SGM: GCM10017557_09430(fldA)
STRD: NI25_00245
SGE: DWG14_01306(galD)
MLV: CVS47_03113(galD)
AMIN: AUMI_19420
AUW: AURUGA1_00416(galD)
ACH: Achl_3362
NCX: Nocox_11635(galD)
MMAR: MODMU_2828
PSEE: FRP1_23145
ACTN: L083_3806
AIH: Aiant_15050(fldA)
SLI: Slin_4025
 » show all
Reference
  Authors
Nogales J, Canales A, Jimenez-Barbero J, Serra B, Pingarron JM, Garcia JL, Diaz E
  Title
Unravelling the gallic acid degradation pathway in bacteria: the gal cluster from Pseudomonas putida.
  Journal
Mol Microbiol 79:359-74 (2011)
DOI:10.1111/j.1365-2958.2010.07448.x
  Sequence
[ppu:PP_2513]
LinkDB

KEGG   ENZYME: 5.3.2.8
Entry
EC 5.3.2.8                  Enzyme                                 
Name
4-oxalomesaconate tautomerase;
GalD
Class
Isomerases;
Intramolecular oxidoreductases;
Interconverting keto- and enol-groups
Sysname
4-oxalomesaconate keto---enol-isomerase
Reaction(IUBMB)
(1E)-4-oxobut-1-ene-1,2,4-tricarboxylate = (1E,3E)-4-hydroxybuta-1,3-diene-1,2,4-tricarboxylate [RN:R07839]
Reaction(KEGG)
R07839
Substrate
(1E)-4-oxobut-1-ene-1,2,4-tricarboxylate [CPD:C04434]
Product
(1E,3E)-4-hydroxybuta-1,3-diene-1,2,4-tricarboxylate [CPD:C04324]
Comment
This enzyme has been characterized from the bacterium Pseudomonas putida KT2440 and is involved in the degradation pathway of syringate and 3,4,5-trihydroxybenzoate. It catalyses the interconversion of two of the tautomers of 4-oxalomesaconate, a reaction that can also occur spontaneously.
History
EC 5.3.2.8 created 2011 as EC 5.3.3.16, modified 2011, transferred 2012 to EC 5.3.2.8
Pathway
ec00362  Benzoate degradation
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K16514  4-oxalomesaconate tautomerase
Genes
KPNKPN_04047
KPUKP1_5416
KPMKPHS_52170
KPPA79E_0060
KPHKPNIH24_25955
KPZKPNIH27_24940
KPVKPNIH29_25900
KPWKPNIH30_26295
KPYKPNIH31_25370
KPGKPNIH32_27160
KPCKPNIH10_25925
KPQKPR0928_25440
KPTVK055_3418
KPOKPN2242_23315
KPRKPR_0060
KPJN559_0096
KPID364_20690
KPAKPNJ1_00063
KPSKPNJ2_00064
KPXPMK1_01553(galD)
KPBFH42_16625
KPNEKU54_000300
KPNULI86_00300
KPNKBN49_0060
KVAKvar_0052
KPEKPK_0046
KVDKR75_07865
KVQSP68_14465
KMIVW41_14210
KQUAVR78_04135
KQVB8P98_00295
KARLGL98_00285
RORRORB6_19055
RPLNB1209_00300
RAODSD31_00335
CROROD_31661
CAMAF384_17455
CFARCI104_02845
CTELGBC03_28070
KASKATP_00640
IZHFEM41_02410
EBUCUC76_15890
SPESpro_2090
SMAFD781_1917
SFGAV650_17155
SRZAXX16_3212
SERASer39006_020450
SERQCWC46_20455
SERMCLM71_09505
SQUE4343_05755
SFJSAMEA4384070_2150(mii)
SRHZFO014_00035
RAHRahaq_2669
RACEJHW33_03825
RAAQ7S_13295
ROXBV494_03500
RVCJ9880_20315
RBADH2866_00175
PBRAB5S52_08155
BGJAWC36_13660
SODSant_P0186
EAMEAMY_1951(fldA3)
EAYEAM_1908
EBIEbC_05340
PAOPat9b_5774
KLNLH22_12875
PANSFCN45_11150
TCIA7K98_11230
XCCXCC4031(fldA)
XCBXC_4120
XCAxcc-b100_4224
XCPXCR_0229
XCVXCV4254
XAXXACM_4026
XACXAC4156(fldA)
XCIXCAW_00142(fldA)
XCTJ151_04334
XCJJ158_04287
XCUJ159_04283
XCNJ169_04331
XCWJ162_04289
XCRJ163_04284
XCMJ164_04284
XCFJ172_04324
XFUXFF4834R_chr40260
XAOXAC29_20925
XOMXOO4300(XOO4300)
XOOXOO4563(fldA)
XOPPXO_03236(fldA)
XOYAZ54_24060
XORXOC_0385
XOZBE73_22475
XVEBJD12_11490
XPEBJD13_18245
XHRXJ27_14470
XGABI317_01990
XPHXppCFBP6546_13625(XppCFBP6546P_13625)
XANAC801_20680
XARXB05_15695
XEUXSP_003901
XHDLMG31886_42480(ligU)
SRHBAY15_1810
SLMBIZ42_18430
LRZBJI69_03980
LPYFIV34_03340
VNAPN96_18535
VEJVEJY3_18101
VFLAL536_10300
VZIG5S32_20205
PCQPcP3B5_13880(galD)
PPUPP_2513(gllD)
PPFPput_1360 Pput_3205
PPWPputW619_2026
PPBPPUBIRD1_3171
PPIYSA_00540
PPXT1E_3401
PPUTL483_20180
PPUNPP4_26410
PFLPFL_2685
PPRCPFLCHA0_c27490
PPROPPC_2729
PFEPSF113_3478
PSTTCH92_18155
PLULFOB45_15895
PCPJM49_17375
PSOSPOS17_2676(PFL_2685)
PPSLBJP27_21275
PSILPMA3_18990
PEZHWQ56_20090
AVNAvin_31290
AVLAvCA_31290
AVDAvCA6_31290
EMODM558_04810
ATNFM020_08435
SYKKDN34_01870
PATPatl_3889
PCARPC2016_2104
AAWAVL56_08880
ALRDS731_08765
CSACsal_0328
MMWMmwyl1_3941
MMEMarme_0833
MPCMar181_0381
MPRIMP3633_0449
MARDIBG28_02950
MFOIJSY38_12235
MPRFJ8N69_06140
MARSA8C75_18855
MGEOCFI10_14885
AJPAMJAP_1186(galD)
GSNYC6258_04098
RFOREIFOR_00530(prpF)
SALNSALB1_0066
NAQD0T90_09285
NBLGJV52_09185
NWXCGZ65_09115
VITADP71_27500
CHROCXB49_01570
PSENH8B_2727
AMAHDLM_2052 DLM_2160
AQSDKK66_18690
RSLRPSI07_mp1415
RSYRSUY_46200(galD)
RSGJK151_12000
RMERmet_3706
BGFBC1003_5347
BUQAC233_29265
BPHBphy_3209
PGPCUJ91_26930
PCJCUJ87_23800
PTROG5S35_33695
PPKU875_22410
PPNODA70_15090
PPNMLV28_15590
PRBX636_11755
PPULRO07_09635
PSPUNA29_05550
PAPISG18_10135
PVEUC34_01420
POXMB84_05755
PTXABW99_00690 ABW99_15645
PFGAB870_12675
PNRAT302_09320
PANDDRB87_01285
PFIBPI93_001240
PLGNCTC10937_01989(mii_2)
HYFDTO96_100888(galD)
BHOD560_0871
BHMD558_0857
BHZACR54_03617(galD)
BBROBAU06_12660
BFZBAU07_13775
BOHAKI39_11970
PUSCKA81_10460
PUDG9Q38_04095
CDNBN940_08531
AFQAFA_05545
AAQUD3M96_07085
PHNPAEH1_07135
OUEI6G29_08360
PIGEGT29_06630 EGT29_21015
PARKLSG25_04765
PNAPnap_2033
PVACHC248_00679(galD)
ACIDCBP33_05220
ACIPCBP36_05670
ACINCBP34_05055
ACISCBP35_13270
AANTHUK68_11005
DACDaci_4451
DELDelCs14_2353
DTSBI380_01365
DHKBO996_20130
DLAI6G47_02105
LIML103DPR2_01491(galD_2)
HEEhmeg3_19340
HHFE2K99_06690
MASWAM586_11750
MALIEYF70_25845
MUMFCL38_23505
MFLAGO485_19015
DUGHH213_29560
XYKGT347_25765
URUDSM104443_02502(ligU)
ARESIWH25_16400
ABREpbN1_38990
APETToN1_04080 ToN1_04220
AZOazo2544(fldA)
AOAdqs_2701
ACOMCEW83_02940 CEW83_03000
AZRCJ010_16090 CJ010_16430 CJ010_16495
THUAC731_016785
TCLTchl_1057
TAKTharo_1098
AZQG3580_09895 G3580_09965
AVPAVENP_2169(galD)
MESRFGU64_09810
MESOBSQ44_13010
AMIHCO731_01870(galD)
NIYFQ775_19485
ORMHTY61_05170
SMESMc00497
SMKSinme_1674
SMQSinmeB_1519
SMXSM11_chr1630(fldA)
SMEGC770_GR4Chr1821
SMELSM2011_c00497
SMERDU99_09680
ARAArad_2914
ALFCFBP5473_15980
REIIE4771_PB00100
RLERL2850
RHRCKA34_29830
RIIFFM53_023765
RLSHB780_17725
NGLRG1141_CH37830
NGGRG540_CH38480
NEOCYG48_14360
NENNCHU2750_16650
RHTNT26_0688 NT26_3187
RFVRFYW14_03200
RPARPA4696(FldA)
RPBRPB_0878
RPDRPD_0988
RPERPE_0745
RPTRpal_5177
RPXRpdx1_4871
BOPAXW83_08325
BOIBLM15_26405
BOFFQV39_22230
RHJHZY79_11975
PHLKKY_3765
DEQXM25_18675
DEAFPZ08_03370
YTIFNA67_00325
MAADAZF01_20430
MLUTJET14_00620
BRND1F64_00895 D1F64_21830
PPHRAPZ00_03795
LAPACP90_08350
LABTFIU93_13990(galD)
LAGGB0E33_20415
PSTGE8M01_14355
ACUTMRB58_02065
BSBBresu_2120
BGOEIFJ75_11205
AEXAstex_2408
RUAD1823_11235
MALGMALG_02282
YPACCEW88_19485
YANAYJ57_18380
SULZC1J03_00900
SPOTG6548_05065
AHTANTHELSMS3_00927 ANTHELSMS3_03530 ANTHELSMS3_03819
OCDFHY55_07540 FHY55_13935
ROTFIV09_09365(galD)
MALUKU6B_25080(fldA) KU6B_53780
TGLHFZ77_06450
PYEA6J80_20765
PAROCUV01_03965
PAMNJCM7685_2362
PPANESD82_14315
PLIAE4191_23195
PMAUCP157_03180(galD)
PTPRCA23_c08340
DAAAKL17_0078
THWBMG03_15475
RBGBG454_07490
GFUKM031_19330
SALOEF888_06825 EF888_14025
SEDIEBB79_03585
PSEBEOK75_20070
PSHQF3W81_14645
PGVSL003B_2855
CACTHZ995_05385
CMAGCBW24_02310 CBW24_17060
NARSaro_2818
NPPPP1Y_Mpl10392
NPNJI59_20865
NREBES08_28955
NOVTQ38_025050 TQ38_028385
NOTC7W88_02295
NORFA702_07580
NDRHT578_08995 HT578_09580
SMAZLH19_17720
RDICMV14_06860
SPHITS85_18490
SSANNX02_17530
SPANAWL63_08200
SKRBRX40_12215
SPHCCVN68_17270
SSUAFPZ54_06175
SCHSphch_3892
SSYSLG_12560
SPHBEP837_03486
SPHRBSY17_3452
SHYDCJD35_16795 CJD35_19545
SYAA6768_17505
SPYGYGS_C2P1465
SAMISAMIE_1030470
SPHGAZE99_04475
SFLASPHFLASMR4Y_02982(galD)
SPHYCHN51_00925
BLASBSY18_3518
BFWB5J99_08385
SPHSETR14_07955
POQKZX46_07360
ALBAEB_P0248
AAYWYH_01903(galD)
ADOA6F68_01085(galD)
CMANA9D14_17215
POTE2E27_18090
ABSAZOBR_p310191
ABQABAZ39_27975
AZTTSH58p_32555
NCBC0V82_22470
MAGamb0250
MAGXXM1_1086
MAGNWV31_13590
THACCSC3H3_01150 CSC3H3_15795 CSC3H3_21875
MAGQMGMAQ_2664
APBSAR116_0938
PARHI5S86_11470
MKNMKAN_15650
MGOAFA91_01480
MSHGMSG_02375
NTPCRH09_08940
ROAPd630_LPD00179
SALBXNR_3396
SMASAVERM_1616
SSXSACTE_0143
SVLStrvi_5288
SRCM271_45995
SMALSMALA_0372
SSOII1A49_05380
SFASfla_3395
STRPF750_3341(prpF)
SCWTU94_29780
SXISXIM_52150
SCXAS200_08340
STRFASR50_30565
SLEsle_08620(sle_08620)
SKYD0C37_14350
SGMGCM10017557_09430(fldA)
SLSSLINC_7291
STRDNI25_00245
SAUOBV401_05620
SNZDC008_30120
SGEDWG14_01306(galD)
SGDELQ87_04760
SCYAEJ357_41225
SASTCD934_02875
SFYGFH48_04165
SAQUEJC51_40085
SFUGCNQ36_03730
SCHACP983_05325
SFEUIM697_27680
SVDCP969_30925
SPRACP972_00295
SACTDMT42_32985
MAURBOH66_06375
MLVCVS47_03113(galD)
MWAE4K62_17610
MPRTET475_01800
MSEDE3O41_03745
MCAWF6J84_14335
MLZF6J85_16700
MCHNHCR76_14750
MICSC1N74_09930
AARCG127AT_10880
AMINAUMI_19420
AUMAURMO_01272
AUWAURUGA1_00416(galD)
AJGKKR91_02695
ACHAchl_3362
PSNINIBR502771_05720
SATKSA2016_1318
MUZH4N58_01865
ACTWF7P10_28290
NOABKM31_31875
NCXNocox_11635(galD)
NGNLCN96_13380
BSDBLASA_2605
MMARMODMU_2828
AMQAMETH_2205
AACDLWP59_32620
PSEEFRP1_23145
PSEQAD006_02330
PECQAD017_10155
PHHAFB00_07655
PMADBAY61_21980
ACTNL083_3806
AIHAiant_15050(fldA)
AFLOHEQ12_08575
SLISlin_4025
SPIBG8759_04365
RSIRunsl_1543
RUNDR864_16580
EOLEmtol_3451
 » show all
Reference
1  [PMID:21219457]
  Authors
Nogales J, Canales A, Jimenez-Barbero J, Serra B, Pingarron JM, Garcia JL, Diaz E
  Title
Unravelling the gallic acid degradation pathway in bacteria: the gal cluster from Pseudomonas putida.
  Journal
Mol Microbiol 79:359-74 (2011)
DOI:10.1111/j.1365-2958.2010.07448.x
  Sequence
[ppu:PP_2513]
Other DBs
ExplorEnz - The Enzyme Database: 5.3.2.8
IUBMB Enzyme Nomenclature: 5.3.2.8
ExPASy - ENZYME nomenclature database: 5.3.2.8
BRENDA, the Enzyme Database: 5.3.2.8
LinkDB

KEGG   REACTION: R07839
Entry
R07839                      Reaction                               
Name
4-oxalomesaconate keto---enol-isomerase
Definition
(1E)-4-Oxobut-1-ene-1,2,4-tricarboxylate <=> (1E,3E)-4-Hydroxybuta-1,3-diene-1,2,4-tricarboxylate
Equation
Reaction class
RC02426  C04324_C04434
Enzyme
Pathway
rn00362  Benzoate degradation
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
Orthology
K16514  4-oxalomesaconate tautomerase [EC:5.3.2.8]
Other DBs
RHEA: 28934
LinkDB

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